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NCMRR [National Center for Medical Rehabilitation Research] Oct 22-23 '92 - Bethesda
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NCMRR [National Center for Medical Rehabilitation Research] Oct 22-23 '92 - Bethesda
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The First Word Newsletter
A publication of The First United Methodist Church
626 College Avenue, Alva, Oklahoma 73717
580/327-2571
Parsonage: 327-1105
[email protected]; Pastor: [email protected]; website: www.alvafumc.com
BIG NEWS
- A Mid-Week Reminder -
May 16, 2012
THE ASCENSION
OF
CHRIST
ACTS 1:1-11
"Following Without Seeing"
"But you will receive power when the Holy Spirit has come upon you; and you will be
my witnesses in Jerusalem, in all Judea and Samaria, and to the ends of the earth."
When he had said this, as they were watching, he was lifted up, and a cloud took him
out of their sight. Act. 1:8-9.
Each year, on the Sunday before Pentecost, we celebrate Ascension Sunday.
As we look back to this scripture from Acts, Luke tells us of the last post-
resurrection experience Jesus had with the disciples. After telling the
disciples what they were to be about in his absence, Jesus ascends into the
heavens right before their very eyes. Jesus was trying to prepare them for
how to be disciples and ultimately how to be the church when he no longer
walked in their midst. What a time of soul-searching and faith-inventory for
the disciples. Can we really do this without him?
Essentially, we ask ourselves the same kinds of questions. How do we
remain disciples of one we do not see? How do we follow someone that we
can't see leading us? Are we just on our own to fend for ourselves? These are
some of the questions we'll explore this Ascension Sunday as we conclude
the sermon series, "Where do we go from the empty tomb?" Sunday's topic
will be Following Without Seeing. I do hope you'll plan to be in church to
join your family in worshiping our ever-loving God. It is good to gather
together as God's people! And be sure to tell your kids, grandkids, neighbors
and everyone else about Vacation Bible School beginning this Sunday
evening. It's going to be great!!!
Please pray for peace.
Shalom,
Tay
STANDARD
JOIN THE FUN ON
PROMISE ISLAND!
at First United Methodist Church of Alva
Sunday, May 20-Thusday, May 24
5:30 - 8:00 p.m.
for children age 4 through 5ᵗʰ grade
family meal served Monday through Thursday at 5:30 p.m.
ATTENDANCE SUNDAY, MAY 13, 2012
Worship Service 205; Sunday School 83
May Events at First Church-
Sunday, May 20 - Confirmation Class 9:30 am
Piano Recital by Alycen Yoder's students 1-4 pm
Vacation Bible School, "Adventures on Promise Island," 5:30-8 pm for all
children age 4 through 5ᵗʰ grade
Monday through Thursday, May 21-24 - VBS with dinner 5:30 pm
Thursday, May 24- - Methodist Men have Service at Beadles 6:15 pm
Sunday, May 27 - Confirmation Sunday
Guest speaker John Eisenberg, missionary to Paraguay
Annual Conference, Tulsa's Boston Avenue UMC; ends Wednesday
Amanda Lynn Lunderville and David Joseph Molby
together with their parents
Bonnie & Todd Bothwell and Marvina Rae
request the honor of your presence
as they exchange wedding vows
on Saturday, May 26th, 2012
at 2:00 p.m.
First United Methodist Church
626 College Ave., Alva, OK 73717
Reception to follow
CONGRATULATIONS
to our 2012 GRADUATES
Alva High School, Saturday, May 19
Kolby Deitz
Colton Foote
Garrett Lahr
Blake Lehl
Dylan Manning
Aéropostale
Brooke Nation
Rylie Swanson
Ardmore High School,
Friday, May 25
Marek Payton Stein
(Jim & Diana Stein's son)
Decatur, Arkansas High School, Friday, May 11
Malissa Corr (Paul & Deb Corr's granddaughter)
May Birthdays
17-Randy Hamilton, Drue Washburn
19-Jodi Ann Ackerman, Lisa Franz
20-Karin Brown, Margaret Keeney, Danielle Williams
21-Micah Reiman, Cory Washburn, Hannah Malzahn
22-Janice Beran, Ali Kelly, Caylie Gallon, Sheila Short
23-Nicole Towns, Adam Holder
24-Shawn Lehr, James Bowen, Gracie Reiman
25-Shawn Decker, Gary Murrow, Stephen Davis, Marcus Heald
26-Christofer Kramp, Parker Bricklyn Grimsley (2 years old!)
27-Audrey Presnall, Jacob Ellis, Brand Rackley, Tatum Cresswell,
Reece Ann McMurphy (1 year old!)
28-Bob Case, Linda Pfleider, Wayne Kinzie, Rita Wilcoxson, Bailey Gentry,
Loni Staats, Jodie Boyd, Ethan Swanson, Brickman Bradt, McCelvie Herrington
30-Whitney Bowen, Joe Brown, Ira Dale Campbell, Amy Ryerson
31-Kristi Borth, Chance TeLinde
THE FIRST UNITED METHODIST CHURCH
626 COLLEGE AVE, ALVA, OK 73717
www.alvafumc.com youth: www.umyalva.weebly.com
Rev. Terry N Martindale, Pastor
Phone 580/327-2571; Parsonage 580/327-1105; Terry's cell: 405-919-5205
Church new e-mail: [email protected]; Pastor's e-mail: [email protected]
Bishop
Robert E Hayes
Editor/Secretary
Judy Throckmorton
District Superintendent
David Burris
Director of Youth
Christi Vickers
Director of Music
Irene Messoloras
Nursery Paige Chandler, Darbi Hinde
Organist
Alycen Yoder
Custodian
Lewis Wilt
Pianist
Joan Fisher
Sanctuary Custodian
Kate Nickel
RETURN SERVICE REQUESTED
Alva, OK 73717
626 College Ave.
First United Methodist Church
PERMIT NO. 9
ALVA, OK
PAID
U.S. POSTAGE
NON-PROFIT ORG.
NOTES FROM FRED
Some 45 years ago, Lex Frieden, Jim Shepherd, Jim Highful, Alan
Corr, all high school seniors, sang in our choir every Sunday. Those
four, as well as others, would come to my house once in a while on
Saturday night and play Tripoli, a card table game. While doing this
through the winter months, we all agreed to go to Acapulco the next
summer. Well, that fall, in November, Lex Frieden was in a car
accident in a convertible. It turned on its side and Lex, as well as other
OSU students, fell out. All got up except Lex. The back of his neck hit
an overhead bar and smashed his number five vertebrae. He is the only
one who got hurt, and he was totally paralyzed from his neck down.
We all decided to go visit him at St. Anthony Hospital in Oklahoma
City one cold January night. On the top floor of the hospital, we all
played Tripoli, and we all agreed that we were still going to go to
Acapulco-even Lex, flat on his back with his head hooked up to a
weighted harness. On the way home we all agreed that no way would
we go to Acapulco. Lex, not being an ordinary person, insisted, and we
all did go to Acapulco.
The hardship of a paraplegic in a wheel chair was something else. I
could write many stories of how we managed the trip. When we got
back from Acapulco, the seed for the idea of all the ramps, wide doors
to the public and hotel restrooms, elevators like our church has and
they have at our University, was planted. The ideal originally came
from Lex, and spread all over the United States and led to the
Americans with Disabilities Act and all the changes in making the
United States accessible to people with disabilities. Lex wound up
getting things done at the White House with Presidents Ronald Regan
and George Bush. Forty-five years ago, things all over the U.S. began
to change for wheelchair people. At Tulsa University, students would
lift Lex up and down all the stairs. One class that he was in was moved
from the upper floors down to the ground level for Lex. He began to
campaign for change, and spoke in the U.S. and internationally, all
over the world. One summer he was sent to Communist China to
consult with one of their highest officials regarding the man's son who
had broken his neck diving into a swimming pool. In 1967, Jim
Holder, Jim Highfill, Bob Reneau, Alan Corr, Bobby Wilson, and I
were invited and flew to Washington, D.C. for a big-time dinner party
in the Library of Congress for Lex Frieden. He received an award and
a check for $50,000. In his acceptance speech, Lex honored us from
Oklahoma, and mentioned how we influenced his life.
