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    "ocrText": "2017-0029-F\n[\n]\nThursday, May 30, 2019\nFOIA Marker\nThis is not a textual record. This FOIA Marker indicates that material has been removed\nduring FOIA processing by George W. Bush Presidential Library staff.\nDomestic Policy Council\nZinsmeister, W. Karl - Subject Files\nLocation or\nNARA Number:\nFRC ID:\nOA Number:\nStack: Row: Sect.: Shelf: Pos.:\nHollinger ID:\nW\n31\n24\n6\n7\n14303\n88293\n14062\n14165\nFolder Title:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nWithdrawn/Redacted Material\nThe George W. Bush Library\nDOCUMENT\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nNO.\n001\nEmail\n[Email] - To: Karl Rove - From: Karl Zinsmeister\n2\n06/13/2007\nP5; P6/b6;\n002\nDraft\n[Draft]\n2\nN.D.\nP5;\n003\nEmail\nRE: Stem Cell Event - To: Karl Zinsmeister\n1\n06/14/2007\nP5;\n004\nEmail\nTuesday Meetings? - To: Karl Zinsmeister - From:\n1\n06/18/2007\nP5;\nChristopher Papagianis\n005\nHandwritten Note\nS.C. Principals' Mtg Notes\n2\n06/2007\nP5;\n006\nDraft\nFrame\n1\nN.D.\nP5;\n007\nEmail\nS.5 Veto Statement - To: John Marburger - From: Karl\n1\n06/12/2007\nP5;\nZinsmeister\nCOLLECTION TITLE:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\n14303\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to EOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nPage 1 of 4\nThis document was prepared on Thursday, May 30, 2019\n2014-0503-F\n2017-0029-F\nWithdrawn/Redacted Material\nThe George W. Bush Library\nDOCUMENT FORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nNO.\n008\nEmail\nRE: OSTP Comments to Veto Statement - To:\n1\n06/12/2007\nP5;\nChristopher Papagianis - From: Karl Zinsmeister\n009\nEmail\nRE: - To: Karl Zinsmeister - From: Kevin Sullivan\n1\n06/18/2007\nP5;\n010\nEmail\nRE: Stem Cell Qs - To: Karl Zinsmeister, et al. - From:\n1\n06/18/2007\nP5;\nChristopher Papagianis\n011\nEmail\nRE: Stem Cell Guidance - To: Karl Zinsmeister, et al. -\n1\n06/18/2007\nP5;\nFrom: John Marburger\n012\nEmail\nRE: Stem Cell Guidance - To: John Marburger, et al. -\n3\n06/18/2007\nP5;\nFrom: Karl Zinsmeister\n013\nDraft\n[Draft]\n2\nN.D.\nP5;\nCOLLECTION TITLE:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\n14303\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nPage 2 of 4\n2014-0503-F\nThis document was prepared on Thursday, May 30, 2019\n2017-0029-F\nWithdrawn/Redacted Material\nThe George W. Bush Library\nDOCUMENT FORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nNO.\n014\nHandwritten Note [Notes]\n1\nN.D.\nP5;\n015\nDraft\nDraft Statement by the President\n2\n06/07/2007\nP5;\n016\nEmail\nFOR REVIEW - Draft Statement on Passage of Stem Cell\n2\n06/06/2007 P5;\nBill - To: VP Staff Sec, et al. - From: Thomas Bowman\n017\nEmail\nRe: Patients and Statement - To: Christopher\n3\n06/06/2007\nP5;\nPapagianis - From: Karl Zinsmeister\n018\nEmail\nRe: EO - To: Christopher Papagianis - From: Karl\n1\n06/06/2007 P5;\nZinsmeister\n019\nHandwritten Note\n[Notes]\n1\nN.D.\nP5;\nCOLLECTION TITLE:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\n14303\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\n2014-0503-F\nPage 3 of 4\nThis document was prepared on Thursday, May 30, 2019\n2017-0029-F\nWithdrawn/Redacted Material\nThe George W. Bush Library\nDOCUMENT FORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nNO.\n020\nEmail\n[Email] - To: Karl Zinsmeister - From: Christopher\n1\n06/06/2007\nP5;\nPapagianis\n021\nEmail\nStatement by the President - To: Christopher Papagianis\n2\n04/11/2007\nP5;\n022\nEmail\nToday's Stem Cell Papers - To: Christopher Papagianis -\n1\n06/06/2007\nP5;\nFrom: Yuval Levin\n023\nEmail\nRE: - To: Christopher Papagianis - From: Tevi Troy\n1\n06/06/2007\nP5;\nCOLLECTION TITLE:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\n14303\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information |(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRAJ\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nPage 4 of 4\n2014-0503-F\nThis document was prepared on Thursday, May 30, 2019\n2017-0029-F\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nEmail\n[Email] - To: Karl Rove - From: Karl Zinsmeister\n2\n06/13/2007\nP5; P6/b6;\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\n110TH CONGRESS\n1ST SESSION\nS.5\nAN ACT\nTo amend the Public Health Service Act to provide for\nhuman embryonic stem cell research.\n1\nBe it enacted by the Senate and House of Representa-\n2 tives of the United States of America in Congress assembled,\n3 SECTION 1. SHORT TITLE.\n4\nThis Act may be cited as the \"Stem Cell Research\n5 Enhancement Act of 2007\".\n2\n1 SEC. 2. HUMAN EMBRYONIC STEM CELL RESEARCH.\n2\nPart H of title IV of the Public Health Service Act\n3 (42 U.S.C. 289 et seq.) is amended by inserting after sec-\n4 tion 498C the following:\n5 \"SEC. 498D. HUMAN EMBRYONIC STEM CELL RESEARCH.\n6\n\"(a) IN GENERAL-Notithstanding any other pro-\n7 vision of law (including any regulation or guidance), the\n8 Secretary shall conduct and support research that utilizes\n9 human embryonic stem cells in accordance with this sec-\n10 tion (regardless of the date on which the stem cells were\n11 derived from a human embryo)\n12\n\"(b) ETHICAL REQUIREMENTS.