Ask the Scholar

Document scope · 1 page
doc
Scholar
Ask about this object, its catalog metadata, its source description, or the page inventory. For page-specific OCR and visual context, open one of the page chats.

Scholar Source Context

Document identity
localId
323152874
label
National Coalition on AIDS 3/29/90 [OA 6854] [2]
core
doc
dtoType
document
pageCount
1
Source metadata
Source extras
naId
323152874
levelOfDescription
fileUnit
recordType
description
ocrSource
nara-archive
Single page context
seq
1
pageIndex
0
type
document
mediaId
39555f5395ae0f41
ocrText
Originally Processed With FOIA(s): FOIA Number: Systematically Processed; 1998-0091-F 1998-0091-F FOIA MARKER This is not a textual record. This is used as an administrative marker by the George Bush Presidential Library Staff. Record Group/Collection: George H.W. Bush Presidential Records Collection/Office of Origin: Speechwriting, White House Office of Series: Speech File Backup Files Subseries: Chron File, 1989-1993 OA/ID Number: 13710 Folder ID Number: 13710-010 Folder Title: National Coalition on AIDS 3/29/90 [OA 6854] [2] Stack: Row: Section: Shelf: Position: FACSIMILE TRANSMISSION REQUEST FROM: (NAME, ORGANIZATION $ PHONE $ ) DDRESSEE: (NAME, ORGANIZATION, CITY, STATE & PHONE#) Bob SIMON JeRRy BeckeR White House 245-1856 456-2930 OTAL PAGES FAX MACHINE PHONE NUMBER( IF KNOWN) DATE CHARGE SYMBOL 12 456-6218 3/22 EMARKS F RETRANSMISSION IS NECESSARY CALL: HQS COMMCEN FTS 8-245-6277 CAC 202) WASH INSTRUCTIONS TO COMMCEN: (CHECK ONE) MAIL COPIES BACK TO ROOM /BUILDING CALL EXT WE WILL PICKUP/INCLUDE ROOM NUMBER RETAIN COPIES IN FILES COPIES NOT PICKED UP WITHIN 24-HOURS WILL BE RETURNED VIA MAIL. PRODUCT MIS. COMM. CEN. $2683.22 PM 2:30 SERVICE SEPT. OF HEALTH I 4123 3.22.1990 FROM March 22, 1990 FOR BOB SIMON, WHITE HOUSE SPEECHWRITING FROM: JERRY BECKER, HHS SPEECHWRITING. 245-7470 SUBJECT: Draft of Secretary Sullivan's speech to National Leadership Conference on AIDS. I am directed to send you this draft of recommended remarks for the Secretary's use at the March 29th conference. They have been reviewed internally and are to be submitted to the Secretary later today. Thanks very much. P. 2 3.22.1990 4:23 FROM RECOMMENDED REMARKS FOR SECRETARY LOUIS SULLIVAN, M.D. PLEASE NOTE REFERENCES TO INTERNATIONAL TRAVEL ON PAGE 7. SECRETARY'S WORKING COPY: March 22, 1990 EVENT: National Leadership Conference on AIDS AUDIENCE: 400 Business and Labor Leaders; some AIDS advocates TIME/DATE: 8 a.m. Thursday, March 29th PLACE: Crystal Gateway Marriott, Arlington FORMAT: 18 Minutes WRITER: JERRY BECKER, 245-7470 THIS DRAFT IS FOR THE SECRETARY'S REVIEW. THIS SPEECH WAS REVIEWED AND APPROVED BY OASH, HCFA, OGC, ASMB, AND SSA. ASPE REPORTED NONCONCURRENCE, SAYING THE SPEECH IS INACCURATE, DISJOINTED, INAPPROPRIATE AND DOES LITTLE TO ADDRESS THE DEPARTMENT'S ACTIVITIES ON HIV/AIDS. 2 'd 4:23 3.22.1998 1990 FROM 1 (The Secretary will be introduced by David Rogers, M.D., Chair, National Community AIDS Partnership.) Thank you very much, David. It is a great pleasure for me to be with you this morning. I consider this audience to be among the leaders in the fight against HIV infection and AIDS. I am delighted to join those from business, labor, and others who play a critical role in our nation's efforts to address the AIDS epidemic. Together, we will make progress. While AIDS is still a fatal disease, we can now call it a treatable disease, at least to the extent that we can delay the onset, or slow its progress. But "treatable" is not good enough for me. My goal is to make AIDS a curable disease. The irony is that AIDS is a preventable disease. I was asked to speak on AIDS and the federal agenda. since I time my speeches by the clock, not the calendar, there are limits to what I can cover. I will focus on what we are doing at Health and Human Services through our Health Care Financing Administration and the Public Health Service. I will offer some thoughts on international travel by those with HIV infection, and I will share with you the advice I give to health care professionals on their approach toward people with HIV and AIDS. First, I want to talk about HCFA, our Health Care Financing Administration. t 3.22.1990 4:24 FROM 2 HCFA plays a major role in financing health care services to people with AIDS. It does so under the Medicaid and Medicare programs. Most of the money HCFA spends on people with AIDS is spent through Medicaid, a medical assistance program jointly funded by the federal government and the states. Almost all people with AIDS who qualify for disability under the supplemental Security Income program are automatically eligible for Medicaid in most states. Forty percent of those with AIDS are served by Medicaid. In fact, about one-fourth of the total cost of direct medical care for all those with AIDS is met through the Medicaid program. We estimate that about one percent of the people with AIDS are covered under Medicare. It is reasonable to assume that because AIDS is now treatable, the number of people with AIDS who benefit from Medicare coverage of physician, hospital, and other medical care expenses, could increase over the coming years. During this fiscal year, federal expenditures for people with AIDS -- through Medicaid and Medicare -- will total $780 million, more than twice the amount provided only two years ago. State Medicaid expenditures are expected to total $630 million this year. S 'd 4:24 3.22.1990 FROM 3 For 1991, we seek over $1 billion to help those with AIDS through Medicaid and Medicare. In fiscal year 1992, spending on this aspect of our program is expected to go over $1.3 billion, and to nearly $1.7 billion in 1993. Let me emphasize that this federal spending is just through Medicaid and Medicare -- an essential part of what we do at HHS, but only part of what we do. We have continuing research programs underway to guide us in serving those who need help. Within HCFA, our Health Care Financing Administration, we will attempt to forecast the cost of AIDS based on information about the types of illnesses those with AIDS experience, their eligibility under Medicaid and Medicare, and the use they make of the services we offer. In addition, we will study the economic consequences of AIDS and HIV infection for Medicaid and Medicare programs under a variety of different policy assumptions. In treating AIDS, in attempting to move it from a fatal disease to a treatable disease and, yes, even to a curable disease, we are relying extensively on our Public Health Service. Your tax dollars have worked wonders there. Funding for the fight against HIV/AIDS through the Public Health Service was increased from $6 million in 1982 to almost $1.6 billion in this fiscal year. Next year, we expect to spend almost $1.7 billion. 9 4225 3.22.1990 FROM 4 What has the Public Health Service done for people with AIDS? Let me count some of the ways: The National Institutes of Health expanded AIDS clinical trials programs; funded 18 community based trial centers to gain a broader base of participation; and developed the rapid drug discovery program that is now capable of screening 40,000 new compounds annually. The Food and Drug Administration accelerated the review process of experimental therapies; expanded the use of investigational new drugs (INDs) to make experimental therapies more widely available. The Health Resources and Services Administration funded development of innovative health care delivery demonstration projects which includes models of coordinated care for pediatric patients and families. It also has demonstration programs to provide drug users coordinated primary health care and drug abuse treatments. The Centers for Disease Control expanded public education programs through newly developed targeted education programs for schools and college aged youth for those in and out of school. 2 'd 3.22.1990 4:25 FROM 5 It also expanded support for counseling, testing and partner notification to provide early diagnosis and education of people at risk. Our Alcohol, Drug Abuse and Mental Health Administration developed research programs on the most effective behavior change methods so as to work with people to reduce or eliminate their risky behavior. These are some of the things PHS does. I am proud of our department. The men and women at HHS work together. Those in the Health Care Financing Administration work with those in the Public Health Service to make certain that we fully coordinate our efforts to respond to the crisis of AIDS and HIV infection. In addition, HCFA helps state agencies coordinate their Medicaid efforts, and works with hospitals and other care providers to improve reimbursements under Medicaid and Medicare. As a well-integrated department, Health and Human Services is able to meet the needs of a diverse population with a variety of coordinated services -- all provided by one Cabinet-level department. These include disability benefits through Social Security and Supplemental security Income cash benefits; Medicaid and Medicare benefits; approval of drug therapies; innovative research in the basic sciences; and education for health promotion and disease prevention. 8 di 4:26 3.22.1990 FROM 6 There are many ways to save a life and to improve the quality of that life. It takes many different skills. We find them all at HHS, and we are proud of the progress that has been made in helping people with AIDS. We are the lead federal agency in the war against AIDS, and while there are far too many casualties, I am convinced that in time we will win this war. Let me return to one aspect of our program I just mentioned -- education. The simple fact is -- education works. If you, remember nothing else I say here, remember this: Education works. It prevents disease. Knowledge of how HIV and AIDS are spread will prevent infections in those not yet infected. And it will help prevent fear and prejudice caused by misinformation. We must share with others what we already know: HIV and AIDS cannot be spread through casual contact, such as in the workplace. I am a doctor, and I know what I am saying. Our experts have been watching for evidence that HIV/AIDS is spread through casual contact. There is no such evidence. So let me repeat, and let me emphasize: HIV and AIDS cannot be spread through casual contact. It is spread by unprotected sexual activity, including high- risk sexual activity, by sharing contaminated needles, and from an infected mother to her baby. 6 4:26 3.22.1998 1990 FROM 7 One issue that has received special attention recently is travel. I believe we should explore every solution, including a legislative solution, if necessary, to remove discriminatory barriers and make international travel by HIV-infected persons easier. We will explore all possible alternatives. We will be faithful to the health of the American people, fair to those infected, and guided by our understanding of the scientific facts, and not societal fears. There is one more point I would make today. Most of our health professionals are doing an outstanding job in treating people with HIV and AIDS. They are knowledgeable, caring, compassionate. And they are properly cautious. Let me focus on two professions, dentistry and medicine. Thirty percent of those with HIV infection find their first symptoms in the oral cavity. Their dental health problems are often painful, severe, complicated, and costly to treat. I find it fascinating and reassuring that of some 180,000 dentists in the nation, only one dentist has been found to be HIV-positive because of occupational transmission. The American Dental Association says this dentist often did not wear gloves, even though he had obvious breaks in the skin on his hands. Moreover, ADA says that he followed infection control procedures only intermittently. That is one dentist out of some 180,000. 01.0 3.22.1990 4:27 FROM 8 I will note that a second dentist was found to be HIV- positive during a screening; however, not enough information is available to confirm that this case is due to occupational transmission. I must also add that there are 89 dentists reported with AIDS, but they have risk factors that are not related to their profession. Now let me turn to physicians. There is evidence that in choosing residencies, some medical students may be moving away from specialties and locations in which the care of AIDS patients is concentrated. A survey of recent medical school graduates reported that one-in-four said they did not want to treat AIDS patients because of the risks. We need more qualified and compassionate people to treat people with AIDS, not fewer. AIDS is different from other diseases to which physicians, dentists, nurses and other health professionals are at risk. While we have always gone where communicable disease is rampant, those diseases over the past half century have almost always been seen as treatable. AIDS is just now becoming treatable. P.11 4:22 3.22.1998 1990 FROM a I am proud of all of our health professionals, and yet I know that there are some whose compassion antennae require adjustment when treating people with HIV and AIDS. The health care industry is being tested. Medicine, dentistry, nursing and all of the other health care professions are not private professions. They are a franchise granted by society. Health professionals must remember that they were given the opportunity to become successful and respected care givers because society has underwritten the real costs of their education. There is a compact between medical professionals and all of those who provide grants and gifts from the public and private sectors. That compact requires health care professionals to be of service to society. so if there are some health professionals who must heal themselves of the horror and hatred in their hearts before they can free a nation of its fear of AIDS, then let the healing begin. There are times when a legislative remedy is one solution to discrimination. That is why I join the President in his call for the House to match the Senate in approving legislation that will help prevent overt discrimination against those with HIV infection or AIDS, and other types of disability. P.12 4:28 3.22.1998 FROM 10 Yet law alone cannot solve all of our problems. No one sector of society can stem the tide of infection, provide all of the care and treatment, all of the research and all of the education required to put HIV/AIDS in perspective and prevent their spread. This is a job that must be done at many different levels, by many different people. Yes, the federal government has its role, but so do state and local governments, and so does the private sector, voluntary societies, and those who advocate the rights of people with AIDS. Martin Luther King, Jr. once said that, "the ultimate measure of a man [or woman] is not where he [or she] stands in moments of comfort and convenience, but where he [or she] stands in times of challenge and controversy." I know where you stand. You are there with the baby with HIV infection. You are with adult men and women who suffer from AIDS and, yes, still die from it. You stand with those who seek treatment and are well enough to return to work and resume their productive place in society. You stand with the providers and researchers. In the midst of the battle, you stand at the front of the line, and I salute you. #### 3113 4128 3.22.1998 FROM THE WHITE HOUSE WASHINGTON March 20, 1990 TO: CHRISS WINSTON Attached are some points which may prove helpful in drafting the AIDS speech. This particular group is high-powered, and has been largely organized as a means of involving the business community in the fight against AIDS. I think Burt Lee can vouch for them. Thanks. fin Jim Cicconi NATIONAL LEADERSHIP COALITION 1990 MAR 20 AM 10: ON AIDS 19 March, 1990 BOARD OF DIRECTORS Officers John R. Taylor Chairman & CEO (Ret.) The Principal Financial Group Via Messenger Chair J. Richard Munro Chairman & CEO Time Warner Inc Jim Cicconi Vice Chair The White House David N. Sundwall, M.D. Vice President Washington, D.C. AmHS Institute Vice Chair Karen Ignagni Dear Jim: Assoc. Dir., Occupational Safety and Environmental Affairs, AFL-CIO Secretary Thanks for your interest in the National Business Leader- Michael Pollard Partner ship Conference which President Bush will address March 29th. Michaels & Wishner, P.C. The program for the conference, and a one-page description Treasurer B.J. Stiles of our goals and purposes are enclosed. President Members You agreed to take a look at suggested highlights for the Gwynn C. Akin, Ph.D. speech. I've done such a draft, which is attached. Syntex Corporation Lewellys F. Barker, M.D. American Red Cross One component not in this draft is a roster of companies, Nora Kizer Bell, Ph.D. CEOs, and business group which warrant specific acknowledg- University of South Carolina Erline Belton ment for their outstanding responses to AIDS. I did not Digital Equipment Corporation include such citations, as someone advised that it was against Edward N. Brandt, Jr., M.D., Ph.D. College of Medicine, Oklahoma University White House policy to include such specific citations without Health Sciences Center prior approval from such sources. I assure that we could Sharon Canner National Association of Manufacturers obtain such approval, or direct the appropriate office at Glenn E. Haughie, M.D. the White House to the source if that is the preferred mechan- International Business Machines Corp. ism. Generic thank-you's aren't quite sufficient for AIDS, William R. Hendee, Ph.D. American Medical Association and I know that those in the vanguard of providing business Stephen E. Herbits and civic leadership will find their jobs far easier if Joseph E. Seagram & Sons, Inc. Presidential acknowlegments are possible. Stanley G. Karson Center for Corporate Public Involvement Larry Kessler Some of those in the vanguard are cited in the enclosed AIDS Action Committee of Mass. publication, Business and Labor Speak Out on AIDS. But Bryan Lawton, Ph.D. Wells Fargo Bank there are others. Sam S. McKeel The Sun-Times Company Stephen T. Moskey Thank you for any counsel you can provide. Aetna Life & Casualty T.M. (Terry) Mulready Cordially Pacific Bell Emilio R. Nicolas, Jr. KMEX-TV, Los Angeles Beny J. Primm, Jr., M.D. Addiction Research Treatment Corporation Mervyn F. Silverman, M.D. B.J. Stiles American Foundation for AIDS Research President The Rt. Rev. William E. Swing Episcopal Diocese of California Larry H. Williford BJS/st Allstate Insurance Company Enc. 1150 17th Street N.W. Suite 202 Washington, D.C. 20036 202/429-0930 FAX: 202/872-1977 NATIONAL 19 March 1990 LEADERSHIP COALITION ON AIDS National Business Leadership Conference on AIDS March 29, 1990 I. The AIDS epidemic is far from over; we face great challenges ahead. We must work together. This is a painful, difficult disease and we're losing far too many Americans. You heard the specifics earlier this morning from Secretary Sullivan, Dr. Fauci, and Dr. Curran. Just as important are the panels (of the Quilt) which hang around us today. Like each of you, Barbara and I have lost too many friends to AIDS, and these celebrations of their lives remind us that each number we hear is about a human being. Although AIDS is a fatal disease, we will have far more people living and working longer with AIDS. That means the opportunity to live and work together, and to help one another. II. Private sector responses to AIDS have been outstanding, but the job isn't finished. We must do more. Business and labor have stepped forward, and in some communities you have been among the pioneers. Yet, it seems that only about 20 percent of the largest companies are doing much about AIDS, and we must get others to follow your lead. Most of the business response has been from the nation's largest companies, but as the epidemic spreads and worsens, small and medium sized businesses will also be affected. Corporate giving to AIDS has grown, and I am pleased to know that private foundations and corporations have given over $100 million to support thousands of AIDS projects. But now is not the time to slack off or abandon these important commitments. I believe that the next $100 million- or more--will bring us closer to winning this battle. Press and media have been important allies in getting the AIDS message to everyone. But some are tired of the story, or believe there isn't a new angle or hook. Please don't stop now. The message is too urgent. The lives of countless Americans depends upon understanding how the HIV virus is and is not transmitted, and the mass media plays a critical role in helping change behaviors and attitudes. The churches, synagogues, and spiritual leaders of America are getting involved, and I hope that more will come forward. We need you to help ensure that people with AIDS aren't rejected by their families and neighbors: to help provide care--to literally offer food, clothing and shelter for those suffering from AIDS. I call upon America's religious leaders--lay and clergy--to increase the love and compassion SO badly needed and to dispel the anger and rejection directed toward those with AIDS. We must all resist the instinct to blame the sufferer, and instead find solutions for the suffering. III. Federal, state and municipal resources have been marshaled to provide critical support, but the job isn't finished. We in government must do more, too. We are committed to federal support for all the core components of the epidemic: research, education, care and services, and treatment. We must ensure that no person with AIDS or affected in any way by AIDS is subjected to discrimination. That is one of the foremost messages from Admiral Watkins and his colleagues on the Presidential AIDS Commission, and this Administration is in complete agreement. I want to restate my full support for passage of the Americans with Disabilities Act still pending before Congress, and ask you to join me in seeking swift passage of this important bill. Although we remain opposed to categorical approaches to solving problems, I believe that the special impact of AIDS on parts of our society are SO burdensome and costly that I am today announcing support, in principle, for legislation to help locales especially burdened by AIDS, and for individuals with AIDS who fall outside the health care system in this country. We have the mechanisms to respond promptly to disasters like hurricanes, earthquakes, and tornadoes. We must consider how to provide similar assistance for those hardest hit by the AIDS epidemic. I return to the importance of education, and commend you in the business community who are providing excellent HIV information for your employees, their families, and the communities in which they live. Today I am asking each Member of the Cabinet to identify how we as government employers can increase our effectiveness in helping to educate all federal government 2 employees about AIDS. The guidelines already developed by the Office of Personnel Management are excellent; we now need to make them known throughout the government workforce. In conclusion, I want to strongly endorse the work of those here today, and those you represent, in marshaling support from the private sector to help us resolve the pain, fear, and stigmatization surrounding AIDS. This nation has never shirked a challenge of this magnitude, and we will not turn our back on this one. We have the mechanisms at our disposal. This Administration does care and is resolved to work together with you and others in containing this threat to our personal and social welfare. We will work diligently with the Congress and leaders of both parties to pass the Americans with Disabilities Act, and to develop any other legislation required to ensure that persons with AIDS do not suffer discrimination. We welcome the work of the National AIDS Commission and look forward to close communication with one another as they continue to examine what is needed to resolve this painful, costly, and complex epidemic. We urge you who are here today to return to your places of work, and take this message to your co-workers and bosses: The AIDS epidemic is not over, and we cannot sit back and leave this challenge to others. We must do our share. 3 NATIONAL LEADERSHIP COALITION ON AIDS BOARD OF DIRECTORS Officers NATIONAL BUSINESS LEADERSHIP CONFERENCE John R. Taylor Chairman & CEO (Ret ON AIDS The Principal Financial Group Chair March 29, 1990 J. Richard Munro Chairman & CEO Time Warner Inc. Purpose of this meeting: Vice Chair David N. Sundwall, M.D. 1) To convene 400 top business executives, labor leaders, Vice President AmHS Institute and others in a one-day session to address the impact Vice Chair of AIDS in the 1990s, with special focus on the Karen Ignagni Assoc. Dir., Occupational Safety and consequences for the business community. Environmental Affairs. AFL-CIO Secretary Michael Pollard 2) To provide a platform for the President to address the Partner Michaels & Wishner, P.C. nation on this critical subject. Treasurer B.J. Stiles 3) To marshal further support from the private sector to President respond to the growing needs stemming from the AIDS Members crisis. Gwynn C. Akin, Ph.D. Syntex Corporation Lewellys F. Barker, M.D. Goals for this meeting: American Red Cross Nora Kizer Bell, Ph.D. University of South Carolina 1. To underscore the considerable impact of AIDS on all Erline Belton Americans, and to highlight the necessity for an Digital Equipment Corporation Edward N. Brandt, Jr., M.D., Ph.D. ongoing response to the epidemic. College of Medicine, Oklahoma University Health Sciences Center Bottom line: AIDS is not over; even more will be Sharon Canner National Association of Manufacturers required from all of us in the decade ahead. Glenn E. Haughie, M.D. International Business Machines Corp. 2. To acknowledge the role which the private sector has William R. Hendee, Ph.D. American Medical Association played in reducing infections; providing support; and Stephen E. Herbits creating a compassionate and favorable response to all Joseph E. Seagram & Sons, Inc. those affected by AIDS. Stanley G. Karson Center for Corporate Public Involvement Larry Kessler Bottom line: Many in the private sector--especially AIDS Action Committee of Mass corporate America--are likely to back away from Bryan Lawton, Ph.D. Wells Fargo Bank continuing attention to AIDS unless there is strong Sam S. McKeel Presidential encouragement and new incentives. The Sun-Times Company Stephen T. Moskey Aetna Life & Casualty 3. To send participants in this meeting back to their T.M. (Terry) Mulready offices with a clear Presidential mandate, and some new Pacific Bell insights which will provide their bosses and colleagues Emilio R. Nicolas, Jr. KMEX-TV. Los Angeles with a renewed understanding of the nature and scope of Beny J. Primm, Jr., M.D. the epidemic. Addiction Research Treatment Corporation Mervyn F. Silverman, M.D. Bottom line: Don't back away; get more of your American Foundation for AIDS Research The Rt. Rev. William E. Swing associates and neighbors involved. Don't go it alone; Episcopal Diocese of California work with others, especially public health and Larry H. Williford Allstate Insurance Company community service organizations, religious leaders, and other business and labor groups. 1150 17th Street N.W. Suite 202 Washington, D.C. 20036 202/429-0930 FAX: 202/872-1977 The National Business Leadership Conference on AIDS March 29, 1990 Crystal Gateway Marriott, Arlington, VA Tentative Agenda 7:30 a.m. - 8:30 a.m. Registration Continental Breakfast 8:30 a.m. Welcome and Introduction Speakers: Lawrence H. Williford Senior Vice President Allstate Insurance Company John R. Taylor Chair, Board of Directors National Leadership Coalition on AIDS David E. Rogers, M.D. Chair National Community AIDS Partnership AIDS and the Federal Agenda Speaker: The Honorable Louis W. Sullivan Secretary Department of Health and Human Services A Critical Look at AIDS in the '90s Research and Treatment Issues Speaker: Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases The Numbers and What They Mean Speaker: James W. Curran, M.D., M.P.H. Director, Division HIV/AIDS Center for Infectious Diseases Centers for Disease Control AIDS From A CEO's Perspective Speaker: Robert D. Haas Chairman and Chief Executive Officer Levi Strauss & Co. SPECIAL KEYNOTE ADDRESS (CONFIRMED) Speaker: PRESIDENT GEORGE BUSH Tentative Agenda, Page Two Luncheon Luncheon Speaker J. Richard Munro Co-Chairman and Co-Chief Executive Officer Time Warner, Inc. Belinda A. Mason President, National Association of People With AIDS, and Member, National Commission on AIDS Health Care Costs and the HIV Epidemic Speaker: Carl J. Schramm President Health Insurance Association of America Labor Responses to AIDS Speaker: John J. Sweeney International President Service Employees International Union Living and Working with AIDS Interviewer: Renée Poussaint News Anchor WJLA-TV Panelists: Erline Belton Manager, Corporate Employee Relations Digital Equipment Corporation Cleve Jones Founder The NAMES Project Phil K. Morrow Founder and President, IMDT, Inc. Board of Directors, AIDS Services of Dallas 3:30 p.m. Close EDITED. BY Elizabeth Fee AND Daniel M. Fox AIDS THE BURDENS OF HISTORY Guenter B. Risse Epidemics and History 55 54 The certificate was routinely requested from all children under the age susceptible children who lacked natural immunity.106 "Perhaps twenty- of sixteen before embarkation for travel at all ferry and rail terminals as five years from now our present prophylactic efforts may appear to have well as steamboat piers. Those who managed to leave without such been too troublesome, over strenuous, or even ill advised," conceded cards were not allowed to disembark at their destination.99 one editorial in a medical journal. 107 With the epidemic now abating, it Although thousands of certificates were issued in the following weeks, was safe to criticize such measures. In nearby Oyster Bay irate fathers many communities around New York City refused to accept them. interrupted a town council meeting on August 28 demanding the return Some demanded similar documents from the accompanying adults, and of their children who had been removed to isolation hospitals. The local other communities, such as those in Connecticut, quickly escorted ar- quarantine was branded as another instance of "propaganda to terrify riving families out of town and abandoned them in open fields. One the people." 108 child from Brooklyn, who possessed a health certificate, came down One cannot avoid noticing a sobering skepticism which overtook with polio in Rochester, forcing Emerson to reiterate that the examina- public health officers, medical practitioners, and scientists as the polio tion given prior to issuance of a permit card could not detect disease epidemic of 1916 came to an end. The New York City Health Depart- during the early stages of incubation.¹⁰ ment had tried in part to control the outbreak by teaching the public Given the presence of large numbers of healthy carriers, Emerson ac- everything known about the disease with the help of professional groups, tually questioned the ban on travel out of New York City. In his view, volunteer organizations, the press, and leaflets. After all, responsibility such quarantine measures were futile and had no effect on the spread of for infectious diseases had significantly shifted in the twentieth century the epidemic. "I know that nothing has developed so many automobile from the environment to individuals, their way of life, and behavior. But detours, such ingenuity in the violation of the laws, and such whole- public education alone was certainly not enough; it only heightened the hearted disrespect for reasonable sanitary law and its enforcement." 101 fears of many, failed to reach-others because of ethnic and social bar- Strangely enough, Emerson's opinion about quarantines outside New riers, and, moreover, failed to stem the epidemic. York was totally at odds with his strong belief in their utility within Emerson was persuaded to adhere to sanitary principles and isola- tion methods employed since the Renaissance. As he wrote: "Health of the city. Emerson's reference to travel detours was pertinent. Anxious parents the individual is a public asset in which the civil government has an in- planning summer outings or more extended vacations flooded the Auto- terest and for the protection of which broad police powers may be exer- mobile Club of America with requests for routing around the more than cised." Such functions were specifically authorized by law, then exe- five hundred quarantines imposed by towns and villages bordering New cuted and enforced for the public good at the expense of individual York City. In many instances guards with red flags were posted at the rights. Environmental sanitation, quarantines, and isolation of the sick entrance of such towns, stopping every automobile and carefully search- were among the key objectives of such a campaign. ing for concealed children. Those carrying anybody under the age of None of the approaches was entirely successful. "As to the lessons we sixteen had to report to police stations or health offices.¹⁰² "I hardly have learned during the epidemic," declared one physician, "we have need to recall the countless instances of inconvenience, hardship, yes, learned very little that is new about the disease, but much that is old real brutal inhumanity which resulted from the application of the general about ourselves.' 110 Scientists were still debating the nature of the agent quarantine," admitted Emerson.¹⁰³ No wonder so many people "devel- 104 causing polio and its method of transmission. Physicians, while express- oped a most perverse ingenuity in discovering automobile detours." ing appreciation for the great clinical opportunities furnished by the epi- During the month of August, reported cases of polio began to ebb, demic, argued about the usefulness of spinal fluid examinations and and doubts were increasingly voiced concerning the success of Emer- convalescents' serum treatments.¹¹ Five hundred children with varying son's quarantine measures. The vector theory of the stable fly was dis- forms of paralysis presented formidable challenges to those entrusted credited;¹⁰ dissemination of polio was now thought to occur mostly via with their rehabilitation. unrecognized carriers through person-to-person contacts. It was also And then there was public health. Isolation and quarantine had ap- thought that the decline in polio cases resulted from the depletion of peared to help stem the onslaught of polio. But, did they really, or was 52 Guenter B. Risse Epidemics and History 53 disclose," wrote one editorialist.88 Indeed, the poor lacked the airy, trying to educate families at risk proved only partially successful. The clean, and cheerful rooms which Emerson recommended for the domes- pitch was directed to the children of immigrants themselves, who appar- tic treatment of polio cases. They seemed unable or even resistant to fol- ently grasped the importance of the measures before their parents; be- lowing the rules of hygiene which presumably contributed to a disease- cause of cultural and language barriers, these parents were less amena- free environment. "Defilers of the streets are to blame," commented one ble to the sanitary gospel. "Results obtained among adults were largely writer.89 Even New York's mayor stressed cleanliness. "There is no oc- due to fear of authority and the force of the department and not to vol- casion for alarm or panic," read Mitchell's statement published July 9 untary action on their part," commented one newspaper editorial.94 "Careful observance of the simple directions given by the Health De- There was, of course, resistance to the actions of the Health Depart- partment as to personal and household cleanliness will go far to prevent ment. As the seemingly conflicting messages of environmental hygiene further spread of or exposure to infection." and personal contagion took hold, fear began to grip the wary. "Many Not surprisingly, poor Italian families bearing the early brunt of the a family of children was housed for weeks, often in tight-shut rooms, epidemic were suspected of having introduced polio from their home- the children's pale faces pressed against the window panes, mute evi- land, although inquiries by Emerson to the quarantine station at Ellis dence of their unreasonable imprisonment," recalled Emerson.⁹⁵ Others Island failed to confirm such an impression. Both the immigration au- slammed the door in the faces of visiting nurses, who were suspected of thorities and American consular staff in Italy declared that no polio carrying polio from one family to another. One nurse stationed at a pe- cases had been reported in that country. In spite of such reassurances, diatric clinic in Brooklyn, who had repeatedly reported cases of the dis- suspicion lingered and quickly included Lower East Side Jews and Poles, ease as well as violations of the sanitary code in "Pigtown," received a who also furnished a disproportionate number of polio cases. Certain life-threatening "black hand" letter and from then on had to be escorted neighborhoods appeared to be especially dangerous. One of them was by a policeman between her home and place of work. "Pigtown," an Italian section of Brooklyn around Albany Avenue and The Red Cross, in turn, provided its nurses for home visits because Maple Street.91 they apparently generated less fear among mothers who worried that As the toll from the epidemic mounted in July, the New York Health their children would be summarily confiscated and removed to hospi- Department increased its "war" against the crippling scourge. Among tals. The latter were rumored to be hotbeds of polio infection easily the newly recruited "forces" were 21,000 citizens organized by the city's transmitted to arriving children and health personnel. Even many pri- police commissioner under the banner of "Home Defense League." Its vate schools and colleges refused to admit students on trivial grounds." members spread out to every precinct, where they worked thirteen-hour By mid-July publicity surrounding the polio epidemic in New York shifts accompanying policemen on patrol and searching for violations of City prompted a major effort by neighboring communities and indeed the sanitary code. Grocery stores, fruit markets, and street vendors the rest of the nation to confine the city's children within the metro- came under strict surveillance. One hundred and fifty gangs with water politan area, thus avoiding a possible spread of the disease to other trucks were placed into service. All theaters and movie houses were cities and villages. Towns on Long Island, a favorite summer destination closed to children under the age of sixteen.⁹² for countless New York families, placed billboards at their city lim- Public acceptance of and cooperation with such a health campaign its urging city dwellers with children to return home. Hotel-owners ad- were critical, and Emerson was quite aware of the difficulties awaiting mitting them overnight were heavily fined. At numerous railroad sta- him if he failed to persuade the community through educational means tions families traveling with children were turned back or placed under about the importance of sanitary and quarantine measures. "Anything observation.⁹⁸ which causes antagonism of the public to the policy of reporting and With assistance from the U.S. Public Health Service, the New York removal to isolation hospitals, develops deception, hiding of cases, and Health Department agreed to issue one-day health certificates or trav- such methods of obstruction as to frustrate to a great degree any ap- eler's identification cards, certifying that the child was free of symptoms proach to successful separation of the sick from the well."93 But how and did not come from an infected household. The same document could the public be convinced? Repeated visits by public health nurses could also be obtained from a private physician after an examination. Guenter B. Risse 50 Epidemics and History 51 Mothers were advised to bring all febrile children, especially those with Because the spread of the disease was unpredictable-ignoring class dis- "weak legs" or to send for a doctor.⁷⁷ All physicians in affected areas tinctions and geographical boundaries-the idea of an environmental were urged to cooperate. Moreover, the authorities offered diagnostic factor responsible for transmission of the disease was quite appealing. lumbar punctures and spinal fluid examinations free of charge. Moreover, experiments carried out in 1912 by Milton Rosenau, a pro- As the house-to-house searches were stepped up with the help of ad- fessor of preventive medicine at Harvard, suggested that flies, especially ditional inspectors and nurses, quarantine procedures went into effect the biting stable fly, could transmit polio. Although the importance of to isolate the suspected victims of polio.⁷⁸ Many children were promptly this possible vector was still under investigation, the Health Department and forcibly separated from their parents and removed to specially out- could not ignore it.83 All scientific studies concerning infantile paralysis fitted pavilions at nearby hospitals for proper diagnosis and treatment. were problematic at this time. Although a virus believed responsible for Initially, most patients arrived at Kingston Avenue and Queensboro hos- the disease had already been isolated in 1909, virology was still in its pitals.