I visited him where he now lives in Houston. In his office I saw that
all the walls are covered with plaques and awards, and glass showcases
are full of really nice engraved honors and dates on crystal for his
ADA work. Lex has taught and still works and teaches in the medical
field at the University of Houston.
What got me started on all this is that he recently called to tell me
about a story that Fox Television in Houston ran about his life. The
film starts with Lex as an Eagle Scout, Valedictorian, and many years
later AHS Commencement speaker. The video can be seen on the
internet. Judy showed it to me on our church computer, and I'm trying
to get a DVD copy. If you want to see it, call Judy and she will
forward the link to you. I could write a couple more pages of my times
with Lex Frieden. Again, it all started right here in our church!
COLLEGE GRADUATES
Northwestern Oklahoma State University, Saturday, May 5
Summa Cum Laude: Wade Schwerdtfeger, BS Biology
Magna Cum Laude: Joseph Martin, BS Biology
Kyle Murrow, Bachelor of Science Agriculture
Lexie Cooper, BS (Charles & Lola Heaton's granddaughter)
Karmen Almgren Andrews, Bachelor of Social Work
Marcus Mead, Master of Education
Kaylyn Hansen, Master of Education
University of Central Oklahoma, Saturday, May 5
Allison Paige Rathgeber, Bachelor of Arts Public Relations
Oklahoma City University, Saturday, May 5
Andrew Holder, BA Mass Communications, Public Relations & Broadcasting
Oklahoma State University, Saturday, May 5
Matthew Sutter, BS Business Administration & Finance
Blair Sutter, BS Political Science (accepted to OU Law School)
University of Oklahoma
Tom Bishop, BS Aviation (Karen & Byron Koehn's nephew)
University of Tulsa
Elliott Ridgway, BS Computer Science (Alycen Yoder's grandson)
Truman State University
Tanner McMillin, BS Justice Systems (Alycen Yoder's grandson)
Hayes College
Miriam Watts, Bachelor of Science (Rose Elmore's granddaughter)
Baker University
Sarah Watts, Master of Education Admin. (Rose Elmore's granddaughter)
In Our Prayers CHILDREN'S HOSP., OKC: Skyler Molby (had surgery
Wednesday). LITTLE ROCK: Betty Jo Pangburn. BASS HOSPITAL ICU,
ENID: Margaret Keeney (had by-pass surgery Tuesday).
McBRIDE, OKC: Don Waters. CALUMET: C.J. Hansen. JUPITER, FL: David
Perfect. PORT ST. LUCIE, FL: Carmen Pittinaro. PORTLAND: Ray Paris.
ARLINGTON, KS: Ron Borth. HOUSTON: Darrell McKenzie.
PITTSBURGH: Betty Cooley, Kathryn Miller, Betty McSurdy, Jean Angotti.
DAYTON: John & Sis Cooley, Cindy Cooley. EDMOND: Margery Shorter.
THE COMMONS: Hazel White. BEADLES HOME: Joretta Buckles, Lynn
Hoskins. SHARE HOME: Joan Fisher, Dorothy Meisenheimer, Bud Nichols, Edith
Tate, Heather Kline, Mary Williams, Letha Hull. HOMESTEAD: Virginia Hubbard,
Doris Blue, Clara Tiberghein. HOME/CONTINUING CONCERN: Bradley Gilbert,
Max Benningfield, Barbara Rockenbach, Frances Kirkham, Mildred Johnson, Keri
Kalka, Ruby Nelson. AFGHANISTAN: Steve Ford. IRAQ: Wes Layton.
We Sympathize with Melissa & Trent Heaton and family in the death of
Melissa's brother, Mark Rennie, of Ponca City. He died Saturday, May 12,
as the result of a tragic fall; funeral is Saturday, May 19, 3 p.m., at Odd
Fellows Cemetery, Ponca City.
Altar Flowers Sunday are a memorial to Lyle Washburn by Carol Lee
Washburn and family.
Sunday's Radio Broadcast is sponsored by Lee & Peggy Mackey. Our
morning service airs Sundays at 9:45 a.m., on KALV.
Sunday's Liturgist, Children's Time, Ushers: United Methodist Youth
Sept. 9, 2011
Mr. Frieden,
In April I called
son making his first trip
you in regard for my
paralyzed. This is to Thank
in the 8 years after he was
you for phoning me back,
after you got my message. was
Roxanne's Cyour secretary)
Especially helpful
(within a few days) phoning
my daughter in - law, melroke
in CA
the family made it
to our Hrandson's Basic
training graduation at
Sen antonio. Then They
came here to Kingwood
(Westminster Home) to fe
with us.
I. can't tell you what
an important time it was
for our family.
Please know that
we are gratiful for your
help & in consagement.
Lois I Jem Millu
P.S. you may know of
someone who needs a place
such as on Westminstu
Home - uniquely independent
living with lissested Lurny
andilable: -a wonderful place.
ASBURY
SOUTH VAN PELT STREET
Dear Lex - 408 /
HILADELPHIA, PENNSYLVANIA 19146
Good Grief- 2 mne professiships in addition all
to all centruce to do nationally - - Hope there
latest is soing appointments. with wishs
well, you and Congratulatives antimed on best
lonky
HUMAN SERVICES
HEALTH
DEPARTMENT OF HEALTH & HUMAN SERVICES
Public Health Service
5
DEPARTMENT
National Institutes of Health
Bethesda, Maryland 20892
Room 450W, EPS
NCMRR, NICHD
6120 Executive Blvd.
Rockville, Maryland 20852
(301) 402-2242
FAX (301) 496-8678
May 28, 1992
Mr. Lex Frieden
Senior Vice President
TIRR (The Institute for Rehabilitation Research)
1333 Moursund
Houston, Texas 77030
Dear Lex:
Thank you for the time and effort you devoted to all the activities that took place in year one of the
National Advisory Board on Medical Rehabilitation Research. The enclosed Report and Plan for
Medical Rehabilitation Research reflects your leadership. You have a talent for bringing
together people with disparate points of view. Everyone has the right to feel that they contributed
to this document. This unity is directly attributable to your leadership. The presentation that you
and Dr. Cole made to the Advisory Board made a very positive impression on those who have
responsibility for funding grant applications. The field hearings were beneficial to the better
understanding of the need for medical rehabilitation research. The Texas field hearing was
especially well organized and the testimony was cogent.
I look forward to working with you in developing new directions for the Board.
Dincerely,
Sincerely,
David B. Gray, Ph.D.
Acting Deputy Director
Enclosure
THE NATIONAL CENTER FOR MEDICAL REHABILITATION RESEARCH
ADVISORY BOARD
Advisory Board Members
Peter W. Axelson, M.S., M.E.
Suzann K. Campbell, Ph.D., P.T.
Executive Director of Research
Professor
and Development
Department of Physical Therapy
Beneficial Design Inc.
College of Associated Health Professions
5858 Empire Grade
The University of Illinois at Chicago
Santa Cruz, California 95060
1919 W. Taylor Street, M/C 898
(408) 429-8447
Chicago, Illinois 60612
(408) 423-8450 FAX
(312) 996-1502
(312) 996-3807 FAX
Carolyn M. Baum, M.A., O.T.R.,
F.A.O.T.A.
Edmund Yee-Su Chao, Ph.D.
Elias Michael Director and Assistant Professor
Director
in Occupational Therapy and Neurology
Orthopedic Biomechanics Laboratory
Washington University School of Medicine
Mayo Clinic
Program in Occupational Therapy
200 First Street, S.W.
4567 Scott Avenue - Internal Box 8066
Rochester, Minnesota 55905
St. Louis, Missouri 63110
(507) 284-2588
(314) 362-6911
(507) 284-5392 FAX
(314) 362-0182 FAX
Theodore Cole, M.D.
Carol Bennett, M.D.