-Human embryonic\n13 stem cells shall be eligible for use in any research con-\n14 ducted or supported by the Secretary if the cells meet each\n15 of the following:\n16\n\"(1) The stem cells were derived from human\n17\nembryos that have been donated from in vitro fer-\n18\ntilization clinics, were created for the purposes of\n19\nfertility treatment, and were in excess of the clinical\n20\nneed of the individuals seeking such treatment.\n21\n\"(2) Prior to the consideration of embryo dona-\n22\ntion and through consultation with the individuals\n23\nseeking fertility treatment, it was determined that\n24\nthe embryos would never be implanted in a woman\n25\nand would otherwise be discarded.\nt S 5 ES\n3\n1\n\"(3) The individuals seeking fertility treatment\n2\ndonated the embryos with written informed consent\n3\nand without receiving any financial or other induce-\n4\nments to make the donation.\n5\n\"(c) GUIDELINES.-Not later than 60 days after the\n6 date of the enactment of this section, the Secretary, in\n7 consultation with the Director of NIH, shall issue final\n8 guidelines to carry out this section.\n9\n\"(d) REPORTING REQUIREMENTS.-The Secretary\n10 shall annually prepare and submit to the appropriate com-\n11 mittees of the Congress a report describing the activities\n12 carried out under this section during the preceding fiscal\n13 year, and including a description of whether and to what\n14 extent research under subsection (a) has been conducted\n15 in accordance with this section.\"\n16 SEC. 3. ALTERNATIVE HUMAN PLURIPOTENT STEM CELL\n17\nRESEARCH.\n18\nPart H of title IV of the Public Health Service Act\n19 (42 U.S.C. 284 et seq.), as amended by section 2, is fur-\n20 ther amended by inserting after section 498D the fol-\n21 lowing:\n22 \"SEC. 498E. ALTERNATIVE HUMAN PLURIPOTENT STEM\n23\nCELL RESEARCH.\n24\n\"(a) IN GENERAL.-In accordance with section 492,\n25 the Secretary shall conduct and support basic and applied\ntS 5 ES\n4\n1 research to develop techniques for the isolation, derivation,\n2 production, or testing of stem cells that, like embryonic\n3 stem cells, are capable of producing all or almost all of\n4 the cell types of the developing body and may result in\n5 improved understanding of or treatments for diseases and\n6 other adverse health conditions, but are not derived from\n7 a human embryo.\n8\n\"(b) GUIDELINES.-Not later than 90 days after the\n9 date of the enactment of this section, the Secretary, after\n10 consultation with the Director, shall issue final guidelines\n11 to implement subsection (a), that-\n12\n\"(1) provide guidance concerning the next steps\n13\nrequired for additional research, which shall include\n14\na determination of the extent to which specific tech-\n15\nniques may require additional basic or animal re-\n16\nsearch to ensure that any research involving human\n17\ncells using these techniques would clearly be con-\n18\nsistent with the standards established under this sec-\n19\ntion;\n20\n\"(2) prioritize research with the greatest poten-\n21\ntial for near-term clinical benefit; and\n22\n\"(3) consistent with subsection (a), take into\n23\naccount techniques outlined by the President's Coun-\n24\ncil on Bioethics and any other appropriate tech-\n25\nniques and research.\ntS 5 ES\n5\n1\n\"(c) REPORTING REQUIREMENTS.-Not later than\n2 January 1 of each year, the Secretary shall prepare and\n3 submit to the appropriate committees of the Congress a\n4 report describing the activities carried out under this sec-\n5 tion during the fiscal year, including a description of the\n6 research conducted under this section.\n7\n\"(d) RULE OF CONSTRUCTION.-Nothing in this sec-\n8 tion shall be construed to affect any policy, guideline, or\n9 regulation regarding embryonic stem cell research, human\n10 cloning by somatic cell nuclear transfer, or any other re-\n11 search not specifically authorized by this section.\n12\n\"(e) DEFINITION.-\n13\n\"(1) IN GENERAL.-In this section, the term\n14\n'human embryo' shall have the meaning given such\n15\nterm in the applicable appropriations Act.\n16\n\"(2) APPLICABLE ACT.-For purposes of para-\n17\ngraph (1), the term 'applicable appropriations Act'\n18\nmeans, with respect to the fiscal year in which re-\n19\nsearch is to be conducted or supported under this\n20\nsection, the Act making appropriations for the De-\n21\npartment of Health and Human Services for such\n22\nfiscal year, except that if the Act for such fiscal year\n23\ndoes not contain the term referred to in paragraph\n24\n(1), the Act for the previous fiscal year shall be\n25\ndeemed to be the applicable appropriations Act.\nt S 5 ES\n6\n1\n\"(f) AUTHORIZATION OF APPROPRIATIONS.-There\n2 is authorized to be appropriated such sums as may be nec-\n3 essary for each of fiscal years 2008 through 2010, to carry\n4 out this section.\"\nPassed the Senate April 11, 2007.\nAttest:\nSecretary.\ntS 5 ES\nEXECUTIVE OFFICE OF THE PRESIDENT\nOFFICE OF MANAGEMENT AND BUDGET\nWASHINGTON, D.C. 20503\nApril 10, 2007\n(Senate)\nSTATEMENT OF ADMINISTRATION POLICY\nS.5 - Stem Cell Research Enhancement Act of 2007\n(Sen. Reid (D) NV and 39 cosponsors)\nThe Administration strongly opposes Senate passage of S. 5, which would use Federal taxpayer\ndollars to support and encourage the destruction of human life for research. The bill would\ncompel all American taxpayers to pay for research that relies on the intentional destruction of\nhuman embryos for the derivation of stem cells, overturning the President's policy that funds\nresearch without promoting such ongoing destruction. If S. 5 were presented to the President, he\nwould veto the bill.