⁷⁹ Only two visits to the sick by members of the family were infancy; given the contemporary climate of fear, no one could take any allowed over the next eight weeks. Confirmed cases of the disease were chances.84 made public, and their names as well as addresses were published daily The New York Health Department therefore embarked on a vigorous in the newspapers. Parents were urged to read the lists and keep their cleaning campaign. Four million gallons of water were dumped daily children far away from the infected places. Houses yielding victims of on the city's streets, paradoxically before the garbage was hauled away. the disease were immediately placarded. Like a scarlet letter, the clearly Refuse and ash piles accumulating in halls of tenement houses and on visible sign was placed outside on the street front and in tenement build- sidewalks had to be removed. All stray cats and dogs were collected; ings on the street door, entrance hall, and apartment door. Inspectors according to the Society for the Prevention of Cruelty to Animals, three checked on the yellow signs daily, trying to discourage their removal, hundred to four hundred fifty cats and dogs were put to death daily in which was subject to a heavy fine.80 early July. Flyswatters and screens to fend off the gregarious stable fly Well-off parents, of course, could keep their sick children if they and its less aggressive domestic cousin were widely dispensed. Parents could provide them with a separate room and adequate nursing as well were urged to keep their homes spotless, and to go over all woodwork as medical care. Such isolation lasted eight weeks and required compre- daily with a damp cloth, sprinkling floors with damp tea leaves or hensive cleaning of the premises, provision of separate bedding and shredded newspaper before sweeping; to take daily baths; and of course, utensils, and careful disposal of bodily discharges. If a child died at to keep covers over each garbage pail.85 home, coffins were immediately sealed and burial occurred without a Homeowners caught depositing refuse on the streets were fined. church ceremony. Houses were thoroughly fumigated and new wall- Brooklyn, an early locus of the epidemic, became the black sheep in the paper installed. All surviving siblings under the age of sixteen were eyes of Commissioner Emerson. He accused its citizens of lacking enough quarantined in the house for the next two weeks.8¹ civil pride to keep their streets clean, suggesting that perhaps they were To ensure public support for such draconian isolation measures, responsible for the abundance of cases there.86 An army of thousands of Haven Emerson and his Health Department prepared half a million volunteers began patrolling the neighborhoods on foot and on motor- yellow leaflets for distribution. New Yorkers were told that polio was "a cycles, checking for violations of the Sanitary Code. By July 11 the au- catching disease," its method of spread "not yet definitely known." Its thorities had already charged 148 individuals with violations; even- germ was present in discharges from the nose, throat, and bowels of ill tually 2,266 such summonses were listed.87 and even healthy persons, and therefore it was essential for children to As most public health measures increasingly focused on environmen- stay away from crowds in parks, swimming pools, movie houses, and tal filth and garbage, polio began to be viewed as another plague of pov- stores. Fresh air, wholesome food, shower baths, and general cleanliness erty primarily affecting the same marginal slumdwellers who had been were recommended as the best prophylaxis.82 blamed for previous epidemics. "If we could get rid of ignorance and the The role of filth in poliomyelitis and its implications for public and filth and superstition that go with it, there would be little need to hunt personal hygiene was ambiguous but attractive to public health officials. down the mysterious germs that no filter can stop and no microscope 48 Guenter B. Risse Epidemics and History 49 thing seems to be resuming its wonted appearance." The sky, clear be- public health authorities everywhere carefully monitored its appear- cause of idle factories and unused domestic fireplaces, gave way again to ance. This was especially true during the summer months, when polio "the dense cloud of smoke which always lays over the city." was known to strike. Authorities in New York were especially on alert As in the previous case of plague, the cholera epidemic of 1832 con- because the city had already suffered two serious epidemics of the dis- stitutes another paradigm for social responses to disease. Here again, ease in 1907 and 1910. The new administration of Mayor John P. the poor-often immigrants-were the primary victims both of the dis- Mitchell was proud of its Health Department. This unit was composed ease and of the blame. In this view, moral failings thought to be respon- of competent professionals and led by Haven Emerson, a former medi- sible for poverty and dissipation provided a fertile substratum for chol- cal practitioner who had treated the last cases of cholera. Successful era to break out among those marginal sectors of society "different" campaigns against unsanitary boarding rooms, subway and streetcar from the hard-working, God-fearing majority. Public health measures crowding, as well as trade in patent medicines had bolstered the depart- sought to clean up the environment, thus reassuring the anxious public, ment's morale. In the eyes of its officials, a declining infant mortality but the activities were selective: Slums such as the Five Points area con- rate testified to the city's sanitary standing. Its combined population tinued to wallow in garbage and to be without fire protection. Epidemic from all five boroughs was estimated at 5,570,000.73 disease served once more as a focus for the expression of religious, po- All but forgotten in the midst of an election year, the war in Europe, litical, and cultural biases within society. and a Mexican-American crisis prompted by Pancho Villa's raid, the first cases of polio in New York were reported on June 6. All of the sick children came from a densely populated section of Brooklyn near the POLIO waterfront, primarily populated by Italians. Visiting nurses making a The third and final case study presented in this chapter deals with the house-to-house search soon discovered another twenty-two victims of serious epidemic of poliomyelitis, or infantile paralysis, which erupted the disease, some ill for several weeks but not severely enough to de- among inhabitants of New York City in the year 1916. The disease had mand medical attention.74 been rare before 1907, although minor episodes occurred in Austria There was no denying it. Polio had returned to New York. In the fol- (1898) and Scandinavia (Norway and Sweden, 1904). In Rutland, Ver- lowing days 327 new cases were disclosed in Brooklyn alone, with a mont, an outbreak of polio was reported in 1894 which took the lives of mortality rate of about 20 percent. Before it was all over in November, 132 people before striking New York in 1907 and killing an estimated New York City reported a total of 8,927 true cases of polio and 2,343 2,500 persons. After 1907 polio epidemics became increasingly more deaths, with the two less-populous boroughs, Richmond and Queens, frequent. Between 1910 and 1914 alone about five thousand deaths and actually showing the highest case rates. Nearly half of the victims- thirty thousand cases were reported in the United States.⁷¹ 4,500, were seen in or admitted to the city's hospitals. Nationwide, the As in previous instances, human actions contributed decisively to poliomyelitis epidemic of 1916 affected 27,000 people in 26 states and the creation of a favorable ecological setting for poliomyelitis. Iron- caused about 6,000 deaths.⁷ ically, the culprits were improved public sanitation and personal hy- One of the first tasks of the New York Health Department was to giene, slowly achieved after decades of cholera and typhoid fever. Such ascertain the dimensions and geographic contours of the new epidemic, relative cleanliness presumably reduced the transmission of wild and a coordinated process based on numerous field reports provided by an ubiquitous polioviruses that had hitherto routinely infected most in- army of inspectors and nurses. As one publication stated: "It is the fants and young children without producing paralytic complications. health officer's task in an epidemic to know where all cases are in his As a consequence, these groups became increasingly unprotected and bailiwick. Detection and disclosure of new cases was paramount to susceptible to the crippling form of disease. In fact, many children be- achieving control of the epidemic, and it could only be carried out with came polio victims soon after being weaned and thus deprived of ma- the help of the medical profession and the public. Neighborhood health ternal immunity.72 stations were at the forefront of these search-and-report missions. Some Ever since poliomyelitis had become a reportable disease in 1910, infants brought in for regular visits could not hold on to their bottles. HUMAN SERVICES. USA HEALTH& DEPARTMENT OF HEALTH & HUMAN SERVICES Public Health Service OF DIRECTMENT National Institutes of Health Bethesda, Maryland 20892 Building : 31 Room : (301) 496- 7A03 2263 March 7, 1990 Mr. Robert Simon The White House. Old Executive Office Building Washington, DC 20500 Dear Mr. Simon: As per our recent telephone conversation, I am enclosing an outline for my presentation at the National Leadership Coalition on AIDS, which will be held at the Crystal City Gateway Marriott on March 29. In addition, I have enclosed an article which I recently wrote entitled "AIDS: The Challenge to Biomedical Research." I hope that you find these materials useful. If I can be of any further assistance, please feel free to contact me. Thank you and best personal regards. Sincerely, Anthony S. Fauci, M.D. Director National Institute of Allergy and Infectious Diseases ASF:1r Enclosures Brief Summary of Presentation Anthony S. Fauci, M.D. As we enter the 1990s, the number of reported cases of AIDS continues to mount and the urgency to develop effective strategies to prevent and control HIV infection becomes more pronounced. The United States Public Health Service estimates that by the end of 1992 there will be approximately 365,000 cumulative cases of AIDS in this country, with close to 263,000 cumulative deaths. Yet there is reason for cautious optimism that the shape of the epidemic can be changed. From a scientific perspective, progress in understanding this disease process has moved forward at an impressive rate. The fundamental manifestations of the disease have been documented and the general contours of the epidemic delineated. Basic research efforts have led to the discovery of the causative agent (HIV), as well as insights into the targets for the virus in the body, the body's responses to infection with the virus, and the pathogenic mechanisms whereby the virus produces its deadly effects. A nation-wide clinical trials program has been established to test experimental AIDS therapies, and several trials of potential AIDS vaccine candidates are currently underway. While a cure for AIDS or a vaccine against HIV infection remains elusive, steady progress in survival and in the quality of life for HIV infected individuals is being achieved. As scientific advances offer many more options for treating HIV infected individuals more effectively and earlier in the course of disease, HIV infection is coming to be seen as a potentially chronic, manageable disease. In his presentation, Dr. Anthony S. Fauci will review important accomplishments and the current status of biomedical AIDS research efforts. With an eye towards the many challenges HIV infection/AIDS will present for the 1990's, Dr. Fauci will focus on the promising new avenues for scientific pursuit and, importantly, the prospects for therapeutic intervention. Outline of Dr. Anthony S. Fauci's Speech to the National Leadership Coalition on AIDS March 29, 1990 Crystal City Gateway Marriott Hotel Crystal City, Virginia AIDS: Considerations for the 1990s I. Issues for the 1990s: A. The changing profile of the HIV epidemic B. Basic research C. Therapeutic intervention D. Vaccine development E. Special considerations for the 1990s II. The changing profile of the epidemic: In the 1990s we can expect an even greater concentration of new HIV infection among IV drug abusers, particularly in the inner city areas. This will lead to a situation in which there will be a disproportionatly greater burden of HIV infection among minority populations. Since an IV drug using population will be the major target of new infections in 1990s, by definition this will lead to a greater number of heterosexually transmitted cases, cases among women, as well as HIV infection among newborns. At the same time as the rate of infection will increase in IV drug users, there will very likely be a decrease in new infections among homosexual and bisexual men. Nonetheless, there will still be large numbers of homosexual men who are already infected who will become sick in the 1990s. III. Basic research: New opportunities in basic biomedical research regarding HIV infection will be discussed. IV. Therapeutic intervention: A. Drug development B. Clinical trials C. Early intervention: A greater emphasis has already been placed on treating individuals who are HIV infected who have not yet developed symptoms or those who have very few symptoms. Most recently in the summer of 1989 a number of clinical trials have indicated that at least one drug (AZT) is beneficial in delaying the onset of symptoms in individuals early on in their infections. This has already led to a philosophy which will be further realized in the 1990s of early intervention of HIV infection. D. Access to therapy: The Public Health Service is already implementing a mechanism for expanded access to therapy simultaneous with the conduct of clinical trials. V. Advances in vaccine development: Over the past year there have been a number of important advances in the development of vaccines for HIV infection. Of note is the fact that in at least three separate studies in an animal model (monkey) of AIDS there have been clear-cut indications that a vaccination with the whole killed monkey virus can lead to protection against challenge with the live virus. This has important implications for the possible development of a vaccine for HIV in humans in the 1990s. VI. Special considerations for the 1990s: The large numbers of individuals who have been infected with HIV have brought into focus a number of important problems in society which must be addressed, including the widespread use of drugs in society and the lack of adequate health care services for a number of segments of society. 119369 0 P Y STATE 8 A UNITED TROOI from ORM SEAL Feb.16,1990 Aboard Air Force One Dear Steven, Leonard, Ray, John, Chris, Joseph a William - I read and re-read touching letter of your Feb. 6 the - so did Banbara. we do care and we learned from our visit mth you - we learned lot about courage a and also a lot about hope May T hands for your letter Good Luch and Over hs Bul 900221 Mr. Stephen Welch and Friends Department of Health & Human Services cool Public Health Service National Institutes of Health Building 10, Room 11C442 Bethesda, Maryland 20892 w2 are thing to Maine to see our dauplite but 2 wanted to send my lowe also. us do look you and worry about you. Zarbara Buse Mr. Stephen Welch and Friends Department of Health & Human Services Public Health Service National Institutes of Health Building 10, Room 11C442 Bethesda, Maryland 20892 THIS IS A BEAUTIFUL LETTER. TO SHIRLEY GREEN'S OFFICE TO MAIL OUT. SERVIC see attached ID 101953 HEALTH DEPARTMENT OF HEALTH & HUMAN SERVICES Public Health Service 3 National Institutes of Health Bethesda, Maryland 20892 Building : 10 Room : 11B-13 (301) 496- 7196 February 6, 1990 President Bush White House Washington, D.C. 20500 Dear Mr. President: Two days before Christmas Eve, in the midst of what must have been an extremely taxing and exhausting week for you, with the situation in Panama demanding your attention and leadership, you took the time to meet with seven of us, living with HIV infection, on the 11th floor clinic of the National Institutes of Health. What a gift you gave each of us that day. Living with AIDS and HIV infection can be like living in a world without hope. The only ultimate truth that we know about living with AIDS is that in time, it has the potential to devastate us. In the meantime, each of us looks for hope in very personal ways. We seek comfort and warmth from those that we love. We seek new answers through participation in experimental drug studies. We seek to enjoy the simplest of pleasures in everyday life. We seek to make peace with ourselves and those who don't understand us. We seek a voice, a compassionate voice that can address the concerns of hundreds of thousands of people that will die from a disease that we have discovered does not discriminate. That is the gift that you gave us on the Friday of your visit. You have given us hope of a strong voice and leadership in the area of AIDS research and education, and of continued compassion and concern as America learns to live with people living with AIDS. From our hearts our thanks to you and Mrs. Bush for a gift that we will hold dear all the days of our lives. Sincerely, Hephey Well CEShipherd Stephen Welch Chris Shepherd Joseph Smith Leonard Jackson Joseph Smith Ray by all Ray yall John Rooney John Rooney William William Talley Jalley George Bush for President CONTACT: ALIXE GLEN (202) 842-1988 FOR IMMEDIATE RELEASE CONTACT: 202/456-6772 Monday, June 1, 1987 REMARKS FOR VICE PRESIDENT GEORGE BUSH THIRD INTERNATIONAL CONFERENCE ON AIDS WASHINGTON D.C. MONDAY, JUNE 1, 1987 now It is truly an honor to address this distinguished group today. And I want to offer my sincere thanks to the Department of Health and Human Services and the World Health Organization for their work in making this conference possible. Coming as you do from around the globe, united in purpose, what you accomplish here is of vital importance to every nation on earth. It is no exaggeration to say that the health and well- for being of literally millions of men and women depend on you. The cause that unites us, of course, is our battle against AIDS, a new and mysterious disease. The number of victims is almost doubling every year. As of a year ago the United States had a total of 16,000 cases of AIDS reported since 1981. Today that total is over 36,000. Over one-half of those victims have died of the disease. And the tragedy is that the rest may, too. By this time next year we will have added more than 23,000 new cases of AIDS. And by the end of 1990, the U.S. Public Health Service predicts a quarter of a million Americans will have contracted AIDS. When we in the United States first began to confront the AIDS epidemic six years ago, the victims were easily categorized. There were the homosexuals, the bisexual men, the I.V. drug users, and the recipients of blood and blood products. And these groups still account for 9 out of every 10 cases here in the United States. But now we're receiving more and more reports of the AIDS virus infecting heterosexual men and women who are not I.V. drug users. In fact, their heterosexual activity seems to be their only risk factor. Close to four percent of all reported AIDS cases in this country are reported to result from heterosexual contact. 733 15TH STREET, N.W., SUITE 800, WASHINGTON, D.C. 20005 TELEPHONE: (202) 842-1988 Paid for by George Bush for President 2 On the face of it, four percent does not seem like much. But that number is expected to increase dramatically during the next five years. It is projected that by 1991, most people in certain cities in America will know someone who died of AIDS. in every corner of the world. It does not discriminate. It is an So make no mistake about it. AIDS is spreading and killing, equal opportunity merchant of death. Cases of AIDS have been reported in 112 countries. The World Health Organization estimates that as many as 100 million people will become infected with AIDS during the next decade. As if these figures are not appalling enough, there is more. A large number of individuals who do not knowingly practice high-risk behavior are also being infected by the AIDS virus -- people like the wives of bisexual men, the spouses of I.V. drug users, and the husbands and wives of promiscuous spouses, and, saddest of all, babies born to I.V. drug users or otherwise infected mothers. Tragically, some infants are being abandoned, left to die alone in hospital nurseries. susiness What can be done to help? Well, first and foremost we desperately need a cure or a vaccine. I chair the President's Task Force on Regulatory Relief and earlier this year we worked with the Food and Drug Administration to accelerate the availability of experimental drugs to AIDS patients. We did this to encourage more research and development on potential AIDS vaccines by the private sector. Meanwhile, our government will spend $766 million this year and close to $1 billion next year on AIDS. And as we look into the 1990's we may have to spend even more. But money alone won't stop AIDS. Those at high risk must be educated on how to avoid contracting the disease. The only guaranteed way to halt the spread of AIDS, given what we know now, is a change of behavior. And those at risk will not change unless they know the terrible dangers they face. As a world community, we have a tradition of taking a straight-forward approach to health warnings. When, through careful scientific research, a health hazard is identified, warnings are issued by health officials, and most people take steps to reduce their risk to disease or danger. -more- 3 Research, warning, risk reduction -- three phases that have served us well in the past, and must continue to serve us well in combatting the AIDS crisis. If we know that dirty needles and certain kinds of sexual behavior can transmit AIDS, we have an obligation to make the public aware of the risks involved. = am not a scientist or a researcher or a medical doctor. But as an elected official, I think an important role of the federal government is to provide timely, factual, and impartial information about this deadly, insidious disease. I have spoken with the Secretary of Health and Human Services, Dr. Bower, Surgeon General Koop, and many others about the possibilities of finding a cure or a vaccine as soon as possible. And I applaud the efforts they've made to educate the American people about AIDS. In April, I toured the research facilities at the National Institutes of Health. I visited an AIDS patient, and talked to him about what he was going through. I saw firsthand what this disease can do. It is brutal. It is unforgiving. We must wage an all-out war against the disease. Let me repeat: an all-out war against the disease -- not against people. Not against the victims of AIDS, but an all-out war against the disease itself. The most important thing we can do is to tell our people the facts about AIDS and what they can do to protect themselves from it and to prevent it from spreading any further. We've got to put into the hands of parents and students and people throughout America essential facts about AIDS in a thoughtful, sensitive manner. I recognize some of the countries represented here have already successfully completed nationwide mailings. I hope we can learn from your experience and find creative ways to distribute some of the very good material that has been developed. I believe that education is primarily a local matter. Parents and the community should control what goes on in their schools. That system has worked well for more than 200 years and I don't want to change it. I don't want the Federal government to mandate some insensitive educational program. Most schools now offer some kind of sex education during the junior high or middle school years. Depending on local standards and after a meeting of the minds with parents and school officials, education about AIDS should be incorporated into the curriculum. If the curriculum is well-planned and thoughtfully -more- 4 carried out, we can teach children the facts about sexually transmitted diseases -- and AIDS in particular. This kind of education can and should be non-threatening. It should teach traditional values. It should teach morality. It should help develop the child's own sense of personal responsibility. And it should strengthen the concept of the family. When it comes to educating our young people about AIDS, we must all work together -- parents, educators, religious and community leaders, medical doctors and scientists. As difficult or as awkward as it may seem, parents must assume much of the responsibility for educating their children about AIDS. They need to talk to their children in a way that only a parent can -- with a special love, compassion, respect, and understanding. Not long ago, my wife Barbara and I received a telephone call from our second oldest son, Jeb. He was concerned about the threat of AIDS and how to explain to his children the dangers of this terrible disease. It seems that Jeb's 11-year-old son, Barbara's and my grandson, had come home from school one day asking about AIDS. That really brought home to me the absolute necessity of educating our young people. Right now, education is our best weapon against this dreadful disease. In some respects, education is our only weapon. And let me repeat again the crux of our battle. It is a battle against a disease and not against people. We must remember that the sick and the dying require our care and our compassion, no matter how the illness was contracted. Which brings us to perhaps the most controversial subject in dealing with AIDS: testing. Who should be tested? This issue raises some difficult and troublesome questions for me. It puts in conflict the need for more information and knowledge to benefit the majority versus our basic Constitutional right to privacy. We have often had these questions where two of our basic rights or needs come into conflict. We use our political process and our government to resolve these conflicting interests. Testing is an extremely complex issue for that very reason. But it is the responsibility of the political leadership to decide among competing principles. Ultimately, we must protect those who do not have the disease. -more- 5 Thus, we have made the decision that there must be more testing. As the President said last night, the federal government will soon require testing for prisoners, immigrants and aliens seeking permanent residence. Tests are already being conducted in the military and in the foreign service. Additionally, we are encouraging the states to offer routine testing for those who seek marriage licenses and for those who visit sexually transmitted disease or drug abuse clinics. We are also encouraging states to require routine testing in state and local prisons. Of course, any mention of testing must be hurriedly followed by the word, "confidentiality." If society feels compelled, in some circumstances, to test its citizens, then it is absolutely imperative that those records are kept appropriately confidential. It is also imperative that help be available to those who test positive. In closing, let me say we need money for research and treatment. We need education. We need testing, but only accompanied by quarantees that everyone is treated fairly. We all have a duty -- and I don't use that word loosely. Elected officials must use their position as a bully pulpit to get out our message about the dangers of AIDS. And the experts -- all of you -- the doctors and the researchers who deal with this disease on a daily basis must not let up until a cure is found. Although our respective roles are different, we do share one common responsibility. And that is to remain understanding, caring and compassionate toward those afflicted with AIDS. We must not succumb to the demagoguery or the irrational ideas of some out there. The fight against AIDS is not a partisan fight. It is not a witch hunt. It is our duty to do all we can not only to find a cure and a vaccine, but also to make sure we never create a climate in America, or in any other country, where friend turns against friend, where countryman turns against countryman. All of you here today are working toward a common goal, a common purpose that pits mankind, with all of our genius and expertise, all of our high technology and laboratories, and all of our great educational institutions against a microscopic virus that has declared war against our bodies. The challenge is upon us. And it is a challenge we must meet. Good luck to all of you. I hope you have a tremendously productive and fruitful conference. We're counting on you. # # FROM: Hans Kuttner Two audiences: GB on the record on AIDS: Presidential leadership for compassion. Business and other institutional executives who have come to the conference to decide if this is something they have to worry about. Significance of the NLC speech Marks the transition of AIDS from being new and different to being an ordinary part of the fabric of American life. - More and more infected people will experience HIV infection as a long-term, chronic disease. - And this requires thinking about the disease in our institutions' and our society's long term. Key fact of this stage: AIDS is not going away anytime soon. It will be a chronic condition of society and individuals afflicted. Take Away Line for Firms AIDS isn't a one-time crisis. It is something more and more firms can expect to experience, either through an employee or family member of an employee. You need to be ready. Cancer Analogy O We have to face AIDS just like we did with cancer a decade ago. Once we were threatened by cancer. No longer. Need a sense of compassion so that those who suffer, either personally or as family members, do not feel alone. Leadership at all levels President: Asking Americans to show their best instincts -- be compassionate and caring. - American people are responding in the traditional American way: they are being compassionate. - This is another opportunity to help people in need. [pts of light] In our communities: Having a response proportional to the problem. San Francisco, itself a thousand points of light in response to the AIDS epidemic there, shows what can be accomplished when those lights shine. The volunteers who provide so much community-based care make it possible for cost per AIDS victim to be substantially lower than in other high incidence cities like New York or Los Angeles. Communities must come together; a thousand points of light isn't a frill, its a necessity. In our workplaces: Letting co-workers know they are safe when someone with HIV works nearby. 03: 13. 90 10:10 AM * IMMED. OFFICE ASH P02 FROM: HHS Dr. asst Mason's Sec. for office Health DRAFT Draft Talking Points President's Presentation to the Business Leaders Forum on AIDS March 29, 1990 POLIO Welcome Opening, Capsule summary of the AIDS epidemic as a problem without precedent in our time. We have had numerous other epidemics of infectious diseases, but this problem at this point in our history is unique -- and it demands a unique response from all of us. It is important to focus not just on AIDS but on HIV, the virus that causes AIDS, since people become infected long before they develop symptoms and become 111. Acknowledge role of business in the fight against AIDS. Thank business leaders who have been involved to date for the work they have done. Cite examples of the efforts and programs that business and labor have developed. Reiterate that unlike many of the diseases that strike our elderly population and cause disability or chronic illness, AIDS affects primarily people in the prime of life -- those who are in the labor force or being groomed for the corporate structure. More than 115,000 persons in the U.S. with AIDS, 95% of the total reported, are in people aged 20-59. Many more adults who are infected are in the work force now, and it is essential to have more involvement of the business community in addressing the issues that will be raised and developing the programs that will be needed. The AIDS epidemic is not over. Dr. Curran has presented information this morning about the trends of the epidemic. We can all be encouraged that current projections suggest that the numbers will not be as large as we thought just a year ago. But the epidemic is not over. We have lived with AIDS for almost a decade. It took almost 2 years to diagnose and report the first thousand cases. It took another 3 years to report the first 10,000 cases. In the last 12 months we had more than 36,600 cases reported from our States and territories. It is predicted that even more cases will be diagnosed during the next 12 months and on into the decade of the nineties. 03213.90 10:10 AM *IMMED. OFFICE ASH P03 DRAFT Page 2 -- Draft Talking Points A few cities and States have been particularly hard hit, with thousands -- or even tens of thousands of cases reported -- but there is no area of our country that has not been affected to at least some degree. We all must be involved. None of us can afford to say that AIDS is not our problem. In particular, the response of the business community is critical because you work with and employ so many of those who are already infected and who will become ill in the future; those who may be at risk because of behavior choices they make and who need the information to reduce their risk; and those who will be concerned about whether it is safe or proper to become involved or to extend a helping hand. Employees trust and act on information provided by their company and their boss. You in business are in a unique position to influence the response of this country to the AIDS epidemic in the decade ahead. We need an educated population to prepare for the future -- and for adults, education in the workplace and by example is the best answer. The AIDS epidemic is having a major impact on our society and our health care system. We have a unique health-care system in the U.S. that has developed the most sophisticated care available in the world. It is a system that is built on a diversity of patterns of care and sources of support. Business and the business-related health insurance programs have been an integral facet of that system. No system is without problems, however. AIDS has magnified some of the weaknesses and flaws in our system, particularly that of equity of access. In my State of the Union Message in January, I asked Dr. Louis Sullivan, my Secretary of HHS -- who has already spoken to you -- to lead a Cabinet-level working group t address this issue. Last year, Dr. Sullivan formed a task force in HHS to address a similar set of issues. It will not be easy, but we are making progress on this front. Business also will be a part of the answer, because as we develop more effective therapies for people with HIV infection and AIDS -- therapies that delay or prevent many of the complications and the progression of the disease -- we will be able to keep people in the workplace and functioning normally. They will continue to be productive members of our society. Business has a real interest in seeing this come true. 03. 13. 90 10:10 AM * IMMED. OFFICE ASH P04 DRAFT Page 3 -- Draft Talking Points We have other pieces of the puzzle that need to be put in place also. We still need to solve the problem of discrimination against people with AIDS. I support -- my administration supports -- the Americans with Disabilities Act that was passed by the Senate last year. We need to see it passed by the House this year. This type of broad-based legislation was strongly recommended by Admiral James Watkins and the Presidential Commission on the HIV Epidemic that he chaired. [Acknowledge Secretary Watkins, who should be in the audience, and Dr. Burton Lee, also a member of the Presidential Commission]. O Closing, In closing, I want to reiterate that this epidemic is important and that our response to it is important. The leaders of the National Commission on AIDS have been keeping me informed about the progress that they have been making. I am asking them as part of the work that they do to meet with leaders of the business community and together to explore and recommend ways in which business can address this epidemic and our response to it. We all must work together and pledge our commitment to stop the spread of new infections through education and behavior change, and to provide the support and services needed by those who are already infected and their families. Together, we can make a difference! OVERVIEW ON AIDS AIDS was recognized as a discrete disease in 1981. Since that time the size and scope of the epidemic has grown rapidly. As of November 1989, 115,158 AIDS cases have been reported to the Centers for Disease Control, including 1,947 cases in children less than 13 years of age. of this number 68,441 of the reported individuals have died, including 1,059 children. Based on current projections, there are approximately 1 million people in the U.S. infected with HIV. Data available suggest that by 1992 the cumulative number of diagnosed AIDS cases will be 365,000 with nearly 263,000 cumulative deaths. The Federal Government has played a major role in addressing HIV infection and AIDS since the disease was identified in 1981. In fiscal year 1989, total Federal spending for HIV/AIDS was $2.25 billion, with HHS receiving $1.98 billion (88% of total Federal AIDS budget), and the PHS receiving $1.29 billion (57% of total Federal AIDS budget) (Budget table attached). DEPARTMENTAL ACTIVITIES The Departmental components with major HIV/AIDS activities and responsibilities are: Within PHS: : The Alcohol, Drug Abuse and Mental Health Administration (ADAMHA) supports research on neurological and behavioral aspects of HIV/AIDS and intravenous drug abuse. -- The Centers for Disease Control (CDC) supports surveillance, epidemiologic studies, monitoring of trends, and public information and education, including efforts to target High- risk groups. The CDC-supported National AIDS Information Clearinghouse mails nearly 1 million pieces of HIV/AIDS information per week. The Food and Drug Administration (FDA) provides for evaluation and approval of new drugs and vaccines that proved safe and effective against HIV infection and clinical manifestations of AIDS and assures the safety of the blood supply. The Health Resources and Services Administration (HRSA) supports 20 AIDS service demonstration projects designed to provide innovative ways of providing care to AIDS patients. In addition HRSA, in conjunction with NIH, established 13 pediatric AIDS demonstration centers to develop community- based, family centered care for AIDS infants and their families. 12. 21. 89 01:18PM *DHHS/IOS 245-7591 PO3 The Indian Health Service (IHS) provides AIDS related services and health care for American Indian and Alaskan Native populations in the United States. The National Institutes of Health (NIH) supports basic, applied, preclinical and clinical research efforts. Principal activities include research on the virology of HIV and its variants, natural history of the disease, AIDS drug discovery and design, clinical trials, vaccine development, training for health professionals and international research. Currently, the NIH supports 35 Clinical Trials Units, 16 Drug Discovery Groups, 6 Vaccine Evaluation Units. Within HHS: : The Health Care Financing Administration (HCFA) funds direct treatment costs for AIDS patients through its Medicaid and Medicare Programs. The Social Security Administration (SSA) provides cash assistance to individuals with HIV-related illinesses through Disability Insurance and Supplementary Security Income programs. The Office of Human Development Service Administration (OHDS) funds foster care demonstration grants to states to address the problems of HIV-infected infants who are abandoned at hospitals. INTERNATIONAL ACTIVITIES Because HIV/AIDS is a global issue, the Department has worked with relevant agencies to coordinate international efforts directed toward epidemiology, prevention, treatment and information sharing. Various PHS agencies along with the Office of International Health have worked with the U.S. Agency for International Development, Department of State, The Pan American Health Organization, and the World Health Organization's AIDS-related efforts. In addition, the U.S. has entered into bilateral agreements with countries such as the U.S.S.R., Japan, France, India, West Germany and Thailand. SOI/SHHG* 01:19:10 68 21. 121 PO4 ID 0 A Total Federal Government Spending HIV/AIDS (dollars in millions) 1902 1983 1984 1985 1906 1987 1988 1989 1990 Change 89:90 Public Health Service $6 $29 $61 $109 $234 $502 $962 $1,289 $1,582 +$293 (+23%) Medicaid (Federal share) 1 10 30 70 130 200 330 490 670 +160 (+37%) 1 2. 12. 2 21. 1. 