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3054
The following is a brief statement of the
history of the various cases of necrosis of the jaw,
which have developed among employees of the United
States Radium Corporation, at its factories in Orange,
New Jersey:
Case I. - Miss M. M., employed from Octo-
ber 1, 1917, to January 25, 1922, developed a necrosis
of the jaw and later died.
Case II - Miss V. R., employed from Septem-
ber 23, 1918, to April 13, 1921, developed, following
the extraction of a tooth by Dr. W. F. B. of Newark, a
rapidly progressing necrosis of the jaw, not improved
by curetting eight or nine times. Miss R. finally died
as a result of this disease process.
Case III - Mrs. K., employed from 1917 to 1920
inclusive, developed, following the extraction of a tooth
about December, 1923, progressive necrosis of the jaw,
necessitating the removal of much of her left upper jaw
and two blood transfusions. This patient died of chronic
sepsis on December 9, 1924.
Case IV - Miss M. C., employed for a period of
six and one-half years ending December, 1923, began to
fail in health in 1920. Her symptoms were extreme fatigue
and weakness withpallor. She continued her work in spite
- 2 -
of increasing ill health and in October, 1923, developed
a toothache with local swelling of the face. On Decem-
ber 24, 1923, she had an upper and a lower right molar
pulled, a piece of decayed bone coming out with one of
these teeth. She then stopped work. Normal healing of
the jaw did not ensue; instead, a discharge of pus began
and persisted. Later, two other teeth at some distance
became affected and were extracted. When examined in
May, 1924, she had, in addition to the process in the
lower jaw, a new sinus in the upper jaw communicating
with the antrum, as shown by X-rays. Her appearance
was very bad; she had lost much weight and was very pale.
Her blood, on microscopical examination, showed a pro-
found anemia. She complained of pain in the bones of
her face, had considerable inconvenience from the dis-
charge of foul pus in her mouth and was forced to spend
much of her time in bed. She said, however, that of
late she had felt a little better -- a statement not
in accord with her appearance nor with the new septic
process. At the time of examination, this girl was in
an extremely serious condition.
X-ray films made May 7, 1924, showed necrosis
of the right upper maxilla with a great deal of clouding
- 3 -
of the antrum and an apparent tendency to extend into
the nose. The necrosis was not yet great enough to
cause loss of all the teeth, but the condition of the
antrum and the tendency of the process to extend up-
wards toward the skull made one fear the possible on-
set of meningitis.
Case V - Miss G. F., who left the employ
of the Radium Corporation in 1919, had a left lower
molar extracted in 1923. The wound apparently healed
normally. Six months later a sinus appeared at the
site of the extracted molar and drained pus profusely
for some months. X-rays taken at the Reconstruction
Hospital, New York City, on March 3, 1924, showed evi-
dence of a chronic infectious process in the jaw in the
region of the extracted tooth. This patient left the
hospital five days later unrelieved and with a diagnosis
ofechronic osteomyelitis of the Jaw, possibly due to
phosphorus poisoning. She was however, reported in
May, 1924, to have recovered satisfactorily.
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"ocrText": "3054\nThe following is a brief statement of the\nhistory of the various cases of necrosis of the jaw,\nwhich have developed among employees of the United\nStates Radium Corporation, at its factories in Orange,\nNew Jersey:\nCase I. - Miss M. M., employed from Octo-\nber 1, 1917, to January 25, 1922, developed a necrosis\nof the jaw and later died.\nCase II - Miss V. R., employed from Septem-\nber 23, 1918, to April 13, 1921, developed, following\nthe extraction of a tooth by Dr. W. F. B. of Newark, a\nrapidly progressing necrosis of the jaw, not improved\nby curetting eight or nine times. Miss R. finally died\nas a result of this disease process.\nCase III - Mrs. K., employed from 1917 to 1920\ninclusive, developed, following the extraction of a tooth\nabout December, 1923, progressive necrosis of the jaw,\nnecessitating the removal of much of her left upper jaw\nand two blood transfusions. This patient died of chronic\nsepsis on December 9, 1924.\nCase IV - Miss M. C., employed for a period of\nsix and one-half years ending December, 1923, began to\nfail in health in 1920. Her symptoms were extreme fatigue\nand weakness withpallor. She continued her work in spite\n- 2 -\nof increasing ill health and in October, 1923, developed\na toothache with local swelling of the face. On Decem-\nber 24, 1923, she had an upper and a lower right molar\npulled, a piece of decayed bone coming out with one of\nthese teeth. She then stopped work. Normal healing of\nthe jaw did not ensue; instead, a discharge of pus began\nand persisted. Later, two other teeth at some distance\nbecame affected and were extracted. When examined in\nMay, 1924, she had, in addition to the process in the\nlower jaw, a new sinus in the upper jaw communicating\nwith the antrum, as shown by X-rays. Her appearance\nwas very bad; she had lost much weight and was very pale.\nHer blood, on microscopical examination, showed a pro-\nfound anemia. She complained of pain in the bones of\nher face, had considerable inconvenience from the dis-\ncharge of foul pus in her mouth and was forced to spend\nmuch of her time in bed. She said, however, that of\nlate she had felt a little better -- a statement not\nin accord with her appearance nor with the new septic\nprocess. At the time of examination, this girl was in\nan extremely serious condition.\nX-ray films made May 7, 1924, showed necrosis\nof the right upper maxilla with a great deal of clouding\n- 3 -\nof the antrum and an apparent tendency to extend into\nthe nose. The necrosis was not yet great enough to\ncause loss of all the teeth, but the condition of the\nantrum and the tendency of the process to extend up-\nwards toward the skull made one fear the possible on-\nset of meningitis.\nCase V - Miss G. F., who left the employ\nof the Radium Corporation in 1919, had a left lower\nmolar extracted in 1923. The wound apparently healed\nnormally. Six months later a sinus appeared at the\nsite of the extracted molar and drained pus profusely\nfor some months. X-rays taken at the Reconstruction\nHospital, New York City, on March 3, 1924, showed evi-\ndence of a chronic infectious process in the jaw in the\nregion of the extracted tooth. This patient left the\nhospital five days later unrelieved and with a diagnosis\nofechronic osteomyelitis of the Jaw, possibly due to\nphosphorus poisoning. She was however, reported in\nMay, 1924, to have recovered satisfactorily."
}