\nThe President strongly supports medical research and has worked with Congress to increase\nresources for the National Institutes of Health. This Administration is the first to provide Federal\nfunds for human embryonic stem cell research and has done so without encouraging the\ndestruction of human embryos. The President's policy permits the Federal funding of research\nusing embryonic cell lines created prior to August 9, 2001, the date his policy was announced,\nalong with stem cell research using other kinds of cell lines. Scientists can therefore explore the\npotential applications of such cells, but the Federal government does not offer incentives or\nencouragement for the destruction of human life.\nOver the past six years, more than $130 million in taxpayer dollars has been devoted to human\nembryonic stem cell research consistent with the President's policy. Overall, more than $3\nbillion has gone to innovative research on all forms of stem cells, contributing to proven medical\ntreatments that use human stem cells from adult and other non-embryonic sources. S.5 seeks to\nreplace the Administration's policy by providing Federal funding for the first time for a line of\nresearch that involves the intentional destruction of living human embryos for the derivation of\ntheir cells. Destroying nascent human life for research raises serious ethical problems, and\nmillions of Americans consider the practice immoral. The Administration believes that\ngovernment has a duty to use the people's money responsibly, both supporting important public\npurposes and respecting moral boundaries.\nAlternative types of human stem cells - drawn from adults, children, umbilical-cord blood, and\nother non-embryonic sources, without doing harm to the donors - have already achieved\ntherapeutic results in thousands of patients with many different diseases. Moreover, a recent\nseries of encouraging research reports offer hope that stem cells drawn from non-embryonic\nsources may possess characteristics like those of embryonic stem cells. In addition, researchers\nare now working to develop promising new techniques to produce stem cells similar in nature to\nthose derived from human embryos, but without harming or destroying embryos.\nS.5 clearly acknowledges the potential of these new advances and the importance of supporting\nthem. The provisions in the bill to promote research leading to new techniques for deriving the\nfunctional equivalent of embryonic stem cells, without harming or destroying human embryos,\nencourage science that is not in conflict with ethics.\nUnfortunately, the bill then crosses that same ethical line, by proposing to use taxpayer dollars to\nencourage destruction of nascent human life for research. The Administration believes that\nresearch on alternative sources of stem cells is extremely promising and provides robust\nopportunities to advance science without compelling American taxpayers to participate in\nongoing destruction of human embryos.\nMoreover, private sector support and public funding by several States for this line of research,\nwhich will add up to several billion dollars in the coming few years, argue against the notion of\nany urgent shortfall of research funding. Whatever one's view of the ethical issues or the state of\nthe research, the future of this field does not require a policy of Federal subsidies that is\noffensive to the moral principles of millions of Americans.\nThe President believes that by enacting appropriate policy safeguards while encouraging the\ndevelopment of novel scientific techniques, it is possible to advance scientific and medical\nfrontiers without violating moral principles. S.5 fails to find that balance and is therefore deeply\ntroubling to millions of Americans. The President urges Congress to pass an alternative bill that\nwould advance stem cell research without encouraging destruction of human life.\n*****\n2\n110TH CONGRESS\n1ST SESSION\nS.30\nAN ACT\nTo intensify research to derive human pluripotent stem cell\nlines.\n1\nBe it enacted by the Senate and House of Representa-\n2 tives of the United States of America in Congress assembled,\n3 SECTION 1. SHORT TITLE.\n4\nThis Act may be cited as the \"Hope Offered through\n5 Principled and Ethical Stem Cell Research Act\" or the\n6 \"HOPE Act\".\n2\n1 SEC. 2. PURPOSES.\n2\nIt is the purpose of this Act to-\n3\n(1) intensify research that may result in im-\n4\nproved understanding of or treatments for diseases\n5\nand other adverse health conditions; and\n6\n(2) promote the derivation of pluripotent stem\n7\ncell lines without the creation of human embryos for\n8\nresearch purposes and without the destruction or\n9\ndiscarding of, or risk of injury to, a human embryo\n10\nor embryos other than those that are naturally dead.\n11 SEC. 3. HUMAN PLURIPOTENT STEM CELL RESEARCH.\n12\nPart H of title IV of the Public Health Service Act\n13 (42 U.S.C. 289 et seq.) is amended by inserting after see-\n14 tion 498C the following:\n15 \"SEC. 498D. HUMAN PLURIPOTENT STEM CELL RESEARCH.\n16\n\"(a) IN GENERAL.