8 9 0 1 : 1 8 P * D H H S / I 0 *DHHS/IOS S = 4 5 7 5 9 1 Other HHS 1 1 6 18 38 3 106 199 825 +126 (+63) Subtotal, HHS a 39 Q7 197 402 707 1,398 1,978 2,577 +502 (+30) Veterans Administration 2 5 7 11 23 56 64 142 179 +37 (+26%) Defense Department - I - - 79 74 53 96 107 +21 (+24) Agency for International Dav. - 1 - - 2 17 30 :40 41 +1 (+3%) Other Federal Government - { 1 - 1 3 4 5 8 +3 (+60%) Total, Federal Spending a 44 104 209 507 910 1,569 2,251 2,912 +661 (+29%) phs:214e AIDS UPDATE Key PHS Accomplishments: 1981 - Recognized AIDS as a new disease. 1982 - Established that the disease was spread through sexual intercourse and transfusions of contaminated blood, sharing of needles by drug abusers and from an infected mother to her baby during pregnancy or at the time of birth. - Developed the first of numerous guidelines to protect the public against infection in the workplace, schools, and the community at large and to let them know that the disease is not spread by casual concact WHEN a.. infected individual. 1983 - Established a toll-free national AIDS hotline. 1984 - Identified human immunodeficiency virus (HIV) as the cause of AIDS. 1985 - Licensed HIV antibody blood tost which allowed blood to be screened, greatly improving the safety of the blood supply. 1986 - Established an HIV prevention program in every State. 1987 - Approved in record time & new drug application for one significant drug therapy - Azidothymidine (AZT). - Initiated testing of two experimental AIDS vaccines in human volunteers. - Established the National AIDS Information Clearinghouse. 1988 - Distributed 107 million copies of Understanding AIDS, an educational booklet, to every household in the United States. - Greatly expanded the existing national network of centers conducting the clinical trials of promising new drugs for the treatment of AIDS and HIV infection. 1989 - Third wave of "America Responds to AIDS" public education campaign is initiated. - Approved Aerosol Pentamidine as a treatment against Pneumocystis carinii pneumonia and issued guidelines for use as a prophylactic agent. POB 1SSL-S SOI/SHHG* 68 21. 12. THE WHITE HOUSE WASHINGTON Date: To: NOTE. -- - POTUS has not yet of this seen. Office Beverly is currently Ward preparing a draft for his signature. TERESA DONOVAN Presidential Correspondence Office Room 94, x7610 March 1, 1990 President George Bush The White House Washington, D.C. 20500 Dear Mr. President: We are writing as members of the Mayor's HIV Task Force in San Francisco and as religious leaders who are deeply concerned about our community. As you know, the AIDS epidemic has taken an extraordinary toll on our city. AIDS has already claimed more San ? Franciscans than all the wars in this century -- World War I, II, Korea and Vietnam -- combined and tripled. Our response to this crisis has been a model for the nation. Individuals, businesses, health care workers, churches and synagogues have built a compassionate system of care and support which has helped people with AIDS live with dignity and receive quality medical care. The message we must deliver today is that this system of support and care is crumbling. Even with renewed commitments from each of us, our community will need more help from outside sources to keep up with growing caseloads and skyrocketing costs of health care and services. For all the suffering and sacrifice that the epidemic has brought us, we know that more people will live and die with AIDS in the next decade than did in the last. What is needed is direct aid to communities like ours which have been hardest hit by the epidemic. We need immediate help just to provide basic services: housing for those who are ill with no place to go, medical care to prolong the productive lives of those infected with the HIV virus, and outpatient services which reduce costly and unwanted hospital stays. The AIDS epidemic tests our willingness to define the word "community" in its broadest sense. AIDS is not a problem of one neighborhood, city or sector of our society. All of us are affected and all of us must respond. We urge you to actively support legislation which would provide substantial additional assistance to communities most profoundly affected by the AIDS epidemic. Thank you for your attention to this urgent concern. Sincerely, Robert Kirscher Dr. Robert Kirschner, Rabbi Temple Emanu-el P.O. Box 18247 San Francisco, CA 94118 Most Reverend R. Quinn + Jmn R.Jurin John Archbishop of San Francisco 445 Church Street San Francisco, CA 94114 + William E. Sing Rt. Reverend William E. Swing Episcopal Bishop of California 1055 Taylor Street San Francisco, CA 94108 my ng editor of The Jewish Daily Pierce Corson of the Philader- Responsibuity Mission Society in A special phia Methodist Area. and Ralph Mrs. Frank Higgins. a Chicago and Bishop Raymond A. Lane, su- be conducted at 11 A. M. tomor- Memoeller, German Protestant WS. policewoman who 13 director of the n 1928 when the latter paper G. Luff. president of the Ocean perior general of the Maryknoll row at the Broome Street Taber- eader, said tonight he believed the 3 merged with The Jewish Chicago Crime Prevention Bureau, Missioners. nacle. 395 Broome Street. The Flussian church would participate City Tabernacle Association, will conduct panel sessions on rning Journal, Mr. Danzis joined Rev. Gustavo Verdesi will preach. in a world-wide Christian unity staff of The Day. of which he Ocean City, N. J. will visit "Family and Youth." Other Sea- School Plans Sessions Here The Rev. Dr. Theodore Cuyler movement if permitted by the came editor in 1950. He served Heidelberg. Germany. soon to stons will be devoted to Carl Scout- Speers will interrupt his vacation Kremlin to do SO. Dr. Niemoeller this capacity until 1952. when confer with Army chaplains and mg. mission work. scholarships, The Summer School of Catholic to preach from his pulpit at 11 recently visited Moscow. became an editorial staff mem- officers on occupation problems. activities on behalf of the blind Action. which has scheduled its A. M. tomorrow at the Central and the federation's educational Before going to Germany, New York City sessions for Aug. Presbyterian Church, Park Ave- r. He was a former vice president Bishop Corson. who 13 president and Internary projects. nue and Sixty-fourth Street. His DDT SPRAYED ON RAHWAY 18 to 23 at Fordham University, the Jewish Writers Club (Peretz of the Council of Bishops of the Cardinal Spellman will speak at has 83 its theme this year "God's topic will be "Mid-Summer's grein). Mr. Danzis had traveled a dinner at 15 P. M. Thursday. Methodist Church, will preach in Law the Measure of Man's Con- Dream." Drive Against Insects Conducted tensively in Europe. Asia and Wesley's Chapel. Mother Church Other speakers will be John F. Inct The school, which was as Anti-Polio Measure itin America. and had made Breanan of the State Board of of Methodism, London, on Aug. started in 1931. has traveled 120,- Christian Science Services ree trips to Israel, publishing ac- 24. At. the end of the month. the Regenta and Mrs. James Sheeran (100 miles and currently has Special 10 THE NEW YORK TIMES. unts of his travels in Yiddish. church representatives will go of Mineola, 1. 1. a co-founder of twenty-five lay and clerical in- The topic of the Lesson-Sermon RAHWAY, N. J., Aug. 15- Surviving are his widow; a son, to Stuttgart. Germany. as fra- the federation Mrs James F insurators on a trip of 8,000 miles, in Christian Science churches tc- Manned by a Union County Mos- dney: a daughter. Mrs. Helen Looram of Elmhurst. Queens, it sping at ten cities for the morrow will be "Soul." The Golden quito Exterminating Commission ternal measengers to the Kirch- haikin. and a grandson. entag Assembly of all German chairman of the federation's Text is: "I have longed for Thy crew, a spray truck today started servions, Protestants, and also to Zurich, partment of mothen pictures, will With the completion of this salvation, () Lord: and Thy law :3 "fogging" DDT throughout this ASKELL BEARERS NAMED Switzerland, to address Meth- introduce the speakers. year schedule, cities my delight. Let my soul live, and city in an attempt to combat in- odist hering will have been visited. including it shall praise Thee: and let Thy fantile paralysis, which killed Bishop Corson will lease from Catholle Students to Meet in Canada. A group of courses judgments help me." (Ps. 113 three persons here in a month. oover, Dewey and Lehman New York International Airport, will end in Boston today. and the 174, 175.) The spraying started in the Listed for Rites at West Point Dillewid, Queens, on Tueaday from The of fifteenth the Catholic national Students MIA tenth group will be given Aug 25 convents Whittier Street-Koening Place sec- and will he joined in London by don Crusade will be held Aug 21. to 20 in Chicago The key speaker Archbishop Makary Elevated tion, where there have been five Special to THE New York TIMES Mr. Luff. 21 at the University of Notre in all the cities has been the Rev. cases of the disease. ALBANY. Aug. 15 Former Dame, In Notre Dame near South Dannet A Lord, editor of "The Archbishop Makary of New The operation. authorized by the resident Herbert Hoover and Rend. Ind. with 2000 delegates Queen Work," published in St York, exarch of the Moscow P1. Rahway Common Council as a AID SOUGHT FOR CHINESE peeted Among the on the Locat An estimated 140,000 stu- triarchate since 1948. has been step toward eliminating a possible mor Dewey will be honorary pall- earers tomorrow at the funeral agenda 11 table forum, will have attended the elevated to be Metropolitan of the cause of polio through the killing Patriarchal Russian Orthodox of flies. mosquitoes and other in- I Lieut. Gen. William N. Haskell, U. S. Group Wants $1,000,000 to with representatives of the tech this year. Church in the Aleutian Islands a.- sects, should be completed by to- nical assistance agencies of the ormer Commanding General of the Help 20,000 in Hong Kong North America The vice-exarch morrow. a County Mosquito Com- United States Government and the Humanists to Meet few York National Guard. Archbishop Adam, who return mission spokesman said. Other honorary bearers will be Twenty thousand Chinese Intel United Nations participating Es-man Catholick The first international congress this week after a six-week trip :: Mayor James E. Egolf said to- lenator Herbert H. Lehman, Lieut. lectuals who have sought refuge prelates Among to the speak will be Arch on humanum and ethical culture Moseow by air to give an official day that the commission had agreed in Hong Kong are being woold by bishop Karl Affer Cincinnati, will be held Aug 21 to 26 111 Am- routine report. NYT to do the job without charge. len. Willis D. Crittenberger, com- handing General of the First the Communists to bring their skills back to their homeland. an Army: Lieut. Gen Robert C. Rich- American back from the British ardson Jr, retired: Maj. Gen. Karl RELIGIOUS 8-16-52 colony declared yeaterday He 13- i. Hausauer, chief of staff to the serted that they should be anded lovernor and Commanding General DIVINE SCIENCE PRESBYTERIAN PROTESTANT EPISCOPAL by the Allies 113 they a tremen- ABSOLUTE SCIENCE if the New York National Guard: dous resource against communism DIVINE UNITY firam C. Todd. Alvin E. Blomquist in Asia. (ABSOLUTE SCIENCE) REV HELEN ZAGAT and Duncan G Harris of New The Brick Church Cathedral Harold L. Oram. special repre- HEAR DR. JOSEPH LARSON Herital Hall 154 57th It. the Divine services Required Sept. 3 Park Avenue 91st Street York. and Richard K. Mellon of sentative of And Refugee Intelled- Pet Plaza 1400 THE REV PAUL WOLKE. D D Minister R 9. & 11 (Morn Prayer &), Holy Communion Ligonier. Pa. 11 A M -DR MILLARD C ROBERTS tuals, Inc. which 14 headed by "Fruit Out of Season Isa Mellwraith. Organial 10. Morning Prayer 4, Evensong Also Lieut. Gen. Cornelius W. Preacher at 11 and 4 Representative Walter H Judd. Church illie Truth The Rev Stanley A. H. Eley Wickersham, retired: Maj. Gen. Broadway Presbyterian Prebendary of St. Paul London returned Thursday after surveying Weekdays 15. 8 (and Wednesday 10). Howard McC. Snyder, retired: Brig. the possibilities of bringing them Broadway at 111th Street Cathedral Tours: Sundays. 12:30 and 5 Gen. Troup Miller: Maj. Gens. John BAHAT WORLD FAITH DR. ERVIN SEALE DR JOHN 11 McCOMB Minister Weekdays. 11. 12, 2. 3, 4 K. Herr and Frank P. Lahm. re- help. REV WILLIAM McLEISTER Guest Preacher Minister Pastor. Mount Lebanon Mr. Oram said his organization 119 tired: Brig Gens. William H. Kelly, ENGINEERING AUDITORIUM United Presbyterian Church. Pittsburgh. PL ST. JAMES' Madison Ave. at 71st Street would try to raise $1,000,000 to- SUNDAY. West PRINTST that sen and Bill 11 A M AND 8 P Wed., 8:15 P M -MR MOLEISTER Rev ARTHUR LEE KINSOLVING. D.D., Rector Charles E. Saltzman. Hampton An- ward this end in a nation-wide HARRY JEFFRIES Prayer and Bible Hour 8. Holy Communion 11. Morning Prayer derson and Gerard W. Kelley and HAHAT IN Sermon at 11: The Rev. James F. Martin campaign this fall. He said his Speaker RADIO BROADC SUN 9 30.10 A. Guest Col. Alfred D. Reutershan. WINS. 1010 ON THE DIAL group would concern itself with BAPTIST Sunday 11 A M on ST. MARY THE VIRGIN 139 West Magr. George C. Murdock, for- registration of the qualifications of The Anthropomorphic God" 46th St. mer chaplain of the United States FIRST BAPTIST CHURCH Central Presbyterian Low Masses: 7 and 9 High Mass with Sermon (Fr. Taber). 11 the refugees. in conjunction with Missa secunda-Hassler Military Academy, will represent Street a survey by the Nationalist Chi- PASTOR 11 WHITING First Church of Religious Science Park Avenue at 64th Street REV THEODORE CUYLER SPEERS D = Evening Prayer. Address. Benediction. 8 Cardinal Spellman at the requirem nese Government on Formosa as to M Bible School Display Advertisement This 11 A M-DR SPEERS will preach Catholic Worship- Preaching mass at 12:30 P. M. in the Catholic Services A M and M MID-SUMMER S DREAM Liturgical Music which ones are needed there. by the REV DONALD MacKAY SECOND CHURCH RELIGIOUS SCIENCE Chapel at West Point. Because of overcrowding on For- FRIDAY Meeting Dr. Paul Martin Brunet ST. MICHAEL'S 99TH STREET mosa, he said, only about 5,000 Sun.. Fifth Avenue Presbyterian OFF BROADWAY REV. WILLIAM CORKER. RECTOR Caluary Baptist 123 57 53 ST. 3, H.C. 11. M. P. Sermon-Rev. J. M. Waterman WALTER S. GLADFELTER Gotham Motel refugee intellectuals could be ac- 11 A. M. Fifth Ave at 55th St. commodated there. Dr. John Summerfield Wimbush, Pastor RICHES WITHIN YOUR REACH John Sutherland Bonnell. ST. STEPHEN'S 69th Street, near Bway Special to THE NEW YORK TIMES. Thurs MP. M., How to Heal Yourself & Others Rev. Dr. Wilson Suttom M PHILADELPHIA. Aug. 15 11 A The Importance of Secret Thoughts 8. 11 A. M.-The Rev. Dr. Samuel H. Prince (M) A M The Double Crosser" Walter S. Gladfelter, assistant Pro- HILLEL DIRECTOR NAMED 10 M A ... INTERDENOMINATIONAL 30 M -How to Obtain Eternal Life 10 and Station WMGM The Rev. Hamish C. MacKenzie, M.A. Fifth Avenue fessor of Business Administration Megs THE ASSEMBLY- of Scotland, preaching at both services St. Thomas. & 53rd Street at Temple University. where he Rev. ROELIF H. BROOKS. S.T.D., Rector had been on the faculty for twen- Rabbi Frimer of Chicago Chosen Madison Avenue Baptist list St. GUILD OF CHRIST 8 and 9 A. M.-Holy Communion CHURCH OF THE CORDIAL WELCOME First Presbyterian Church 11 A. M. Morning Prayer: Rev. J. C. Francis by New York Foundations HOTEL WELLINGTON 147 w 55TH ST. Daily 8:30 A.M., Holy Communion ty-two years, died Wednesday REV DR J EARLE EDWARDS. Guest Preacher Sunday 11 M -Spiritual Maturity SERVICES 11 A M AND 4 P M 5TH AVE. BET 11th and 12th STREETS Thursday. 11 A.M.. Holy Communion SERVICE night in the York General Hos- CHARLES 11 WATTS. Speaker 11 A M.-REV GEORGE C CAMERON pital. He was 62 years old. Rabbi Norman Frimer of Chi- THE RIVERSIDE CHURCH Wed M New Mind and Heart of Dundee, Scotland LITTLE CHURCH AROUND THE CORNER cago has been named regional AIMEE LEVY. Speaker P. M -LAWN SERVICE Transfiguration One East Mr. Gladfelter, whose home was MR. CAMERON director of the B'nai B'rith Hillel at 122nd Street 29th Street in this city, was graduated from JEWISH Temple in 1927 and received a Foundations in the New York area DR. ROBERT J. McCRACKEN, Minister Madison Avenue Church Rev. RANDOLPH RAY. D. D., Rector Holy Communion 8 and 9 (daily) 8 and director of Brooklyn College 11. Choral Eucharist and Sermon-Fr. Griesmyer master's degree from the Univer- 11 A. M.-DR. JOSEPH R. SIZOO New Brunswick Theological Seminary, Cong. Rodeph Sholom Madison Ave. at 73rd Street Hillel Foundation. The founda- Rev. Frank Grebe. Preaching of Pennsylvania. and cultural New Brunswick ANOUGH St., Fri 5 30 Sat. A.M. 11 A M The Diligence of Your Hands 83rd 8 M Through Jesus Christ Our Line" PART NEWMAN - 9 1 The Marish of Margaret A. Hamburg, M.D., and Anthony S. Fauci, M.D. AIDS: The Challenge to Biomedical Research T HE SUDDEN, UNEXPECTED EMERGENCE of the acquired immunodeficiency syndrome (AIDS) has become the focus of extraordinary attention and concern. First recognized as an entity less than eight years ago, this infectious, debilitating, and ultimately lethal disease represents the most severe stage of a spec- trum of infection with the human immunodeficiency virus (HIV). It has appeared, in epidemic proportions, in an era when advances in medicine and public health have fostered great confidence in the ability of biomedical science to conquer disease. The prematurely complacent belief that infectious diseases would no longer threaten the developed world has been abruptly and definitively shattered by the onset of AIDS. As of December 1988, the United States has had more than 81,000 documented cases of AIDS and close to 46,000 deaths from the disease.¹ In the United States, 1 million to 1.5 million individuals are thought to be infected with HIV but have not yet developed clinical symptoms.² In the entire world, current estimates indicate that there are presently more than 250,000 cases of AIDS and somewhere between 5 million and 10 million individuals infected with HIV.³ It Margaret Hamburg is Special Assistant to the Director of the National Institute of Allergy and Infections Diseases at the National Institutes of Health in Bethesda, Maryland. Anthony Fauci is Director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health in Bethesda. 19 Daedalus Apring 1989 Vol 118, No. 2 20 Margaret A. Hamburg, M.D., and Anthony S. Fauci, M.D. is even more sobering to examine projections for the future. Account- ing for both the rates of progression from infection to disease and the rates of new infection, the United States Public Health Service estimates that by the end of 1992, this country will have had a total of approximately 365,000 cases of AIDS and close to 263.000 AIDS deaths. In 1992 alone, it is projected that there will be 80,000 new cases of AIDS diagnosed in this country-nearly as many cases in one year as have occurred in our entire experience with the disease to date.⁴ As the number of reported cases of AIDS mounts, the magnitude and severity of the problem becomes increasingly evident, and the urgency of developing effective strategies to prevent and control HIV infection more pronounced. From a scientific perspective, progress in understanding this disease process has moved forward at an impres- sive rate. Since the initial descriptions of the syndrome in the early 1980s, the fundamental manifestations of the disease have been documented and the general contours of the epidemic delineated. Basic research efforts have led to the discovery of the causative agent (HIV), the development of a blood test for the virus, as well as insight into the targets for the virus in the body, the body's responses to infection with the virus, and the pathogenic mechanisms whereby the virus produces its deadly effects. In recent years, a nationwide clinical trials program has been established to test experimental AIDS therapies, and several trials of AIDS vaccine candidates are currently under way. Yet despite these advances, no definitive cure or effective vaccine is yet available, and the toll of the epidemic continues to rise. The more knowledge is accumulated about the virus and the disease it produces, the more complex the picture becomes. In this article we shall attempt to outline the important accomplishments and the current status of basic and clinical AIDS research efforts and to identify certain of the promising new avenues for scientific pursuit, as well as obstacles to progress and some of the special problems that have arisen. THE INITIAL CHALLENGE: THE SEARCH FOR A CAUSE In the late 1970s, a rare type of cancer and a variety of serious infections were recognized to occur in increasing numbers of previ- ously healthy young men who resided predominantly in New York AIDS: The Challenge to Biomedical Research 21 and California. Most of this initial group of patients had Kaposi's sarcoma, an unusual skin tumor generally not seen in this age group, or Pneumocystis carinii pneumonia, a rare lung infection that virtu- ally never occurs in individuals with normal immune function. 5 First formally described in 1981 as a disease affecting homosexual and bisexual men, AIDS was later reported in intravenous drug users, hemophiliacs, and recipients of blood transfusions. It was also noted that the sexual partners of AIDS patients could contract the disease. 6 Despite the lack of an established cause for AIDS at this time, efforts to respond to the challenge of this new disease process were vigorous and drew upon many disciplines. Review of the medical literature, autopsy records, and tumor registries revealed no prece- dent for the striking new incidence of such cases. Epidemiologic studies in the United States and abroad were initially undertaken to define the affected populations and to search for clues to the cause of the disease. Such research activities, along with natural-history stud- ies of the disease, provided important insights into modes of trans- mission, patterns of disease occurrence and progression, as well as possible cofactors. Immunologic evaluation of AIDS patients revealed severe defects in their immune systems, making them susceptible to unusual cancers and so-called opportunistic infections, which a normal immune system would protect against. The damage to the immune system was observed to result predominantly from the selective depletion of a certain subset of white blood cells referred to as T4 lymphocytes. These T4 lymphocytes play a critical role in orchestrating the entire immune system and are essential to the body's defense mechanisms. It was presumed that the immune defect in these patients was acquired, but the mode of acquisition was undetermined. In 1983, a previously undescribed T-lymphotropic virus was concurrently isolated from AIDS patients by Dr. Robert Gallo at the National Institutes of Health and by Dr. Luc Montagnier at the Pasteur Institute in Paris. Early on, the virus was multiply designated as human lymphotropic virus (HTLV) III, lymphadenopathy- associated virus (LAV), and AIDS-associated retrovirus (ARV). Now officially called the human immunodeficiency virus (HIV), considerable evidence demonstrates that this organism, an RNA retrovirus belonging to the lentivirus family, is the causative agent of AIDS. Little is known with certainty about the biologic and geo- 22 Margaret A. Hamburg, M.D., and Anthony S. Fauci, M.D. graphic origins of this virus, but this would appear to be the first time in recorded history that it has spread widely in the human popula- tion. Related viruses have been observed in animal populations but do not produce disease in humans. A distinct but related virus (HIV-2) does cause disease in humans, and it is now being actively studied.⁹ RESEARCH ON HIV INFECTION AND AIDS The initial recognition of AIDS as a distinct entity created the need for intensive scientific study directed at this new disease. Truly rapid advances have been achieved, due in large part to the extraordinary foundation in basic science research developed over the past few decades. The remarkable expansion of knowledge in the areas of immunology, virology, microbiology, molecular biology, and drug and vaccine development have enabled AIDS scientists to proceed in a rational and expeditious manner. Broadly viewed, biomedical research on HIV infection and AIDS can be divided into five major scientific categories: (1) the study of the distribution of HIV infection and AIDS in the population (epidemi- ology) and the pattern of disease progression (natural history); (2) the identification and characterization of the virus that causes AIDS (the etiologic agent); (3) delineation of the mechanisms by which the virus destroys the immune system and produces disease (pathogenesis); (4) the development and testing of potential therapies for HIV infection and its complications; and (5) the development and evalu- ation of potential AIDS vaccines. Modes of Transmission and the Epidemiology of Infection The routes of HIV infection have been studied extensively. Research- ers have isolated HIV from a number of body fluids, including blood, semen, saliva, tears, urine, cerebrospinal fluid, breast milk, and cervical and vaginal secretions. However, epidemiologic evidence strongly indicates that HIV is transmitted through only three primary routes: sexual contact (including anal and vaginal intercourse) with an infected person, exposure to infected blood or blood products, and passage from an infected mother to her infant before or during birth. 10 AIDS: The Challenge to Biomedical Research 23 Current U.S. statistics reveal that the majority of sexual transmis- sions of HIV have occurred between homosexual or bisexual men, representing approximately 62 percent of all AIDS cases. Exposure to HIV-infected blood through the sharing of needles or other drug- related paraphernalia is another source of HIV infection, and intra- venous drug abusers comprise approximately 20 percent of the present cases of AIDS. An additional 7 percent of HIV cases occur among individuals who are both homosexual and intravenous drug abusers. Heterosexual HIV transmission in the United States ac- counts for roughly 4 percent of all reported AIDS cases. About 3 percent of the AIDS cases occurred through transfusion of infected blood or blood products, although the current practice of screening blood donors and testing all donated blood and plasma for HIV antibodies has virtually eliminated this route of transmission. 11 HIV transmission in breast milk is an extremely uncommon mode of spread, although it has been sporadically reported. 12 There is no scientific evidence to support the idea that the virus is transmitted through ordinary nonsexual contact. 13 Claims that HIV can be transmitted by insect transmission have been repudiated by both laboratory and epidemiologic studies. 14 Careful, ongoing epidemiologic surveillance studies are essential to monitoring levels of HIV infection and trends in new infection among groups recognized to be at increased risk (such as homosexual males and intravenous drug abusers), various demographic subgroups (based on sex, age, and race or ethnic group), and the general population. Considerably more needs to be learned about the con- tributing factors and quantitative risks of HIV infection through various transmission modes, including type of sexual contact, mother-to-infant transmission, patterns of intravenous drug abuse, receipt of blood or blood products, and occupational exposures to blood or infected fluids. Such data are of critical importance to assessing the mechanisms of transmissibility of the virus, its biologic determinants, and/or the cofactors influencing individual susceptibil- ity to infection. Both the biomedical and the public-health implica- tions of such information are enormous. Following infection with HIV, a person may experience an acute, transient, mononucleosis-like febrile illness but generally remains virtually asymptomatic for several years before progressive immuno- logic deterioration results in the opportunistic infections or cancers 24 Margaret A. Hamburg, M.D., and Anthony S. Fauci, M.D. that characterize the diagnosis of AIDS. 15 The period between initial infection with HIV and the development of AIDS can be quite variable. Recent data indicate that 15 percent to 46 percent of HIV-infected individuals will develop AIDS within seven years of infection. 16 Over the longer term, statistics on HIV disease progres- sion remain to be determined, but many scientists fear that in the absence of the discovery of effective therapeutic interventions, virtu- ally 100 percent of those infected with the virus will eventually develop acute AIDS. Furthermore, although asymptomatic HIV- infected individuals may appear healthy, a growing body of evidence suggests that they progressively experience subtle but important subclinical defects of immune function. There is increasing recognition that the clinical syndrome of AIDS represents the terminal stage of a spectrum of HIV infection. Once the diagnosis of AIDS is made, the clinical course generally follows a relentless decline, with death occurring within one or two years. However, earlier diagnosis, the development of the antiviral agent Zidovudine (AZT), and improvements in the treatment of the complications of HIV infection are leading to prolonged survival for persons with AIDS. 17 In addition, intensive research efforts are being focused now on the critical period between initial infection and the fully developed disease. New insights may enable early interventions to arrest or slow progression of HIV infection prior to the development of AIDS. The Nature of the Virus Following identification of the causative agent of AIDS (HIV-1), intensive efforts to investigate the nature of the virus, its functions, and its effect on human cells began. Knowledge has accumulated at a pace unprecedented for research on disease-causing micro- organisms. As seen through an electron microscope, the HIV RNA retrovirus appears as a dense cylindrical core encasing two molecules of the viral genome (genetic material). A spherical outer envelope surrounds the central core. 18 The genetic material of the virus has been cloned and sequenced and its precise structure delineated. For the most part, the specific functions of the viral genes as well as the functions of the proteins encoded by those genes have been identified and studied. 19 Such understandings serve as the basis for many important AIDS AIDS: The Challenge to Biomedical Research 25 research endeavors, including attempts on a molecular level to interfere with specific functions of the virus and to influence infectiv- ity by manipulating specific components of the virus. Scientists are also using information about the nature and function of the HIV genome to provide a framework for the development of potential AIDS vaccines and to attempt to develop antiretroviral drugs in a targeted fashion designed to interfere with the ability of the virus to replicate itself or cause infection. In addition, isolation of the virus has made possible the development of HIV blood-screening tests. This has important public-health applications for safeguarding the blood supply, as well as for diagnostic and surveillance purposes. Significant progress has also been made in understanding the life cycle of the virus. Similar to other viruses, HIV cannot reproduce without taking over the biosynthetic machinery of the host cell. Like all retroviruses, HIV possesses a special enzyme, reverse transcrip- tase, which is capable of making a DNA copy of the viral RNA. This enables the virus to reverse the normal flow of genetic information from RNA to DNA (referred to as proviral DNA), which is then incorporated or integrated into the genetic material of the host. Once integrated, the virus can remain in a latent state for a variable, often lengthy, period until activated.²⁰ That HIV is a retrovirus, with this unique ability to insert its genes into the genetic machinery of the host cell, greatly complicates the task of developing effective therapies and vaccines. HIV can remain dormant or latent, shielded from either pharmacologic or immuno- logic attack. While developing therapies for viral diseases has always been problematic, devising an antiretroviral therapy may prove even more difficult. Nonetheless, the HIV replicative cycle offers several opportunities for effective intervention. One area of investigation concerns the critical step in HIV infection whereby the virus binds to a host cell receptor to gain entrance to the cell. It has been demonstrated that a molecule called CD4-expressed predominantly on the surface of T4 lymphocytes-serves as a receptor for HIV. 21 Thus, the T4 cell represents a major target for HIV infection: however, other cells expressing the CD4 surface molecule are capable of binding and becoming infected with HIV. Various mechanisms have been pro- posed to interfere with this process of virus-receptor binding and entrance into host cells. Several are under active study. 22 Another 26 Margaret A. Hamburg, M.D., and Anthony S. Fauci, M.D. area of investigation involves interfering with the activity of the enzyme reverse transcriptase, thereby disrupting a crucial initial step in the replicative cycle of the virus. Other potential targets of vulnerability of the virus include interference with proviral DNA transcription (the process by which genetic information contained in DNA is translated into an RNA message), disruption of the subse- quent protein synthesis, processing, and assembly and the final stage of viral replication in which mature virions bud off from host cells. 23 The Attack on the Immune System HIV infection can result in a wide range of immunologic and clinical abnormalities. Although multiple components of the immune system are at least indirectly affected in individuals with HIV infection, it is the impairment of the responses mediated by the class of lymphocytes called T4 cells that appears to produce the most significant clinical consequences. 24 Because the T4 cell is pivotally involved in virtually all immune responses, a major host defense defect results from T4-cell depletion and renders the body highly susceptible to oppor- tunistic infections and neoplasms. It has recently been demonstrated that certain other types of white blood cells called monocytes and macrophages, including bone marrow precursor cells, can be infected without marked cell damage. 25 The monocyte, which moves rela- tively freely throughout the body, may serve as a reservoir for HIV and may play a significant role in the propagation of HIV infection and the development of AIDS. It is now well established that the brain is also a target for HIV. 26 Present evidence suggests that many of the central nervous system manifestations of HIV are produced by infected monocytes that travel into the brain and indirectly damage neuronal tissue. Research reveals no evidence to support direct infection of nerve cells by HIV. The development of a new technique called polymerase chain reaction (PCR) will greatly enhance the ability of scientists to detect the presence of HIV genetic material in cells. This technique involves selective DNA amplification and makes it possible to multiply otherwise undetectable fragments of DNA. Using PCR, it is possible to determine the presence of HIV viral genes in blood samples in which as few as 1 in 1 million lymphocytes is infected. 27 The AIDS: The Challenge to Biomedical Research 27 expanding use of PCR in AIDS research will result in important new insights into the nature and extent of HIV infection. Considerable progress has been made in understanding the patho- genic mechanisms of HIV infection, including the receptor whereby the virus gains entry into the cell and the subsequent intracellular events of the virus life cycle and replication. The disease complica- tions that result from the virus-induced destruction of immune cells have also been fairly extensively delineated. Nonetheless, some of the most basic mechanisms by which HIV exerts its lethal effects on host immune cells remain unknown. In test-tube experiments, HIV can be demonstrated to rapidly kill the cells it infects. It is not clear, however, that such a phenomenon can fully explain the profound depletion of T4 cells observed in patients with AIDS, since only a small percentage of the T4 cells in the peripheral blood (perhaps less than 1 in 10,000) is found to express the virus at any given time. Several proposed explanations for this apparent discrepancy are currently being explored. 28 A better understanding of the process of cell destruction by HIV will therefore be important to the develop- ment of effective interventions. Because the clinical syndrome of AIDS follows infection with HIV after a variable, often long, period, there is a pressing need to learn more about this interval between initial infection and acute disease. It may well be that our best prospects for treatment and control of HIV disease will come through interventions during this critical time. Toward this end, intensive efforts must be directed toward unraveling the mechanisms of immune-system dysfunction and the factors that influence or control disease progression. Laboratory experiments have demonstrated that when certain cells are infected with HIV, latent infection may ensue, with the viral DNA becoming integrated into the DNA of the host cell without virus production. 29 In addition, infection may be chronic in a given cell with a low level of virus production or expression. A variety of activation signals, including other viruses as well as substances produced by immune-competent cells following stimulation, appear to contribute to the conversion of a latent or a chronic infection to a productive one. 30 Modification of these activation signals-either pharmacologic or otherwise-may have important implications for 28 Margaret A. Hamburg. M.D., and Anthony S. Fauci. M.D. potential strategies to limit the progression of HIV infection and of AIDS. The Search for a Treatment Researchers are in the midst of a major effort to discover, develop, and test potential therapies for HIV infection and AIDS. These efforts have focused on two major areas: (1) antiviral drugs with a direct effect against the causative agent, HIV, and (2) immunomodulators that act to reconstitute or enhance immune-system function in patients with HIV infection and AIDS. Efforts to develop and improve-approaches to treat the specific opportunistic infections and cancers associated with AIDS are also moving forward. The successful development of antiviral and/or immune enhance- ment therapy represents a challenge of enormous magnitude. Basic scientific understandings must obviously underlie the process of rational development of therapeutic agents. Unlike any other known pathogen, HIV infects the very cells of the immune system that are intended to direct the immune system's attack against such invaders. In addition, because the virus becomes intimately associated with the host cells during the course of its life cycle, the task of finding a safe and effective therapeutic agent is even more formidable. It will be necessary to discover a means to interrupt the life cycle of the virus within the cells it invades without killing the cells themselves and destroying the already threatened immune system. Also, cell-free viruses must be eliminated, and the spread of the virus to uninfected cells prevented. Furthermore, recent studies indicate that there may be several important reservoirs for HIV in the body that will be difficult to eliminate without causing fundamental damage to the host cells involved. For example, cells of the monocyte-macrophage line, important components of the immune system, can not only be infected but can also support HIV replication while harboring the virus from the body's immune surveillance. Circulating monocytes and macrophages appear to play an important role in the dissemina- tion of HIV throughout the body, including the brain. 31 Recent studies suggest that bone-marrow precursor cells of monocyte lineage may be an additional reservoir of HIV. 32 In the search for effective therapy, due consideration must be given to ensuring that the agent(s) can penetrate into the involved sites. For example, as the brain is an important target for HIV infection, any effective anti-HIV agent. AIDS: The Challenge to Biomedical Research 29 should be able to cross the blood-brain barrier. Other practical considerations in AIDS drug development must include cost, dosing schedule, and the route of administration. Preclinical Drug Development-Researchers attempting to dis- cover and develop anti-HIV. drugs are pursuing two approaches: screening large numbers of existing compounds for activity against HIV and targeting drug development with information gained about unique properties and critical functions of the virus to design agents that interfere with structural components or the life cycle of the virus. To date, literally thousands of compounds have been studied in the test tube for activity against HIV. Of these, several have been identified to show significant anti-HIV activity and have advanced to clinical trials in humans. 