Professor
Chief of Urology
Department of Physical Medicine and
Rancho Los Amigos Medical Center
Rehabilitation
7601 East Imperial Highway HB 132
University of Michigan Hospitals
Downey, California 90242
University of Michigan
(310) 940-7437
1500 E. Medical Center Drive
(310) 940-7576 FAX
Ann Arbor, Michigan 48109-0042
(313) 936-7190
Henry Betts, M.D.
(313) 936-6121 FAX
Medical Director and Chief Executive Officer
Rehabilitation Institute of Chicago
Robert E. Cooke, M.D.
Room 1573
Professor Emeritus of Pediatrics
345 East Superior Street
State University of New York
Chicago, Illinois 60611
at Buffalo
(312) 908-6017
Director Emeritus
(312) 908-4300 FAX
Robert Warner Rehabilitation Center
865 Painted Bunting Lane
John H. Bowker, M.D.
Vero Beach, Florida 32963
Professor
(407) 234-1707
Department of Orthopaedics
and Rehabilitation
Lex Frieden
University of Miami
Senior Vice President
School of Medicine
TIRR
P.O. Box 016960 (D-27)
Baylor College of Medicine
Miami, Florida 33101
1333 Moursund
(305) 585-6371
Houston, Texas 77030
(305) 324-7658 FAX
(713) 797-5283
(713) 799-7095 FAX
Dorothy L. Gordon, D.N.Sc., R.N., F.A.A.N
Roberta B. Trieschmann, Ph.D.
Associate Dean of Graduate Affairs
Consulting Psychologist
The Johns Hopkins University
President RBT Association, Inc.
School of Nursing
P.O. Box 5566
600 North Wolfe Street
Scottsdale, Arizona 85261
Baltimore, MD 21205
(602) 998-5844
(410) 955-7758
(602) 998-5840 FAX
(410) 955-0466 FAX
George A. Zitnay, Ph.D.
Carl Granger, M.D.
President/CEO
Professor of Rehabilitation Medicine
National Head Injury Foundation, Inc.
State University of New York
1776 Massachusetts Avenue, N.W.
82 Farber Hallm, South Campus
Suite 100
Buffalo, NY 14214
Washington, D.C. 20036
(716) 829-2076
(202) 296-8850
(716) 829-2080 FAX
(202) 296-8850 FAX
Judith Heumann M.P.H.
Vice President
National and International Affairs
Ex-Officio Members
World Institute on Disability
510 16th Street - Suite 100
Duane Alexander, M.D.
Oakland, California 94612
Director
(510) 763-4100
National Institute of Child Health
(510) 763-4109 FAX
and Human Development
National Institutes of Health
Rebecca Ogle
Room2A04, Building 31
Adult Program Coordinator
9000 Rockville Pike
Spina Bifida Association of America
Bethesda, Maryland 20892
4590 MacArthur Boulevard, N.W.
(301) 496-3454
Suite 250
(301) 402-1104 FAX
Washington, D.C. 20007
(202) 944-3285
Praxedes Belandres, M.D.
(202) 944-3295 FAX
Physical Medicine Department
Walter Reed Army Medical Center
Herbert Schaumburg, M.D.
Department of Defense
Chairman of Neurology
6900 Georgia Avenue
Albert Einstein College of Medicine
Washington, D.C. 20307
1300 Morris Park Avenue
(202) 576-1368
Bronx, New York 10461
(202) 576-2478 FAX
(212) 430-3166
(212) 931-2476 FAX
Larry Burt
Manager
Peter W. Thomas, Esq.
Disability Prevention Program
General Council
Center for Disease Control
White, Verville, Fulton and Saner
4770 Buford Highway
Suite 1100
F29
1156 15th Street, N.W.
Atlanta, Georgia 30341
Washington, D.C. 20005
(404) 488-7080
(202) 659-2900
(404) 488-7075 FAX
(202) 659-2909 FAX
Nell Carney
Peter Frommer, M.D.
Commissioner
Deputy Director
Rehabilitation Services
National Heart, Lung and Blood
Administration
Institute
Office of Special Education and
National Institutes of Health
Rehabilitative Services
Building 31, 5A49
U.S. Department of Education
9000 Rockville Pike
Room 3028, M.E. Switzer Building
Bethesda, MD 20892
330 "C" Street
(301) 496-1078
Washington, D.C. 20202
(301) 402-0299 FAX
(202) 732-1331
(202) 732-1372 FAX
John Goldschmidt, M.D.
Director
James Cooper, M.D.
Rehabilitation R&D Services (117A)
Director
Department of Veteran Affairs
Cardiovascular Section
810 Vermont Avenue N.W.
National Insitute on Aging
Washington, D.C. 20420
Gateway Building, Room 3E327
(202) 535-7278
Bethesda, MD 20892
(202) 535-7497 FAX
(301) 496-6761
(301) 402-1784 FAX
Murray Goldstein, D.O.M.P.H.
Director
Judith A. Cooper, Ph.D.
National Institute of Neurological
National Institute on Deafness and
Disorders and Stroke
Other Communication Disorders
Building 31A, Room 8A52
National Institute of Health
9000 Rockville Pike
EPS, 400B
National Institute of Health
6120 Executive Boulevard
Bethesda, MD 20892
Rockville, MD 20892
(301) 496-9746
(301) 496-5061
(301) 496-0296 FAX
(301) 402-6251 FAX
Patricia A. Grady, Ph.D.
Timothy R. Dillingham, M.D.
Assistant Director
Director of Research for Physical Medicine
National Institute of Neurological
Walter Reed Army Medical Center
Disorders and Stroke
6900 Georgia Avenue, N.W.
National Institutes of Health
Washington, D.C. 20307
Bldg. 31, Room 8A52
(202) 576-1368
Bethesda, Maryland 20892
(202) 576-2478 FAX
(301) 496-3167
(301) 496-0296 FAX
Leslie Ford, M.D.
Chief
William H. Graves, Ed.D.
Community Oncology
Director
and Rehabilitation Branch
National Institute on Disability and
National Cancer Institute
Rehabilitation Research
EPN, Room 300 D
Office of Special Education and
Rockville, MD 20852
Rehabilitative Services
(301) 496-8541
U.S. Department of Education
(301) 496-8667 FAX
400 Maryland Avenue, S.W.
Washington, D.C. 20202-2572
(202) 205-8134
(202) 205-8997 FAX
Ada Sue Hinshaw Ph.D. RN
James B. Snow Jr., M.D.
Director
Director
National Center for Nursing Research
National Institue on Deafness and
National Institutes of Health
Other Communication Disorders
Room 5B03, Building 31
National Institute of Health
9000 Rockville Pike
Bethesda, MD 20892
Bethesda Maryland 20892
(301) 496-6595
(301) 496-8230
(301) 402-1590 FAX
(301) 480-4969 FAX
Pamela Starke-Reed, Ph.D.
Laura James, Ph.D. RN
Director
Nurse Scientist Administrator
Physical Functioning and Performance Section
National Center for Nursing Research
National Insitute on Aging
National Institutes of Health
Gateway Building, Room 3E327
Room 754, Westwood Bldg.
Bethesda, MD 20892
5333 Westbard Avenue
(301) 496-6761
Bethesda, MD 20816
(301) 402-1748 FAX
(301) 402-3290
(301) 402-2402 FAX
Dov Jaron, Ph.D.
Director
Biological and Critical Systems Division
National Science Foundation
1800 "G" Street, N.W.
Room 1132
Washington, D.C. 20550
(202) 357-9545
(202) 357-9803 FAX
Katherine D. Seelman, Ph.D.
National Council on Disability
800 Independence Avenue, S.W.
Suite 814
Washington, D.C. 20591
(202) 267-3846
(202) 453-4240 FAX
Lawrence E. Shulman, M.D.
Director
National Insitute of Arthritis and
Musculoskeletal and Skin
Diseases
National Institute of Health
9000 Rockville Pike
Room 4C32, Bldg. 31
Bethesda, MD 20892
(301) 496-4353
(301) 480-6069 FAX
THE NATIONAL CENTER FOR MEDICAL REHABILITATION RESEARCH
ADVISORY BOARD
Advisory Board Members
Peter W. Axelson, M.S., M.E.