-The Secretary shall conduct and\n17 support basic and applied research to develop techniques\n18 for the isolation, derivation, production, or testing of stem\n19 cells, including pluripotent stem cells that have the flexi-\n20 bility of embryonic stem cells (whether or not they have\n21 an embryonic source), that may result in improved under-\n22 standing of or treatments for diseases and other adverse\n23 health conditions, provided that the isolation, derivation,\n24 production, or testing of such cells will not involve-\n25\n\"(1) the creation of a human embryo or em-\n26\nbryos for research purposes; or\ntS 30 ES\n3\n1\n\"(2) the destruction or discarding of, or risk of\n2\ninjury to, a human embryo or embryos other than\n3\nthose that are naturally dead.\n4\n\"(b) GUIDELINES.-Not later than 90 days after the\n5 date of the enactment of this section, the Secretary, after\n6 consultation with the Director of NIH, shall issue final\n7 guidelines that-\n8\n\"(1) provide guidance concerning the next steps\n9\nrequired for additional research, which shall include\n10\na determination of the extent to which specific tech-\n11\nniques may require additional animal research to en-\n12\nsure that any research involving human cells using\n13\nthese techniques would clearly be consistent with the\n14\nstandards established under subsection (a);\n15\n\"(2) prioritize research with the greatest poten-\n16\ntial for near-term clinical benefit;\n17\n\"(3) consistent with standards established\n18\nunder subsection (a), take into account techniques\n19\noutlined by the President's Council on Bioethics and\n20\nany other appropriate techniques and research; and\n21\n\"(4) in the case of research involving stem cells\n22\nfrom a naturally dead embryo, require assurances\n23\nfrom grant applicants that no alteration of the tim-\n24\ning, methods, or procedures used to create, main-\n25\ntain, or intervene in the development of a human\nt S 30 ES\n4\n1\nembryo was made solely for the purpose of deriving\n2\nthe stem cells.\n3\n\"(c) REPORTING REQUIREMENTS.-Not later than\n4 January 1 of each year, the Secretary shall prepare and\n5 submit to the appropriate committees of the Congress a\n6 report describing the activities carried out under this sec-\n7 tion during the fiscal year, including a description of the\n8 research conducted under this section.\n9\n\"(d) RULE OF CONSTRUCTION.-Nothing in this sec-\n10 tion shall be construed as altering the policy in effect on\n11 the date of enactment of this section regarding the eligi-\n12 bility of stem cell lines for funding by the National Insti-\n13 tutes of Health.\n14\n\"(e) AUTHORIZATION OF APPROPRIATIONS.-There\n15 is authorized to be appropriated such sums as may be nec-\n16 essary to carry out this section.\n17\n\"(f) DEFINITIONS.-In this section:\n18\n\"(1) NATURALLY DEAD.-The term 'naturally\n19\ndead' means having naturally and irreversibly lost\n20\nthe capacity for integrated cellular division, growth,\n21\nand differentiation that is characteristic of an orga-\n22\nnism, even if some cells of the former organism may\n23\nbe alive in a disorganized state.\n24\n\"(2) HUMAN EMBRYO OR EMBRYOS.-The term\n25\n'human embryo or embryos' includes any organism,\nt S 30 ES\n5\n1\nnot protected as a human subject under part 46 of\n2\ntitle 45, Code of Federal Regulations, as of the date\n3\nof enactment of this section, that is derived by fer-\n4\ntilization, parthenogenesis, cloning, or any other\n5\nmeans from one or more human gametes or human\n6\ndiploid cells.\n7\n\"(3) RISK OF INJURY.-The term 'risk of in-\n8\njury' means subjecting a. human embryo or embryos\n9\nto risk of injury or death greater than that allowed\n10\nfor research on fetuses in utero under section\n11\n46.204(b) of title 45, Code of Federal Regulations,\n12\nand section 498(b) of this Act.\"\n13 SEC. 4. NATIONAL AMNIOTIC AND PLACENTAL STEM CELL\n14\nBANK.\n15\n(a) IN GENERAL.-The Secretary of Health and\n16 Human Services shall enter into a contract with the Insti-\n17 tute of Medicine for the conduct of a study to recommend\n18 an optimal structure for an amniotic and placental stem\n19 cell bank program and to address pertinent issues to maxi-\n20 mize the potential of such technology, including collection,\n21 storage, standards setting, information sharing, distribu-\n22 tion, reimbursement, research, and outcome measures. In\n23 conducting such study, the Institute should receive input\n24 from relevant experts including the existing operators of\ntS 30 ES\n6\n1 federal tissue bank programs and the biomedical research\n2 programs within the Department of Defense.\n3\n(b) REPORT.-Not later than 180 days after the date\n4 of enactment of this Act, the Institute of Medicine shall\n5 complete the study under subsection (a) and submit to the\n6 Secretary of Health and Human Services and the appro-\n7 priate committees of Congress a report on the results of\n8 such study.\nPassed the Senate April 11, 2007.\nAttest:\nSecretary.\n$ S 30 ES\nEXECUTIVE OFFICE OF THE PRESIDENT\nOFFICE OF MANAGEMENT AND BUDGET\nWASHINGTON, D.C. 20503\nApril 10, 2007\n(Senate)\nSTATEMENT OF ADMINISTRATION POLICY\nS. 30 - Hope Offered through Principled and Ethical Stem Cell Research Act\n(Sens. Coleman (R) MN and Isakson (R) GA)\nThe Administration strongly supports Senate passage of S. 30, a bill to support and intensify\nresearch into techniques of deriving pluripotent stem cells without harming or destroying human\nembryos.