33 Nonetheless, there is fairly broad scientific consensus that definitive therapies for HIV infection will derive from precise, targeted drug development based on intimate knowledge of the virus, its life cycle, and the delineation of specific sites and mechanisms for disrupting viral replication or viability. This may be a painstaking and difficult process, requiring the talents of virologists, molecular biologists, pharmacologists, physical chemists, and crys- tallographers, among others, and may take years to show results. Clinical Trials of Experimental Drugs-Clinical trials are designed to investigate the beneficial and adverse effects of drugs that show promise in the laboratory or in preliminary clinical studies. Because of the experimental nature of such potential therapies, it is essential that they be carefully and scientifically studied for safety and efficacy before being widely distributed. Many clinical research efforts are under way, including a major, nationwide clinical trials network established by the National Institutes of Health (NIH) to study potential antiretroviral and immunomodulatory treatment ap- proaches in persons infected with HIV, as well as specific therapies (including prophylaxis) for the opportunistic infections and malig- nancies associated with HIV infection. At the present time, AZT, a compound that interferes with virus replication, is the only drug licensed by the Food and Drug Admin- istration (FDA) for the treatment of HIV infection. Its potential use as a therapeutic agent against HIV was originally demonstrated in the test tube by the screening procedure mentioned above. Carefully conducted clinical trials subsequently demonstrated that AZT admin- 30 Margaret A. Hamburg, M.D., and Anthony S. Fauci. M.D. istration could significantly prolong life for certain individuals with AIDS, although its use can be associated with considerable toxic side effects, including bone-marrow suppression. 34 A number of related antiviral compounds are being investigated now to see if they might be equally effective with fewer side effects. Other drugs, both alone and in combination with lower doses of AZT, are also being tried in the hope of achieving greater benefit with reduced toxicities. In many ways, combination therapy represents the most promising new approach to the treatment of HIV infection. For example, the agent 3'-dideoxycytidine (ddC) has good antiviral activity without AZT's marrow-suppressive effects, but it has the dose-limiting tox- icity of producing what is called a peripheral neuropathy with severe. damaging pain in the feet. By alternating AZT-treatment with ddC. patients may be able to receive therapy for longer periods of time, at higher doses, and with fewer side effects. Similarly, bone-marrow suppression might be lessened through the combination of drugs like AZT with compounds that can boost blood-cell counts, such as erythropoeitin or granulocyte-macrophage-colony-stimulating, factor (GM-CSF). Another intriguing approach involves combining antivi- ral therapy with immunologic reconstitution, either with biological response modifiers that can boost immune response such as alpha- interferon and interleukin-2 or through bone-marrow transplanta- tion techniques. 35 This approach provides a potential two-pronged attack aimed at suppressing viral replication at the same time that the damaged immune system is restored. Several drugs have shown evidence of therapeutic value against the major opportunistic illnesses seen in AIDS. Important examples include the use of aerosolized pentamidine to prevent Pneumocystis carinii pneumonia (the leading cause of death among AIDS patients), as well as the use of the antiviral drugs foscarnet and ganciclovir (DHPG) in controlling the progression of cytomegalovirus retinitis. Studies of these and other potential therapies are currently under way to evaluate definitively their safety and efficacy. Altogether, dozens of agents for use in HIVinfection and AIDS are currently being tested in clinical trials in this country and around the world. There is a growing emphasis on exploring means for early thera- peutic intervention in HIV infection in order to limit or prevent progression to full-blown AIDS. A number of important studies are near implementation or are already under way to examine the AIDS: The Challenge to Biomedical Research 31 influence of experimental therapies in early stages of the disease, in infected but asymptomatic individuals, and even in pregnant women who are HIV-infected (so as to prevent infection in the fetus). Considerable attention is also being directed at finding treatments that will prevent the onset of certain opportunistic complications of HIV disease. The advances currently being made in drug discovery, develop- ment, and therapeutic intervention provide a basis for cautious optimism that a number of useful agents may be available relatively soon. Realistically, there may never be an absolute cure for AIDS. At least for the next few years, it is likely that the best hopes for treatment will come from drugs or combinations of drugs that will permit sufficient control of the infection so that HIV-infected indi- viduals can live healthier lives with a reasonable life span and no longer infect others. Need for Continued Commitment to Scientific Basis for Clinical Trials-Given the life-threatening nature of HIV infection and AIDS, there is a growing tension between the understandable desire to make potential therapies available as quickly and as widely as possible, and the need to obtain correct and enduring answers through carefully designed scientific research. Concern has been expressed that scientists are rigidly adhering to experimental traditions that are not relevant to the AIDS crisis and that impede progress to solutions. In view of the lethal threat posed by the underlying disease, the very rationale for conducting method- ical, controlled clinical trials of experimental AIDS therapies has been called into question; many believe that experimental clinical drug protocols are too complex, take too long to develop, and once developed are too restrictive in their criteria for admission and execution. Correspondingly, there is strong pressure on the scientific community to loosen the standard practices used for evaluating drugs and to abandon the need to scientifically prove both safety and efficacy. Yet, for reasons of both safety and science, carefully con- trolled clinical trials are necessary. Clinical trials may put conditions or restrictions on participation that may be perceived as unnecessary but that are critical to obtaining clear, unambiguous results. For example, it is essential that the population participating in the clinical trial be carefully defined and 32 Margaret A. Hamburg, M.D., and Anthony S. Fauci, M.D. relatively homogeneous in certain manifestations and stages of the disease because a given drug may be effective only at a certain stage in the disease process or for a particular subpopulation of patients. Furthermore, there may be circumstances in which the endpoints of drug efficacy are not as dramatic as life and death but may, rather, involve subtle changes in parameters that require careful monitoring. Potentially important results may not be recognized without careful attention to study design and conduct. Because of the risks inherent in any experiment involving human subjects-and a clinical trial is indeed an experiment-there is a valid and generally agreed-on principle to expose the minimal number of individuals to the risks of the experiment. Nonetheless, many persons with AIDS, desperate for access to any potentially useful drug, argue that they are more than willing to assume such risks. While greater availability of experimental drugs does offer some initial hope and the immediate gratification of taking some action against this relentless disease, it would be incorrect to equate the showing of compassion with the widespread distribution of untested agents to HIV-infected individuals. Open distribution of unproven therapies is unlikely to help their recipients in the short term and will certainly undermine long-term prospects to conclusively determine effective therapies. From a purely analytic perspective, there is little disagreement that well-designed clinical trials provide the most efficient mechanism to determine definitively what treatments work. Such clinical trials will ultimately benefit more patients, and sooner, than any other ap- proach. Past experience warns that compromising the precepts of scientific evaluation may lead to deleterious results. Truly effective drugs may be overlooked or discarded, either because of failure to appreciate subtle beneficial effects that might be missed in a poorly designed and implemented trial or because of exaggerated concern about the relative risks of side effects. Conversely, harmful or useless drugs may be accepted for use; such drugs may even be prescribed in lieu of other treatments of more proven benefit. It is only through carefully designed clinical research efforts that definitive answers will be found for this devastating disease-both for those presently suffering from AIDS as well as for the hundreds of thousands of persons who are infected with HIV but not yet sick. AIDS: The Challenge to Biomedical Research 33 Without compromising sound scientific principles, there is an ongoing effort to expedite clinical trials. For example, the possibility of shortening the trial process and providing earlier access to exper- imental drugs that have shown promise of efficacy without serious toxic side effects is under consideration by the FDA. The challenge for policymakers will be to achieve the difficult balance between the rigorous demands of the scientific method necessary to improve therapy and the rights of patients suffering from life-threatening diseases to gain access to new therapies at the earliest possible time. Improved Access to Clinical Trials-In a distinct but related matter, there is a pressing need to provide a broader spectrum of the infected population with greater access to clinical trials of investiga- tional drugs. Clinical research activities are usually conducted at academic medical centers, whereas most patients with HIV infection are cared for in a community setting by nonacademically affiliated providers. Not surprisingly, this situation has been reflected in an underrepresentation of minorities, women, children, hemophiliacs, and those with problems of IV drug use in clinical trials. Future AIDS clinical research efforts must expand the population profile enrolled in clinical trials and foster a greater involvement on the part of community-based primary health-care providers. Worthwhile opportunities exist to broaden the base of clinical research efforts by increasing the participation of community physi- cians and patients in both the design and the implementation of AIDS-related research projects. At this time, concerted efforts are being directed toward developing research activities that are innova- tive and responsive to community needs as well as consistent with sound criteria for scientific research. Valuable treatment research could be conducted at the community level, including clinical trials of new therapies, but might also involve surveillance of ongoing clinical experience with some of the many therapies being used on an ad hoc, "on the streets" basis. In addition, systematic collection of data from actual practice settings-if done prospectively and in a careful, rigorous fashion-could provide very 34 Margaret A. Hamburg, M.D., and Anthony S. Fauci, M.D. useful, albeit exploratory, information about the value of popular but unstudied treatments. The Search for a Vaccine The development of a vaccine against HIV infection has assumed a prominent position in the strategies for prevention and control of AIDS. However, despite intensive research in this area and consider- able scientific advance, there is little hope of having a safe and effective vaccine available in the near future. Developing a successful vaccine against HIV infection will be difficult for several reasons. The first is due to properties of the virus itself. Many different strains of HIV exist, and even within one person's body the virus can undergo mutations rapidly and easily. 36 In addition, scientists still do not fully understand the nature of an effective immune response that can protect against initial infection or disease progression following infection. The process of vaccine development for other diseases, such as polio and influenza, has been facilitated by the ability to study the nature of the immune response in individuals who have recovered without treatment and then to use their natural immune response as a model for vaccines. AIDS researchers have had no such opportunity, since no one has yet recovered from the disease. The task of researchers in this area is further complicated by the lack of adequate animal models for AIDS. Despite these handicaps, scientists using knowledge about the structure of the HIV and sound immunologic principles have been attempting to develop a vaccine. The aim is to induce neutralizing antibodies as well as cell-mediated responses against HIV and thereby to protect uninfected individuals against subsequent infection if they are exposed to the virus. Vaccine development and testing must be carefully designed to ensure that the vaccines will be safe and will elicit an immune response. The approaches to vaccine development that are being explored include the use of whole killed virus, purified natural products of the virus, synthetic preparations of virus components, recombinant DNA products, recombinant vaccinia virus containing parts of the HIV genome, and what is termed anti-idiotype, meaning antibodies generated against antibodies to the virus. 37 To eliminate the possibility that the vaccine itself might be infectious, most AIDS vaccine researchers are using some form of subunit vaccine product AIDS: The Challenge to Biomedical Research 35 (consisting of protein components of the virus rather than the whole virus) in their attempts to stimulate immune responses. The whole killed virus approach raises some concern because of the ability of HIV to integrate into the cell's genetic machinery. Theoretically, a whole killed virus vaccine could introduce viral genetic material into host cells and trigger tumor development or other undesirable side effects. However, given the multiple and variable strains of HIV found, the whole killed virus approach may prove preferable because of its ability to elicit a protective immune response that is effective against many strains of HIV. This hypothesis is based on the observation that the individuals naturally infected with live HIV develop antibodies that are broadly reactive with a range of HIV isolates or strains. In contrast, the immune response to the subunit vaccine appears at this point to be limited to the original strain of virus used to make the vaccine.³⁸ To date, some studies using subunit vaccines-in particular those based on segments of the viral envelope-have been shown to stimulate antibody synthesis in rodent and primate models. Certain of the antibodies produced have been shown to be so-called neutral- izing antibodies, capable of blocking HIV infection in tissue culture systems. However, the neutralizing antibody responses were unable to protect against subsequent HIV infection in the animals. 39 These findings are in keeping with clinical observations in which no correlation is found between levels of neutralizing antibody and the progression of infection in patients. 40 In general, candidate vaccines are clinically evaluated in humans only after safety and immunogenicity are demonstrated in laboratory and animal studies. However, given the urgency of the AIDS epi- demic, the FDA has approved human trials of a limited number of potential AIDS vaccines, despite the lack of animal data or a clear delineation of the requirements for a protective immune response in humans. Several candidate vaccines are now in the early phases of testing in human volunteers, in both the United States and elsewhere. 41 A significant dilemma in the evaluation of an AIDS vaccine is how to test candidate vaccines for efficacy. Because AIDS is a fatal disease, it would be ethically unthinkable to deliberately expose a study volunteer to HIV. Therefore, the only available way to show efficacy is to administer the vaccine to a large number of individuals identified 36 Margaret A. Hamburg, M.D., and Anthony S. Fauci. M.D. as being at risk for developing HIV infection and then follow them over a long period of time. If the incidence of new infection in a population at risk is low-as is currently the case for male homosex- uals in the United States-literally thousands of people would have to be enrolled in a vaccine trial to achieve meaningful results. Further- more, ethical considerations would dictate that participants in the vaccine trial receive appropriate instruction about how to avoid HIV infection, making the demonstration of the efficacy of a vaccine still more difficult. It has been suggested that a candidate vaccine would be most effectively evaluated for efficacy if tested in areas of the world where incidence and prevalence rates for HIV infection are highest. Studies conducted in such localés-including certain developing nations particularly hard hit by the HIV epidemic, such as those of central Africa-would yield more rapid and discernable results, and the potential benefits would be considerable.⁴ Nonetheless, vaccine testing in such settings has numerous complications. These include problems of different strains of the virus, difficulties in long-term followup, lack of infrastructure for appropriate clinical evaluation, and multiple social, cultural, and political considerations. * * *- The magnitude of the AIDS epidemic and the urgency of develop- ing treatments or a cure represent an enormous challenge for biomedical research. Building upon a strong foundation of knowl- edge accumulated over several decades of research in such fields as immunology, microbiology, infectious diseases, molecular biology, and epidemiology, AIDS research efforts have moved forward swiftly and productively since this new disease was first recognized. Seldom has biomedical science progressed so rapidly, yet real solutions to the control and prevention of HIV infection remain elusive. Perhaps more than any other disease, AIDS has raised a host of complex questions, from the most fundamental nature of biological systems to the role of scientific research in society at large. And beyond the challenge to biomedical research, there are profound and broader implications of the AIDS crisis for many aspects of health care, law, ethics, and society. The needs are tremendous and the answers difficult, but we are moving forward and new solutions are within AIDS: The Challenge to Biomedical Research 37 our grasp. The benefits will be far-reaching-not just for AIDS, but for many other areas of health and disease as well. ENDNOTES 'Centers for Disease Control, Acquired Immunodeficiency Syndrome Weekly Surveillance Report, (Atlanta, Ga.: Centers for Disease Control, 26 December 1988). ²Public Health Service, Department of Health and Human Services, Quarterly Report to the Domestic Policy Council on the Prevalence and Rate of Spread of HIV in the United States (Atlanta, Ga.: Centers for Disease Control, July 1988). ³P. Piot, F. A. Plummer, F.S. Mhalu, et al., "AIDS: An International Perspective," Science 239 (4840) (1988):573-79. ⁴Public Health Service. ⁵M. S. Gottlieb, R. Schroff, H. M. Schanker, et al., "Pneumocystis Carinii Pneumonia and Mucosal Candidiasis in Previously Healthy Homosexual Men: Evidence of a New Acquired Cellular Immunodeficiency," New England Journal of Medicine 305 (1981): 1425-31; and H. Masur, M. A. Michelis. J. B. Greene, et al., "An Outbreak of Community-Acquired Pneumocystis Carinii Pneumonia: Initial Manifestation of Cellular Immune Dysfunction," New England Journal of Medicine 305 (1981): 1431-38. "Masur et al.; and Centers for Disease Control, "Kaposi's Sarcoma and Pneumo- cvstis Pneumonia among Homosexual Men-New York City and California." Morbidity and Mortality Weekly Report 30 (3 July 1981):305-8. Public Health Service: and Centers for Disease Control, "Update on Acquired Immune Deficiency Syndrome (AIDS) United States," Morbidity and Mortality Weekly Report 31 (24 September 1982):507-14. R. C. Gallo, S.Z. Salahuddin, M. Popovic, et al., "Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk tor AIDS," Science 224 (1984):500-502; F. Barre-Sinoussi, J. C. Chermann, F. Rev, et al., "Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)," Science 220 (1984):868-71: and J. A. Levy, A. D. Hoffman, S. M. Kramer. et al., "Isolation of Lymphocyto- pathic Retroviruses from San Francisco Patients with AIDS," Science 225 (1984): 840-42. R. C. Gallo and L. Montagnier, "AIDS in 1988," Scientific American 259 (1988): 40-48. ¹⁰J. W. Curran, H. W. Jaffe. A. M. Hardy, et al., "Epidemiology of HIV Infection and AIDS in the United States," Science 239 (4840) (1988):610-16. 11 Centers for Disease Control, Acquired Immunodeficiency Syndrome. ¹²S. Logan, M. Newell. T. Ades, et al., "Breast Feeding and HIV Infection," Lancet (11 June 1988):1346. 38 Margaret A. Hamburg, M.D., and Anthony S. Fauci, M.D. ¹³M. A. Sande, "Transmission of AIDS: The Case against Casual Contagion," New England Journal of Medicine 314 (6) (1986):380-82. 14U. S. Congress, Office of Technology Assessment, "Do Insects Transmit AIDS?" a staff paper in OTA's series on AIDS-related issues (Washington, D.C.: Govern- ment Printing Office, 1987). ¹⁵R. R. Redfield and D. S. Burke, "HIV Infection:- The Clinical Picture," Scientific American 259 (October 1988):90-98. ¹⁶Curran et al. ¹⁷Redfield and Burke. ¹⁸A. B. Rabson and M. A. Martin, "Molecular Organization of the AIDS Retrovi- rus," Cell 40 (1985):477-80. 19W. A. Haseltine and F. Wong-Staal, "The Molecular Biology of the AIDS Virus," Scientific American 259 (October 1988):52-62. 20Ibid. ²¹S. Koenig and A.S. Fauci, "AIDS: Immunopathogenesis and Immune Response to Human Immunodeficiency Virus," in V. T. DeVita, Jr., S. Hellman and S. A. Rosenberg, eds., AIDS: Etiology. Diagnosis, Treatment, and Prevention, 2nd ed. (Philadelphia, J. B. Lippincort Company, 1988). 61-77. 22S. Broder and A. S. Fauci, "Progress in Drug Therapies for HIV Infection," Public Health Reports 103 (May-June 1988):224-28. 231bid. ²⁴Koenig and Fauci. ²⁵Ibid.; and T. M. Folks, S. W. Kessler, J. M. Orenstein, et al.. "Infection and Replication of Human Immunodeficiency Virus-1 (HIV-1) in Highly Purified Progenitor Cells from Normal Human Bone Marrow," Science 242 (1988): 919-22. 26R. W. Price, B. Brew, J. Sidtis, et al., "The Brain in AIDS: Central Nervous System HIV-1 Infection and AIDS Dementia Complex," Science 239 (4840) (1988):586- 92. 27S. Kwok, D. H. Mack, K. B. Mullis, et al., "Identification of Human Immunode- ficiency Virus Sequences by Using in Vitro Enzymatic Amplification and Oligo- mer Cleavage Detection," Journal of Virology 61 (1987): 1690-94. 2⁸A. S. Fauci, "The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis," Science 239 (4840) (1988):617-22. 29Gallo and Montagnier. ³⁰Kwok, Mack, Mullis, et al. 31 Fauci. ³²Price, Brew, Sidtis, et al. ³³Folks, Kessler, Orenstein, et al. AIDS: The Challenge to Biomedical Research 39 34 Broder and Fauci. 35 Ibid. ³⁶A. G. Fisher, B. Ensoli, D. Looney, et al., "Biologically Diverse Molecular Variants within a Single HIV-1 Isolate," Nature 334 (1988):444-47. ³⁷W. C. Koff and D. F. Hoth, "Development and Testing of AIDS Vaccines," Science 241 (1988):426-32. ³⁸lbid. 39 A. M. Prince, B. Horowitz, B. L. Baker, et al., "Failure of an HIV Immune Globulin to Protect Chimpanzees Against Experimental Challenge with HIV," Proceedings of the National Academy of Sciences (forthcoming). ⁴Broder and Fauci; and M. Robert-Guroff, M. Brown, and R. C. Gallo, "HTLV- III-neutralizing Antibodies in Patients with AIDS and AIDS-related Complex," Nature 316 (1985):72-74. 41 Koff and Hoth. ⁴²Institute of Medicine, Prospects for Vaccines against HIV Infection, report of the Conference on Promoting Development of Vaccines Against Human Immunode- ficiency Virus Infection and Acquired Immune Deficiency Syndrome (Wash- ington, D.C.: National Academy Press, 14-15 December 1987). Justice/State waiver of AIDS S.F. (June30th) couf. amotisabilities Oct. jo along w/ W.H.O. Document Originally Attached to Previous Page STEVE CA PRESS GUIDANCE Wednesday, January 17, 1990 VISAS: POLICY RE AIDS VICTIMS Q: Is it true that the U.S. Government is easing, but not eliminating, restrictions on the freedom of people infected with AIDS to enter the U.S.? A : -- UNDER THE IMMIGRATION & NATIONALITY ACT, VISA APPLICANTS WHO ARE HIV-POSITIVE ARE INELIGIBLE FOR VISAS BECAUSE THEY ARE AFFLICTED BY A "DANGEROUS CONTAGIOUS DISEASE." AS IN ALL SUCH CASES, WAIVERS MAY BE OBTAINED FROM THE IMMIGRATION & NATURALIZATION SERVICE. -- A SIXTH INTERNATIONAL CONFERENCE ON AIDS IS BEING PLANNED FOR JUNE 1990 IN SAN FRANCISCO. THE WORLD HEMOPHILIA CONFERENCE IS SCHEDULED FOR AUGUST 1990 IN WASHINGTON, D.C. -- THE STATE DEPARTMENT, THE IMMIGRATION & NATURALIZATION SERVICE, AND THE U.S. PUBLIC HEALTH SERVICE HAVE AGREED ON CERTAIN SPECIAL PROCEDURES SO AS TO FACILITATE TRAVEL TO THE U.S. BY HIV-POSITIVE PERSONS WISHING TO ATTEND EITHER OF THESE CONFERENCES. -2- -- THE PROCEDURES ARE AS FOLLOWS: (1) IN THOSE CASES WHERE AN HIV-INELIGIBLE APPLICANT INDICATES AN INTENTION TO REMAIN IN THE U.S. FOR THIRTY DAYS OR LESS TO PARTICIPATE IN THE SIXTH INTERNATIONAL CONFERENCE ON AIDS OR THE WORLD HEMOPHILIA CONGRESS, AND REQUESTS A WAIVER OF INELIGIBILITY, THE CONSULAR OFFICER SHALL ASSUME IMMIGRATION & NATURALIZATION SERVICE APPROVAL OF A WAIVER REQUEST AND ISSUE THE VISA. (2) IF THE HIV-POSITIVE APPLICANT OBJECTS TO HAVING THE WAIVER ANNOTATION PLACED IN HIS OR HER PASSPORT, THE CONSULAR OFFICER SHALL STAMP THE VISA AND PLACE THE NOTATION ON A SPECIAL FORM. (3) ALL APPLICATIONS, WAIVER REQUESTS, OR OTHER RECORDS OR COMMUNICATIONS ON HIV-POSITIVE PERSONS TRAVELING TO THE U.S. TO ATTEND THESE TWO CONFERENCES WILL BE TREATED AS CONFIDENTIAL (LIMITED OFFICIAL USE) ONLY AMERICANS AND FOREIGN SERVICE NATIONAL EMPLOYEES WITH APPROPRIATE CLEARANCES WILL BE ALLOWED ACCESS TO SUCH INFORMATION. -3- - Q: Do you expect these procedures to satisfy those groups now threatening to boycott the conferences because of U.S. policy? A: WE DO NOT EXPECT THESE CHANGES TO SATISFY EVERYONE WHO OBJECTS TO U.S. LAW ON THE ADMISSION OF HIV-POSITIVE APPLICANTS. HOWEVER, WE BELIEVE THAT THIS IS AS MUCH AS WE CAN DO WITHIN THE LIMITS OF THE LAW AS IT NOW STANDS. Q: Will this apply to future AIDS conferences? A: WE WILL CONSIDER FUTURE CONTINGENCIES AS THEY ARISE. Drafted: CA/PA:FTJones 01/17/89 ext. 71488 Doc#:0103y Clearance: Info: CA/PA:PCovington H:PDoherty CA/VO/F/P:CHoward ARA/P:ASigmund EUR/P: NWhite AF/P:GMorris EAP/P:MCYates NEA/P:DGoode ROUTINE RUSH MESSAGE NO Peggy Polk TO DATE 3/7/90 Lee C. Smith, Levi Strauss International FROM 2 NUMBER OF PAGES SUBJECT ADDITIONAL DOCUMENTS ATTACHED IF THERE IS A TRANSMISSION PROBLEM, CALL 415/544-6091 TEXT: LEVI STRAUSS & CO. P.O. Box 7215, San Francisco, CA 94120 Phone: 415/544-6000 FAX: 415/544-3939 Following are the suggested themes for the March 29th "Presidential Address". OBJECTIVE To provide national leadership and legitimize the HIV disease thereby providing hope to those directly and indirectly affected by AIDS. Setting the fiscal pressures aside, there is a vital need for leadership, vision, education and collaboration from the executive branch. TONE Positive, direct, encouraging and supportive. ISSUES 1. The AIDS epidemic is NOT over. We have made huge gains and enormous advances. But hundreds of thousands of Americans are infected and will become ill, and thousands are at risk for new infection. We must be vigilant in our commitment to AIDS prevention as we move forward to address the ever changing health care needs of those with HIV disease. We must support the healthy, positive behavior change that has occurred in communities at great risk for HIV disease. 2. The federal government intends to take a leadership role in wiping out discrimination against people who are HIV positive - including immigration restrictions. Those with the disease must not be abandoned, must not be written off. They are part of the American fabric and are deserving of our support, our compassion and our respect. 3. At a time when federal budget resources are tight, I want to work cooperatively with Congress to ensure that the 1991 budget includes adequate funds for research, prevention, public eduation and patient care. POI 3363 111 SIS IS IA37* WV 11:39 06 '20 '80 4. AIDS is everyone's responsibility. Every American, every public official and every business organization needs to enlist in the fight against the HIV virus. Business leadership is vital at the local level. We need our business leaders to lend their expertise, volunteers and resources to our local community-based AIDS service organizations that have shouldered the burden in the struggle to date. 5. The business community can improve health benefits and access to decent, affordable health care for its employees. AIDS is exacerbating an already over burdened and costly health care system. The business community should lead the way in addressing systematic changes necessary to lower health care costs, provide access to treatment for those in need and prevent or delay disease progression. The private sector must carry its fair share of the health care burden without instituting or condoning unfair discriminatory practices in private insurance coverage. This is critical to implementing sane early intervention programs making life extending drugs available, through insurance coverage, to all who require them. SUMMARY My goal is to eliminate further HIV infection and I want to be sure that those already infected receive appropriate care and compassion. The only way to accomplish this is through an effective, efficient public/private partnership where we can step up public education programs, support early intervention and provide a continuum of care for our fellow citizens that have the HIV disease. PO2 3353 111 115 IS IA37* WA 11139 06 .20 OF Nov. 30 / Administration of George Bush, 1989 of millions of dollars of illegal income in the at present, we will continue the most vigor- Statement by Press form of bribes and kickbacks. ous research efforts. At the same time, we on the 1990 Houst This ban is consistent with international must also educate and prevent. The disease Summit efforts to further isolate the Noriega is spread through known ways, and it is December 1, 1989 regime, which is currently shunned by the clear that education on the facts is our best democratic nations of Latin America and means of combating AIDS at this time. President Bush will around the world. The resolution of the re- Finally, we must remember those Ameri- of the seven major cently concluded General Assembly of the cans who have become infected with the July 9-11, 1990, in ] Organization of American States was sharp- nomic summit is th virus, including some who may be unaware ly critical of the Noriega regime and is only leaders of the world one example of the international condem- of their infection. These people need our mocracies to discuss nation of Noriega. The President has made help and our compassion. Our hearts go out review other key in it very clear that there will be no accommo- to those afflicted, as our heads work to- ticipating in the Hot dation with the illegal Panamanian regime. wards finding solutions. In the meantime, will be Canada, the The United States will continue various we must continue to educate those around Germany, France, I efforts designed to assist the Panamanian us regarding the prevention of this terrible Kingdom, the Unite people in their endeavor to bring about disease. mission of the Europ Noriega's departure and the establishment The President has of democratic institutions responsive to the Malek to serve as I will of the people. with the personal r The United States regrets the hardships that capacity he wi which Noriega has brought to the people of Statement by Press Secretary Fitzwater for and staging of th Panama, who deserve to be led by a gov- on the Attempted Overthrow of the currently president ernment of their choice. The United States Philippine Government and cochairman of will continue to exercise its rights and November 30, 1989 mercial Group. comply with its obligations under the The President ha Panama Canal Treaties and looks forward to We reiterate the unequivocal support of ard T. McCormacl a time when it can work closely with a the U.S. Government for Philippine democ- State for Economic democratically elected, constitutional gov- racy and the government of President Cor- as his Personal Re ernment in Panama, dedicated to serving azon Aquino. We strongly condemn the for preparation of p the interests and welfare of the Panamanian effort to destabilize the elected Philippine nomic summit. Mr. people. Government. According to U.S. law, all U.S. similar capacity dur: foreign assistance to the Philippines would Paris. be suspended if the elected Government of the Philippines were removed by a military Statement on the Observance of World coup. Points of Light Re AIDS Day November 30, 1989 The President name uals and institutio On December 1, World AIDS Day, there commitment to ma will be a commemoration in Washington to Statement by Press Secretary Fitzwater central to the life a remember all those with HIV infection and on United States Military Assistance for can. The daily rec all who have died from it. The end result of the Government of the Philippines tended as a nation this infection, AIDS, has been diagnosed in December 1, 1989 order to every singl over 112,000 people in this country as of difference in the 1 October 1989, and 65,000 people have died At the request of President Aquino, the since the beginning of the epidemic. President has authorized U.S. military assist- The President ex Though the problem is great and taxing our ance to the Government of the Philippines the following: health care system now, far greater difficul- in defending itself against a coup attempt. November 27 ties await us in terms of human suffering This assistance is intended to allow the Dr. William and Mr and provision of health care. democratically elected government of the City, OK. The rec We have committed resources at an un- Philippines to restore order. The President operate a free med precedented rate to HIV-related research of also is determined to protect the lives of serious medical pr all kinds. Though there is no cure for AIDS Americans in the Philippines. sclerosis. The clini 1856 Feb. 9 / Administration of George Bush, 1989 Speech Coness Administration of George Bush, 1989 / Feb. 9 will back up those who put their lives on oil. And when those with the most promise We have a moral contract with our senior We face a massive task in cleaning up the the line every single day-our local police can be tapped safely, as with much of the citizens. And in this budget, Social Security waste left from decades of environmental officers. Alaska National Wildlife Refuge, we should is fully funded, including a full cost-of-living neglect at America's nuclear weapons My budget asks for beefed-up prosecu- proceed. But we must use caution. We must adjustment. We must honor our contract. plants. Clearly, we must modernize these tion, for a new attack on organized crime, respect the environment. And so, tonight We must care about those in the shadow plants and operate them safely. That's not and for enforcement of tough sentences— I'm calling for the indefinite postponement of life, and I, like many Americans, am at issue; our national security depends on it. and for the worst kingpins, that means the of three lease sales which have raised trou- deeply troubled by the plight of the home- But beyond that, we must clean up the old death penalty. I also want to make sure that bling questions, two off the coast of Califor- less. The causes of homelessness are many; when a drug dealer is convicted there's a mess that's been left behind. And I propose nia and one which could threaten the Ever- the history is long. But the moral impera- cell waiting for him. And he should not go in this budget to more than double our cur- glades in Florida. Action on these three tive to act is clear. Thanks to the deep well rent effort to do so. This will allow us to free because prisons are too full. And so, let lease sales will await the conclusion of a of generosity in this great land, many orga- the word go out: If you're caught and con- identify the exact nature of the various victed, you will do time. special task force set up to measure the nizations already contribute. But we in gov- problems so we can clean them up, and But for all we do in law enforcement, in potential for environmental damage. ernment cannot stand on the sidelines. In clean them up we will. I'm directing the Attorney General and my budget, I ask for greater support for interdiction and treatment, we will never We've been fortunate during these past 8 the Administrator of the Environmental emergency food and shelter, for health win this war on drugs unless we stop the years. America is a stronger nation than it demand for drugs. So, some of this increase Protection Agency to use every tool at their services and measures to prevent substance was in 1980. Morale in our Armed Forces disposal to speed and toughen the enforce- abuse, and for clinics for the mentally ill. will be used to educate the young about the has been restored. Our resolve has been ment of our laws against toxic waste dump- And I propose a new initiative involving dangers of drugs. We must involve the par- the full range of government agencies. We shown. Our readiness has been improved. ents. We must involve the teachers. We ers. I want faster cleanups and tougher en- must confront this national shame. And we are at peace. There can no longer must involve the communities. And, my forcement of penalties against polluters. There's another issue that I've decided to be any doubt that peace has been made friends, we must involve ourselves, each In addition to caring for our future, we mention here tonight. I've long believed more secure through strength. And when and every one of us in this concern. must care for those around us. A decent that the people of Puerto Rico should have America is stronger, the world is safer. One problem related to drug use de- society shows compassion for the young, the the right to determine their own political Most people don't realize that after the mands our urgent attention and our con- elderly, the vulnerable, and the poor. Our future. Personally, I strongly favor state- successful restoration of our strength, the tinuing compassion, and that is the terrible first obligation is to the most vulnerable- hood. But I urge the Congress to take the Pentagon budget has actually been reduced tragedy of AIDS. I'm asking for $1.6 billion infants, poor mothers, children living in necessary steps to allow the people to in real terms for each of the last 4 years. for education to prevent the disease and for poverty-and my proposed budget recog- decide in a referendum. We cannot tolerate continued real reduc- research to find a cure. nizes this. I ask for full funding of Medicaid, Certain problems, the result of decades of tion in defense. In light of the compelling If we're to protect our future, we need a an increase of over $3 billion, and an expan- unwise practices, threaten the health and need to reduce the deficit, however, I sup- new attitude about the environment. We sion of the program to include coverage of security of our people. Left unattended, port a 1-year freeze in the military budget, must protect the air we breathe. I will send pregnant women who are near the poverty they will only get worse. But we can act something I proposed last fall in my flexible to you shortly legislation for a new, more line. I believe we should help working fami- now to put them behind us. freeze plan. And this freeze will apply for effective Clean Air Act. It will include a lies cope with the burden of child care. Our Earlier this week, I announced my sup- only 1 year, and after that, increases above plan to reduce by date certain the emissions help should be aimed at those who need it port for a plan to restore the financial and inflation will be required. I will not sacrifice which cause acid rain, because the time for most: low-income families with young chil- moral integrity of our savings system. I ask American preparedness, and I will not com- study alone has passed, and the time for dren. I support a new child care tax credit Congress to enact our reform proposals promise American strength. action is now. We must make use of clean that will aim our efforts at exactly those within 45 days. We must not let this situa- I should be clear on the conditions at- coal. My budget contains full funding, on families, without discriminating against tion fester. We owe it to the savers in this tached to my recommendation for the schedule, for the clean coal technology agreement that we've made with Canada. mothers who choose to stay at home. country to solve this problem. Certainly, coming