Suzann K. Campbell, Ph.D., P.T.
Executive Director of Research
Professor
and Development
Department of Physical Therapy
Beneficial Design Inc.
College of Associated Health Professions
5858 Empire Grade
The University of Illinois at Chicago
Santa Cruz, California 95060
1919 W. Taylor Street, M/C 898
(408) 429-8447
Chicago, Illinois 60612
(408) 423-8450 FAX
(312) 996-1502
(312) 996-3807 FAX
Carolyn M. Baum, M.A., O.T.R.,
F.A.O.T.A.
Edmund Yee-Su Chao, Ph.D.
Elias Michael Director and Assistant Professor
Director
in Occupational Therapy and Neurology
Orthopedic Biomechanics Laboratory
Washington University School of Medicine
Mayo Clinic
Program in Occupational Therapy
200 First Street, S.W.
4567 Scott Avenue - Internal Box 8066
Rochester, Minnesota 55905
St. Louis, Missouri 63110
(507) 284-2588
(314) 362-6911
(507) 284-5392 FAX
(314) 362-9862 FAX
Theodore Cole, M.D.
Carol Bennett, M.D.
Professor
Chief of Urology
Department of Physical Medicine and
Rancho Los Amigos Medical Center
Rehabilitation
7601 East Imperial Highway HB 132
University of Michigan Hospitals
Downey, California 90242
University of Michigan
(213) 940-7437
1500 E. Medical Center Drive
(213) 843-6145 FAX
Ann Arbor, Michigan 48109-0042
(513) 936-7190
Henry Betts, M.D.
(513) 936-6121 FAX
Medical Director and Chief Executive Officer
Rehabilitation Institute of Chicago
Robert E. Cooke, M.D.
Room 1573
Professor Emeritus of Pediatrics
345 East Superior Street
State University of New York
Chicago, Illinois 60611
at Buffalo
(312) 908-6017
Director Emeritus
(312) 908-4300 FAX
Robert Warner Rehabilitation Center
865 Painted Bunting Lane
John H. Bowker, M.D.
Vero Beach, Florida 32963
Professor
(407) 234-1707
Department of Orthopaedics
and Rehabilitation
Lex Frieden
University of Miami
Senior Vice President
School of Medicine
TIRR
P.O. Box 016960 (D-27)
Baylor College of Medicine
Miami, Florida 33101
1333 Moursund
(305) 585-6371
Houston, Texas 77030
(305) 324-7658 FAX
(713) 797-5283
(713) 799-7095 FAX
Dorothy L. Gordon, D.N.Sc., R.N., F.A.A.N
Roberta B. Trieschmann, Ph.D.
Associate Dean of Graduate Affairs
Consulting Psychologist
The Johns Hopkins University
President RBT Association, Inc.
School of Nursing
P.O. Box 5566
600 North Wolfe Street
Scottsdale, Arizona 85261
Baltimore, MD 21205
(602) 998-5844
(410) 955-7758
(602) 998-5840 FAX
(410) 955-0466 FAX
George A. Zitnay, Ph.D.
Carl Granger, M.D.
President/CEO
Professor of Rehabilitation Medicine
National Head Injury Foundation, Inc.
State University of New York
1776 Massachusetts Avenue, N.W.
82 Farber Hallm, South Campus
Suite 100
Buffalo, NY 14214
Washington, D.C. 20036
(716) 831-2076
(202) 296-8850
(716) 831-2080 FAX
(202) 296-8850 FAX
Judith Heumann M.P.H.
Vice President
National and International Affairs
Ex-Officio Members
World Institute on Disability
510 16th Street - Suite 100
Duane Alexander, M.D.
Oakland, California 94612
Director
(510) 763-4100
National Institute of Child Health
(510) 763-4109 FAX
and Human Development
National Institutes of Health
Rebecca Ogle
Room2A04, Building 31
Adult Program Coordinator
9000 Rockville Pike
Spina Bifida Association of America
Bethesda, Maryland 20892
4590 MacArthur Boulevard, N.W.
(301) 496-3454
Suite 250
(301) 402-1104 FAX
Washington, D.C. 20007
(202) 944-3285
Praxedes Belandres, M.D.
(202) 994-3295 FAX
Physical Medicine Department
Walter Reed Army Medical Center
Herbert Schaumberg, M.D.
Department of Defense
Chairman of Neurology
6900 Georgia Avenue
Albert Einstein College of Medicine
Washington, D.C. 20307
1300 Morris Park Avenue
(202) 576-1368
Bronx, New York 10461
(202) 576-2478 FAX
(212) 430-3166
(212) 931-2476 FAX
Larry Burt
Manager
Peter W. Thomas, Esq.
Disability Prevention Program
General Council
Center for Disease Control
White, Verville, Fulton and Saner
4770 Buford Highway
Suite 1100
F29
1156 15th Street, N.W.
Atlanta, Georgia 30341
Washington, D.C. 20005
(404) 488-7080
(202) 659-2900
(404) 488-7075 FAX
(202) 659-2909 FAX
Nell Carney
Peter Frommer, M.D.
Commissioner
Deputy Director
Rehabilitation Services
National Heart, Lung and Blood
Administration
Institute
Office of Special Education and
National Institutes of Health
Rehabilitative Services
Building 31, 5A49
U.S. Department of Education
9000 Rockville Pike
Room 3028, M.E. Switzer Building
Bethesda, MD 20892
330 "C" Street
(301) 496-1078
Washington, D.C. 20202
(301) 402-0299 FAX
(202) 732-1331
(202) 732-1372 FAX
John Goldschmidt, M.D.
Director
James Cooper, M.D.
Rehabilitation R&D Services (117A)
Director
Department of Veteran Affairs
Cardiovascular Section
810 Vermont Avenue N.W.
National Insitute on Aging
Washington, D.C. 20420
Gateway Building, Room 3E327
(202) 535-7278
Bethesda, MD 20892
(202) 535-7497 FAX
(301) 496-6761
(301) 402-1784 FAX
Murray Goldstein, D.O.M.P.H.
Director
Judith A. Cooper, Ph.D.
National Institute of Neurological
National Institute on Deafness and
Disorders and Stroke
Other Communication Disorders
Building 31A, Room 8A52
National Institute of Health
9000 Rockville Pike
EPS, 400B
National Institute of Health
6120 Executive Boulevard
Bethesda, MD 20892
Rockville, MD 20892
(301) 496-9746
(301) 496-5061
(301) 496-0296 FAX
(301) 402-6251 FAX
Patricia A. Grady, Ph.D.
Timothy R. Dillingham, M.D.
Assistant Director
Director of Research for Physical Medicine
National Institute of Neurological
Walter Reed Army Medical Center
Disorders and Stroke
6900 Georgia Avenue, N.W.
National Institutes of Health
Washington, D.C. 20307
Bldg. 31, Room 8A52
(202) 576-1368
Bethesda, Maryland 20892
(202) 576-2478 FAX
(301) 496-3167
(301) 496-0296 FAX
Leslie Ford, M.D.
Chief
William H. Graves, Ed.D.
Community Oncology
Director
and Rehabilitation Branch
National Institute on Disability and
National Cancer Institute
Rehabilitation Research
EPN, Room 300 D
Office of Special Education and
Rockville, MD 20852
Rehabilitative Services
(301) 496-8541
U.S. Department of Education
(301) 496-8667 FAX
400 Maryland Avenue, S.W.
Washington, D.C. 20202-2572
(202) 205-8134
(202) 205-8997 FAX
Dov Jaron, Ph.D.
Director
Biological and Critical Systems Division
National Science Foundation
1800 "G" Street, N.W.
Room 1132
Washington, D.C. 20550
(202) 357-9545
(202) 357-9803 FAX
Katherine D. Seelman, Ph.D.
National Council on Disability
800 Independence Avenue, S.W.
Suite 814
Washington, D.C. 20591
(202) 267-3846
(202) 453-4240-FAX
Lawrence E. Shulman, M.D.