\nPluripotent stem cells are cells that can be differentiated into nearly all the cell types in the\nhuman body. At present, the means of obtaining such cells involve the destruction or\nendangerment of living human embryos, raising serious moral concerns. Ongoing research is\ninvestigating whether stem cells derived from the tissues of donors, umbilical cord blood,\namniotic fluid, placentas, and other non-embryonic sources may be pluripotent. Numerous\ntechniques are being explored by researchers, and significant scientific advances have been\nreported in the past few years.\nThis bill authorizes the Department of Health and Human Services to support the use and further\ndevelopment of techniques for producing pluripotent cells like those derived from human\nembryos, but without harming or destroying the embryos. Research using pluripotent stem cells\nis still at a very early stage, and it will be years before researchers know how much promise lies\nin therapeutic applications. This early stage is precisely when it is most important to develop\nethically responsible techniques, so that the potential of pluripotent stem cells can be explored\nwithout violating human dignity and life:\nThis bill also directs the Department, under contract with the Institute of Medicine, to study and\nrecommend the optimal structure for an amniotic and placental stem cell bank. While research\nin this area is still developing, recent publications suggest that a new and readily available source\nof pluripotent stem cells may exist in the amniotic fluid that cushions babies in the womb. The\nAdministration supports further investigation in this area.\nThe Administration does not believe science and ethics need be at odds. Scientists have shown\nthey have the ingenuity and skill to pursue the potential benefits of stem cell research without\nendangering nascent human life in the process. By seeking intensified support for non-\ndestructive alternatives, we believe we can advance medical research in valuable ways while\nrespecting ethical boundaries that are vital to millions of American taxpayers.\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nDraft\n[Draft]\n2\nN.D.\nP5;\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nTHE WHITE HOUSE\nOffice of the Press Secretary\n(Heiligendamm, Germany)\nFor Immediate Release\nJune 7, 2007\nSTATEMENT BY THE PRESIDENT\nToday, the United States House of Representatives, with its vote\non the embryonic stem cell bill, chose to discard existing\nprotections on human life. This bill puts scientific research\nand ethical principle into conflict, rather than supporting a\nbalanced approach that advances scientific and medical frontiers\nwithout violating moral principles.\nMy Administration has sought to understand the dilemmas of stem\ncell research not as a choice between science and ethics, but as\na challenge to advance medicine while meeting our solemn\nobligation to defend human life. That is why in 2001 I\nauthorized the first federal funding for research on embryonic\nstem cells, under careful safeguards. This policy encouraged\nethical research, while requiring taxpayer funds not be used to\nsupport the creation, destruction, or harming of living human\nembryos.\nRecent scientific developments have reinforced my conviction\nthat stem cell science can progress in ethical ways. Researchers\nhave been investigating innovative techniques that could allow\ndoctors and scientists to produce stem cells just as versatile\nas those derived from human embryos, but without harming life,\nand the House vote on this bill took place just after\nsignificant advances in stem cell research were reported in\nleading scientific journals. These reports give us added hope\nthat we may one day enjoy the potential benefits of embryonic\nstem cells without destroying human life.\nI am disappointed the leadership of Congress recycled an old\nbill that would simply overturn our country's carefully balanced\npolicy on embryonic stem cell research. If this bill were to\nbecome law, American taxpayers would for the first time in our\nhistory be compelled to support the deliberate destruction of\nhuman embryos. Crossing that line would be a grave mistake. For\nthat reason, I will veto the bill passed today.\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nEmail\nRE: Stem Cell Event - To: Karl Zinsmeister\n1\n06/14/2007\nP5;\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA],\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nEmail\nTuesday Meetings? - To: Karl Zinsmeister - From: Christopher Papagianis\n1\n06/18/2007\nP5;\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nHandwritten Note S.C. Principals' Mtg Notes\n2\n06/2007\nP5;\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nDraft\nFrame\n1\nN.D.