year: The savings must be allocated We've made that agreement with Canada, Now, I know there are competing propos- the savings of Americans must remain to those priorities for investing in our future secure. Let me be clear. Insured depositors that I've spoken about tonight. This defense and we intend to honor that agreement. als. But remember this: The overwhelming We must not neglect our parks. So, I'm majority of all preschool child care is now will continue to be fully protected. But any freeze must be a part of a comprehensive provided by relatives and neighbors and plan to refinance the system must be ac- budget agreement which meets the targets asking to fund new acquisitions under the Land and Water Conservation Fund. We churches and community groups. Families companied by major reform. Our proposals spelled out in Gramm-Rudman-Hollings law who choose these options should remain eli- will prevent such a crisis from recurring. without raising taxes and which incorpo- must protect our oceans. And I support new The best answer is to make sure that a mess rates reforms in the budget process. penalties against those who would dump gible for help. Parents should have choice. like this will never happen again. The ma- And for those children who are unwanted I've directed the National Security Coun- medical waste and other trash into our jority of thrifts in communities across the cil to review our national security and de- oceans. The age of the needle on the beach- or abused or whose parents are deceased, Nation have been honest. They've played a fense policies and report back to me within es must end. we should encourage adoption. I propose to major role in helping families achieve the 90 days to ensure that our capabilities and And in some cases, the gulfs and oceans reenact the tax deduction for adoption ex- dream of home ownership. But make no resources meet our commitments and strat- off our shores hold the promise of oil and penses and to double it to $3,000. Let's mistake, those who are corrupt, those who egies. I'm also charging the Department of gas reserves which can make our nation make it easier for these kids to have parents break the law, must be kicked out of the Defense with the task of developing a plan more secure and less dependent on foreign who love them. business; and they should go to jail. to improve the defense procurement proc- 180 181 June 8 / Administration of George Bush, 1989 Administration of George Bush, 1989 / June 8 proper avenue there, but I cannot-and you want to have-you said mandatory for ask a good question-I simply cannot tell everybody? Visa Extensions for Chinese Students posal. And we've done exactly that. The you with authority who is calling the shots Q. Yes. Or at least an end to the anonym- Q. I have one followup. There are 20,000 proposal we made at NATO has unified the there today. ity of it? Chinese students in the United States. alliance, and some of the leaders told me Q. Let me follow by asking you this then. The President. No, I don't favor that. I The President. Yes. that it's more unified than it's been in histo- When you were in China earlier in the think there is a certain right to privacy that Q. Many of them have spoken out. Are year, you met with Li Peng, and I believe ry. We've made a good proposal now, and I we should respect. And so, in terms of ano- you told him that China was exempted you prepared to grant them political asylum hope the Soviets will take it on good faith, nymity, I would like to suggest that records in this country, should these from your policy review because you knew and I am encouraged by the response so China, you understood China. Have you of that nature should be kept private. The President. They're not seeking far. There's a lot of suffering for AIDS victims asylum. I'll tell you why I answer the ques- been let down personally? Have you been Having said that, in dealing with the misled in any way? There's a lot of human tragedy that we tion that way. They're not seeking asylum. Soviet Union, I am going to continue to The President. I feel a certain sense of haven't really focused on too much. And I We had four of them in the other day. And keep my eyes wide open. I will also say I personal disappointment. But they weren't think something less than very discreet han- the first thing that one of them-Jia Hao- want to see perestroika succeed. I want to said, "I love my country." And he wants to exempt from the norms of behavior that are dling of that information would not be help- see it succeed, not fail. And I told Mr. Gor- accepted internationally in terms of armed ful. But do I encourage people to come for- go back to his country. But what I have bachev that one-on-one last fall at Gover- ward and talk to their doctors and all about done is extend the visas so that people are people don't shoot down unarmed students. nors Island. So, I don't think he believes Nobody suggested that. partners that may affect others? Yes, I do not compelled to go back to our country. that I view this as some kind of a Cold War He's not seeking asylum. This man is not There was an interesting point in there- think you need that kind of frankness, and I relationship, or that I want to see peres- going to turn his back on his own country. and I don't want to delve into the detail of do favor certain kinds of testing. He wants to change things. But he also troika fail. He did say that he felt there private conversations-but one of the Chi- Lesley [Lesley Stahl, CBS News]? wants to know that he is going to be safe, were some elements in this country that nese leaders, a very prominent name, told and I don't blame him for that. So, it's not a did. But I hope that now he knows that I me, "We want change, but people have to China-U.S. Relations question of all these people-asylum is a don't look at it that way. understand it's very complicated here, how Q. Mr. President, back to China. There legal status, and that's not what they're Q. Well, let me just follow up. Do you fast we move on these reforms. We've come are reports tonight that the Government looking for. accept that he is sincere in terms of-are a long way." And indeed, they did move there has begun rounding up the student Q. light of the student roundups. I you operating on the assumption that he is dramatically faster on economic reforms mean, if they face— sincere when he says he's interested in new than I think any of us in this room would leaders, who face at the very least, persecu- The President. I think it's appalling, and thinking in international affairs? have thought possible. tion, at the most, possibly charges of treason so I would simply say that what we've al- The President. He's already demonstrated But what hasn't caught up is the political and whatever punishment that will bring. ready done would say to these people, You that he's interested in new thinking. Who reforms and reforms in terms of freedom of You have talked tonight about your strong desire to keep this relationship going and to don't have to go back. But I'm not going to would have thought that we would sit here expression. The freedom of press caught up ask them to turn down the flag that they and, on television, see a relatively lively a little bit; but it hadn't gone, obviously, keep the dialog and all our business as usual love and turn their back on China. These debate? It's nothing like our Congress, but near far enough. And now there's martial moving forward. If the- are patriotic young people who fear be- it had some similar aspects to it. And so, I law and censorship. But we were cautioned The President. Not all of them. Excuse cause of seeing their own brothers and sis- think he has already demonstrated his com- on that visit about how fast China could the interruption- ters gunned down. But they're not seeking mitment to change and to reform. move. Some of it was economic, and clearly, Q. Well, except for the military- asylum. They don't want to flee China; they But there's ways now to solidify these some of the message had to do with how The President. Yes. want to help change China. changes. They have 600,000 troops, and we fast they could move politically. Q. Except for the military, sir. If we find Soviet Union have 305,000. And I made an offer to him. I AIDS Testing out that the people who perpetrated the said the best way to guarantee stability and Q. Mr. President, turning your attention killings in Tiananmen Square and who were Q. Mr. President, we can discuss another less warlike attitude is to go to equal num- to a matter that's devastating here at home rounding up these students are running the Communist country for a while. Your atti- bers. And they are being asked to take out tude towards the Soviet Union seems to many, many more troops than we are. But and all over the world, the question of Government, can the United States main- AIDS. Respected experts are now starting tain fairly normal relationships with them, have shifted a bit since you became Presi- I've said, What's wrong with being equal? given our aim to foster human rights and dent, from deep skepticism to seeming ac- The United States will have 275,000 troops to suggest that instead of the anonymous testing that has existed in the past, there promote democracy? ceptance of their intentions. Do you now deployed, and you, sir, will have 275,000. accept Mr. Gorbachev's sincerity in regard should be mandatory reporting of new cases The President. It would make it extraor- So, here's a test now. Nobody can argue the to his pledge of new thinking? And can you by name and numerous followups on sexual dinarily difficult. But the question is so hy- inequity of that, particularly since we've tell us a little bit about why you've put aircraft and helicopters and these other partners and needle-sharing partners. Do pothetical that I'm going to avoid answer- changed. categories on the table. you favor such an approach, sir? ing it directly. But anything that codifies The President. I don't think it's shifted as The President. I've spoken at an interna- the acceptance of brutality or lack of re- And I am inclined to think that if I do my much as you think, Michael [Michael Gelb, tional AIDS conference, at which I was work properly and we keep NATO moving spect for human rights will make things Reuters]. I don't think it's shifted as much. forward on this quick timetable, that we roundly booed, 2 years ago or so, advocat- much more difficult. There's no question What I did was to say, We need a time to can succeed. And if we do, he will once ing certain kinds of testing. And I don't about that. make some prudent investigation and dis- again have demonstrated his desire for covery and then to go forward with a pro- change. 868 869 Bushia George Bush for President CONTACT: ALIXE GLEN FOR IMMEDIATE RELEASE (202) 842-1988 Tuesday, June 28, 1988 STATEMENT BY THE VICE PRESIDENT ON THE AIDS COMMISSION REPORT The Commission Report is a landmark analysis of the problems facing our country due to the AIDS epidemic. There is little doubt that it will be the benchmark for future discussions. Admiral Watkins, the Commission members and staff have done an excellent job. They have proved their critics wrong. Many pundits believed that the Commission would fail, yet Admiral Watkins and his colleagues have set the right tone for how we should approach AIDS in the months and years to come. I am particularly pleased that the Commission recognizes the need for patient notification and wide-spread testing as a means to limit the spread of AIDS. Such programs will be ineffective without being coupled with strict confidentiality and anti-discrimination provisions. I am also encouraged by their understanding that the AIDS crisis and the drug crisis are intertwined. We will be unable to stop the spread of AIDS if we do not stop the spread of drug abuse. The Commission identified the problems confronting our scientific and medical communities in the search for a cure, vaccine and treatment of those with the disease. The Commission's recommendations to make these efforts more effective should be given the highest priority. It is our duty to do all we can, not only to find a cure and a vaccine, but also to make sure we never create a climate in America where friend turns against friend, where countrymen turn against countrymen. # # # 733 15TH STREET, N.W., SUITE 800, WASHINGTON, D.C. 20005 TELEPHONE: (202) 842-1988 Paid for by George Bush for President the peak came in the third week of Polio Prognosis September. In 1949, which set the record of 42,366 cases, polio reached its height No one could convince Mr. and Mrs. in the third week of August. Donald F. DeMars that 1951 wasn't a bad year for polio. Within a few days the Live Cortisone Van Nuys, Calif., couple (see cut) had seen six of their eight children stricken As a manufacturing process it wasn't with the disease. But at the week end worth an inflated nickel. But as a scien- officials of the National Foundation for tific achievement. fellow chemists agreed, Infantile Paralysis were far from certain two teams of Harvard researchers whether this year's occurrence of polio headed by Profs. Robert B. Woodward would approach the record-breaking epi- and Louis F. Fieser had scored one of demics of 1949 and 1950. the triumphs of the century. Some very sore spots had already ap- The accomplishment, announced last peared. Polio was raging in Colorado, week in the Journal of the American particularly around Denver and Pueblo, Chemical Society, was the complete syn- and in the Caddo and Red River parishes thesis of cortisone. Now for the first time of Louisiana. Mississippi was having the chemists could. if they so desired, make worst outbreak in years, centered in Sun- the drug from its basic elements-carbon, flower County in the delta country. Mil- hydrogen, and oxygen. waukee, with the worst epidemic in its Meanwhile, in the same journal. chem- history, reported twice ás many cases as ists of Merck & Co. reported that they at this time last year. The number of could synthesize cortisone from four nat- cases was rising in the Salt Lake City ural substances much more abundant National of area. And Texas and California. endemic than the OX bile currently most used as Sweat: A biochemical lever areas, were suffering from their usual the starting point for commercial produc- summer upswing. tion. The four were: ergosterol, from glands of cattle. After two years of But as of Aug. 4. 1951, polio was yeast; diosgenin, from the Mexican yam*; work Dr. Max K. Sweat (rhymes running behind 1950-6.845 cases re- stigmasterol, from soybeans: and choles- let), biochemist of the National Insti ported as compared with 7.298 at the terol, which can be extracted from wool of Health, last week reported suc same time last year. The foundation fat or the spinal cords of cattle. Dr. Sweat first grinds the ad judged that the present situation is "not Meantime, scientists of the United glands (which look like frozen shrit abnormally serious, nor is the rate abnor- States Public Health Service had been off He then centrifuges the pinkish "gl mally low." Until the epidemic reaches on another tack: making cortisone or its getting a clear pink-tinged fluid. its peak, no one can tell how serious it natural counterpart from the adrenal finally small crystals of an renzy will become Last year when 33,351 cases prótein which spurs biological act *The raw material used by Syntex, Inc., of were reported throughout the country, Mixed with stigmasterol from Mexico City (NEWSWEEK, July 16 beans (see above), the enzyme to work and produces small amoun hydro-cortisone, a near cousin of sone and just as good if not be Sweat says frankly: "It is quite CC that synthetic methods will be the mary source of the [cortisone-like] mones. The main contribution of work is that it helps us understand of the intricate mechanisms OCCU inside the adrenal glands. He is fascinated particularly by key enzyme-"a wonderful and un substance that acts like a lever in ducing the hormone. It is probably first enzyme to be identified in the ing of a hormone." Sweat has reason to be proud. enzyme accomplishes in one fifteen ute step what takes 27 steps in current commercial process. More esting is the conjecture that the en itself might some day be given to people to help them speed up natural hormone production and fight disease. Healthmanship Stephen Potter, author of "Games ship" and "Lifemanship," the defi Associated Press works on psychological warfare ap Richard DeMars, aged 3, with parents: How many will follow him? to polite society, last week came out 52 News NEWSWEEK 8-20-51 Services of Mead Data Central PAGE 2 3RD STORY of Level 1 printed in FULL format. Copyright (c) 1989 The Washington Post October 8, 1989, Sunday, Final Edition SECTION: METRO; PAGE D3; COURTLAND MILLOY LENGTH: 737 words HEADLINE: A Fabric of Love, Pain, Anger BYLINE: COURTLAND MILLOY BODY: I did not expect to find anybody I knew memorialized in an AIDS quilt on the Ellipse yesterday. I did not expect to cry. I'd been to the Vietnam Veterans Memorial wall, seen cemeteries filled with rows of cold gravestones, and pretty much figured that there was nothing to do for the dead except pay my respects. But somehow these 10,848 panels of cloth rocked my soul in a way that granite never did. So delicate and vulnerable to nature's elements, each fiber became the very embodiment of the AIDS victim that it represented. There were squares with poems for the babies who had died, squares with photographs of innocent children woven into them. A black baby, dressed in a new pink dress and matching bonnet --- dead of AIDS before she could grow out of her bell shoes. There was a square with a row of mournful teddy bears, stitched onto a window sill, crying into the night for a man called "Boo Boo," whose photograph was sewn in near them. "We whispered 'We miss you!' = said the little bears. "But there was no reply. We sat by the window, and heard the moon sigh." Thoughtful words and pictures sewn onto a piece of cloth, breaking the hearts of all who saw them. Those weren't just little bears speaking -- but children, mothers, fathers, sisters, brothers, friends and lovers who have been deeply hurt by death. A sister of a man who had AIDS sat at the edge of a square she had sewn, 50 sorry that she had not spoken to him in the years before the disease took his life. Now he was gone. Would he please forgive her, she prayed, leaving a handful of roses as she tearfully staggered away. People who thought they were just taking a curious stroll, such as I, suddenly found themselves wiping away tears. I had forgotten about my fellow journalist, ABC newsman Max Robinson. But a panel honoring him was there. I had forgotten about Melvin Boozer, the first black president of the Gay Activist Alliance. But there was cloth for him too. There were even squares for people whom I hadn't even known were ill. Suddenly, I discovered they were dead. Among the living were heartwarming people such as Ray Kinlock, whose job is to repair damaged squares. Surely it would be easier for him to handle his feelings, having seen the squares hundreds of times. It was. LEXIS® NEXIS® LEXIS® ® NEXIS ® Services of Mead Data Central every jun PAGE (c) 1989 The Washington Post, October 8, 1989 fablic its "I don't fight it. I just cry --- all the time," Kinlock said. "It is so sad. I have made quilts for 30 friends who have died. I can see a certain color, a certain fabric or read a certain poem, and something breaks inside me. Every colors, time I see the panel of Baby Jessica, the first infant to die of AIDS, I am moved to tears." its sourl. He added, "I think of the quilts as educational art, and notice how it has brought so many people together, how it has helped reduce the fear." two Evelyn Martinez, organizer of the quilt repair crew, also worked feverishly no to keep the panels looking like new. For her, there was no point trying to keep her emotions in check either. alites are "Sometimes I feel 50 guilty, like I am not doing enough," she said. "I work full time on the panels, but I always feel like they are not going to hold up. It's as if they were human beings. As they get older, they begin to fall apart. But if you can fix it, restore it to beauty, that is such a satisfying feeling." Joseph van Es-Ballesteros, the logistics coordinator for the AIDS quilt, a bridge was not totally satisfied. Pointing angrily beyond the quilt toward the White House, he criticized the federal government's response to the AIDS crisis. fetween "The inaction and insincerity that comes from the president, as well as Congress, is abhorrent," he said. "The compassion and caring on the part of the number friends and family is wonderful, but without serious action on the part of our leaders, it won't amount to anything." It and the Philip Pannel, who worked at an AIDS awareness table for the United Black Fund, was angry too. Very few black people, he noted, had bothered to make squares or visit the display, even though blacks have a higher rate of AIDS infection than whites. "I guess if they don't care about AIDS victims when they are alive, no reason to expect they'll care once they are dead," he said. The displayed squares represented only 18 percent of those who have died of AIDS in the United States. Yet, on and on they went, for 14 acres, SO that after 49 miles of walking around the cloth, the effect of a major catastrophe was more than apparent. It was overwhelming. TYPE: COLUMN SUBJECT: ACQUIRED IMMUNE DEFICIENCY SYNDROME; DISTRICT OF COLUMBIA; DEATH AND DEATH CEREMONIES LEXIS® NEXIS® LEXIS® NEXIS Services of Mead Data Central PAGE 4 4TH STORY of Level 1 printed in FULL format. Copyright (c) 1989 The Washington Post October 8, 1989, Sunday, Final Edition SECTION: METRO; PAGE D3 LENGTH: 544 words HEADLINE: AIDS Quilt Captures the Fear Behind the Loss; Panels That Don't Identify Loved Ones Serve as Reminder of Public Stigma BYLINE: Brooke A. Masters, Washington Post Staff Writer BODY: The Names Project AIDS Memorial Quilt is above all about preserving people's identities. From the gold lame' rectangle dedicated to Broadway choreographer and director Michael Bennett to a calico quilt pieced together by the friends and relatives of Helen Beckey, each of the 10,848 panels on display at the Ellipse this weekend serve as handsewn reminders that AIDS has killed individuals. Throughout the weekend, the names of the people memorialized on the 14-acre quilt and of those who have died too recently to have their own squares boomed overhead, read over a loudspeaker by activists and family members. But amid all the emphasis on names and identity, many people have sought anonymity. Organizers estimated that up to 10 percent of the panels are not embroidered with full names. Fifty-three of the squares are dedicated only to Jims or Jimmys, and 57 memorialize anonymous Johns and Johnnys. Then there was the panel for Robert W. Pinned across Robert's last name was a blue felt strip embroidered with the words "Family fear removed this name. Love can remove this patch." Quilt visitors who have lost family members to AIDS said they understand such fear. When Michael Hackney contracted AIDS, "There was no question we were going to take care of him," said his mother, Edith Hackney, who had come from Philadelphia to see Michael's panel in the quilt. "If people didn't want to come to our house = Her voice trailed off and then strengthened. "The hardest part was when ambulance drivers would come with hoods on like the Ku Klux Klan." Betty Berge said the death of her son, John Karl Berge, from AIDS has made her sensitive to fear and ignorance about the disease. "I live in Front Royal, and AIDS is not a very popular disease there," Berge said. "There are a lot of people who need comfort who don't get it because they are afraid." LEXIS® NEXIS® LEXIS® NEXIS ® Services of Mead Data Central PAGE 5 (c) 1989 The Washington Post, October 8, 1989 Since her son's death two years ago, Berge has joined a group for people infected with the AIDS virus and their families. The group keeps its membership confidential, for fear of reprisals, she said. After writing her son's name and the words "Your death was a teaching of love" on one of the panels set aside for visitors' signatures, Berge said, "I'm going to stay in Front Royal and [try to] reach enough people." The death of their son, Robert Shuman, galvanized Alma and Jim Shuman to fight for AIDS awareness in their home state of Oklahoma. "We've been making strides. Now when one of our young men passes away, they say in the paper he has AIDS, = said Alma Shuman, who wore a "Tell Tulsa" button. Many quilt visitors said Project Names helps counter the stigma they have encountered because of AIDS. "Where else could you see people walking around with reverence and despair all wrapped into one?" said Bob Krieger of New York, who sat by his dead lover's panel, listening to a tape of the man singing. "At one time, you want to shake your fist to the heavens and thank God." Act Up, a New York-based group, tried to capitalize on that impulse and yesterday's Housing Now! march by organizing a protest in front of the White House. About 250 people demanded housing for AIDS patients and chanted slogans such as "Bush, Bush, you can't hide. We charge you with genocide." GRAPHIC: PHOTO, THE AIDS QUILT'S SHOWING AT THE ELLIPSE, WHICH ENDS AT 5 P.M. TODAY, MARKS THE LAST TIME THE QUILT WILL BE SHOWN IN ITS ENTIRETY BECAUSE OF ITS SIZE. BILL SNEAD TYPE: DC NEWS SUBJECT: DISTRICT OF COLUMBIA; ACQUIRED IMMUNE DEFICIENCY SYNDROME; DEATH AND DEATH CEREMONIES flanket of lone spreading out accross embracing ameria the hurt LEXIS® NEXIS® ® LEXIS® NEXIS® R Services of Mead Data Central PAGE 6 5TH STORY of Level 1 printed in FULL format. Copyright (c) 1989 The Washington Post October 7, 1989, Saturday, Final Edition SECTION: METRO; PAGE B3 LENGTH: 573 words HEADLINE: Stories of Love, Sorrow Blanket Ellipse; Quilt Commemorating Those Who Have Died of AIDS Covers 14 Acres in Final Full Display BYLINE: Kathy Ann Waterman, Washington Post Staff Writer BODY: Chuck Egger sat cross-legged on the grass of the Ellipse yesterday, embroidering a love letter on a piece of canvas the size of a grave. "Dear Dick," the red thread spelled out, "I love you. I will always love you. I never got tired of saying that even after 8 1/2 years. I'll remember the life we built the good times and the bad." Egger's lover, Dick O'Doniel, died of AIDS a few months ago. Egger is one of thousands of people across the country who made panels for the Names Project AIDS Memorial Quilt, which is on display this weekend in Washington for the last time in its entirety. The quilt now covers all 14 acres of the Ellipse, and with more panels still arriving from as far away as Europe, Africa and Australia, there will be no space large enough to show it in the future, organizers said. The 10,848 panels represent 18 percent of all U.S. AIDS deaths, according to the Names Project. Like scrapbooks of memories, but containing more than photographs and letters, the panels are laden with the unusual and the commonplace: locks of hair, wedding rings, a beaded hat, cremation ashes, a sequinned parrot, medals, sheets of music, ballet shoes. Egger attached O'Doniel's leather jacket, teddy bear and picture of their Shar-pei dog onto the canvas. Some panels bear only the name of the person who died, the dates of birth and death and perhaps a brief "I miss you" or "I love you." Others show painstaking detail, days of painting, cutting, gluing, stitching. One memorial is a collection of neckties plus two Campbell's soup labels. Another is made of a pink baby blanket with a child's frilly dress attached to the center. It belonged to a girl named Maria Prophet, who died of AIDS in 1982 at age 4. Happy scenes of satin rainbows and velvet trees, silk flowers and balloons contrast with grim satire. One panel depicts a pair of hands gripping a ladder. A dagger, dripping red, pierces the right hand. On the dagger is written R. Reagan. LEXIS® ® NEXIS® LEXIS® NEXIS gesdeur V gurbbrud L60' UTSL062 FUS LIGHT WSWQ" ON FPG 12 MLIFIGU " MTCH BLTW 287146 046 beusy qubicca S beft 06 WSUQ2 aribbind 9 T99431 gobbs LOSSE OK 28614 LETUPOMP Rug ABIABF FLEER' 2TJK +JOMEL? 504 performs 1083 3f 586 1" FUS If payouitsq fo y BELT uswag 491.19 probuer* MUD 9769 of VIDE IB PROPERT 12 #BGS of 5 bink paph MIRP a CUITO,E ELIJIA 46622 fir OUG removie] :2 I currection U4 broz FMO sonb T906T2' 185917 qgive 04 betwgind* charrud* Byncod* appropted: QERIP swq betwer 5 PLISE at WIT? Non., 04 I TOAG Addr, OFFERE 2.10M 2016 bruefe DASL DUJÀ FWG USWS of 4NG DEL200 MND 91691 FUE 99152 01. BILES 3WQ PS91 BWQ biccase 04 IDSTL god 0.110 FUE CSUARE' 206622 of MARIC PRITED BWOGE" FUBGL 0,DONIG) . 2 2 TESINEL Oscker' requir NETT' MEQUINO Liude' 9 peaced port 92W62 3 address become W643]2' FUG benefe 366 TSQ6N MICH FVG current 300 FUE commonbrees: JOCK? or TIKE SCLYDOOOK? of PAT coupsiving was figu 904 CO FWG HLOJECF' INS 10 "RYB DBUGJ2 CELLERENT 18 heleave 06 9TT 0"2" VIDE despur' accounted NO abscs evendy por 2NOM If (11 TUB themse' 2910' 24133 SELIATUD FLOW 02 +96 SM97 92 Encobs' VILICE 9WQ CHSLS MIJI DE LUE darit wen COAGLE STJ 1₹ 90557 of rus Bild MICH MOLE bouere tol FUE 1972 CITS TU II2 surilact THE ИЗШЕР 6407scf VIDE GATIF* MUTCH 12 OR grabjsh fille III EUDEL 12 006 of DL beobys SCLORE FUS commits Mpr WBQ6 beusre ton Eddet, TOASL BICK 0,000J6J' QI6C of VIDE 9 65M WOULDS são: ME CHITE CUE Booq FIWER 3WQ FPG psq". ? HEASL any STL5Q It assind FLSE EASU 96566 R INS AGELT" I.JT LEWEROGL FINE ITAB D691 DICK'. THE usq onf' aI JOAS Ann: T MITT STMSAR TOAG home tod F JOAS TEREL on 12 DIECE of CHILADE FN5 eise OF 3 BLEAS CHACK Edder JSF OR spc Buaza of FME EITIDEE CODA: BACIME: K3CUÀ YON 602f 26916 MLIFOL EAST Dishred 09111 JW026 MNO H3A6 DIEQ ot VIDE COMGLE 18 70.52 TH ETHST HEYDERING: 3106162 of ГОЛЗ* BULLOM BIBUKES ETTIDES: ГЕИРТН: 213 morga PECLION: NE18.1) 6VPE 83 OCCOOSL 5' JABA' 29:40:3A' t: ETWBT EQICION cobklider (C) TOBA LUS 6084 21H PROTE 04 [MAG] / briwing TO LPFT byee Q Services of Mead Data Central PAGE 7 (c) 1989 The Washington Post, October 7, 1989 A reading of names of the dead went on all day yesterday. Singer Dionne Warwick was a volunteer reader, as was actress Betsy Palmer. People clapped when they took the stage, but it was the dead and not the living who claimed center stage. About 10,000 people moved slowly along the 49 miles of black canvas walkways that separate sections of the quilt. Some stooped to leave roses or carnations on the quilt. Two men embraced and wept on each other's shoulder. Tears came freely yesterday. Names Project volunteers kept packets of tissue paper in their pockets. "Many people have not had the chance to grieve for their loved one," said Michael Persico, a volunteer. "For them, this is like attending a funeral or going to the cemetery." Through the tears, people were telling their favorite stories about the dead. Mary Jane Edwards, of California, laughed and cried as she told how her son, Gregory Connell, playfully tipped a plate of pie into his lover's face as he tried to get him to eat. Edwards, who helped form Mothers of AIDS Patients, said, "Gregory was so weak and thin but he never stopped laughing until the end when he could barely talk." Laughter was also sewn into the quilt. One panel told the story of a man named Brad whose ashes were scattered on the Mississippi River. The river was depicted on the cloth and the inscription read, "You always did want a free ride to New Orleans and now your ashes are doing this for you." GRAPHIC: PHOTO, THE 10,848 PANELS REPRESENT 18 PERCENT OF ALL U.S. AIDS DEATHS. SMITHSONIAN INSTITUTION; PHOTO, MARGARET THOMAS TYPE: DC NEWS, NATIONAL NEWS SUBJECT: ACQUIRED IMMUNE DEFICIENCY SYNDROME; DEATH AND DEATH CEREMONIES; DISTRICT OF COLUMBIA ENHANCEMENT: QUILT LEXIS® ® NEXIS® LEXIS® NEXIS® A formater of Natina Coulition 7 on LAIDS Dr. Lee - on original AIDS commission 450-500 CEOS pro - admistration taken deadership position on treating their amployees 1/2 million HIV - positive identified Persons (living). with AIDS NOT AIDS patients PWA hot homosexual gay HIV-inberted NOT AIDS employers only shield against AIDS people ending up on welfare must be thanked for haping people employee 1. congratulate businessman - they are panying the bill 2. discrimination - americans with Disabilities act 3. thank pts. of light - religious + community leaders, volunteers y. Education - for how - is are only weapon - -prevention AZT cost recently lowered from $12,000 to $ 8,000 per year Withdrawal/Redaction Sheet (George Bush Library) Document No. Subject/Title of Document Date Restriction Class. and Type 01. Notes Handwritten notes n.d. (b)(6) Re: President's AIDS speech; personal information redacted. (2 pp.) Collection: [Original OA/ID 06854] Record Group: Bush Presidential Records Office: Speechwriting, White House Office of Series: Speech File, Backup Subseries: Chronological Files WHORM Cat.: File Location: National Coalition on AIDS 3/29/90 [2] Date Closed: 10/15/2004 OA/ID Number: 13710-010 FOIA/SYS Case #: S Appeal Case #: Re-review Case #: 2004-2265-S Appeal Disposition: P-2/P-5 Review Case #: Disposition Date: AR Case #: MR Case #: AR Disposition: MR Disposition: AR Disposition Date: MR Disposition Date: RESTRICTION CODES Presidential Records Act - [44 U.S.C. 2204(a)] Freedom of Information Act - [5 U.S.C. 552(b)] P-1 National Security Classified Information [(a)(1) of the PRA] (b)(1) National security classified information [(b)(1) of the FOIA] P-2 Relating to the appointment to Federal office [(a)(2) of the PRA] (b)(2) Release would disclose internal personnel rules and practices of an P-3 Release would violate a Federal statute [(a)(3) of the PRA] agency [(b)(2) of the FOIA] P-4 Release would disclose trade secrets or confidential commercial or (b)(3) Release would violate a Federal statute [(b)(3) of the FOIA] financial information [(a)(4) of the PRA] (b)(4) Release would disclose trade secrets or confidential or financial P-5 Release would disclose confidential advice between the President information [(b)(4) of the FOIA] and his advisors, or between such advisors [a)(5) of the PRA] (b)(6) Release would constitute a clearly unwarranted invasion of P-6 Release would constitute a clearly unwarranted invasion of personal privacy [(b)(6) of the FOIA] personal. privacy [(a)(6) of the PRA] (b)(7) Release would disclose information compiled for law enforcement purposes [(b)(7) of the FOIA] C. Closed in accordance with restrictions contained in donor's deed of (b)(8) Release would disclose information concerning the regulation of gift. financial institutions [(b)(8) of the FOIA] (b)(9) Release would disclose geological or geophysical information PRM. Removed as a personal record misfile. alice anderson NAM AIDS BJ Stiles (bout contact) P-6,(b)(6) Bill Schambra Dr. antonio Novello James allen Dr. anthony Fanci NOVELLO " alo is Blusiase of finalies not a discuse of wen only Honosexualo done a good just of taking care - preventia Computersive one- stop came children - -orphans possible stignatized if parents die, but they dont are Rosenthal 3/18/90 have AIDS * NYT ines your ages AIDS orphans fed. Pedicitic tush force FAUCI: emphasize personal caring extraording amount into research trujing to reach minorities Nt/AIDS that have trouble getting any dind of care speaking there on 29kg as well AZT appoved by FDA for early use importert -> delays more severe symptoms, saves $ HIV infected not allowed into US without as waiver / Problem for S.F. world conf. P-6, (6)(6) BJ Stiles: Business & Union people Human Resource / Public affairs execs 450 people from around the country some working on AIDS, some have not/ indecided mosts hurge, mat'l. companies are 8:30 - 3-p.m. all state Insurance - host + intro business response to AIDS sime 1980 Lou Sallivan - over-view of epidemic overall admin. policy Fanci - update on research + treatment Jim Cumin - CDC - demographics of AIDS lowering official projections Q + A Bob Hass - Levi Strams - filler for POTUS POTUS Lunch Dick Munroe - Time Inc. CE any HIV+ appointees ? 