Director
National Insitute of Arthritis and
Musculoskeletal and Skin
Diseases
National Institute of Health
9000 Rockville Pike
Room 4C32, Bldg. 31
Bethesda, MD 20892
(301) 496-4353
(301) 480-6069 FAX
James B. Snow Jr., M.D.
Director
National Institue on Deafness and
Other Communication Disorders
National Institute of Health
Bethesda, MD 20892
(301) 496-6595
(301) 402-1590 FAX
Pamela Starke-Reed, Ph.D.
Director
Physical Functioning and Performance Section
National Insitute on Aging
Gateway Building, Room 3E327
Bethesda, MD 20892
(301) 496-6761
(301) 402-1748 FAX
Butler Heads
COLLEGE
OF
AAMC Committee
BAYLOR
<<<<<<<<<<<<<
MEDICINE
Baylor President Dr. William
SERVICE
T. Butler was appointed by the
BAYLOR
Association of American Medi-
cal Colleges to chair its adviso-
ry committee for Project
3000 x 2000.
The goal of this AAMC
MEDICINE
project is to increase to 3,000
NOVEMBER 1991
the number of underrepresent-
BAYLOR COLLEGE OF MEDICINE
ONE BAYLOR PLAZA, HOUSTON, TEXAS 77030
VOL. XXII, NO. 10
ed minority medical students
by the year 2000.
AIDS Research Center Organized
Frieden Chairing
Basic science and clinical researchers will join forces against 'this catastrophic disease, Shearer says.
Advisory Board
With nearly $10 million in
an outpatient facility for
Lex Frieden was elected
funding for both basic scientific
HIV/AIDS patients.
Z
chairman of the National Cen-
studies and clinical testing of
As chief of the section of pe-
ter for Medical Rehabilitation
therapies for AIDS patients, Bay-
diatric allergy and immunology
Research Advisory Board this
lor has established a new AIDS
at Baylor and of the allergy and
year. Frieden, Baylor assistant
Research Center.
immunology service at Texas
Z
professor, Physical Medicine &
"This is a tremendous oppor-
Children's Hospital, Shearer over-
B
Rehabilitation, is senior vice-
tunity for the researchers at Bay-
sees $3 million in AIDS diagnos-
B
president at The Institute for
lor to join forces and share their
tic and treatment programs this
Rehabilitation and Research
diverse knowledge about all as-
year for pediatric patients.
Z
(TIRR).
pects of the AIDS phenomenon,"
AIDS-related research at Bay-
The National Center for
said Dr. William T. Shearer, pro-
lor includes gene-therapy ap-
Medical Rehabilitation Re-
fessor, Pediatrics. "The center
proaches to stop the growth of
search, located at the National
also welcomes input from AIDS-
the human immunodeficiency
Institute of Child Health and
oriented groups within the com-
virus in infected patients; studies
Human Development, was
munity and other researchers
at the molecular level of how the
mandated by congressional leg-
virus behaves; potential treat-
A
J
within the Texas Medical Center.
islation in 1990. Its purpose is
This effort is solid proof of Bay-
(Continued on page 4)
Shearer with a patient.
Photo by Lindsey Kingston Lampp
to conduct and support studies
lor's commitment to solving the
in medical rehabilitation, to
mysteries of this catastrophic dis-
support research training pro-
ease."
grams, and to further research
Funding for Baylor's AIDS re-
on prosthetic devices and other
search has increased to $9.4 mil-
assistive technology.
lion for 1991 from $20,000 in
Jones Named to Brown Chair
The center's advisory board
1982. The AIDS Research Center
helps set research policy and
is administered by Shearer and
Chair is one of five endowed by The Brown Foundation at Baylor.
goals. It also reviews federal
codirector Dr. Janet S. Butel, pro-
research priorities, activities,
fessor and head, Molecular Virol-
Dr. Dan B. Jones has been
thalmology.
said. "His accomplishments as a
and findings related to medical
ogy.
named to The Margarett Root
"Dr. Jones is well-known for
researcher, clinician, and depart-
rehabilitation research.
A faculty advisory committee
Brown Chair of Ophthalmology
his expertise in the diagnosis and
ment chairman merit the ap-
oversees the center's efforts in
by Baylor President Dr. William
management of infectious diseas-
pointment to The Margarett
basic and clinical research and in
T. Butler.
es of the eye, particularly the
Root Brown Chair of Ophthal-
community-outreach programs,
Jones is the Sid W. Richardson
treatment of bacterial and fungal
mology."
such as the Thomas Street Clinic,
professor and chairman, Oph-
infections of the cornea," Butler
Two Foundations
Jones
Jones joined the Baylor facul-
Honor DeBakey
ty in 1972 as an associate pro-
fessor. He previously held posi-
Dr. Michael E. DeBakey
received the Lifetime Achieve-
ment Award from the Founda-
Baylor Prostate Center Created
tions at the Vanderbilt Universi-
ty School of Medicine and the
University of Miami School of
tion for Biomedical Research
Medicine.
at the organization's 10th an-
Four departments will sponsor studies of the prostate gland,
Along with his colleagues at
niversary gala. DeBakey is
Baylor's chancellor and chair-
including cancer, abnormal enlargement, and other diseases.
Baylor, Jones developed an ani-
mal model for studying endoge-
man of the Department of
The most common cancer in
tate gland. Research also will fo-
ter T. Scardino, professor and
nous candida endophthalmitis, a
Surgery.
American men will be studied at
cus on the understanding and
chairman, Urology, who will be
fungal infection of the inner
The award recognizes De-
treatment of diseases of the pros-
director of the center.
structures of the eye, and other
Bakey's contributions to medi-
a new multidisciplinary research
center at Baylor College of Medi-
tate gland, such as prostate can-
"This new center will help
models of corneal infection. He
cine and to the improvement
cine.
cer and benign prostatic hyper-
Baylor meet the explosive de-
currently is principal investigator
of human health through
years of medical research, ed-
The Baylor Prostate Center
trophy (BPH), or abnormal en-
mand by patients for access to
of a national collaborative clini-
will promote clinical and basic
largement of the prostate.
new diagnostic tests and treat-
(Continued on page 4)
ucation, and surgical practice.
These accomplishments
research on the anatomy and
"Prostate disease is a much
ments," Scardino said. "It also
also have brought DeBakey,
physiology of the normal pros-
understudied field," said Dr. Pe-
will help the College compete
for prostate-disease-related re-
along with corecipient Mary
search grants, which have grown
W. Lasker of the Albert and
tremendously."
Mary Lasker Foundation, the
One such award is a Special
Fourth Maxwell Finland
Program of Research Excellence
Award from the National
(SPORE) in Prostate Cancer,
Foundation for Infectious Dis-
which Baylor will apply for in
eases. Previous recipients in-
January. This National Cancer
clude Dr. C. Everett Koop,
Institute grant for more than
former Surgeon General of
$2 million a year requires institu-
the United States, and Dr. An-
tional support of comprehensive
thony S. Fauci, director of the
state-of-the-art research in the
National Institute of Allergy
biology, prevention, diagnosis,
and Infectious Diseases, Na-
DAN BONES
and treatment of prostate cancer
DEPT NTHALF
tional Institutes of Health.
through collaborations among
basic and clinical scientists.
The departments of Urology,
Pathology, Cell Biology, and
Medicine jointly sponsor the
Baylor Prostate Center.
Photo by Lindsey Kingston Lampp
Photo by Bharat Parikh
Scardino reviews a prostate ultrasound.
(Continued on page 2)
Jones
an abnormally enlarged pros-
By B.J.
tate. It sponsors educational
programs for presentation of
research results and helps de-
velop special resources, such as
tissue and blood samples for
research. Another function of
the center is the recruitment of
Algae Help Track Amino Acids in Body
residents and other investigators
for the field of prostate re-
Study could indicate best time to give infants essential proteins.
search.
Members of the Scientific
Algae may help a Baylor re-
scopic video camera to each
Advisory Committee to the Bay-
searcher at the Children's Nutri-
amino acid and following its
lor Prostate Center are Dr.
tion Research Center (CNRC) de-
travels through the body.