\nP5;\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nEmail\nS.5 Veto Statement - To: John Marburger - From: Karl Zinsmeister\n1\n06/12/2007\nP5;\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nEmail\nRE: OSTP Comments to Veto Statement - To: Christopher Papagianis\n-\n1\n06/12/2007\nP5;\nFrom: Karl Zinsmeister\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs;and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nEmail\nRE: - To: Karl Zinsmeister - From: Kevin Sullivan\n1\n06/18/2007\nP5;\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal'office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nEmail\nRE: Stem Cell Qs - To: Karl Zinsmeister, et al. - From: Christopher\n1\n06/18/2007\nP5;\nPapagianis\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nEmail\nRE: Stem Cell Guidance - To: Karl Zinsmeister, et al. - From: John\n1\n06/18/2007\nP5;\nMarburger\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nEmail\nRE: Stem Cell Guidance - To: John Marburger, et al. - From: Karl\n3\n06/18/2007\nP5;\nZinsmeister\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRAJ\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nDraft\n[Draft]\n2\nN.D.\nP5;\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nPage 1 of 2\nZinsmeister, Karl\nFrom:\nPapagianis, Christopher C.\nSent:\nThursday, June 07, 2007 3:42 PM\nTo:\nZinsmeister, Karl; Troy, Tevi D.\nSubject: GOP Proposal to Boost Federal Support for Pluripotent Stem Cell Research\nHere is how the MTR was described in the House.\nFrom: GOP Leader Alert [mailto:[email protected]]\nSent: Thursday, June 07, 2007 1:16 PM\nSubject: GOP Proposal to Boost Federal Support for Pluripotent Stem Cell Research\nGOP PROPOSAL TO BOOST FEDERAL SUPPORT FOR PLURIPOTENT STEM\nCELL RESEARCH\nSUPPORT FOR RESEARCH THAT DOESN'T REQUIRE DESTROYING HUMAN LIFE\nJune 7, 2007\nToday House Republicans will offer a proposal to direct the National Institute of Health (NIH) to conduct and\nsupport research involving stem cells that have \"pluripotent\" or embryonic-like qualities without harming or\ndestroying an embryo. The proposal will be offered as a motion-to-recommit (MTR) on the Stem Cell Research\nEnhancement Act (S.5), a bill that would force taxpayers to foot the bill for the destruction of human life for\nresearch.\nThe U.S. Conference of Catholic Bishops delivered a letter to Congress stating that those who support S.5 would\n\"explore ways to achieve the benefits of stem cell research within moral limits, but only if they can also violate those\nlimits,\" which \"only underscores the underlying bill's cavalier attitude towards moral limits.\"\nThe Republican proposal, based on legislation authored by Reps. Roscoe Bartlett (R-MD) and Phil Gingrey (R-GA),\nremoves the provisions of S.5 that would force taxpayers to pay for the destruction of human life, leaving only the\nethical alternative stem cell research. This approach is bolstered by new research showing the full potential of stem\ncell research can be realized without destroying living human embryos that are capable of growing into healthy\nhuman adults. According to the Washington Post:\n\"Three teams of scientists said yesterday they had coaxed ordinary mouse skin cells\nto become what are effectively embryonic stem cells without creating or\ndestroying embryos in the process\n\"If the process also works with human cells, as scientists suspect it will with some\n6/8/2007\nPage 2 of 2\nmodifications, it would mean that a person's own skin cells could be converted directly\ninto stem cells without having to collect healthy human eggs or destroy human\nembryos -- steps that until now have been required to obtain embryonic stem cells.\n\"Those stem cells could then be used to make a wide variety of personalized\nreplacement tissues.\"\nAt a press conference today, House Republican Leader John Boehner (R-OH) reiterated his support for stem cell\nresearch that does not involve the destruction of human life:\n\"The question here is not whether you support stem cell research -- the question is\nwhether taxpayers should be forced to fund ethically-questionable research\nthat crosses the line. We should be focusing on research that shows promise, like\nadult stem cell research.\"\nRepublicans are urged to support the MTR.\nREPUBLICAN LEADER PRESS OFFICE\nREP. JOHN BOEHNER (R-OH)\nH-204, THE CAPITOL\n(202) 225-4000\nHTTP://REPUBLICANLEADER.HOUSE.GOV/\n6/8/2007\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nHandwritten Note [Notes]\n1\nN.D.\nP5;\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nDraft\nDraft Statement by the President\n2\n06/07/2007\nP5;\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F.\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nWithdrawal Marker\nThe George W. Bush, Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nEmail\nFOR REVIEW - Draft Statement on Passage of Stem Cell Bill - To: VP\n2\n06/06/2007\nP5;\nStaff Sec, et al. - From: Thomas Bowman\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\n-\nTell\nZor hours\n(100 keyl\nRegistry\nName Change\n-\nWithdrawal Marker\nThe George W. Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nEmail\nRe: Patients and Statement - To: Christopher Papagianis - From: Karl\n3\n06/06/2007\nP5;\nZinsmeister\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. 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Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. 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Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. 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Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. 