1 Belinda Mason - HIV writing + Bush appointer to AIDS Commission Health Insurance issues Labor response to AIDS Renee Poussaint "Liring & Working with ADS Withdrawal/Redaction Sheet (George Bush Library) Document No. Subject/Title of Document Date Restriction Class. and Type 02. Notes Handwritten notes, Re: President's AIDS speech; personal n.d. (b)(6) information redacted. (3 pp.) Collection: [Original OA/ID 06854] Record Group: Bush Presidential Records Office: Speechwriting, White House Office of Series: Speech File, Backup Subseries: Chronological Files WHORM Cat.: File Location: National Coalition on AIDS 3/29/90 [2] Date Closed: 10/15/2004 OA/ID Number: 13710-010 FOIA/SYS Case #: S Appeal Case #: Re-review Case #: 2004-2265-S Appeal Disposition: P-2/P-5 Review Case #: Disposition Date: AR Case #: MR Case #: AR Disposition: MR Disposition: AR Disposition Date: MR Disposition Date: RESTRICTION CODES Presidential Records Act - [44 U.S.C. 2204(a)] Freedom of Information Act - [5 U.S.C. 552(b)] P-1 National Security Classified Information [(a)(1) of the PRA] (b)(1) National security classified information [(b)(1) of the FOIA] P-2 Relating to the appointment to Federal office [(a)(2) of the PRA] (b)(2) Release would disclose internal personnel rules and practices of an P-3 Release would violate a Federal statute [(a)(3) of the PRA] agency [(b)(2) of the FOIA] P-4 Release would disclose trade secrets or confidential commercial or (b)(3) Release would violate a Federal statute [(b)(3) of the FOIA] financial information [(a)(4) of the PRA] (b)(4) Release would disclose trade secrets or confidential or financial P-5 Release would disclose confidential advice between the President information [(b)(4) of the FOIA] and his advisors, or between such advisors [a)(5) of the PRA] (b)(6) Release would constitute a clearly unwarranted invasion of P-6 Release would constitute a clearly unwarranted invasion of personal privacy [(b)(6) of the FOIA] personal privacy [(a)(6) of the PRA] (b)(7) Release would disclose information compiled for law enforcement purposes [(b)(7) of the FOIA] C. Closed in accordance with restrictions contained in donor's deed of (b)(8) Release would disclose information concerning the regulation of gift. financial institutions [(b)(8) of the FOIA] (b)(9) Release would disclose geological or geophysical information PRM. Removed_as apersonal record misfile P-6, (b)(6) Dr. David Rogers - Vice Chairma - AIDS Commission In this nation there is only are way to deal will individuals who are sick! with dignity / compassion, care lack of descrimination Young surgeons not Caring for AIDS patients adequately - almost mailpractico Rogers ordered then to stop it. Changed behavior - not necesurily attitudes 1 they change more slowly Joan abrahmoon - Dr. Salk Polio - spread by oral ingestions human contact only fecal transmission in poor constries not insect aborn camphor -used long been described in Japan, the first epidemics of appreciable size reported there came in the Nineteen Thirties, and similarly this happened in a num- ber of tropical countries in the Thirties and Forties. Quite recently the new state of Israel experienced its first native epidemic. In other and populations, among which one could include the Philip- pines and certain North African coun- tries, poliomyelitis epidemics of any size among the natives do not yet seem to have been observed. Nevertheless the virus of poliomyelitis is present in such countries, for the rates at which United States and British troops con- tracted poliomyelitis in some of these "primitive, nonepidemic" areas during World War II bears witness not only to the presence of the virus but its frequency. The local native adult pop- ulation, on the other hand, did not suf- fer. They were apparently more im- mune than were the visiting soldiers. IF one attempts to explain all these situations in the light of our rather limited knowledge, one is treading on dangerous ground. Furthermore, one must inevitably deal with controversial points here, and perhaps deal with NYT them somewhat arbitrarily. Such an approach is usually adopted in the in- terest of simplicity, but it involves the Mag danger of over-simplification and therefore of a sacrifice of accuracy. which is one of the reasons why scien- tists as a group are at a disadvantage at the hands of journalists. There are. however, some generali- zations that one can make about poliomyelitis withia fair degree of con- fidence. We can regard it, as a contagious disease, of which the cause is known to be a virus discovered in 1908. The poliomyelitis virus is a repre- sentative of a whole race of ultra- microscopic agents known as filterable viruses, many of which are harmless To solve the riddle of poliomyelitis-A researcher uses a mass spectrometer, an electronic device for analyzing fluids. to man, while some others are deadly parasites. The main way in which the properties of viruses, or, indeed, the Mysterious, Paralyzing Disease very existence of certain of them can be demonstrated is by the cumbersome process of inoculating material pre- sumably containing the virus into an Doctors have learned much about the causes and treatment experimental animal and subsequently watching for the development of fever of poliomyelitis but prevention has proved a baffling quest. or other signs of illness in the animal. The pollomyelitis family of viruses is one of the most elusive members of H AS any real progress been made By JOHN R. PAUL Eighteen Eighties and Nineties did the this whole group, because with most recently in man's struggle to contagious character of poliomyelitis strains of this virus (and four distinct control or prevent infantile pa- so effective. such as the sulfonamides really became known. types are known), the only animals ralysis-or, as it IS more commonly and the antibiotics-penicillin. strepto- called today. poliomyelitis? The best The first observations of this type susceptible to infection are monkeys mycin. aureomycin, or chloromycetin, were made in Scandinavia. The disease and anthropoid apes, which are expen- one can do in reply to this question is to mention some of an already long thereafter was identified in periodic sive and often difficult to come by. It to point to certain gains which have and growing list. We can merely say epidemics in some regions, of which was discovered only in 1938 that one been achieved in other aspects of treat- that research is being conducted in an Scandinavia, northern Europe, the member of the family of poliomyelitis ing poliomyelitis. For instance, there effort to discover such agents for use United States and Canada, Australia viruses could also infect mice. have been improvements in what is in poliomyelitis. This. of course, grossly known as the after-care of patients and New Zealand are notable examples. understates the magnitude of these No longer was infantile paralysis a R who have been paralyzed. New meas- efforts. ESEARCH on the virus itself in- medical problem alone: by the turn of ures have been introduced for the re- dicates It to be one of the smallest of lief of pain during the acute disease, B the century it had become a public UT. if one cannot report medical health problem as well. the race, 80 small that it has not yet and for saving lives in the most serious been clearly defined under the electron achievements along these lines, it be- Did the behavior of the disease actu- cases. One might assemble quite a microscope. Some of its properties, on comes all the more important to ask: long list of such achievements. But in ally alter in this time, or does the What is known about poliomyelitis? the other hand, are definite. Poliomye- the field of prevention-no. paucity of records merely indicate that Why have doctors been so baffled by epidemics of poliomyelitis had escaped litis viruses are killed by heat, at tem- There is no vaccine available for it? is it & new disease-a twentieth- notice in the early nineteenth century peratures which also destroy bacteria. purposes of immunization. Nor is there century disease, as some people have and before? I would hesitate to make but unlike many bacteria they resist any specific drug known to be effec- said? pronouncements about this, but I certain chemicals or disinfectants such tive in acute poliomyelitis comparable The story is incomplete. but it is rather favor the view that its behavior as carbolic acid or chloride of lime. to those which in bacterial diseases are likely that infantile paralysis goes underwent PL change in certain geo- What is not known about these back as far as recorded human his- graphical areas. viruses is how to deal with them; how tory. Unfortunately, prior to 1800 the JOHN R. PAUL IS Professor of Preventive Indeed. we have witnessed something their spread can best be controlled, and records about "acute paralysis of in- Medicine at Yale's School of Medicine. like this in our own times, for, although how the disease can be checked in its fants" are scanty, and not until the scattered cases of poliomyelitis had earliest stages, Continued on Page 26, 18 Children stricken in an outbreak of poliomyelitis lie in respirators at Roanoke, Va. The Mysterious, Paralyzing Disease (Continued from Page 18) with poliomyelitis it appears not the case in some of the and a host of other practical that people may become in- remote parts of the world questions whose numbers only fected without ever having where the causative virus serve to emphasize our ignor been in contact with other penetrates only very occasion- ance. recognized cases of poliomyeli- ally and exposure comes less It is known that a certain tis. For its spread does not often. degree of immunity develops necessarily take place from In connection with the in the experimentally infected one severe and recognized case spread of poliomyelitis, there animal after its recovery to another. as occurs with are a number of other peculiar (with or without paralysis). measles. but often through features which might be re- an immunity which renders cases so mild as to escape garded as further evidence the animal resistant to acquir- recognition entirely. that the disease 18 undergoing ing a second infection due to some sort of evolution. In our the same type of poliomyelitis NE does not, in other grandparents' time in this virus, although this same ani- words. have to have the para- country and elsewhere polio- mal may acquire a second in- lytic form of the disease in myelitis was a disease of in- fection due to a different type fants - the true "infantile" of poliomyelitis virus. And it order to spread it to others. The evidence is quite convinc- paralysis." Indeed. according is more or less presumed that ing that during an average to physicians in New York this same situation holds true for man, although this pre- epidemic of poliomyelitis. City at the turn of the cen- those individuals who are ill tury. the malady was rarely sumption is not clearly estab- enough to become diagnosed seen in children over 6 years lished. as two attacks of polio- represent only a fraction- of age. Today we find, not myelitis in the same individ- perhaps 1 to 10 per cent-of only in the northern half of ual are rare. the total number of people in- this continent but more par- IT fected. This means that dur- ticularly in Scandinavia and is commonly agreed that ing an epidemic a child. or in other parts of Europe and poliomyelitis is generally even an adult: may unknow- Australia, that poliomyelitis is spread by contact between ingly harbor and transmit the not limited to infants but is persons, in somewhat the same virus to others. commonly seen in children of manner as diseases like mea- It also involves the corol- school age and teen age. Per- sles and mumps are spread. haps 25 per cent of the vic- lary, often unsuspected. that a But we cannot explain why tims in New England today very high percentage of adults climate and season exert such are 15 years or over. --roughly around 85 per cent 8. profound influence and why or more--have not only been epidemics of poliomyelitis exposed unknowingly to polio- T HIS change in the age level nearly always occur in the myelitis virus but have been of incidence has not taken summer rather than in the infected unknowingly with it, place everywhere. for the dis- winter in temperate climates. and have emerged from the ease is still concentrated Either something may happen experience not only unscathed among infants in certain prim- in the warm weather which but, indeed, the better for it itive countries-in contrast to enormously facilitates the because they have attained the other remote areas where spread and dissemination of some degree of immunity. the disease strikes adults— the virus throughout a com- and these include the areas munity or something may Thus adults usually do not happen in warm weather get poliomyelitis for the same where epidemics of poliomyeli- which makes some people reason that adults usually do tis have not appeared. Hence. not get measles; most of them one might suppose that this more vulnerable and far more have not only been exposed to alteration in the character of apt to acquire poliomyelitis than at other times of the it already but have actually the disease could somehow be had it. Evidence that most associated with some feature year. adult individuals living in the of our twentieth-century way And at this point we en- United States have been natu- of life-such as the changing counter another confusing fac- character and composition of tor. One can readily under- rally immunized by exposure populations, or the curtail- stand that so-called communi- to poliomyelitis finds support ment in the size of families. cable diseases are transmitted in the fact that although this or even our sanitation. by persons who are themselves disease is still more or less a If the latter is responsible. victims of that disease, but children's disease here, such is /Continued on Following Page) (Continued from Preceding Page) tially infectious, the health of- one could propose the hy- ficer is at a serious disadvan- pothesis that modern hygienic tage. The fact that 80 many methods might have reached people who have no recogniz- that point at which infants able symptoms may have very and very young children are mild infections means that being pretty well protected many potentially infectious in- from exposure to this virus, dividuals are at. large in a but has not yet reached a community during an epi- point which protects them demic, and there is no means later-that is, during childhood of labeling them as such or or adolescence; and so their controlling their activities. "attack of poliomyelitis" has The hope for measures then been postponed, not elimi- to eliminate the virus from a nated. These hypotheses are community and thus rid our- mentioned merely to show selves of this disease by such that much remains to be means is not good. learned about the principles involved in, as well as the A PPARENTLY what is techniques for, preventing this disease needed most in the struggle to /A more practical question is prevent poliomyelitis is some means of bolstering the immu- whither this disease is spread nity of children (and adults) by agents other than infected to enable them to resist in- persons-food, water, insects, fection induced by periodic ex- for example-as is the case, posure to the virus. That is, for instance, with streptococ- we would combat poliomyelitis cal diseases and typhoid fever. as we now combat smallpox, If such were the case with poliomyelitis these "inter- diphtheria and whooping cough-by vaccination. mediate" agents might be con- trolled by "sanitary" meas- Since no vaccine for polio- ures. They do not loom large myelitis is available, our pre- dictions can go no further, but in the picture at present. it has long been obvious to T students of this disease that HAT poliomyelitis virus it is desirable to discover has been found on food (pos- strains of virus which, when sibly contaminated by flies) inoculated into man, would and in flies during an epi- cause a mild "disease" only, demic there is no doubt. But and at the same time serve to there is no evidence that flies immunize against poliomyeli- are an essential link in the tis. This would be similar to chain, as are mosquitos in the the way that "cowpox" virus, transmission of malaria, in now known as vaccine virus, which they carry a parasite; confers immunity on the in- or in yellow fever, in which dividual vaccinated against they carry a virus. Further- smallpox. more, in certain situations The development of such a where poliomyelitis has oc- vaccine is the great quest on curred it is difficult to imag- which the energy of many re- ine how flies could possibly search laboratories is now have played much or any part being expended and to which in the spread. the resources of great institu- For the present the control tions and foundations in a measures devised to protect number of different countries, communities against polio- such as our own National myelitis are therefore based Foundation for Infantile Pa- essentially on our knowledge ralysis, are being turned. The that people (usually children) path is difficult and danger- in the early stages of recog- ous, and it would seem highly nizable or suspected poliomye. unlikely that an effective vac- litis are infectious, and that cine will be reached by inves- the situation in the family. tigators working on mice and the home and the community monkeys alone. For the real should be handled accordingly. experiment will come when When it comes to quarantin- the new vaccines are tried on ing individuals who are poten- man. A process in the efforts to isolate the poliomyelitis virus. Withdrawal/Redaction Sheet (George Bush Library) Document No. Subject/Title of Document Date Restriction Class. and Type 03. Notes Handwritten notes, Re: President's AIDS speech; personal n.d. (b)(6) information redacted. (1 pp.) Collection: [Original OA/ID 06854] Record Group: Bush Presidential Records Office: Speechwriting, White House Office of Series: Speech File, Backup Subseries: Chronological Files WHORM Cat.: File Location: National Coalition on AIDS 3/29/90 [2] Date Closed: 10/15/2004 OA/ID Number: 13710-010 FOIA/SYS Case #: S Appeal Case #: Re-review Case #: 2004-2265-S Appeal Disposition: P-2/P-5 Review Case #: Disposition Date: AR Case #: MR Case #: AR Disposition: MR Disposition: AR Disposition Date: MR Disposition Date: RESTRICTION CODES Presidential Records Act - [44 U.S.C. 2204(a)] Freedom of Information Act - [5 U.S.C. 552(b)] P-1 National Security Classified Information [(a)(1) of the PRA] (b)(1) National security classified information [(b)(1) of the FOIA] P-2 Relating to the appointment to Federal office [(a)(2) of the PRA] (b)(2) Release would disclose internal personnel rules and practices of an P-3 Release would violate a Federal statute [(a)(3) of the PRA] agency [(b)(2) of the FOIA] P-4 Release would disclose trade secrets or confidential commercial or (b)(3) Release would violate a Federal statute [(b)(3) of the FOIA] financial information [(a)(4) of the PRA] (b)(4) Release would disclose trade secrets or confidential or financial P-5 Release would disclose confidential advice between the President information [(b)(4) of the FOIA] and his advisors, or between such advisors [a)(5) of the PRA] (b)(6) Release would constitute a clearly unwarranted invasion of P-6 Release would constitute a clearly unwarranted invasion of personal privacy [(b)(6) of the FOIA] personal privacy [(a)(6) of the PRA] (b)(7) Release would disclose information compiled for law enforcement purposes [(b)(7) of the FOIA] C. Closed in accordance with restrictions contained in donor's deed of (b)(8) Release would disclose information concerning the regulation of gift. financial institutions [(b)(8) of the FOIA] (b)(9) Release would disclose geological or geophysical information PRM. Removed as a personal record misfile. P-6, (b)(6) Belinda Mason - talk about am. w/Disabilitis act AIDS is a not'l. disaster Epidemic is not over enough will net worse We are rich & compassionate to care for all people with diseases. Compassion doesn't cost anything. need nat'l leadership doesn't know the President AIDS community wants the issue treated Call before using her as an example got aIDS about 3 years ago with a blood transfusion during the birth of her baby ge Bush, 1989 Administration of G loration Two decades ago, the men of Apollo 11 United States Senate and 5 are appointed Letter to the Cl began our journey into the universe, taking by the House of Representatives. and House Com with them our heartfelt prayers and our Belinda Ann Mason, of Indiana. This is a new Appropriations highest hopes. They opened a door that can position. Since 1988 Ms. Mason has been presi- Communication tes never be closed and, in so doing, changed dent and a member of the board of directors Interdiction forever the course of human history. As we for the National Association of People with July 20, 1989 continue to follow the steps of those brave AIDS (NAPWA) in Washington, DC. Since 1988 she has served as an AIDS educator and con- Dear pioneers, wherever we travel, we will, like sultant, traveling throughout the country them, have come in peace for all mankind. The enclosed rt !0, 1969, speaking to educational institutions, interest ne Moon, Now, Therefore, I, George Bush, Presi- porting requirem groups, health care professionals, and legisla- f the uni- the FY 1989 Nat dent of the United States of America, by tors. tion Act. at "giant virtue of the authority vested in me by the David E. Rogers, of New Jersey. This is a new a million The report foc Constitution and laws of the United States, position. Since 1986 Dr. Rogers has served as triumph tions support for do hereby proclaim July 20, 1989, as Space the Walsh McDermott university professor of responsibilities foi urage-it Exploration Day. I call upon the people of medicine at Cornell University Medical Col- American cations network; the United States to observe this day with lege. Prior to this, he was president of the appropriate programs, ceremonies, and ac- Robert Wood Johnson Foundation in Princeton, the funding appro teroperable intera ive been tivities. NJ. frastructure to sup nination, In Witness Whereof, I have hereunto set Richard Cheney, Secretary of the Department of forts; highlights th nericans, my hand this 20th day of July, in the year of Defense. cations network onstrated our Lord nineteen hundred and eighty- Edward Dericinski, Secretary of Veterans Af- comprised of sev Like the nine, and of the Independence of the fairs. systems and that e space United States of America the two hundred Louis Sullivan, Secretary of Health and Human subsystems serve ve since and fourteenth. Services. and are not nece! mpelling interdiction suppo y of the George Bush A similar letter the ex- man, House Comr of men [Filed with the Office of the Federal Regis- and the Chairmen al Aero- ter, 11:20 a.m., July 21, 1989] Statement on the Crash of a United Committees on Ap on, the merican Airlines Jetliner in Sioux City, Iowa Sincerely, institu- July 20, 1989 qualities Appointment of Five Members of the ay. Barbara and I extend our deepest sympa- Note: Identical le venture National Commission on Acquired thy to the families and friends of the vic- Nunn, chairman 0 out our Immune Deficiency Syndrome tims of Flight 232. Our hearts-indeed, the ices Committee; R miverse July 20, 1989 hearts of all Americans-go out to them in the Senate Appro ave en- their time of sorrow. Aspin, chairman c fic pur- The President today announced his inten- ices Committee; demon- tion to appoint the following individuals to I am sure I speak for many when I com- chairman of the hen we be members of the National Commission on mend the extraordinary efforts of the air- Committee. work in Acquired Immune Deficiency Syndrome. port personnel, rescue teams, National The National Commission on Acquired Guardsmen, and local citizens who rushed indreds Immune Deficiency Syndrome was estab- to the crash scene to offer aid. The compas- e have lished by Public Law No. 100-607 on No- sion and generosity demonstrated by the ng dec- vember 4, 1988. The Commission has 15 entire Sioux City community in the wake of Remarks at a Cei I, trans- members, 5 of which are appointed by the this catastrophe has been overwhelming. Commemorating end of President. Of these 5 appointed members, 3 July 21, 1989 Today we pray for the passengers killed -which are the Secretary of Health and Human on Flight 232. Let us also ask God to bless Thank you all f ith our Services, the Secretary of Veterans Affairs, their loved ones and those survivors who White House. And pportu- and the Secretary of Defense; and the other remain hospitalized. May they find strength to the White Hou nd pro- 2 are chosen from the general public. The and comfort in their faith and in the love of Captive Nations W of the members serve for the life of the Commis- family and friends. but blessed by hop sion. Five members are appointed by the Administration of George Bush, 1989 / Dec. 22 1928, in New York City. Mr. Lambert society that they voted for and that they so served in the U.S. Army, 1953-1955. He is rightfully deserve. married, has three children, and resides in In these last days before Christmas, I did New York. want to stop by here and salute what you are doing in biomedical research-the best, the very finest, all of you. For here, too, in your way you are standing for decency. Remarks to the AIDS Research Staff at You're helping to improve the health of the National Institutes of Health in millions of Americans. And even more, like Bethesda, Maryland those soldiers in Panama, those heroes, you're giving the greatest gift imaginable: December 22, 1989 the gift of life. And nowhere is this gift more evident than in your work to combat Thank you all very much. I'm so very AIDS. And it's that which I'd briefly like to proud to be accompanied here and intro- talk about today. For only together can we duced here by Lou Sullivan. Barbara is, too. wage all-out war against this terrible killer. A little historical Trivial Pursuit: Bar used to be on the Morehouse School of Medicine Two years ago in this very building, I met a person with AIDS who spoke of his pro- Board, working for a slave driver named longed suffering. And I've just come from Lou Sullivan. [Laughter] And so, it's fitting two more meetings-one with a patients' that they be sitting side by side. support group and the other, a family sup- To Under Secretary Horner, if she is port group-and both reminded me of the here, and Dr. Mason and Dr. Raub, Dr. need for compassion and understanding. Fauci, Dr. Broder and Dr. Decker and Dr. And by that, I mean the compassion that Rall and Dr. Bick and Dr. Goodwin- moves us to care for all those infected with [laughter]-Dr. Lenfant, Dr. Alexander, and the HIV, men and women, adults and chil- whoever is left out, all the rest of you: I am dren. And we must help them. And you, delighted, I mean it, really pleased, and so is you above all, are doing just exactly that. Barbara, to be here. And I want you to know, I am with you and This morning, let me just say a word extraordinarily grateful for what you are about another area before I just make a few doing. And by understanding, I mean edu- comments on your work, your wonderful cating, educating Americans who don't work. I am sure that your hearts and minds want to help, don't want to become in- are with our kids, our brave soldiers in volved because of a misplaced fear. They're Panama, so let me just say a quick word afraid of holding an AIDS patient because about that. As I said yesterday, all human they're frightened of getting AIDS. Barbara life is precious. We're all children of a and I want to say, and we hope we can loving God, and we sorrow at the casualties continue to demonstrate this, they are in Panama. But we know that nothing is wrong. They're simply uninformed. They n- more crucial to peace on Earth than free- are wrong about that. e dom and democracy. And that's what our A few minutes ago, we were in a room n- American soldiers are achieving: freedom full of kids with AIDS, and you could just e and human liberty for those who have en- feel the courage and character of the doc- ed dured brutal tyranny and brutal oppression. tors and the nurses and the parents and the And this weekend, Americans will begin counselors. And being with them, I thought a our traditional holiday celebration. And it is of how there is no reason to fear for your tt a time of rest and reflection and, most of health, just their health. And I want to he all, of family. And while America stops to thank those who are not afraid, especially of catch its breath from the dramatic events of foster parents who have opened their in 1989, I assure you that through these holi- homes and their hearts, and those of you days we will not forget our brave soldiers here today who do so much for so many. ni- down there and their families. We will con- And my good friend, Dr. Lou Sullivan, aw tinue to do what is necessary to help the our Secretary-it's appropriate that he be 14, people of Panama achieve the democratic here with us today. He knows about com- 1987 Dec. 22 / Administration of George Bush, 1989 passion and understanding. And so do other And God bless the United States of Amer- December 16 great men and women of science and medi- ica. And Merry Christmas to all. Thank you Jack L. Powell, of Sal cine. I think of our Assistant Secretary, Dr. very, very much. ganizes the annual James Mason, or Dr. William Raub, the his home town. B Acting Director of NIH, who greeted us Note: The President spoke at 12:34 p.m. in House drive has rais here; Doctor Fauci, who is still embar- the Clinical Center. In his remarks, he re- clothing for impove rassed, I think, that I singled him out in the Contributors have ferred to Secretary Louis W. Sullivan, last year as a hero, but he is; and Dr. Sam school students to t Under Secretary Constance Horner, Assist- Broder and Robert Gallo, Dr. Antonia No- pioneered the shop ant Secretary James O. Mason, and Dr. vello, the Surgeon-General-designate. Each This technique has of these dedicated scientists preaches com- Frederick K. Goodwin, Administrator of the organizations, inch passion and understanding, as do others in- Alcohol, Drug Abuse, and Mental Health America, who colle volved in treatment and research activities Administration, of the Department of in their 1989 food C on AIDS at the NIH Clinical Center, from Health and Human Services. The President December 18 doctors and nurses to chaplains and social also referred to the following National In- stitutes of Health staff members: Dr. Wil- Aja Dyani Henderso workers, from teachers to dietitians. For ex- Henderson, 15, saw ample, the clinical pathology staff, the diag- liam F. Raub, Acting Director; Dr. Anthony hood. Children wh nostic radiology staff, the nuclear medicine Fauci, Associate Director for AIDS Re- get to the public ] staff-you are attacking the scourge of search; Dr. Samuel Broder, Director, Na- means of transpor AIDS; and so are the laboratory scientists tional Cancer Institute; Dr. John Decker, brary in her own engaged primarily in AIDS-related basic re- Director of the Warren Grant Magnuson in her community search, all of the dedicated employees Clinical Center; Dr. Joseph E. Rall, Deputy own collection, sh throughout all the institutions here. Director for Intramural Research; Dr. Ka- books. Unlike the You know, there is a lot of talk about therine L. Bick, Deputy Director for Extra- open through the AIDS today. And I hear those who say we also volunteers in mural Research and Training; Dr. Claude have far to go. And, yes, they're right. But I gram targeted at il Lenfant, Director, National Heart, Lung would also add: Look how far we've come. and Blood Institute; Robert C. Gallo, Chief, December 19 And look at the advances in vaccine devel- Laboratory of Tumor Cell Biology, National GlenCastle Project, opment and early therapeutic intervention. Cancer Institute; and Dr. Duane Alexander, is transforming a Look at the recently reported success of a Director, National Institute of Child Health cost housing for h vaccine in animals or clinical studies which and Human Development. Secretary Sullivan to 1929, the Atla show how AZT can retard the disease in is a former president of the Morehouse most infamous pr infected individuals. Look at the treatment School of Medicine. Prior to his remarks, the ing it has been a to prevent the onset of PCP, the pneumo- President attended an AIDS family support addicts. But next nia that infects large numbers of AIDS pa- group meeting. Following his remarks, the reopen as a com tients and often, regrettably, leads to death. will include 67 a President and Mrs. Bush flew to Camp Where did these advances stem from? lies, nonprofit fo David, MD, for the Christmas holiday. care center, a j They're rooted in the biomedical research chapel. conducted and supported by NIH. And they show the value of your commitment, and I December 20 commend that commitment. They stem Eugene Lang, of N from your work which makes America Points of Light Recognition Program the founder of th proud. tion, which enco Too often, we speak of compassion and The President named the following individ- school by offerin understanding only in this time of year, the port, and guara Christmas season. You embody it, and you uals and institutions as exemplars of his education. In 198 live it all year round. And too often we commitment to making community service by offering to pe forget the true message of this time of year. central to the life and work of every Ameri- group of Harler It's that justice and kindness can indeed can. The daily recognition program is in- stay in school. foster good will toward all. tended as a national tribute of the highest Dream" Found order to every single American who makes a chapters in 32 ci You know that message. You live that difference in the life of someone in need. Lang giving bot message. And for that, I thank you. And I over 9,000 kids want to wish you and your families a warm volunteers in e: and happy holiday season. God bless you The President extends his appreciation to develop relation and those you are working so hard to save. the following: gram. 1988 A Private Sector Leadership Response to the Challenges of AIDS NATIONAL LEADERSHIP COALITION ON AIDS National Leadership Coalition on AIDS Suite 202 1150 17th Street, N.W. Washington, D.C. 20036 202/429-0930 GCIU C439 T.M. (Terry) Mulready Pacific Bell THE NATIONAL Emilio R. Nicolas, Jr. LEADERSHIP KMEX-TV, Los Angeles COALITION Beny J. Primm, Jr., M.D. Addiction Research Treatment Corporation ON AIDS Mervyn F. Silverman, M.D. American Foundation for AIDS Research A National Private Sector Response The Rt. Rev. William E. Swing Episcopal Diocese of California to the HIV Epidemic Larry H. Williford Allstate Insurance Company A IDS, Acquired Immune Deficiency Syndrome, is the most complex health problem our nation faces today. An insidious killer, the disease is spreading SO rapidly that few will be spared its devastating impact, either personally or indirectly. The only hope of limiting its fatal spread and dealing humanely with its tragic consequences is for each of us to become actively involved. It is none too early. The rapidly-mounting numbers tell the chilling story all too well. According to the Centers for Disease Control, 68,220 cases of AIDS had been reported in the U.S. by the middle of 1988. Of those individuals, 38,541 have died. The outlook is also bleak. The U.S. Public Health Service estimates that by the year 1991, 285,000 will have AIDS, of whom 195,000 will have died. The global figures are shocking. As of June 30, 1988, 100,410 people are known to have contracted AIDS worldwide, and approximately half have already succumbed. The World Health Organization documents over 130 countries with cases of AIDS. 12 1 THE NATIONAL BOARD OF DIRECTORS LEADERSHIP COALITION: Officers John R. Taylor Chairman & CEO (Ret.), The Principal Financial Group, Chair A Catalyst for Action J. Richard Munro As the challenges of the HIV epidemic Chairman & CEO, Time Warner Inc., Vice Chair steadily mount, there is also a growing David N. Sundwall, M.D. recognition that no single segment of our Vice President, AmHS Institute, Vice Chair society can marshal the resources required to Karen Ignagni respond to the fears and help individuals and Assoc. Dir., Occupational Safety and Environmental Affairs, AFL-CIO, Secretary society cope with the burdens of AIDS. Michael Pollard That is why the National Leadership Partner, Michaels & Wishner, P.C., Treasurer Coalition on AIDS was established in May B.J. Stiles 1987. Its goal is to bring together the President collective resources of the private sector- Gwynn C. Akin, Ph.D. corporate, non-profit and charitable-to Syntex Corporation respond to the AIDS crisis. Lewellys F. Barker, M.D. Composed of major corporations, labor, American Red Cross trade and professional associations, and key Nora Kizer Bell, Ph.D. civic, voluntary, religious, gay and ethnic University of South Carolina groups, the National Leadership Coalition Erline Belton reflects the diversity of American society. Digital Equipment Corporation Although they may differ ideologically, the Edward N. Brandt, Jr., M.D., Ph.D. College of Medicine, Oklahoma University, Health Sciences Leadership Coalition's diverse members share Center a common commitment to helping people Sharon Canner with AIDS and their loved ones, and to National Association of Manufacturers preventing its further spread. Glenn E. Haughie, M.D. International Business Machines Corp. William R. Hendee, Ph.D. American Medical Association Stephen E. Herbits Joseph E. Seagram & Sons, Inc. Stanley G. Karson Center for Corporate Public Involvement Larry Kessler AIDS Action Committee of Massachusetts Bryan Lawton, Ph.D. Wells Fargo Bank Sam S. McKeel The Sun-Times Company Stephen T. Moskey Aetna Life & Casualty 11 2 The National Assembly of National Voluntary Health & Social THE NATIONAL Welfare Organizations, Inc. National Association of People with AIDS LEADERSHIP National Coalition of Hispanic Health and Human Services Organizations COALITION: National Council of La Raza National Education Association The National Foundation for Infectious Diseases What We're Doing To Help America National Gay & Lesbian Task Force National Health Council Face the AIDS Challenge The National Hemophilia Foundation While no cure or vaccine for AIDS is in National Hospice Organization 1 The National Kidney Foundation sight, the Leadership Coalition's members are National Minority AIDS Council working with other key executives and New York University (School of Education, Health, Nursing decision-makers to combat the epidemic. We and Arts Professions) The Salvation Army are supporting improved education and The Stop AIDS Resource Center services and promoting the policies and United Church Board for Homeland Ministries United Way of America strategies required to cope with the awesome Volunteers of America challenges of AIDS. The Coalition represents business and labor Local and Regional Associations, Voluntary, Religious, in responding to AIDS, and encourages and Educational Organizations national private sector organizations to AID Atlanta collaborate in responding to the epidemic. AIDS Foundation of Chicago AIDS Resource Center The Coalition bridges the gap between groups Boston AIDS Consortium recently emerging on the AIDS policy scene California Medical Association and those already established as experts. The Carl Vogel Foundation Citizens Commission on AIDS for the New York City-Northern The National Leadership Coalition on AIDS New Jersey Region is not a lobbying organization. Rather, it has Concern for Dying Greater Detroit Area Health Council these overall objectives. Howard Brown Memorial Clinic Instituto Familiar de la Raza-Latino AIDS Project 1. Improving understanding Mothers of AIDS Patients Philadelphia AIDS Task Force This involves supporting informational Phoenix Shanti Group, Inc. campaigns about AIDS, highlighting emerging Planned Parenthood of New York City, Inc. needs stemming from the disease and its San Francisco AIDS Foundation Washington Metropolitan Area Business Leadership Taskforce impact, and promoting balanced and informed on AIDS consideration of public policies involving Whitman-Walker Clinic AIDS. Grantmaking Organizations 2. Encouraging cooperative efforts American Foundation for AIDS Research Design Industries Foundation for AIDS This includes stimulating private sector Funders Concerned About AIDS involvement, improving business and labor The Hunt Alternatives Fund Pettus-Crowe Foundation response to AIDS, enhancing public/private sector collaboration, promoting American 10 3 traditions of justice, fairness and compassion, Pfizer, Inc. and sharing resources with and offering other Pharmaceutical Manufacturers Association Philip Morris Inc. assistance to national and international Playboy Enterprises, Inc. organizations focusing on AIDS. Polaroid Corporation The Principal Financial Group The Procter & Gamble Company A Record of Accomplishment to Date The Prudential Insurance Company of America Public Relations Society of America In the short time since its founding, the Security Life of Denver National Leadership Coalition has moved Security Pacific Corporation 1 Service Employees International Union swiftly to accomplish these objectives. These Southern California Edison Company activities include: Southern New England Telephone Spelling Entertainment, Inc. Co-sponsored a conference with Allstate Syntex (U.S.A.) Inc. Time Warner Inc. Insurance Company entitled "AIDS: Transamerica Occidental Life Insurance Co. Corporate America Responds." The US WEST, Inc. Union Carbide landmark conference was attended by more United Auto Workers - General Motors than 350 senior executives and produced an Wells Fargo Bank influential report that is helping executives address the implications of AIDS on their National Voluntary, Religious, and Educational organizations and businesses. Organizations and Associations Academy for Educational Development Produced a brochure addressing AIDS in AIDS Action Council AIDSFilms, Inc. the workplace. It has been distributed to AmHS Institute 230,000 workers by 800 corporations and American Academy of Family Physicians businesses, including Joseph E. Seagram & American College of Cardiology American College Health Association Sons, The Equitable Life Insurance Society, American Hospital Association and Pacific Northwest Bell. American Institutes for Research American Lung Association Collaborated with Fortune magazine in American Medical Association launching a groundbreaking survey that American Nurses Association American Pharmaceutical Association analyzed CEO attitudes and actions in American Psychological Association response to AIDS, and developed several American Public Health Association AIDS presentations for the annual Fortune American Red Cross Corporate Communications Seminar. American Society of Hospital Pharmacists Association of American Medical Colleges Helped to form regional and industry task The Association of Junior Leagues Catholic Health Association forces on AIDS. Center for Community Change Center for Population Options Co-sponsored with PBS a videoconference Children's Defense Fund in May, 1988 on "AIDS: A Matter of The Episcopal Church Center Corporate Policy." This closed-circuit, four- Gay Men's Health Crisis Health and Welfare Ministries, General Board of Global hour training conference involved over Ministries, United Methodist Church 3,000 managers from 140 American cities Healthcare Financial Management Association and focused on the development of Hospice Foundation Human Interaction Research Institute corporate policies towards AIDS by business Human Rights Campaign Fund executives. National AIDS Network 4 9 ROSTER OF MEMBERS Assisted the Presidential Commission on the HIV Epidemic in selecting topics, obtaining Business and Labor and preparing witnesses, developing Abbott Laboratories materials for its report, and seeking support Abt Associates for the Commission's work. Aetna Life & Casualty Allstate Insurance Company American Brands, Inc. Presented briefings and training seminars at American Council of Life Insurance more than 25 local/regional/industry American Federation of Labor and Congress of Industrial gatherings that focused on corporate and Organizations American Federation of State, County & Municipal Employees business concerns about AIDS policies. American Federation of Teachers Coordinated briefings and seminars for American Telephone & Telegraph Apple Computer, Inc. grantmakers and grantseekers interested in Associated Madison Companies, Inc. filling gaps. Bellcore Blue Cross Blue Shield Association Boeing Commercial Airplane Company Education as Our Primary Weapon Bristol-Myers Squibb Company Burroughs Wellcome Company Why We Need Your Help CBS, Inc. CIGNA Corporation Our primary weapon against further Chevron, U.S.A., Inc. transmission of the HIV virus is eduation. Ciba-Geigy Every American should understand that AIDS Digital Equipment Corporation Employee Assistance Professionals Association, Inc. is preventable and how each person can The Equitable Life Assurance Society protect him or herself. Foote, Cone & Belding Yet this education needs to be undertaken General Electric General Mills, Inc. on a scale that no single entity or sector can Group Health Association of America hope to accomplish on its own. The same is Health Industry Manufacturers Association Health Insurance Association of America true for other actions urgently needed today. Hoffmann-La Roche Inc. Only a unified effort has any chance of success Institute for Disease Prevention in the Workplace to counter this true epidemic. International Business Machines Corp. Johnson & Johnson The National Leadership Coalition on AIDS Joseph E. Seagram & Sons, Inc. is leading a collaborative effort, and we urge Levi Strauss & Co. you to join our ranks. The larger our Levine, Huntley, Schmidt & Beaver Lincoln National Corporation membership, the more effective we will be. Loews Hotels Corporation Your active participation can make a valuable Marshall Field & Company contribution. Maytag Corporation Mead Corporation We are counting on your support-on Mercantile and General Reinsurance Company behalf of the hundreds of thousands who will Merck & Co. be afflicted-and on behalf of all of us who Meredith Corporation Metropolitan Life Insurance Co. will be affected