Michael W. Lieberman, profes-
termine if and when amino acids
Amino acids are classified as
sor and chairman, Pathology;
need to be added to an infant's
essential, nonessential, or condi-
Dr. Bert W. O'Malley, professor
diet.
tionally essential. The essential
and chairman, Cell Biology; and
Dr. Heiner Berthold, postdoc-
type comes from the diet. Nones-
Dr. Timothy C. Thompson, as-
toral fellow, Pediatrics, believes
sential amino acids are naturally
sistant professor, Urology and
this discovery may pinpoint
produced by the body. Condi-
Cell Biology.
which amino acids need to be
tionally essential amino acids are
supplied during periods of de-
produced by the body under cer-
The Prostate Gland
velopment and growth. He pre-
tain circumstances.
Located below the bladder
dicts that someday infant-formula
"It has not been easy to deter-
and above the rectum, the pros-
makers could fine-tune their
mine what these circumstances
tate gland is about the size of a
products to the precise needs of
are, especially in children,"
walnut. As part of the male
infants during the first few
Berthold said. "The traditional
genitals and urinary system, the
months of life.
method of determining essential-
prostate gland produces semen
Amino acids, the building
ity has been to eliminate an ami-
and requires the male hormone
blocks of proteins, are important
no acid from the diet. Obviously,
testosterone for normal func-
for vital processes, such as fight-
this method is not appropriate
Photo by Lindsey Kingston Lampp
tioning.
ing infection, controlling muscle
on infants."
Berthold prepares amino-acid samples for analysis.
Prostate cancer affects nearly
function, renewing cells, and
To see if a labeled food
122,000 men and kills more
producing hair.
source could track an amino
than 32,000 annually, making it
For his research, Berthold
acid, Berthold fed a hen a spe-
and conditions where nonessen-
nique is that it is safe to use in
the second leading cause of
uses a special form of algae
cial diet of the enriched algae
tial amino acids should be added
humans, including premature
cancer death among American
called Spirulina. To transform the
and tracked the carbon atoms.
to the diet.
infants, since the labeled atoms
men. Symptoms of prostate
Spirulina into a tracking device,
He discovered that the amino
Results also indicate that the
can be identified in waste prod-
cancer may include the inability
he substitutes carbon dioxide for
acid proline, found in the hen's
labeled algae can be used to de-
ucts such as urine and breath,"
to urinate, frequent urination,
the plant's normal carbon con-
tissues, contained the heavy at-
tect all the body's amino acids,
Berthold said.
painful urination or ejaculation,
tent.
oms, as did the whites of the
as well as fatty acids, sugars, and
But before scientists attempt
and blood or pus in the urine
This enriched carbon, called
hen's 23 eggs.
vitamins.
to use the method on infants,
or semen.
13C, is heavier than a body's nat-
"That meant the proline came
Berthold considers Spirulina
Berthold will continue his work
The cause of prostate cancer
urally occurring carbon and is
from the feed, and this implies
an ideal choice to label because
by examining adults who have
is unknown, but when detected
easy to identify in the laboratory.
that it is an essential amino acid
it is edible, it can be grown in a
received a dose of the labeled
in its early stages, the cancer
Once the normal carbon atom
instead of nonessential, as poul-
controlled environment, it is rich
algae.
often is curable with surgery
takes on the 13C content, it is
try experts have long believed,"
in protein, and it has a well-bal-
Berthold's findings were pub-
and/or medication.
considered a labeled food
he said.
anced amino-acid makeup simi-
lished in Proceedings of the Na-
By B.J. Almond
source.
The two-year study gives re-
lar to milk protein, casein, and
tional Academy of Sciences.
Berthold compares the track-
searchers a base of information
egg white.
By Lynn Foltin
ing process to attaching a micro-
about amino-acid production,
"The advantage of this tech-
2
Baylor Medicine
November 1991
Harvard Professor
Is Featured at
AV Materials on Spinal-Cord Injury Noted
First Lectureship
Data base at TIRR will provide free list of videos, films, and audiotapes on selected topics.
An internationally renowned
pathologist inaugurated the first
Videotapes about the special
in the United States have a spi-
Dennis T. Woznicki Lectureship
needs of persons with spinal-
nal-cord injury, SO there's a major
for Baylor's Department of Pa-
cord injury aren't as accessible as
need for instructional materials
thology.
copies of Home Alone and
of this type, according to Dr.
Dr. Ramzi S. Cotran, a pa-
Dances with Wolves, but re-
William H. Donovan, a Baylor
thology professor at Harvard
searchers at Baylor College of
Medical School and the head of
professor of clinical physical
Medicine and The Institute for
medicine & rehabilitation, who
the Department of Pathology at
Rehabilitation and Research
serves as project codirector for
Brigham and Women's Hospi-
(TIRR) have made it a lot easier
the data base.
tal, spoke on "Endothelial Acti-
for these persons to find out
The idea for the data base
vation: Its Role in Inflammation
what's available-and where.
and Vascular Injury."
was conceived by Dr. Karen A.
"Most people with spinal-cord
Hart, Baylor assistant professor
The lectureship, which will
injury and health professionals
of physical medicine & rehabili-
be held annually, pays tribute
don't even know these materials
to the late Dr. Dennis T.
tation, and TIRR vice-president
exist," said Linda Herson, Baylor
for education. Pilot funding was
Woznicki, a Baylor College of
senior project coordinator, Physi-
Medicine graduate and assistant
obtained from the American Spi-
cal Medicine & Rehabilitation.
Photo by Lindsey Kingston Lampp
professor of pathology who
nal Injury Association, along with
"The films and videos that have
Herson checks on a video listed in the data base.
died in 1989. The lectureship
support from TIRR and Baylor.
been made are available in so
During 1990-91, a grant from the
was made possible by Lavonne
many locations around the coun-
Education and Training Founda-
Woznicki, the honoree's wife;
try that it's been hard to know
spots, you can write or call the
er practical details.
tion of Paralyzed Veterans of
her family and friends; and
where to look."
data base at TIRR. Within 48
The data base compiled by
America supported further devel-
members of Baylor's Depart-
Now persons with spinal-cord
hours, by telephone or mail Her-
Herson over the past year con-
opment of the data base. During
ment of Pathology.
injury, their families, and health-
son will provide you with a free
sists of approximately 175 films,
1991-92, the data base will be
care providers just have to look
list of materials available on the
videos, and audiotapes. Among
expanded to include written ma-
one place-TIRR, a Baylor Affiliat-
topic in which you're interested.
the entries in the data base are
terials not available in libraries,
ed Teaching Hospital. The first
Each item on the list will in-
materials produced at TIRR-in-
such as pamphlets, booklets, and
national data base of audiovisual
clude a brief description of the
cluding resources translated into
home-care manuals prepared for
Prostate
educational materials geared to-
content, the address and phone
Spanish. Topics range from sexu-
patients by hospitals.
ward the subject of spinal-cord
number of the business or insti-
ality and aging issues to voca-
To retrieve information from
(Continued from page 1)
injury has been developed there.
tution from which the material
tional counseling and home
the data base, call Herson at 713-
The center provides core
If you want to know whether
can be purchased or rented, the
modifications for wheelchair ac-
797-5945, or write to the Division
there are videos or audiotapes
cost, the audience to whom the
support facilities for design and
cessibility. Also available are
of Education, The Institute for
analysis of research protocols,
about sit-skiing, the dangers of
material is targeted, the length of
tapes about safe driving and safe
Rehabilitation and Research,
including a large data base of
pressure sores caused by sitting
the program, the date the materi-
diving that are geared toward the
1333 Moursund, Houston, Tex.,
patients with prostate cancer or
in a wheelchair for too long, or
al was produced, the availability
prevention of spinal-cord injury.
77030.
November 1991 Baylor Medicine
3
Red-Cell Mystery Solved
Baylor investigators explain how astronauts' blood is affected in outer space.
Why do astronauts have fewer
C. Johnson, who was a Baylor
aged by senior research assistant
red blood cells when they return
clinical professor, Medicine, was
Theda B. Driscoll, compared all
from a space flight?
the first to observe this change
the blood samples.