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Bush Library\nFORM\nSUBJECT/TITLE\nPAGES\nDATE\nRESTRICTION(S)\nEmail\nRE: - To: Christopher Papagianis - From: Tevi Troy\n1\n06/06/2007\nP5;\nThis marker identifies the original location of the withdrawn item listed above.\nFor a complete list of items withdrawn from this folder, see the\nWithdrawal/Redaction Sheet at the front of the folder.\nCOLLECTION:\nDomestic Policy Council\nSERIES:\nZinsmeister, W. Karl - Subject Files\nFOLDER TITLE:\nStem Cells 2007: Stem Cell Veto 2007 and Executive Order [2]\nFRC ID:\nFOIA IDs and Segments:\n14303\n2017-0029-F\nOA Num.:\n14165\n2014-0503-F\nNARA Num.:\n14062\nRESTRICTION CODES\nPresidential Records Act - [44 U.S.C. 2204(a)]\nFreedom of Information Act - [5 U.S.C. 552(b)]\nP1 National Security Classified Information [(a)(1) of the PRA]\nb(1) National security classified information [(b)(1) of the FOIA]\nP2 Relating to the appointment to Federal office [(a)(2) of the PRA]\nb(2) Release would disclose internal personnel rules and practices of\nP3 Release would violate a Federal statute [(a)(3) of the PRA]\nan agency [(b)(2) of the FOIA]\nP4 Release would disclose trade secrets or confidential commercial or\nb(3) Release would violate a Federal statute [(b)(3) of the FOIA]\nfinancial information [(a)(4) of the PRA]\nb(4) Release would disclose trade secrets or confidential or financial\nP5 Release would disclose confidential advice between the President\ninformation [(b)(4) of the FOIA]\nand his advisors, or between such advisors [a)(5) of the PRA]\nb(6) Release would constitute a clearly unwarranted invasion of\nP6 Release would constitute a clearly unwarranted invasion of\npersonal privacy [(b)(6) of the FOIA]\npersonal privacy [(a)(6) of the PRA]\nb(7) Release would disclose information compiled for law enforcement\npurposes [(b)(7) of the FOIA]\nPRM. Personal record misfile defined in accordance with 44 U.S.C.\nb(8) Release would disclose information concerning the regulation of\n2201(3).\nfinancial institutions [(b)(8) of the FOIA]\nb(9) Release would disclose geological or geophysical information\nDeed of Gift Restrictions\nconcerning wells [(b)(9) of the FOIA]\nA. Closed by Executive Order 13526 governing access to national\nRecords Not Subject to FOIA\nsecurity information.\nB. Closed by statute or by the agency which originated the document.\nCourt Sealed - The document is withheld under a court seal and is not subject to\nC. Closed in accordance with restrictions contained in donor's deed\nthe Freedom of Information Act.\nof gift.\nThis Document was withdrawn on 5/30/2019 by erg\nSimple switch turns cells embryonic\nPage 1 of 3\nClose window\nX\[email protected]\nPrint this page\nThe best in science journalism\nNature\nPublished online: 6 June 2007; I :10.1038/447618a\nnature\nSimple switch turns cells embryonic\nTechnique removes need for eggs or embryos.\n7\nThought world take\nDavid Cyranoski\n10 yrs.\nResearch reported this week by three different groups shows that normal skin cells can be\nreprogrammed to an embryonic state in mice 1, 2, The race is now on to apply the\nsurprisingly straightforward procedure to human cells.\nIf researchers succeed, it will make it relatively easy to produce cells that seem\nindistinguishable from embryonic stem cells, and that are genetically matched to individual\npatients. There are limits to how useful and safe these would be for therapeutic use in the near\nterm, but they should quickly prove a boon in the lab.\nThe birth of this chimaeric mouse suggests that the cells used to generate it\nbehave like embryonic stem cells.\nS. OGDEN\n\"It would change the way we see things quite dramatically,\" says Alan Trounson of Monash\nUniversity in Victoria, Australia. Trounson wasn't involved in the new work but says he plans to\nstart using the technique \"tomorrow\". \"I can think of a dozen experiments right now - and\nthey're all good ones,\" he says.\nIn theory, embryonic stem cells can propagate themselves indefinitely and are able to become\nany type of cell in the body. But so far, the only way to obtain embryonic stem cells involves\ndestroying an embryo, and to get a genetic match for a patient would mean, in effect, cloning\nthat person - all of which raise difficult ethical questions.\nhttp://www.nature.com/news/2007/070604/pf/447618a_pf.html\n6/6/2007\nSimple switch turns cells embryonic\nPage 2 of 3\nAs well as having potential ethical difficulties, the 'cloning' procedure is technically difficult. It\ninvolves obtaining unfertilized eggs, replacing their genetic material with that from an adult\ncell and then forcing the cell to divide to create an early-stage embryo, from which the stem\ncells can be harvested. Those barriers may have now been broken down.\n\"Neither eggs nor embryos are necessary. I've never worked with either,\" says Shinya\nYamanaka of Kyoto University, who has pioneered the new technique.\nLast year, Yamanaka introduced a system that uses mouse fibroblasts, a common cell type\nthat can easily be harvested from skin, instead of eggs⁴. Four genes, which code for four\nspecific proteins known as transcription factors, are transferred into the cells using\nretroviruses. The proteins trigger the expression of other genes that lead the cells to become\npluripotent, meaning that they could potentially become any of the body's cells. Yamanaka\ncalls them induced pluripotent stem cells (iPS cells). \"It's easy. There's no trick, no magic,\"\nsays Yamanaka.