in one way or another. Mobil Oil Corporation Motorola, Inc. NCR Corporation National Association of Chain Drug Stores National Association of Home Builders National Association of Manufacturers Northwestern Mutual Life Insurance Company Ogilvy & Mather Pacific Bell 8 5 Membership Benefits NATIONAL The National Leadership Coalition on AIDS LEADERSHIP offers members a key role in joining forces COALITION to limit the impact of a disease that would otherwise go unchecked. ON AIDS Specific membership benefits include: Membership Enrollment Form Immediate access to the only national Yes, I want to become a member of the network of corporate and non-profit National Leadership Coalition on AIDS. Please organizations actively concerned with AIDS enroll me as a: issues. Membership Categories Annual Dues A bi-monthly resource packet of timely Business/Labor $1,000 materials that describes what the Coalition, its members, and other groups are doing to National Voluntary combat AIDS. Included are samples of the Organization Member 500 latest resources available to fight this battle. Local Voluntary Organization The opportunity to play a leadership role in Member 100 the war against AIDS. Grantmaking Organization Please complete the membership form and Member 1,000 join the National Leadership Coalition on AIDS Associate Member 100 today! (Individuals who wish to support the purposes of the National Leadership Coalition on AIDS) Name Title (if Corporate/Organization Member) Company/Organization (if appropriate) Address City State Zip Phone No. Please return this form to: B.J. Stiles President National Leadership Coalition on AIDS 1150 17th Street, N.W. Suite 202 Washington, D.C. 20036 (202) 429-0930 6 7 Business and Labor speak out onAIDS NATIONAL LEADERSHIP COALITION ON AIDS 202/429-0930 Washington, D.C. 20036 1150 17th Street, N.W. Suite 202 National Leadership Coalition on AIDS "The AIDS epidemic is a rip in the fabric of our society. Left unmended, it will unravel " Contents FOREWORD 4 Edward N. Brandt, Jr., M.D., Ph.D., Chair, National Leadership Coalition on AIDS A CORPORATE OVERVIEW 7 Robert D. Haas, Chairman & CEO, Levi Strauss & Company AIDS: A CHALLENGE TO BUSINESS 17 Albert Bowers, Ph.D., Chairman & CEO, Syntex Corporation 18 Anthony A. Herrmann, M.D., Vice President, Johnson & Johnson 18 Richard J. Haayen, Chairman & CEO, Allstate Insurance Company 19 Ann McLaughlin, former Secretary, Department of Labor 19 Andrew V. Smith, President, Pacific Northwest Bell 20 Bryan Lawton, Ph.D., Vice President & Director, Employee Assistance Services, Wells Fargo Bank 20 Stanley G. Karson, Director, Center for Corporate Public Involvement 21 Admiral James D. Watkins (Ret.), Secretary, Department of Energy and former Chairman, Presidential Commission on the Human Immunodeficiency Virus Epidemic 21 Ronald B. Eisenhauer, Vice President, Sales, U.S. Central Area, Digital Equipment Corporation 22 Peter W. Bertschmann, Vice President, Human Resources, New England Telephone 22 Robert V. Van Fossan, Chairman & CEO, Mutual Benefit Life Insurance Company 23 Robert A. Beck, Chairman Emeritus, Prudential Insurance Company of America 23 Sandra S. Person, Executive Director, Houston Area Health Care Coalition AIDS: A NEED FOR CIVIC RESPONSIBILITY 24 John J. Sweeney, International President, Service Employees International Union 25 Lawrence H. Williford, Senior Vice President, Allstate Insurance Company 25 David R. Carpenter, Chairman & CEO, Transamerica Occidental Life Companies 26 Herbert E. Lister, Chairman, Allstate Insurance Company 26 Charles E. McKittrick, Jr., Vice President, Governmental Programs, International Business Machines 27 P. Roy Vagelos, M.D., Chairman & CEO, Merck & Company 2 27 Richard S. Schweiker, President, American Council of Life Insurance 28 John B. Carter, President & CEO, Equitable Life Assurance Company 28 Jordan A. Barab, Occupational Safety & Health Coordinator, American Federation of State, County and Municipal Employees 29 Carl J. Schramm, President, Health Insurance Association of America 30 Margaret M. Seminario, Associate Director, Department of Occupational Health, Safety and Social Security, AFL-CIO 31 William F. Sinclair, President, Greater Washington Board of Trade 31 Al Shanker, President, American Federation of Teachers 32 Gwynn C. Akin, Ph.D., Director of Health Policy, Syntex Corporation AIDS: A CALL FOR LEADERSHIP 33 Admiral James D. Watkins (Ret.), Secretary, Department of Energy and former Chairman, Presidential Commission on the Human Immunodeficiency Virus Epidemic 34 John J. Creedon, President & CEO, Metropolitan Life Insurance Company 34 Benneville N. Strohecker, President, Harbor Sweets 35 Sam S. McKeel, Publisher & Chairman, Philadelphia Newspapers, Inc. 35 Theodore Cooper, M.D., Ph.D., Chairman & CEO, The Upjohn Company and Chair, Committee for the Oversight of AIDS Activities, Institute of Medicine 36 Mary Hatwood Futrell, President, National Education Association 36 Terry M. Mulready, Vice President-External Affairs/Corporate Communications, Pacific Bell 37 Paul A. Ross, Ed.D., Manager, AIDS Program Office, Digital Equipment Corporation 37 William K. Borwegen, Director, Occupational Health & Safety, Service Employees International Union 38 Arthur H. White, President & CEO, WSY Consulting Group, Inc. 39 James W. Curran, M.D., M.P.H., Director, AIDS Program, Centers for Disease Control 40 Sanford Cloud, Jr., Vice President, Corporate Public Involvement, AEtna Life & Casualty Foundation 40 Otis R. Bowen, M.D., former Secretary, Department of Health and Human Services 3 Edward N. Brandt, Jr., M.D., Ph.D Chair, National Leadership Coalition on AIDS Foreword AIDS is one of the most serious health problems facing America today. Measured in terms of actual and potential costs, and in human suffering, AIDS challenges every sector of society. It calls for bold, innova- tive responses. It demands leadership as the na- tion mobilizes its resources. AIDS presents opportunities as well as challenges, especially for business and labor. It may challenge our ability to do business. But we can meet this challenge by actively dealing with AIDS as a workplace issue. AIDS also offers US an opportunity to fulfill an im- portant civic responsibility. We can serve the pub- lic interest by sponsoring education, mobilizing communities, supporting AIDS services and pro- grams, and actively contributing to the nation's response. Finally, AIDS is a call for leadership in a time of crisis. AIDS is not a problem of government. It is a problem of society. Everyone, including business and labor, must be- come involved in finding solutions. Local commu- nities need help as they mobilize their resources to fight AIDS. Above all, they need leadership. Business and labor can provide this leadership, just as we have at other critical times in our na- tion's history. Many com- panies and labor unions have courageously spo- ken out on AIDS. The speech by Robert D. Haas, Chairman & CEO of Levi Strauss & Company, de- livered in Boston on March 16 in conjunction with the presentation of the George S. Dively Award for Corporate Public Initiative, exemplifies the highly visible leadership role of one outstanding corporate executive. Other executives and labor leaders cited in this booklet also have taken forceful positions. Some companies remain on the sidelines. They are convinced that because they and their communities are not yet directly experiencing the impact of the epidemic, there is no need to become involved. The AIDS epidemic has just begun, however. The full impact is still in front of us. The costs to business and la- bor, as well as to society, could be high. But in fact, tomorrow's costs will depend in large part upon what business and labor do today. Edward N. 5 AIDS: Meeting Tomorrow's Challenge ROBERT D. HAAS, CHAIRMAN & CEO, LEVI STRAUSS & COMPANY Delivered at the presentation of The George S. Dively Award For Corporate Public Initiative Harvard University March 16, 1989 6 A Corporate Overview It is a great honor for me to address this audience of influential business, academic and community leaders. We are joined together today by our concern about AIDS, a subject of critical importance. ften when we talk about the HIV epidemic, we get caught up in the technical language of medicine or the impersonal realm of statistics. I think it's important to focus on the human dimension of the epidemic. very day in this country, and around the world, an increasing number of people find themselves locked in the battle with this grave and relatively new illness. They wage this fight with courage. Sometimes they are alone. Sometimes they have the love and support of family, friends and community. When I think about AIDS, I see people's faces-a dear friend, employ- ees with whom I worked closely. You may recall faces of people you know who have been stricken by this re- lentless disease. Please remember these faces as I speak. By recalling them, what I am going to say will become more personal for each of us. AIDS reaches well beyond those we know. Its deadly embrace ensnares men, women and children of all ages, colors and nationalities; in San Francisco, in Boston and around the globe. For every individual who is diagnosed, there's an immediate circle of family and friends who are affected. Many of you know and deal directly with the consequences of AIDS. While scientists struggle to find a cure, the grim toll keeps rising. If we were to pause now and devote a second to each person with AIDS, our silent tribute would last nearly 24 hours. Two years ago, it would have been 10 hours. Five years from now, we would sit silently for five days. Even then we would be a little short. That's how fast the number of cases is rising. As of 1986, there were 37,000 cases. As of last year, 85,000 cases. The Public Health Service estimates that five years from now, there will be over 450,000 cases. 7 ublic health ex- perts say it won't be long-a mere three years-before American deaths from AIDS will reach roughly three times the number of deaths of all American service per- sonnel in the Vietnam War. To use another yardstick, in its first decade, AIDS deaths will exceed all lives lost during the polio epidemic that raged for 40 years. This rising tide of suffering and sorrow means a flood of new faces for us to remember in the future. Yet despite these horrifying statistics, our response to AIDS has been be- lated and tentative. Why? I believe our hesitancy is due to the fact that in this country, AIDS has had its greatest impact on people without a voice-people in groups that our society shuns or ignores: gay men, IV drug users and the poor. ur task, as a "kinder and gentler" nation, as compassionate people, is to make sure that those with AIDS are not isolated. Our task is to break the silence about AIDS, to give help to those in need, and to limit the further spread of this heartless epidemic. Today, I stand be- fore you representing a corporation headquartered in San Francisco. Our company has operations in large cities such as Knoxville, El Paso and Little Rock. We also have plants in smaller communities such as Valdosta, Georgia; Florence, Kentucky; and San Benito, Texas. We also have facilities in Canada, Europe, South Amer- ica and in the Pacific Rim countries. From our experi- ence in each of these communities, I can tell you that business cannot hide from this disease, no matter where it operates, whether in the U.S. or abroad, in small cities or large. Yet in this country, fewer than one company in 10 has an AIDS program or policy. The front lines of the AIDS war are advancing beyond cities like San Fran- cisco and New York. The Public Health Service says that within a few years, 80 percent of new HIV infec- tions will occur outside those areas where the infection currently is concentrated. 8 learly, one way or another, the HIV epidemic will have an impact on every business, large and small. Business leaders have a simple choice. We can wash our hands of the problem and be content with the decisions made by others, or we can roll up our sleeves and influence how this horrible epidemic is managed and mitigated. If you have not al- ready confronted the direct impact of HIV on your oper- ations, you soon will. What will happen in your com- pany when a person diagnosed with AIDS returns to work? Will other employees walk off the job? What will happen in your company when co-workers become hys- terical because they think the memos the department secretary has been handling might transmit AIDS? What will happen when a key member of your staff is work- ing on a critical assignment and becomes too ill to handle the task? None of us should underestimate the practical impact this epidemic will have on us, our customers, our suppliers and the way we conduct our everyday business. Additionally, business has a stake in this epidemic that goes well beyond its short-term effects on our operations and financial results. usiness cannot shoulder the burdens of government or family or indi- vidual responsibility. But neither can it shirk its own ob- ligation to address a social problem of this magnitude. It would be immoral and unconscionable for us to do so. Each of us must act to ensure that this does not occur. Six major areas need our attention and involvement. Each is crucial. Taken together, these issues represent an agenda for ac- tion that addresses the legitimate needs of business and our communities. Discrimination At the top of the list is discrimination. The Presidential Commission on the Human Immunodeficiency Virus Epidemic identified discrimination as the most significant obstacle to prog- ress against the epidemic. A few months ago, researchers 9 at the Harvard School of Public Health published a study. It showed just how great that obstacle is. Here are some of the findings: One in four Americans would refuse to work beside a person with the disease. Forty percent are opposed to having people with AIDS live in their neighborhoods. About half that group-17 percent-said people with AIDS should be banished to an island as lepers once were. Nearly a third of the people favored requiring any- one with a positive HIV blood test to be tattooed. These are views grounded in fear and ignorance. But they affect every re- gion of our country and every person fighting the virus. This kind of dis- crimination destroys housing and jobs for those afflicted. It blocks access to education, insurance and health care. It tears families apart. Ultimately, it undermines efforts to control the disease. So long as those infected or those at high risk fear losing their jobs or housing or insur- ance, they will be reluctant to come forward for testing, counseling and care. The sad thing is that from a health standpoint, there's no need to treat people with AIDS differently. As the Presidential Com- mission pointed out, in the vast majority of settings-the workplace, housing, schools-there's virtually no risk of contracting the disease from someone who has it. The Harvard re- port also suggested that if past epidemics are any guide, hostility and discrimination will increase as more people are personally threatened with the disease. This may in- deed be the case as the epidemic spreads rapidly-as it is-among IV drug users and urban low-income and mi- nority communities. What can business do to fight discrimination? It must start by weeding out discriminatory practices in its own operations. Dismissal of workers with AIDS must stop. Using pre-employ- ment testing to screen out HIV-infected persons must stop. From a purely practical standpoint, litigation costs arising from such policies can be ruinous. 10 ut more impor- tantly, business men and woman have a responsibility to their fellow human beings not to abandon or discard them when they most need our care and concern. Em- ployees with AIDS have the right to assume that their employers will fulfill their contract to provide medical care and disability benefits. usiness must also support federal legislation to shield HIV-infected people from discrimination in the private sector. Currently, they are protected by law only in the public sector. Education The second issue on my agenda is education. Fear and ignorance fuel dis- crimination. They also foster the spread of the epidemic. To press the attack on both fronts calls for greater use of a powerful and indispensable weapon-education about HIV. ducation pro- grams must be clear and direct so there's no confusion about how HIV is transmitted. Last month, the National Research Council reinforced the importance of clear, ex- plicit communication, customized for each specific group. Education programs must be pushed aggressively into every corner of society, from schools to the work- place. We especially must reach young people. The number of AIDS cases is doubling each year among those 13 to 21 years of age. A small study conducted at a shelter for run-away youths in New York City found that approximately 40 percent of the adolescents were infected with HIV. What can business do to fight fear and ignorance? Every company must es- tablish an education program for its workers and their families. Employers have one of the clearest and most direct channels of communication to enormous numbers of people. Experience bears out that workers' attitudes and reactions reflect those of management. Straight talk about AIDS can dispel myths that cause fear. ducating employ- ees also has a beneficial ripple effect-informed employ- ees share important concerns with family members, 11 friends and neighbors. Workers at Levi Strauss & Com- pany have responded well to AIDS information pre- sented in the workplace. We also know that having an education program in place before the problem arises can minimize disruption, maintain employee morale, and reduce incidence of discrimination against HIV- infected employees. In short, AIDS ed- uation works well in business. And it works for com- munities, too. San Francisco's experience has shown that education, when part of a broad-based community pre- vention strategy, can help stop the epidemic. In San Francisco, the annual rate of new infections among gay men is less than 1 percent. That compares to a rate of 10 to 25 percent just several years ago. This experience must be replicated across the country. But this cannot be done without leadership from the business and public health communities. As a community citizen, business can act as a catalyst to bring together the appropriate community organizations and leaders to start a commu- nity on the road to halting the epidemic. Once a forum is created, business can use its influence to ensure calm and considerate deliberation of the issues. I am pleased that business task forces on AIDS, such as the New England Corporate Consortium in Boston and the Metropolitan Business Task Force in Washington, D.C., are becoming active in a growing number of cities. I also want to rec- ognize the pioneering and excellent work being done by the National Leadership Coalition on AIDS to marshal the resources of both business and labor. Prevention third issue we must face is prevention. Here, our efforts are thwarted by uncertainties about the scope of the epidemic and our in- ability to identify people who require treatment and care. Widespread, confidential testing is essential if we are to stop the spread of AIDS. But it will happen only if it's voluntary, and only if the results are kept abso- lutely confidential. And it will never happen if we don't take the anti-discrimination measures I talked about first. 12 What can business do to limit the spread of AIDS? We should support voluntary, confidential testing and oppose efforts that threaten people's basic rights. This is important so people with HIV are identified and can get treatment and care. Recently, business in California did just this. Scores of major employers, including Levi Strauss & Company, stood up with doc- tors, nurses and others and said that violating confiden- tiality was bad medicine and bad public health policy. Our intervention helped defeat, by a two-to-one margin, a very damaging initiative to require mandatory report- ing of the names of those testing positive for HIV. Past epidemics have often pitted the civil liberties of indi- viduals against the rights of the public. This time, for- tunately, supporters of civil liberties and public health authorities are on the same side. dditionally, busi- ness should encourage new approaches for changing be- haviors which lead to HIV infection. We can educate our employees who can then educate their young people. Paying for Health Care Next on my agenda is the need to review the way we pay for health care in this country. The HIV epidemic has exposed and intensified the shortcomings of our current system. One in five AIDS patients has no insurance. Forty percent of all AIDS patients must rely on Medicaid-more than four times the proportion in the population at large. At one public hospital in Texas, fully 75 percent of its AIDS patients have no health insurance. This trend may be- come even more pronounced in the future. Increasingly, private health insurance carriers appear to be screening out HIV-infected persons, thus shifting the cost of their care to the public sector. Infected workers who are em- ployed by self-insured companies or companies with small group plans are being denied coverage. What can business do to address the payment issue? It must forcefully artic- ulate three messages. First, Medicaid's purse strings must 13 be loosened and its waiting period reduced. Second, the public sector must respond to this issue. Third, private health insurance must be bolstered. Health care must be accessible to everyone, including those with HIV. Business must work cooperatively with insurance com- panies to devise new cost-effective and humane solu- tions, such as volunteer home care. Then business must lead the way in testing these solutions and adopt- ing the best. Managing Health Care Services The next issue on my agenda is the need to deliver health care services in more efficient ways. HIV is becoming a chronic disease. People are living longer and need ongoing health care. What can business do to change the way health care services are managed? One promising innovation is case management. This technique involves assigning one person to manage all aspects of a patient's care-from dealing with social workers and arranging housing, food, home and hospice care to helping decide when a patient must be hospital- ized. Business can make a difference by taking the lead in bringing together the appropriate community re- sources to implement new models of care. We must challenge our benefits people. We must tell them to pull together and draw upon these resources so we can help our employees with AIDS rather than restrict them, and ourselves, to traditional formulas. San Francisco has developed a case-management model that provides a comprehensive, integrated system of community-based services for people with HIV. This model resulted from a creative collaboration between the private and public sectors. Other communities can cut the costs of health care by following this approach or by developing their own models. 14 Government HIV Policy The final issue on my agenda is the need to develop a government policy toward the HIV epidemic. Confused and cautious thinking and a lack of leadership in government only makes it more difficult to address AIDS-related issues in the workplace. What can business do to infuence government policy? Employers have a re- sponsibility to themselves and their employees to pro- mote enlightened approaches to the epidemic and to op- pose political measures based principally on fear. We should exert our influence at the local, state and national levels to assure rational government policies regarding the disease. These policies must be free from hysteria and political agendas. They must reflect scientific facts rather than extremist views. Whenever business leaders talk to government leaders, at whatever level, on whatever topics, we must raise the question of what's being done about AIDS. adical solutions may be needed in some instances. Consider the magni- tude of the nation's drug problem and the ineffectiveness of what we have done so far to solve it. Yet health ex- perts tell us our ability to control the course of the HIV epidemic depends greatly on our ability to control drug abuse. With lives being lost at an alarming rate, now is not the time for caution. AIDS isn't a conventional problem. So when we think about how to deal with it, we have to open ourselves to unconventional solutions. And that involves risk. Call for Leadership I call upon the business leaders of our nation-including those at the top of our biggest, most prestigious, most powerful corpo- rations-to join me in the fight to defeat this devastating disease. It's not someone else's fight. It's ours. We have the resources to do it. We have the ability to make a dif- ference. The question is, do we have the will? Can we break the inertia of "business as usual?" Can we put aside political differences? Are we willing to fight homophobia and in- difference toward the poor? 15 If we can't, several things will happen. There will be more AIDS cases than need be. Expenses of dealing with AIDS will be higher than they should be, draining resources from other na- tional priorities. And it will cost business more-in inef- ficiency and disruption in the workplace, in employees' lives, in health insurance premiums, and in tax dollars. This need not, and should not be, the case. The business com- munity cannot do this alone. We need partners. It will take a concerted and cooperative effort-federal, state and local governments, business, labor, our educational institutions, the religious community, health care profes- sionals, and private citizens. As a nation, we are good at facing local, limited emergencies-quenching forest fires, rescuing a tiny child from an abandoned Texas well, or freeing whales from the ice in Alaska. But can we pull together as a nation to face this emer- gency of national proportions? I believe we can, if prominent leaders from every segment of society are en- gaged in the battle against AIDS, starting with the Presi- dent of the United States. President Reagan glossed over the findings of his own Presidential Commission. As Vice President, George Bush endorsed the Commission's work, particularly the anti-discrimination recommenda- tions. I am eager for President Bush to tell the nation what his administration will do to address AIDS. The AIDS epi- demic is a rip in the fabric of our society. Left un- mended, it will unravel. If we don't act, the issues of the future won't be the six I've outlined here. There will be only nagging questions: Why didn't we move sooner? Why did we hang back, fearful and timid? And if this comes to pass, the faces we remembered earlier today will haunt us forever. 16 AIDS: A Challenge to Business All of us in business should be asking ourselves the following questions: What will you do when an employee develops AIDS? When an employee is believed to be infected with the AIDS virus? When co-workers refuse to work with a person thought to have AIDS? When an infected employee asks for your help? I urge you to take action. Because this is a crisis situation. ALBERT BOWERS, Ph.D, CHAIRMAN & CEO, SYNTEX CORPORATION San Francisco Chronicle March 14, 1988 17 AIDS cuts across all segments of society. It can disrupt families, schools, communities and work- places. Johnson & Johnson is no exception. Like other corporations, we are committed to the health and safety of our employees and their families. This commitment cannot be met unless we are will- ing to join the effort against AIDS. ANTHONY A. HERRMANN, M.D., VICE PRESIDENT, JOHNSON & JOHNSON Testimony before the Presidential Commission on the Immunodeficiency Virus Epidemic, May 10, 1988 AIDS is on the verge of becoming a multi-billion dollar a year problem for American business-just in terms of lost productivity. These costs will be passed on to corporations and individuals. So it makes sense from a purely practical point of view to invest time and money in the effort to deal with this social issue. And these economic considerations add to- not detract from-our very human response to the suffering associated with AIDS. RICHARD J. HAAYEN, CHAIRMAN & CEO, ALLSTATE INSURANCE COMPANY Allstate Forum on Public Issues, AIDS: Corporate America Responds, October 13, 1987 18 A recent survey of U.S. executives ranked AIDS as the third most pressing problem facing the United States, behind the federal deficit and drug abuse. Yet only seven percent of all corporations have an AIDS policy. It's time now for businesses to act. ANN McLAUGHLIN, FORMER SECRETARY, DEPARTMENT OF LABOR AIDS Frontline Healthcare Conference, Washington, D.C., January 9, 1989 Corporate America is long overdue in stepping up to the problem of AIDS as it affects the workplace-and our lives in general. AIDS leaves a trail of sorrow, bitterness, and fear. It can immobilize a workforce. It can damage productivity. No business wants or can afford that. So we must address AIDS directly. AIDS challenges business-as a community and a family-to renew our commitment to love one another today. Because for those with AIDS, there is no tomorrow. ANDREW V. SMITH, PRESIDENT, PACIFIC NORTHWEST BELL Speech before the Seattle Rotary, August 10, 1988 19 Large companies have a duty and responsibility not only to help their employees deal with AIDS, but also to share information, expertise and resources with smaller companies and with the community. AIDS is a community problem. Because of this, it is a problem for business. If we don't unite around our common best interests, AIDS will cause devastating problems for business. BRYAN LAWTON, Ph.D., VICE PRESIDENT & DIRECTOR, EMPLOYEE ASSISTANCE SERVICES, WELLS FARGO BANK Second Annual National Disability Management Conference, Washington, D.C., October 17, 1988 One measure of good corporate management is its ability to assess and adjust to new conditions and needs. Corporate leadership and support in the battle against AIDS are surely logical results of good corporate management. It would also be in the finest tradition of corporate public involvement. STANLEY G. KARSON, DIRECTOR, CENTER FOR CORPORATE PUBLIC INVOLVEMENT Editorial, Response, August 1986 20 The easy work-building a national strategy to deal with AIDS-is over. Now the tough part-implementing that strategy-has begun. Business has a mandate not just to participate, but also to help lead the nation as it undertakes its response to AIDS. It has a mandate because AIDS is a problem of human resources and human capital, and of our ability to compete. And these are fundamentally business problems. ADMIRAL JAMES D. WATKINS (RET.), SECRETARY, DEPARTMENT OF ENERGY AND FORMER CHAIRMAN, PRESIDENTIAL COMMISSION ON THE HUMAN IMMUNODEFICIENCY VIRUS EPIDEMIC Private Sector Leadership Conference on AIDS, Chicago, 1988 Businesses cannot afford to ignore or walk away from the AIDS problem. AIDS will affect the workforce for years to come. If we do not address AIDS now from a business perspective, we might not be able to recoup our losses in the future. RONALD B. EISENHAUER, VICE PRESIDENT, SALES, U.S. CENTRAL AREA, DIGITAL EQUIPMENT CORPORATION Private Sector Leadership Conference on AIDS, Chicago, 1988 21 When nine major corporations band together on any issue, as we have done in the New England Corporate Consortium for AIDS Education, it makes a powerful statement. And we wanted to make a powerful statement to our employees, to other businesses, and to the community at large, that we are concerned for our employees, and for the community as a whole. PETER W. BERTSCHMANN, VICE PRESIDENT, HUMAN RESOURCES, NEW ENGLAND TELEPHONE Testimony before the Presidential Commission on the Human Immunodeficiency Virus Epidemic, May 10, 1988 We must not lose sight of the fact that social problems, including AIDS, affect every sector in society. Corporate America can help to build stronger communities. Stronger communities make for a stronger economy, and that is good for business. ROBERT V. VAN FOSSAN, CHAIRMAN & CEO, MUTUAL BENEFIT LIFE INSURANCE COMPANY Annual Forum, National Assembly of National Voluntary Health and Social Welfare Organizations, Inc., June 1988 22 No one in the private sector can feel that AIDS is someone else's problem. By 1991, in addition to human tragedies, AIDS-related illnesses and premature deaths are expected to cost business and industry more than $50 billion in lost productivity. So we have a clear reason to become involved-not just for altruistic reasons but also because it is in our own self-interest. ROBERT A. BECK, CHAIRMAN EMERITUS, PRUDENTIAL INSURANCE COMPANY OF AMERICA National AIDS Network Skills- Building Conference, New Orleans, October 21, 1988 AIDS offers a window of opportunity for business, as well as the nation. If we can jump the barriers for AIDS, we can also jump them for mental health, low birthweight babies, cancer, heart disease and the litany of plagues in American health. The real cost of AIDS will be in lost life. Families will lose loved ones. Industries will lose workers. No one can yet predict the full costs of AIDS to business or to our nation. SANDRA S. PERSON, EXECUTIVE DIRECTOR, HOUSTON AREA HEALTH CARE COALITION Health Agenda 1988, the Washington Business Group on Health and National Association of Manufacturers 23 AIDS: A Need for Civic Responsibility If AIDS is truly "Public Enemy Number One," then all unions have a responsibility to become involved, to push for increased support for research, education, and services to people with AIDS. JOHN J. SWEENEY, INTERNATIONAL PRESIDENT, SERVICE EMPLOYEES INTERNATIONAL UNION AIDS Frontline Healthcare Conference, Washington, D.C. January 10, 1989 24 In a pluralistic society, business, like every other institution, must serve the public interest. AIDS qualifies as one of society's major problems. It's going to become even more serious in the near future. By helping fight AIDS, we can dispel the myth that big business can't act quickly or decisively when confronted with a significant challenge. LAWRENCE H. WILLIFORD, SENIOR VICE PRESIDENT, ALLSTATE INSURANCE COMPANY Fortune Corporate Communications Seminar, LaQuinta, California, March 23, 1988 The question isn't whether business should become involved. It's what can business do. The answer is straightforward. Make sure employees get the real facts about AIDS. Support the activities of worthwhile AIDS groups in the community. Provide financial help to medical and research organizations. AIDS is too big for any one of US to battle alone. Other businesses must join US in this fight. By working together, we can make a real difference. DAVID R. CARPENTER, CHAIRMAN & CEO, TRANSAMERICA OCCIDENTAL LIFE COMPANIES Press Conference for the American Foundation for AIDS Research, Los Angeles, January 14, 1986 25 Companies large and small must move AIDS to the top-or near the top-of their public service agendas. We want people to join with each other-inside and outside the busi- ness community-to emphasize everyone's stake in dealing with this deadly disease. For once and, I hope, for all, busi- ness can make a difference. In the process, we can demonstrate that business believes in values beyond the bottom line. We can show that when the call to care was sounded, corporate America answered. HERBERT E. LISTER, CHAIRMAN, ALLSTATE INSURANCE COMPANY Allstate Forum on Public Issues, AIDS: Corporate America Responds, January 20, 1988 AIDS raises serious questions for business, not the least of which is how we can prepare not just our employees but also our communities. If we start working together now, we can come up with answers that will help us deal with this problem fairly and responsibly. CHARLES E. McKITTRICK, JR., VICE PRESIDENT, GOVERNMENTAL PROGRAMS, INTERNATIONAL BUSINESS MACHINES Press conference announcing the formation of the Washington Metropolitan Area Business Leadership Task Force on AIDS, January 11, 1989 26 The scientific, medical, and educational progress needed to control AIDS will depend largely on support from all influential elements of society, including business leaders like yourselves. / urge the leaders of American business to do their part. Because business leaders can exert a very constructive influence on the outcome of this epidemic. P. ROY VAGELOS, M.D., CHAIRMAN & CEO, MERCK & COMPANY Address to The Business Council, October 10, 1987 Business must be involved in the fight againt AIDS. First and foremost, it must educate its employees. But it can do far more. Business can support community-based AIDS organizations and activities. It can reach out to minorities, drug abusers and young people. The possibilities for making a major impact are limitless. RICHARD S. SCHWEIKER, PRESIDENT, AMERICAN COUNCIL OF LIFE INSURANCE PROJECT HOPE Conference on the Socio-Economic Impact of AIDS on Health Care Systems, Washington, D.C., March 25, 1987 27 AIDS must be a national priority. There's lots to do in combatting AIDS. The work starts with communication. Each of US in business has a responsibility to communicate as authoritatively as possible the AIDS story, and to do it often. JOHN B. CARTER, PRESIDENT & CEO, EQUITABLE LIFE ASSURANCE COMPANY Interview, Insurance Compensation, October 1987 Labor has an important role to play in the AIDS crisis. My union has made a commitment. We are working to make sure that all the recommendations made by the Presidential Commission and the Institute of Medicine are adopted, from the federal government all the way down to the workplace. Other unions must make the same commitment. JORDAN A. BARAB, OCCUPATIONAL SAFETY AND HEALTH COORDINATOR, AMERICAN FEDERATION OF STATE, COUNTY AND MUNICIPAL EMPLOYEES Private Sector Leadership Conference on AIDS, Chicago, 1988 28 We have a strong pluralistic tradition in this country, a history of mixing public and private sector roles. This should be the foundation for our fight against AIDS. State risk pools can address the problem of the medically uninsured. Medicaid could be expanded to pay the full costs of appropriate care for all the poor. Incentives and subsidies should be used to maintain private insurance for those who become disabled and lose their employee benefits. Case management should be encouraged. Laws against discrimination in employment must be enforced. And we must prohibit the use of sexual orientation in underwriting. CARL J. SCHRAMM, PRESIDENT, HEALTH INSURANCE ASSOCIATION OF AMERICA Testimony before the Presidential Commission on the Human Immunodeficiency Virus Epidemic, April 27, 1988 29 Unions historically have responded to broad social problems, including hunger, illiteracy, and disenfranchisement. Now, we must expand these efforts to include AIDS. As representatives of working men and women, unions are uniquely situated to confront and dispel people's fears about AIDS. We have an historic obligation to fight discrimination. As the number of those with AIDS increases, we have a responsibility to ensure that those with AIDS, as well as all Americans, have access to the best, highest quality health care services. MARGARET M. SEMINARIO, ASSOCIATE DIRECTOR, DEPARTMENT OF OCCUPATIONAL HEALTH, SAFETY AND SOCIAL SECURITY, AFL-CIO Private Sector Leadership Conference on AIDS, Chicago, 1988 30 AIDS challenges business and our community. It is a challenge that cannot be ignored. In Washington, D.C., businesses have joined with academia, medicine, religious institutions, local government and community groups to pool their expertise and resources to address this problem. The Board of Trade encourages this active business response. WILLIAM F. SINCLAIR, PRESIDENT, GREATER WASHINGTON BOARD OF TRADE Press Conference announcing the formation of the Washington Metropolitan Area Business Leadership Task Force on AIDS, January 11, 1989 By working together, organized labor, the schools, business, government, the health care industry, parents and community organizations can create an effective partnership to help prevent the transmission of HIV and meet the needs of all in the community who suffer from this terrible disease. AL SHANKER, PRESIDENT, AMERICAN FEDERATION OF TEACHERS AIDS Education Project Report, March 1989 31 AIDS stands for Acquired Immune Deficiency Syndrome. It also means "American Industry Do Something!" Syntex did something in the battle against AIDS. We believe all businesses should. Why? Because this is an unprecedented epidemic. Because it will be a long time before there will be a vaccine or a cure. Because education about the epidemic is essential. And most importantly, because we believe strongly that business can, and should, make a difference. GWYNN C. AKIN, Ph.D., DIRECTOR OF HEALTH POLICY, SYNTEX CORPORATION Private Sector Leadership Conference on AIDS, Chicago, 1988 32 AIDS: A Call for Leadership AIDS challenges every segment of society. Why are we waiting to do something until we are in a crisis situation? I can't tell you the passion that's out there in this country waiting for the leadership to say "OK, we're beyond the rejection and the denial and the vilification of others and we're ready to wage war on the virus rather than on groups of people." It won't be an easy war. For me, the military was a lot