Baylor researchers found the
years ago, Alfrey said.
answer by analyzing blood sam-
Alfrey was the principal inves-
A Lesson in Blood
ples taken from scientists aboard
tigator who planned the blood
About 45 percent of normal
the Columbia during its June
studies for NASA's Spacelab Life
human blood consists of millions
flight.
Sciences 1 mission on the Co-
of cells-mostly red cells, which
"Since the earliest space
lumbia this year.
carry oxygen; the other 55 per-
flights, astronauts have been
Four biological scientists were
cent is plasma-the liquid portion
modestly anemic when they re-
part of the astronaut crew on the
of blood in which cells are sus-
Photo by Bharat Parikh
Alfrey (left) with Driscoll.
turn from even very short peri-
Columbia flight. Before they left,
pended.
ods of weightlessness," said Dr.
the scientists received injections
It takes four to five days for
Clarence P. Alfrey, Baylor profes-
of red blood cells that had been
the body to make a red cell. Nor-
sor, Medicine. The late Dr. Philip
labeled with a radioactive sub-
mal red cells survive about 120
cells at the normal rate. The
marrow has the capacity to close
stance. By measuring the num-
days and then are constantly re-
body also continued to make
its gate and not let any new cars
ber of marked cells that re-
placed by newly produced cells.
new red cells in the bone mar-
out until the volume on the out-
Alfrey Honored
mained in blood drawn at inter-
More than two million red cells
row-as evidenced by the disap-
side lots is down," Alfrey said.
Dr. Clarence P. Alfrey and
vals during the spaceflight, re-
are destroyed each second, and
pearance of radiolabeled iron
The body develops a new op-
the other principal investiga-
searchers determined the rate at
the iron in them is reused in the
from the plasma. However, new
timal blood volume for weight-
tors for the Spacelab Life Sci-
which red blood cells were de-
bone marrow to make the same
red cells with the radiolabeled
lessness, he explained. "This fine
ences 1 mission have been
stroyed. Radiolabeled iron inject-
number of new cells. Only about
iron did not show up in the
control of blood volume is some-
chosen for the 1992 Jeffries
ed in space indicated the rate at
one percent of the body's red
blood.
thing we've not seen before."
Medical Research Award.
which the body was producing
cells is destroyed each day.
"The factory apparently con-
The National Aeronautics and
The American Institute of
new cells.
tinued to make new red cells,
Space Administration funded the
Aeronautics and Astronautics
During the flight, the scientists
What Happened in Space?
but it stopped releasing them
research. Dr. Mark M. Udden,
gives the award in recognition
took daily blood samples from
Studies of the blood samples
into the blood," Alfrey said.
Baylor assistant professor, Medi-
of outstanding contributions to
themselves. "Drawing blood
from the Columbia passengers
Sensors in the kidney main-
cine, was Alfrey's coinvestigator.
space biology and medicine
samples in space was a problem
revealed that the number of red
tain the body's blood volume by
For future space flights, Alfrey
that have resulted in signifi-
for the scientists," Alfrey said,
cells began dropping within the
controlling the production of red
will be studying ways to regulate
cant advancements in under-
"because, in the absence of grav-
first few days of flight. After
cells. Gravity causes all veins that
the blood volume. When astro-
standing basic physiologic
ity, the veins are not naturally
about a week, the decrease lev-
are below the level of the heart
nauts return to an atmosphere
mechanisms and the effects of
distended, or filled with blood."
eled off; by this time, the scien-
to be filled with blood. The lack
with gravity, their veins are sud-
weightlessness on human
Tourniquets had to be applied to
tists had 10 to 15 percent fewer
of gravity in space causes the
denly filled with the two units of
physiology.
create enough blood pressure
red cells-the equivalent of one to
blood to move to the central part
blood they lost during weight-
The award is named after
for an adequate blood withdraw-
two units of blood. The normal
of the body from the peripheral
lessness, causing dizziness and
fromaeine
impairing their mobility
the American physician who
made the earliest recorded sci-
After the scientists returned to
to 14 days after the return to
sensors in the kidney perceive
could be a problem if a quick
entific observation from the
earth, more daily blood samples
earth.
that there is too much blood and
evacuation is needed, Alfrey not-
air.
were taken.
During the spaceflight, the
stop the release of new red cells.
ed.
Alfrey's lab, which is man-
body continued to destroy red
"We've learned that the bone
By B.J. Almond
The Nose Knows
Metabolic Diseases that Cause Odors
Some diseases can be detected by odor.
Disease
Odor
Symptoms
Today's physicians may be ne-
and was so-named in the days
glecting vital tools in their diag-
when physicians used to both
Beta-Methylcrotonyglycinuria
Cat urine
High acid levels, feeding problems, vomiting,
nostic arsenal-their noses.
smell and taste the urine," Mc-
irritability.
Certain diseases that affect me-
Cabe said. Mellitus is derived
tabolism can cause the body to
Diabetes Mellitus
from the Latin word meli (hon-
Fruity, sweet
Elevated blood-sugar levels, sugar in urine,
emit smells similar to familiar
ey).
excessive thirst, itching frequently around
odors like maple syrup, cat urine,
PKU, which can result in se-
genitals; untreated, can cause a variety of
sweaty socks, and rotten fish (see
vere mental retardation, affects
medical problems, including blindness, and
chart).
one in 15,000 births. The musty
can be fatal.
"Some of the diseases can kill
or mousy odor that sufferers
infants within the first few weeks
Hypermethioninemia
Rancid butter or
emit does not begin until 3 to 6
Varied-may include liver abnormalities, muscle
or months of life," said Dr. Ed-
months of age, and since babies
rotten cabbage
disease, developmental delay.
ward McCabe, professor, Molecu-
are now routinely screened for
lar Genetics and Pediatrics. "An
Isovaleric Acidemia*
the disease and given treatment,
Sweaty feet, dirty
Lethargy, lack of appetite, high acid levels,
socks
alert doctor or parent can help
few develop symptoms.
seizures, coma.
offset major health problems,
Besides health problems,
since most of these metabolic dis-
some odor-causing diseases can
Maple Syrup Urine Disease
Maple syrup, burnt
Lethargy, lack of appetite, high acid levels,
eases are highly treatable."
be painfully embarrassing, such
caramel, curry
seizures; severity of symptoms varies
Such inherited diseases occur
as trimethylaminuria.
depending on type of MSUD (several forms).
in about one in 10,000 births.
"Children with this disorder
Many can now be detected
are sometimes treated like social
Methionine Malabsorption
Brewery, hops,
Diarrhea, convulsions, rapid breathing, white
through prenatal and postnatal
outcasts," McCabe said. "They
Syndrome (Oasthouse
yeast, dried celery
hair; can cause mental retardation; also known
screening and are often treated
are often accused of not bathing
Syndrome)
as Smith-Strang disease.
with special diets.
because their sweat and urine
smell like rotten fish."
Phenylketonuria (PKU)
Mouse urine,
Most common of odor-causing metabolic
Various Smells
Baylor's metabolic-disease
musty odor
diseases; not life-threatening but can cause
Maple Syrup Urine Disease
specialists receive inquiries on
mental retardation; routine screening at birth
causes the urine to smell like ma-
such unusual disorders from
prevents most cases.
ple syrup, burnt caramel, or curry.
around the world, McCabe said.
He advises parents and physi-
Trimethylaminuria
Although it has a funny name, the
Rotten fish, fishy
May be clinically normal except for odor or
odor
disease can be life-threatening in
cians to request genetic screen-
may have significant psychological problems
some forms if not detected early.
ing tests if there is prior knowl-
such as depression.
While most odor-causing dis-
edge of susceptibility to the dis-
eases. They also should inquire
Tyrosinemia
Musty odor
Low phosphate levels in blood; can cause liver
eases are rare, some are more
common, such as diabetes melli-
about what tests were done at
disease, kidney problems, rickets.
tus and phenylketonuria (PKU).
birth. And, he says, they should
"Diabetes mellitus produces a
use their noses.
