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6.
Daily olimination of radium - urine- average
55 u ug
Total radium per day in excreta
363 10 11
Total radium in system, Subject B
13.5 ug
Coefficient of elimination 2.5 x 10"5 day
0.0025 % por
day
Time required to eliminate 1 ug about 2700 days
indicate
Discussion results establish the specific character
of the rate of elimination of radium which is fixed in the system. It
varies greatly for different persons, but in all cases the excretion
is a slow process. We refrain from generalizing for we feel that more
extended experiments must be conducted to ascertain what factors con-
trol the rate of elimination. Moreover, some radium is doubtless
renoved from the system in other ways. Traces of radium may be lost
in the perspiration and epithelial cells, in the menstral fluid, in
the milk during lactation, and the slight transfor of radium to the
offspring during prognaney thongh improbable, is not excluded.
Finally we wish to oall attention to two sources of
experimental error involved in deducing the rate of elimination
of radium. The constant assigned to the gamma ray instrument used
in all of these measurements probably requires some correction.
As we have stated (1) the constant is based upon a single calibration.
To obtaine a more accurate value for the constant of the WulfeHess
gamma ray instrument another method of calibrating this electroscope
was devised. An inactive living subject served as a medium on which
were fastened some 20 to 40 standard one microgram ampules of radium
solution. The ampules were distributed over the surface of the body,
but were more closely spaced in the regions of the larger bony masses.
The constant determined for the gamma ray instrument, the
electroscope previously used (1) by this method while of the same order
(1) See p. 347 Vol. 21, Yournal Roetgenology and Radium Therapy.
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"ocrText": "6.\nDaily olimination of radium - urine- average\n55 u ug\nTotal radium per day in excreta\n363 10 11\nTotal radium in system, Subject B\n13.5 ug\nCoefficient of elimination 2.5 x 10\"5 day\n0.0025 % por\nday\nTime required to eliminate 1 ug about 2700 days\nindicate\nDiscussion results establish the specific character\nof the rate of elimination of radium which is fixed in the system. It\nvaries greatly for different persons, but in all cases the excretion\nis a slow process. We refrain from generalizing for we feel that more\nextended experiments must be conducted to ascertain what factors con-\ntrol the rate of elimination. Moreover, some radium is doubtless\nrenoved from the system in other ways. Traces of radium may be lost\nin the perspiration and epithelial cells, in the menstral fluid, in\nthe milk during lactation, and the slight transfor of radium to the\noffspring during prognaney thongh improbable, is not excluded.\nFinally we wish to oall attention to two sources of\nexperimental error involved in deducing the rate of elimination\nof radium. The constant assigned to the gamma ray instrument used\nin all of these measurements probably requires some correction.\nAs we have stated (1) the constant is based upon a single calibration.\nTo obtaine a more accurate value for the constant of the WulfeHess\ngamma ray instrument another method of calibrating this electroscope\nwas devised. An inactive living subject served as a medium on which\nwere fastened some 20 to 40 standard one microgram ampules of radium\nsolution. The ampules were distributed over the surface of the body,\nbut were more closely spaced in the regions of the larger bony masses.\nThe constant determined for the gamma ray instrument, the\nelectroscope previously used (1) by this method while of the same order\n(1) See p. 347 Vol. 21, Yournal Roetgenology and Radium Therapy."
}