\nIt's unbelievable, just\nThe results were met with amazement, along with a good dose of\namazing. It's like Dolly.\nscepticism. Four factors seemed too simple. And although the cells\nIt's that type of\nhad some characteristics of embryonic cells - they formed\naccomplishment.\ncolonies, could propagate continuously and could form cancerous\ngrowths called teratomas - they lacked others. Introduction of iPS\ncells into a developing embryo, for example, did not produce a 'chimaera' - a mouse carrying\na mix of DNA from both the original embryo and the iPS cells throughout its body. \"I was not\ncomfortable with the term 'pluripotent' last year,\" says Hans Schöler, a stem-cell specialist at\nthe Max Planck Institute for Molecular Biomedicine in Münster who is not involved with any of\nthe three articles.\nThis week, Yamanaka presents a second generation of iPS cells¹, which pass all these tests. In\naddition, a group led by Rudolf Jaenisch² at the Whitehead Institute for Biomedical Research in\nCambridge, Massachusetts, and a collaborative effort³ between Konrad Hochedlinger of the\nHarvard Stem Cell Institute and Kathrin Plath of the University of California, Los Angeles, used\nthe same four factors and got strikingly similar results.\n\"It's a relief as some people questioned our results, especially after the Hwang scandal,\" says\nYamanaka, referring to the irreproducible cloning work of Woo Suk Hwang, which turned out to\nbe fraudulent. Schöler agrees: \"Now we can be confident that this is something worth building\non.\"\nThe improvement over last year's results was simple. The four transcription factors used by\nYamanaka reprogramme cells inconsistently and inefficiently, so that less than 0.1% of the\nmillion cells in a simple skin biopsy will be fully reprogrammed. The difficulty is isolating those\nin which reprogramming has been successful. Researchers do this by inserting a gene for\nantibiotic resistance that is activated only when proteins characteristic of stem cells are\nexpressed. The cells can then be doused with antibiotics, killing off the failures.\nThe protein Yamanaka used as a marker for stem cells last year was not terribly good at\nidentifying reprogrammed cells. This time, all three groups used two other protein markers -\nNanog and Oct4 - to great effect. All three groups were able to produce chimaeric mice using\niPS cells isolated in this way; and the mice passed iPS DNA on to their offspring.\nJaenisch also used a special embryo to produce fetuses whose cells were derived entirely from\niPS cells. \"Only the best embryonic stem cells can do this,\" he says.\nhttp://www.nature.com/news/2007/070604/pf/447618a_pf.html\n6/6/2007\nSimple switch turns cells embryonic\nPage 3 of 3\n\"It's unbelievable, just amazing,\" says Schöler, who heard Jaenisch present his results at a\nmeeting on 31 May in Bavaria. \"For me it's like Dolly [the first cloned mammal]. It's that type\nof accomplishment.\"\nThe method is inviting. Whereas cloning with humans was limited by the number of available\neggs and by a tricky technique that takes some six months to master, Yamanaka's method can\nuse the most basic cells and can be accomplished with simple lab techniques.\nBut applying the method to human cells has yet to be successful. \"We are working very hard\n- day and night,\" says Yamanaka. It will probably require more transcription factors, he adds.\nIf it works, researchers could produce iPS cells from patients with conditions such as\nParkinson's disease or diabetes and observe the molecular changes in the cells as they\ndevelop. This 'disease in a dish' would offer the chance to see how different environmental\nfactors contribute to the condition, and to test the ability of drugs to check disease\nprogression.\nBut the iPS cells aren't perfect, and could not be used safely to make genetically matched cells\nfor transplant in, for example, spinal-cord injuries. Yamanaka found that one of the factors\nseems to contribute to cancer in 20% of his chimaeric mice. He thinks this can be fixed, but\nthe retroviruses used may themselves also cause mutations and cancer. \"This is really\ndangerous. We would never transplant these into a patient,\" says Jaenisch. In his view,\nresearch into embryonic stem cells made by cloning remains \"absolutely essential\".\nIf the past year is anything to judge by, change will come quickly. \"I'm not sure if it will be us,\nor Jaenisch, or someone else, but I expect some big success with humans in the next year,\"\nsays Yamanaka.\nAdditional reporting by Heidi Ledford\nFor more on alternative stem-cell work, see 'Stem cells: Recycling the abnormal';\nand see http://www.nature.com/stemcells\nArticle brought to you by: Nature\nTop\nReferences\n1. Okita, K., Ichisaka, T. & Yamanaka, S. Nature doi: 10.1038/nature05934 (2007).\n2. Wernig, M. et al. Nature doi: 10.1038/nature05944 (2007).\n3. Maherali, N. et al. Cell Stem Cell doi: 10.1016/j.stem.2007.05.014 (2007).\n4. Takahashi, K. & Yamanaka, S. Cell 126, 663-676\n(2006). I Article I PubMed I ChemPort I\nTop\nStory from [email protected]:\nhttp://news.nature.com//news/2007/070604/447618a.html\nnpg\n© 2006 Nature Publishing Group I Privacy policy\nhttp://www.nature.com/news/2007/070604/pf/447618a_pfhtm1\n6/6/2007"
}