*
A similar condition, glutaric acidemia, is nearly always fatal.
sweet, fruity smell in the urine
By Ron Gilmore
4
Baylor Medicine November 1991
Rare Skin Disorder Found
Researchers are making progress in their studies of a hereditary cancer
syndrome known as MEN 2A, or Sipple's syndrome.
Baylor scientists have identi-
responsible for insulin produc-
causes intense itching.
fied a variant of a rare hereditary
tion. Some tumors associated
Gagel and Dr. Donald T.
cancer syndrome. They hope to
with these hereditary diseases
Donovan, associate professor of
use information gained from
are malignant.
clinical otorhinolaryngology &
studies of this disorder to more
MEN 2A, or Sipple's syn-
communicative sciences, present-
accurately diagnose which chil-
drome, is a type of MEN associ-
ed their research at the Fourth
dren of an affected family will
ated with thyroid cancer and ad-
International Workshop on Multi-
inherit the mutated gene.
renal tumors, which can result in
ple Endocrine Neoplasia hosted
Photo by Bharat Parikh
The cancer syndromes known
heart irregularities and sudden
by Baylor and The Methodist
Donovan (left) and Gagel review the family tree of a group identi-
as "multiple endocrine neoplasia
death, said Dr. Robert F. Gagel,
Hospital.
fied with MEN 2A.
(MEN)" cause a variety of endo-
associate professor, Medicine
They are comparing the genes
crine tumors. These include tu-
and Cell Biology.
of the families that have MEN 2A
mors of the pituitary, parathy-
Children born to parents af-
to those of families with other
roid, thyroid, and adrenal glands
fected with MEN 2A have a 50-50
types of MEN to pinpoint the
able until the person at risk devel-
by genetic-screening techniques
and the portion of the pancreas
chance of inheriting the diseased
location of the mutated gene on
ops one of the manifestions of the
as a gene carrier for
MEN
2A.
gene, Gagel said. About 10,000
chromosome 10. Localizing the
syndrome. The abnormal gene
After her carrier status was con-
people worldwide have been
MEN 2A gene may be important
may be detected by measuring
firmed by blood test, the child
identified with this syndrome,
for understanding the molecular
the level of calcitonin in the
was cured of an early-stage thy-
Jones
which has been linked to chro-
mechanism of common cancers.
blood. A positive test result, how-
roid cancer by surgerry.
(Continued from page 1)
mosome 10.
"Cancer is likely to be a col-
ever, is not likely to occur before
Current dependence on blood
During their studies of MEN
lection of abnormalities at key
the age of five, Gagel said.
testing for diagnosis
of
MEN 2A
cal trial sponsored by the Nation-
2A, Gagel and his colleagues dis-
points or switches in the DNA,"
As a model for how clinicians
will end with the availability of
al Eye Institute on the treatment
Gagel said. "It's also likely there
can deal with this disease, Dono-
more closely linked
NA mark-
of herpes simplex eye disease.
are only a finite number of
van presented the case history of
ers of the abnormal ene, or its
Jones is chief of the ophthal-
switches. By identifying the ab-
a two-year-old who was identified
identification, Gagel
predicted.
mology service at The Methodist
"By identifying the abnor-
normal switch in a hereditary
By
James Russell
Hospital and at Ben Taub Gener-
cancer, we can find information
mal switch in a beredi-
al Hospital.
that will be relevant in treating
He is a member of the boards
tary cancer, we can find
other cancers."
of the American Academy of
information that will be
Gene-carrier status in affected
In Memoriam: Greer
Ophthalmology, Association of
families at risk for MEN 2A now
University Professors of Ophthal-
relevant in treating other
can be determined with a greater
Trustee emeritus S. Marcus
mology, Lions Eye Bank Founda-
cancers."
than 95 percent certainty with
tion, and William C. Conner
Greer died Oct. 29. He was 92.
molecular-genetic techniques,
"Mr. Greer was a devoted and
Foundation. He also is past
Gagel said. That certainty, how-
longtime trustee of Baylor Col-
tors of the American Board of
covered a skin disorder associat-
ommend removal of the thyroid
lege of Medicine," said board
Ophthalmology. He currently
ed with the cancer. They have
in a child for presumed thyroid
chairman James A. Elkins Jr. "His
serves as Secretary for Instruction
identified eight families world-
cancer without independent con-
contributions will always be ap-
for the American Academy of
wide with this abnormality,
firmation of the cancer gene.
preciated and remembered."
Ophthalmology.
which produces brown skin le-
Confirmation of gene-carrier
Greer joined the Baylor Board
of Trustees in 1969 after the
Prior to Jones' appointment,
sions over the upper back and
status for MEN 2A rarely is avail-
medical college separated from
The Margarett Root Brown Chair
Baylor University in Waco and
was occupied by Dr. David Pa-
became an independent institu-
ton, former chairman, Ophthal-
tion. The following year he ap-
mology.
plied his financial expertise as
vice-chairman of the College's
Brown Chair
Greer
Photo by Gitztings
first endowment campaign,
The Margarett Root Brown
which raised more than $30 mil-
Chair was established in 1970
lion. He also chaired the Adviso-
through a gift from The Brown
1985 he retired as chairman of
ry Council to the Neurosensory
Foundation Inc. of Houston. The
Center Campaign. He was
the Tanglewood Bank National
nonprofit, charitable foundation
Association.
named trustee emeritus in 1984.
was established in 1951 by Her-
Greer had been chairman
The Methodist Hospital, a
man and Margarett Root Brown
Baylor Affiliated Teaching Hospi-
The Moody Foundation in
and George R. and Alice Pratt
Galveston and had served as
tal, also benefited from Greer's
Brown for the betterment of hu-
talents. For at least 20 years he
member of various other corpo-
manity.
rate boards.
Photo by Lindsey Kingston Lampp
chaired the hospital's finance
Other chairs at Baylor en-
committee.
He graduated from The Unii-
dowed by The Brown Founda-
All in the Family
During his banking career,
versity of Texas in 1921 with
tion are The E.L. Wagner, MD,
Second-year medical student Erik Torgerson gives an anatomy
Greer served as president of First
BBA degree in finance. He re-
Volunteer Faculty Chair of Inter-
lesson to a tour group on Family Day. Sponsored by the Office of
City National Bank when it was
ceived UT's Distinguished Alurm-
nal Medicine, The Olga Keith
nus Award in 1963.
Alumni Affairs, the Family Day program included an orientation
Houston's largest bank. He also
Wiess Chair of Otorhinolaryngol-
session, lab demonstrations, and a luncheon for parents, grand-
had been chairman of the board
ogy, The Lodwick T. Bolin Chair
parents, spouses, and siblings of. first-year medical students. The
of directors of the San Felipe Na-
of Biochemistry, and The L.F.
program focused on establishing the foundation for a close-knit
tional Bank, and had served on
AIDS
McCollum Chair in Molecular
and enduring College family. About 270 family members and
the board of directors of the
Physiology and Biophysics.
(Continued from page 1)
first-year medical students attended.
Moody National Bank and of the
By Mark Seegers
Terrell State Bank of Terrell. In
ments for tuberculosis and other
AIDS-related complications that
include eye disease, AIDS-caused
Baylor Medicine
Non-Profit Org.
Office of Public Affairs, room 159B
U.S. POSTAGE
pneumonia, and lung and heart
One Baylor Plaza
PAID
problems.
Houston, Texas 77030
Houston, Texas
Permit 1492
Educational and preventive
ADDRESS CORRECTION REQUESTED
efforts include screening proce-
dures, AIDS prevention among
Vice-President
D. Gayle McNutt
Dir., Publications and
high-risk adolescents, and a pro-
Internal Communications
Sara Jo Thompson
gram to train volunteers and fos-
Editor
B.J. Almond
ter families to work with children
Editorial Assistants
Dana Morrison
James Russell
with AIDS.
Production Artist
Diana Wren
Houston is the fourth leadin
Production
Medical Illustration &
Audiovisual Education
metropolitan area in numbers
of
AIDS patients. Only New York
Baylor Medicine is published 11 times a year for the
Los Angeles, and San Francisco
College's friends and supporters, board, alumni,
faculty, students, bousestaff, and staff.
have higher incidences.
By Ron Gilmore