easier. Being Chief of Naval Operations at the Joint Chiefs of Staff was a piece of cake compared with AIDS. ADMIRAL JAMES D. WATKINS (RET.), SECRETARY, DEPARTMENT OF ENERGY AND FORMER CHAIRMAN, PRESIDENTIAL COMMISSION ON THE HUMAN IMMUNODEFICIENCY VIRUS EPIDEMIC PBS AIDS Quarterly, February 28, 1989, produced by WGBH Boston 33 What the nation needs is leadership, a commitment by heads of corporations, public officials, leaders of community groups and charitable organizations, to direct our energies to defeating AIDS. If we are strong enough to accept the challenges of leadership, the defeat of AIDS could be our finest hour as a caring people. JOHN J. CREEDON, PRESIDENT & CEO, METROPOLITAN LIFE INSURANCE COMPANY National AIDS Awareness Test, September 15, 1987 AIDS, although already in epidemic proportions, seems easy to ignore since it does not yet touch most of us personally. But it will. And it will touch us with disastrous potential. For precisely this reason, chief executive officers, presidents, and chairmen must assert themselves now, and take an aggressive leadership position on AIDS. BENNEVILLE N. STROHECKER, PRESIDENT, HARBOR SWEETS You Can Do Something About AIDS, Second Edition (in press) 34 It is sometimes said that the most important quality a newspaperman can have is a sense of outrage-outrage at human injustice and at the ineffectiveness of government and institutions in times of crisis. Well, AIDS is a crisis-of human, economic, medical, social, ethical and political proportions. It's time for the leaders of America-those in government, medicine and business-to hone their own senses of outrage and begin leading. SAM S. McKEEL, PUBLISHER AND CHAIRMAN, PHILADELPHIA NEWSPAPERS, INC. Private Sector Leadership Conference on AIDS, Chicago, 1988 Business must accept AIDS as a special problem, in the workplace, and in the community. Business can assume a leadership role, and point the way. The absence of our leadership will convince others that AIDS is really not an important problem. THEODORE COOPER, M.D., Ph.D., CHAIRMAN & CEO, THE UPJOHN COMPANY AND CHAIRMAN, COMMITTEE FOR THE OVERSIGHT OF AIDS ACTIVITIES, INSTITUTE OF MEDICINE Private Sector Leadership Conference on AIDS, Chicago, 1988 35 Management and labor must join forces on AIDS. Now is the time to fulfill the definition of the term "leadership" by working together-to increase knowledge, reduce fear, and fight prejudice. Most importantly, management and labor must foster public concern and compassion for those living with HIV. MARY HATWOOD FUTRELL, PRESIDENT, NATIONAL EDUCATION ASSOCIATION Conference on AIDS Education in the Schools, Atlanta, May 1988 There's a widespread misconception among corporate executives that getting involved with AIDS spells disaster. That the safest route is to do nothing. But our employees, our companies, our communities, our country face a crisis. There is no excuse for inaction. People are looking for leadership. If you give it, you'll be the leader. TERRY M. MULREADY, VICE PRESIDENT-EXTERNAL AFFAIRS/CORPORATE COMMUNICATIONS, PACIFIC BELL Speech to The Arthur Page Society, September 28, 1987 36 I'm very proud of Digital Corporation for putting a stake into the ground and showing corporate leadership both in the community and within our company. I firmly believe that as business leaders, we must bring our skills to bear on AIDS. We must go forth into the communities where we are known and work. There, we can make the difference we surely were meant to make. PAUL A. ROSS, Ed.D., MANAGER, AIDS PROGRAM OFFICE, DIGITAL EQUIPMENT CORPORATION AIDS in the Workplace Symposium, Harvard University, March 16, 1989 AIDS is not going to go away any time in the near future. And as with any other issue of concern to workers and their communities, the need for leadership from labor has never been more clear. WILLIAM K. BORWEGEN, DIRECTOR, OCCUPATIONAL HEALTH AND SAFETY, SERVICE EMPLOYEES INTERNATIONAL UNION AFL-CIO Community Services Annual Convention, June 13, 1988 37 Employees, communities and stockholders may not hold American business accountable today for helping to fight AIDS. But they will tomorrow. Business leaders often ask what they can do. I tell them to watch what companies in San Francisco, New York, Boston, places where the problem is more acute, are doing. They are providing models of corporate leadership and responsibility. Their example should be an example for American business. ARTHUR H. WHITE, PRESIDENT & CEO, WSY CONSULTING GROUP, INC. Private Sector Leadership Conference on AIDS, Chicago, 1988 38 Coming from Detroit, I learned as a child that what's good for General Motors is good for the country. Well, I turn that around and say, "What's good for the country is good for American business." AIDS is the societal challenge of the Eighties, the Nineties, and the next hundred years. It also presents an opportunity for real pioneering in corporate leadership. You have a chance to do something you've never done before. But to lead, you must know the facts. And if you're going to get involved, jump in with both feet. Or don't jump in at all. JAMES W. CURRAN, M.D., M.P.H., DIRECTOR, AIDS PROGRAM, CENTERS FOR DISEASE CONTROL Private Sector Leadership Conference on AIDS, Chicago, 1988 39 Business is a vital force in the community. As such, the primary role for business is to set the tone for leadership as communities mobilize to fight AIDS. Each of US is being given the opportunity to demonstrate the highest standards of compassion and humanitarian support for those affected by this terrible disease. SANFORD CLOUD, JR., VICE PRESIDENT, CORPORATE PUBLIC INVOLVEMENT, AETNA LIFE AND CASUALTY FOUNDATION Start now, because the clock is ticking. Government and the private sector must work together on AIDS. But nothing will happen unless you make it happen. The key is your leadership. OTIS R. BOWEN, M.D., FORMER SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Address to The Business Council, October 10, 1987 40 Board of Directors Edward N. Brandt, Jr., M.D., Ph.D. College of Medicine, Oklahoma University, Chair J. Richard Munro Time Inc., Vice Chair Karen Ignagni AFL-CIO, Secretary Michael Pollard Michaels & Wishner, P.C., Treasurer B.J. Stiles President Gwynn C. Akin, Ph.D. Syntex Corporation Lewellys F. Barker, M.D. American Red Cross Erline Belton Digital Equipment Corporation Sharon Canner National Association of Manufacturers Jane Delgado, Ph.D. National Coalition of Hispanic Health and Human Services Organizations Richard Dunne Gay Men's Health Crisis William R. Hendee, Ph.D. American Medical Association Stephen E. Herbits Joseph E. Seagram & Sons, Inc. Stanley G. Karson Center for Corporate Public Involvement G. Douglas Lawrence, Jr. International Business Machines Corp. Bryan Lawton, Ph.D. Wells Fargo Bank Stephen T. Moskey AEtna Life & Casualty T.M. (Terry) Mulready Pacific Bell Woodrow A. Myers, Jr., M.D. Indiana State Board of Health Ed Pitt National Urban League Beny J. Primm, Jr., M.D. Addiction Research Treatment Corporation Mervyn F. Silverman, M.D. American Foundation for AIDS Research The Rt. Rev. William E. Swing Episcopal Diocese of California Larry H. Williford Allstate Insurance Company 41 Roster of Members BUSINESS AND LABOR Abbott Laboratories Abt Associates Addiction Recovery Corporation AEtna Life & Casualty Allstate Insurance Company American Brands, Inc. American Council of Life Insurance American Federation of Labor and Congress of Industrial Organizations American Federation of State, County, & Municipal Employees American Federation of Teachers American Telephone & Telegraph Apple Computer, Inc. Associated Madison Companies, Inc., a Subsidiary of Primerica Corporation Association of Labor Management Administrators and Consultants on Alcoholism, Inc. Baltimore Gas & Electric Company Blue Cross Blue Shield Association Bristol-Myers Company Burroughs Wellcome Company Caremark Homecare Centel Corporation Chevron, U.S.A., Inc. Digital Equipment Corporation The Equitable Life Assurance Society General Electric General Mills, Inc. Group Health Association of America Health Industry Manufacturers Association Health Insurance Association of America Hoffmann-La Roche Inc. Institute for Disease Prevention in the Workplace International Business Machines Corp. Johnson & Johnson Joseph E. Seagram & Sons, Inc. Levi Strauss & Co. Levine, Huntley, Schmidt & Beaver Loews Hotels Corporation Marshall Field & Company Mead Corporation Mercantile and General Reinsurance Company plc. Metropolitan Life Insurance Co. Mobil Oil Corporation NCR Corporation 42 National Association of Chain Drug Stores National Association of Home Builders National Association of Manufacturers National Education Association Ogilvy & Mather Pacific Bell Pharmaceutical Manufacturers Association Philip Morris Inc. Playboy Enterprises, Inc. The Principal Financial Group The Prudential Insurance Company of America Scott Paper Company Security Life of Denver Security Pacific Corporation Service Employees International Union Squibb Corporation Syntex Corporation Time Inc. Transamerica Occidental Life Insurance Co. Union Carbide United Food and Commercial Workers Wells Fargo Bank NATIONAL VOLUNTARY, RELIGIOUS, AND EDUCATIONAL ORGANIZATIONS AND ASSOCIATIONS Academy for Educational Development AIDS Action Council AIDSFILMS, Inc. American Academy of Family Physicians American College of Cardiology American College Health Association American Health Care Institute American Hospital Association American Institutes for Research American Lung Association American Medical Association American Nurses Association American Pharmaceutical Association American Psychological Association American Public Health Association American Red Cross American Society of Hospital Pharmacists Association of American Medical Colleges The Association of Junior Leagues, Inc. Catholic Charities, USA Catholic Health Association Center for Community Change Center for Population Options Children's Defense Fund The Episcopal Church Center Health and Welfare Ministries, General Board of Global Ministries, United Methodist Church 43 Healthcare Financial Management Association Human Interaction Research Institute Human Rights Campaign Fund National AIDS Network The National Assembly of National Voluntary Health & Social Welfare Organizations, Inc. National Association of People With AIDS National Coalition of Hispanic Health and Human Services Organizations National Council of Churches AIDS Task Force National Council of La Raza The National Foundation for Infectious Diseases National Gay & Lesbian Task Force National Health Council The National Hemophilia Foundation National Hospice Organization The National Kidney Foundation National Minority AIDS Council Public Relations Society of America The Salvation Army Society for the Right to Die The Stop AIDS Resource Center United Church Board of Homeland Ministries United Way of America Volunteers of America LOCAL AND REGIONAL ASSOCIATIONS, VOLUNTARY, RELIGIOUS, AND EDUCATIONAL ORGANIZATIONS AID Atlanta AIDS Foundation of Chicago AIDS Resource Center Citizens Commission on AIDS for the New York City- Northern New Jersey Region Concern for Dying Gay Men's Health Crisis Howard Brown Memorial Clinic Instituto Familiar de la Raza-Latino AIDS Project Mothers of AIDS Patients New York University (School of Education, Health, Nursing and Arts Professions) Philadelphia AIDS Task Force Philadelphia Commission on AIDS San Francisco AIDS Foundation Whitman-Walker Clinic GRANTMAKING ORGANIZATIONS American Foundation for AIDS Research Design Industries Foundation for AIDS The Hunt Alternatives Fund Pettus-Crowe Foundation 44 "The AIDS epidemic is a rip in the fabric of our society. Left unmended, it will unravel " " a solid publication which will assist managers in building and improving on business AIDS education programs." C. Everett Koop, M.D. Surgeon General AIDS Publishers: American Foundation for AIDS Research American Council of Life Insurance Health Insurance Association of America Sponsors: AIDS National Interfaith Network EDUCATION American Federation of TV and Radio Artists American Hospital Association American Medical Association American Red Cross California Business Roundtable A Business Guide Citizens Commission on AIDS League of Women Voters of the United States Minority AIDS Project National AIDS Network National Association of Manufacturers National Conference of Christians and Jews National Leadership Coalition on AIDS National PTA (National Congress of Parents and Teachers) National Small Business United Screen Actors Guild The Business Roundtable United Auto Workers/General Motors United Way of America United States Conference of Mayors FOREWORD AIDS Education: A Business Guide represents the combined efforts of several groups to produce a comprehensive guide to AIDS education in the workplace. This guide addresses the need for a basic manual that describes principles and programs for AIDS education in the workplace. The U.S. Department of Labor estimates that the work force comprises 66.1% of the American population. Because so many people can be reached there, the workplace is one of the primary targets for AIDS education. Fifty thousand copies of this manual will be distributed to American businesses and companies; the initial mailing will be provided at no cost. It is designed to assist managers, human resource departments, and CEOs in planning and implementing AIDS education programs for their employees. Also, it seeks to avoid unnecessary duplication of effort in establishing AIDS education programs by describing resources already available to businesses and companies. This manual was originally developed as a project of and in consultation with the Orange County, California Business Leadership Task Force on AIDS and Alcohol & Drug Abuse convened and chaired by the Chairman of the Executive Committee of Pacific Mutual, Walter B. Gerken, and Pacific Mutual's Chairman of the Board and Chief Executive Officer, Harry G. Bubb. Pacific Mutual coordinated, staffed, and underwrote the development of Facilitating AIDS Education in the Work Environment, the first edition of this manual. Some of the material was obtained from and used with the permission of the San Francisco AIDS Foundation. The Project Director was Robert G. Haskell, Second-Vice President, Pacific Mutual. Suzanne D. Hoehl of Pacific Mutual's Corporate and Public Affairs Department was the Project Coordinator. This edition was revised by the American Foundation for AIDS Research (AmFAR). Steven S. Chapman, a loaned executive from AT&T, was Project Manager. New material was contributed by Trish A. Halleron, M.P.H., AmFAR Director of Education. The following individuals reviewed the manuscript and offered other valuable assistance: Mathilde Krim, Ph.D, founding Co-Chair, AmFAR; Suzanne Hoehl, Pacific Mutual; Eve Katz, Director of Public Affairs Projects for the American Council of Life Insurance (ACLI) and the Health Insurance Association of America (HIAA); Michael Samuels, Dr.P.H., Chair of the Department of Health Administration, School of Public Health at the University of South Carolina, and former Assistant to the Surgeon General; Jerry Wagner, United Auto Workers/General Motors Human Resource Center; Patricia Morrow, former Corporate Liaison for AmFAR; Mary M. Anderson, California Business Roundtable; and Alan Pardini, Harder Kibbe Research & Consulting. The publishers gratefully acknowledge the support and contribution of these individuals. The costs incurred in the development and distribution of this manual were under- SERVICES Public Health Service HUMAN written by the following: DEPARTMENT OF HEALTH & HUMAN SERVICES HEALTH The Surgeon General of the Drexel Burnham Lambert Public Health Service Rockville MD 20857 AT&T Pacific Mutual American Council of Life Insurance Health Insurance Association of America August 1, 1988 The following organizations have reviewed this manual and are sponsors of it. They agree in principle with its concept and con- Scott J. Tilden tents, and support its distribution: Executive Director, American Foundation for AIDS Research Richard S. Schweiker AIDS National Interfaith Network President, American Council of American Federation of TV and Life Insurance Radio Artists Carl J. Schramm President, Health Insurance American Hospital Association Association of America American Medical Association Dear Messrs. Tilden, Schweiker and Schramm: American Red Cross California Business Roundtable for the opportunity to review pleased the draft that the of AIDS previous Citizens Commission on AIDS Thank Education: edition, you Facilitating A Business AIDS Guide. Education edition I am in is the comprehensive Work Environment, and well- spread was League of Women Voters of the United States well designed received. and will This support updated is a corporate solid publication efforts to which contain education will the assist Minority AIDS Project of managers HIV infection. in building It and improving on their AIDS National AIDS Network National Association of Manufacturers programs. American Foundation for AIDS Insurance Research, Association the American of America, Council National Conference of Christians and Jews The of and Life Insurance, sponsors should the Health be congratulated outstanding for example collaborating of the private on National Leadership Coalition on AIDS this your venture. Your responsibility work is an for an leadership issue of and major initiative. importance National PTA (National Congress of sector's to American assuming society. I applaud your Parents and Teachers) Sincerely yours, National Small Business United Screen Actors Guild The Business Roundtable C. Everett Koop, M.D. Surgeon General United Auto Workers/General Motors United Way of America United States Conference of Mayors TABLE OF CONTENTS AIDS EDUCATION: A Business Guide Editor Impact on Business and Society 1 Lee E. Klosinski, Ph.D. How to Run an AIDS Employee Education Program 3 First Edition, Facilitating AIDS Education in the Work Environment Copyright © September, 1987 by Pacific Mutual Life Insurance Understanding AIDS 17 Company Second Printing November, 1987 Integration of Benefits 21 Revised Edition, AIDS EDUCATION: A Business Guide Copyright © September, 1988 by the Appendices 25 American Foundation for AIDS Research, the American Council of Life Insurance, Resources 25 and the Health Insurance Association of America. All rights reserved. No part of Common Questions and Answers About AIDS 33 this publication may be reproduced in any form or language without written permis- Centers for Disease Control Guidelines 43 sion from the Publishers. For such permis- sion, please contact the American Founda- OSHA Enforcement 44 tion for AIDS Research. 1 CHARTER IMPACT ON BUSINESS AND SOCIETY As of the summer of 1988, over 68,000 cases of AIDS have been diagnosed in the United States alone. As alarming as this figure is, the worst years of the AIDS epidemic are yet to come. The impact of AIDS on society is inevitable. It will be felt in terms of human suffering, the loss of productivity, and increased taxes, and health care bills. CDC Projections of It is estimated that at this time 1.5 million persons in the U.S. alone are infected with HIV New Cases of AIDS In the U.S. 1988-1992 (human immunodeficiency virus), the viral agent responsible for causing AIDS. The current projection of the Centers for Disease Control is that by 1993 there will be 365,000 cases 80,000 of full-blown AIDS. Many scientists have projected that all of those infected with HIV will eventually develop HIV-related illnesses or AIDS. Of course, the greatest 70,000 impact and expense to businesses and society is the loss of human life. 60,000 Large and small companies alike are seeing that they are not 50,000 immune to HIV-related illnesses. American businesses will feel 40,000 these costs in terms of losses in productivity, higher insurance 30,000 expenses, and possible costly litigation. Concern about AIDS 20,000 and its transmission in the workplace can also impact businesses by causing fear and work disruption. Companies will need to 10,000 develop cost-effective health care programs, as well as strategies 1988 1989 1990 1991 1992 to communicate information about health benefits and company policy on HIV-infected individuals to employees. 50,265 total cases at the end of 1987 365,000 total cases estimated at the beginning of 1993 2 AIDS Education: A Business Guide Health Care Costs Economists have estimated that the total annual U.S. costs associated with AIDS may reach $66.4 billion in 1991, up from $8.7 billion in 1986. Personal medical care costs alone are projected at $8.5 billion for 1991. The large increase in costs projected for 1991 is explained by the dramatic increase in the number of cases of full-blown AIDS estimated by the Centers for Disease Control. Hospitalization accounts for 80-90% of the direct medical costs of treating HIV-related illnesses. Lifetime treatment costs for persons with AIDS range from $24,500 to $147,000 per patient. These costs vary because the presence of local support services and out-patient care reduces the cost of patient care. Productivity Costs Because HIV-related illnesses generally strike persons 25 to 44, significant productivity is lost due to illness, disability, and premature death. Among this age group, AIDS is second only to cancer as a cause of death. By 1991, AIDS will account for 12% of all income lost due to illness; the annual costs of illness and death from AIDS will be over $55 billion in productivity. Paying for the AIDS Epidemic Methods of treating AIDS are evolving, and assumptions about current and future infection in the population are problematic. As a result, projecting national costs for personal medical care of AIDS is difficult. Estimates for 1986-1991 have gone as high as $112.5 billion. One thing is certain: the cost of this epidemic will continue to spread throughout society, increasingly affecting the private sector, which will encounter larger bills The Cost of the Epidemic (in billions of dollars) for benefits and productivity losses. '85 '86 '91 Federal support of AIDS education, research, and treatment Medical Care $0.6 $1.1 $8.5 has expanded in recent years. In fiscal year 1988, the federal Research, education and 0.3 0.5 2.3 outlay for AIDS-related Public Health Service programs and screening Medicaid benefits will be over $1.3 billion. By 1991, an Lost wages from disability 3.9 7.0 55.6 estimated $2.3 billion will be spent by the federal government and death alone on research, blood screening, education, and support Total $4.8 $8.6 $66.4 services. State and local governments provide funds for HIV- related illness through state obligations for Medicaid, and Source: Anne Scitousky, Palo Alto Medical Foundation/Research Institute (1987) education and social services programs. Higher taxes will be required to fund state and local governments facing shortages of facilities and staff to provide necessary care. Through government funding, business and corporate leadership, and individual responsibility, the future course of the AIDS epidemic can be controlled. 3 C H PTER HOW TO RUN AN EMPLOYEE AIDS EDUCATION PROGRAM As the AIDS epidemic continues to spread, its consequences will increasingly be felt in the workplace. Employers will be forced to confront issues related to AIDS such as employee fears, company policy decisions, and benefits programs. Education is the best prevention against spread of this disease as well as the best guarantee that workers will respond rationally and compas- sionately to a co-worker with AIDS. American businesses can play a leading role in AIDS education as they already have with other employee welfare concerns like physical fitness and smoking reduction. Employees need to know that AIDS is a preventable disease and that there is no risk of transmission through casual contact in the workplace. Com- Employees need to know that AIDS is pany-based education programs can provide factual, non-judgmental a preventable disease and that there is information to employees and their dependents. no risk of transmission through casual The following steps can assist in planning a consistent and comprehensive employee education program: contact in the workplace Educate top management and solicit their support. If a collective bargaining unit exists, include its leadership in this process. This support should then be announced to all employees. The remainder of the staff is then educated, with each manager able to take some responsibility for facilitating the education of his or her staff. 4 AIDS Education: A Business Guide Establish a Resource/Education Committee com- Responding to AIDS: Ten Principles for the Workplace posed of managers and employees. This increases 1 People with AIDS or HIV (Human Immunodeficiency Virus) infection the sense of ownership and acceptance for any are entitled to the same rights and opportunities as people with other serious or life threatening illnesses. program developed. Composition of the committee should include representatives from human 2 Employment policies must, at a minimum, comply with federal, state, and local laws and regulations. resources, legal, medical, labor, management, communications, housekeeping, EAP, and special 3 Employment policies should be based on the scientific and interest groups. Once selected, these representatives epidemiological evidence that people with AIDS or HIV infection do not pose a risk of transmission of the virus to coworkers through ordinary need to be educated about the issues surrounding workplace contact. AIDS, the company's policies, and the availability of community resources. 4 The highest levels of management and union leadership should unequivocally endorse nondiscriminatory employment practices and Once trained, this committee can work together educational programs about AIDS. to design the company's AIDS educational program, 5 Employers and unions should communicate their support of these respond to employee questions and concerns, and policies to workers in simple, clear, and unambiguous terms. promote a positive attitude about AIDS. 6 Employers should provide employees with sensitive, accurate, and up-to-date education about risk reduction in their personal lives. It may be helpful to your business or company to use the committee process to develop your 7 Employers have a duty to protect the confidentiality of employees' medical information. program. However, any individual appointed to organize an employee education program can easily 8 To prevent work disruption and rejection of coworkers of any employee handle the task with the assistance of this manual with AIDS or HIV infection, employers and unions should undertake and the utilization of local resources. The use of education for all employees before such an incident occurs and as needed thereafter. a committee or an individual to direct the AIDS 9 Employers should not require HIV screening as part of general pre- education program will be determined by the needs employment or workplace physical examinations. of individual companies. 10 In those special occupational settings where there may be a potential Decide on the information needs for the company risk of exposure to HIV (for example, in health care, where workers and its employees. This should include: may be exposed to blood or blood products), employers should provide - Why AIDS is not contagious at the work site. specific, ongoing education and training as well as the necessary equipment to reinforce appropriate infection control procedures and ensure that - How HIV is spread. they are implemented. - What behavior puts one at risk, and how those individuals at risk can change their behavior. The Citizens Commission on AIDS for New York City and Northern New Jersey - Why the stigma that accompanies the diagnosis is a private, independent group of prominent business, union, and civic leaders. of AIDS often leads to irrational and unfair be- It was established by a consortium of 17 private foundations to develop leadership havior. in meeting the challenges of AIDS. They developed principles for the workplace as a framework for policy development to be offered to employers, unions, and Identify the special needs of specific audiences (e.g., other employee and business organizations for their endorsement. A fuller report non-English speaking/reading, parents, etc.) within can be obtained by writing to: Carol Levine, Executive Director, Citizens Commission the general employee population. on AIDS, 51 Madison Avenue, Room 3008, New York, New York 10010. How to Run An Employee AIDS Education Program 5 Plan educational strategies. Educational materials and programs about AIDS are available from numerous sources (see the Resources section in this manual). Collect a variety of materials for the Resource/Education Committee to review. Several pamphlets are available in Spanish and various Asian languages. Education materials made available to employees should be medically accurate, non-judgmental, and deliver a consistent message. Delivery of the AIDS education program needs to be more than a one-time effort. People learn at different rates and through different methods. Thoughtful planning can provide AIDS information in a variety of forms: brochures, videos, posters, and workshops. A combination of approaches ensures that the greatest number of people will be reached. Utilize established communication The National AIDS Information Clearing- channels within the company: payroll stuffers, in-house newsletters, house has specialists who can provide data on and in-service meetings. Small companies and large corporations AIDS resources, speakers, services, and edu- will have different needs to consider as they plan their AIDS cational materials to managers who are plan- ning work site AIDS programs. education programs. National AIDS Information Clearinghouse Repetition should be a key element of the program. After an inaugural P.O. Box 6003 communications piece, information can focus on "a fact a month" Rockville, Maryland 20850 or "update on AIDS." Fear reduction and behavior modification 301-762-5111 are not easily accomplished and are impossible without repeated Ordering materials: emphasis of the basic messages. A stream of relevant information 1-800-342-AIDS National AIDS Hotline can reinforce fact-based messages about AIDS to employees and 1-800-458-5231 Bulk Orders give them the ability to confront breaking news stories and new developments concerning AIDS. Some specific forms that AIDS education programs can take include the following: Designating an "AIDS Resource Person" at each plant or office is an important step. This Designate an "AIDS Resource Person" person should be able to answer questions about company policy on benefits and other personnel issues related to AIDS. By using a single individual such as an EAP person, the company can help to ensure the confidentiality of affected employees and the competence of persons giving advice on company policy. Another effective method of reaching employees is through the distribution of brochures. They Brochure and Poster Distribution are a convenient method of providing information about basic facts and available resources such as AIDS hotline phone numbers. The Resources section of this manual provides many suggestions about where brochures and posters can be obtained. Some brochures are specific to the workplace and are appropriate to send to every employee, either through the mail, with paychecks or via your current method of distribution. Other 6 AIDS Education: A Business Guide brochures geared to specific groups, such as gay and bisexual men or intravenous drug users, can be made available to employees in a manner that ensures privacy. Posters displayed on company bulletin boards are useful visual reminders that AIDS is a problem for all of our society and that we all need to know the basic facts. Posters also serve to remind employees that the company is concerned about AIDS and wants its employees to be concerned as well. Video Lending Library Establishing an AIDS video lending library where employees can check out videos for use at home is an effective way of communicating the information to the families and friends of your employees. The Resources section of this manual contains information about a variety of educational videotapes. Employee Meetings and Workshops One effective method of providing education to employees is through group employee meetings or in-service training sessions. They are relatively easy to conduct and are effective in reaching employees. Members of the Resource/Education Committee, or other knowledgeable experts, should conduct the meeting. If you do not have resources within the company, the Health Department, Red Cross or state AIDS Prevention Project Directors (listed in the Resources section of this manual) can provide information about competent speakers who are available for these types of meetings. If you choose to conduct the program yourself, follow these basic steps in planning an effective employee meeting or workshop: When: There are several alternatives as to when to conduct an AIDS workshop. It can be incorporated into an existing employee seminar series. It can be part of a department update session, staff meeting or a specially-planned program. The meeting or meetings can even be conducted during the lunch hour. Who: All employees should be educated. There is no risk of contracting HIV through casual contact in the workplace. Employees need to understand why this is true, and how to prevent transmission of the virus outside the workplace if education programs are going to be effective. Format: Keep it simple. A good program is one that is easy to implement and takes relatively little support. How to Run An Employee AIDS Education Program 7 AIDS Workshop Outline Introduction (5-10 minutes) Welcome Personnel policy (if applicable) Introduce Videotape Videotape (15-30 minutes depending on video selected) Discussion (30 minutes) Highlight important facts discussed in the videotape Respond to questions from the group Closing Remarks and Brochure Distribution (5 minutes) Distribute AIDS information brochures and workshop evaluation forms Highlight company and community resources Stress education and sharing information with family and friends Introduction (5-10 minutes) Begin by welcoming employees to the program and thanking them for taking the time to learn the facts about this deadly disease. Refer to the "Surgeon General's Report on Acquired Immune Deficiency Syndrome" and the brochure "Understanding AIDS." Stress that HIV is not casually transmitted; the vast majority of work sites pose no risk. This program will explain why this is the case. Answer their questions emphasizing there are no "dumb questions" when dealing with a complex disease such as AIDS. If there is a personnel policy regarding AIDS or catastrophic illness, state it. A company policy on AIDS (and other catastrophic illnesses) is useful in conveying information about medical, benefit, and legal issues to all employees. Introduce any videotape you might be showing. Explain that the video provides the basic facts about AIDS and that a discussion will follow. Videotape (15-30 minutes) There are a variety of videotapes available for use during the workshop. (See the Resources section of this manual for information about sources from which to obtain videotapes.) Pay particular attention to the descriptions of these videotapes: some are designed specifically for teenagers, others for an older audience. Preview any video before you use it to ensure that 8 AIDS Education: A Business Guide Understanding AIDS Understanding AIDS Surgeon Report ACQUIRED it is appropriate for your particular employees. Some businesses or companies may wish to add A Message From The Surgeon General DEFICIENCY a special introduction or trailer to existing tapes to customize the video or to provide specific has United States prepanne Best experimportant you health problem and Surgeon General's Report information to their employees. available fighting alled -Pubilic Enemy Number On to you now must President haspirg may easily oderstand about ones brochure on Acquired Immune loved issues Some synagogues, things involved activities discuss Everent Koop Meon General groups responsible STATE SERVICE Deficiency Syndrome Discussion (30 minutes) ommunity understanding AIDS based Este solicitar folleto sobre una copia. SIDA llame publica at 800 en 344 Espanol SIDA BULK Follow the videotape with a brief discussion of the information presented in the videotape. After Para U.S. Public Health Service Department Health doing so, ask for questions from the audience. Services Public Affairs Office Human Rockville 200 Independence Avenue, SW (See the "Common Questions and Answers" Official Buxiness POSTAL CUSTOMER Washington, D.C. 20201 section of this manual for the most frequently- 202-245-6867 asked questions.) A local resource person or health 8404 Reproduction professional knowledgeable about AIDS can be useful in answering employee's questions. The U.S. Public Health Service has produced these two important documents Closing Remarks and Brochure Distribution (5 minutes) dealing with AIDS. The Surgeon General's Report on Acquired Immune Defi- As the program concludes, distribute general ciency Syndrome has received wide circulation. Understanding AIDS was mailed information brochures to the audience. Inform the audience who in the company can provide them to each household in the U.S. These brochures contain basic discussions on HIV, with further information. Also, provide informa- tion about local community resources that are how it is transmitted, the relative risks of transmission, and how to prevent available. Some people may be embarrassed about asking AIDS. They are in the public domain and may be reproduced without any prior questions. Prepare and distribute a confidential workshop evaluation form, and be sure to provide approval. Both are available in Spanish. The Public Health Service encourages space on the form for these questions. Answer them later in a follow-up mailing or employee their reproduction and suggests that businesses and companies add their logo newsletter. to them as a sign of support and increased credibility. Employees may already Close the session by again stressing the importance of AIDS education. Request that people take the be familiar with these pamphlets and they are good starting points for educa- information they have learned and share it with family and friends. tion programs. How to Run An Employee AIDS Education Program 9 Sample AIDS Workshop Evaluation Form AIDS Education Program Confidential Evaluation Form Please do not write your name on this form, as your answers are confidential. We would like your help in evaluating the AIDS Education Program by completing this confidential evaluation form. Your opinion will help US determine how we can best offer this information to other employees. Using the sentence and scale below, please circle the number that best describes your reaction to the AIDS Education Program: No Yes Were the goals of the AIDS Education Program stated 1 2 3 4 5 in a clear and concise manner? Were these goals met? 1 2 3 4 5 Was the Personnel Policy described in a clear and concise 1 2 3 4 5 manner? Was the videotape: Interesting? 1 2 3 4 5 Informative? 1 2 3 4 5 Too basic? 1 2 3 4 5 Too technical? 1 2 3 4 5 Did it address your questions? 1 2 3 4 5 Did it answer your questions? 1 2 3 4 5 Would you recommend it to a friend? 1 2 3 4 5 Did the workshop leader highlight the important facts 1 2 3 4 5 discussed in the videotape? Did the workshop leader lead the discussion period in 1 2 3 4 5 an engaging manner? Did the workshop leader encourage questions? 1 2 3 4 5 Was the workshop leader able to answer questions in 1 2 3 4 5 a clear and concise way? Did the workshop leader respect the opinion of those 1 2 3 4 5 who asked questions? Do you feel that you clearly understand the company's 1 2 3 4 5 policy on AIDS? Do you want/need additional information on AIDS? 1 2 3 4 5 Some employees may have additional questions about AIDS that they were not able to ask, or did not feel comfortable asking. Please write down any additional questions that you have. Do not sign your name. All questions will remain confidential. They will be answered in the near future in another segment of the company's AIDS Education Program. We value your opinion. Please make any additional comments about our company's AIDS Education Program that you wish. All information you share with US will remain confidential. (Please use reverse side to make comments.) 10 AIDS Education: A Business Guide Sample Newsletter Articles and Letters Another useful method of providing information about AIDS is through employee newsletter from Management articles. In addition, a letter from the CEO to every employee demonstrates leadership support and is useful in conveying information about AIDS. It is important to distribute a listing of services and materials available to employees through the company. This will also help to ensure that everyone knows information is available. Here are sample letters and newsletters on AIDS: Sample Employee Letter on AIDS TO: All Employees FROM: Chief Executive Officer SUBJECT: AIDS Awareness and Education Program AIDS, Acquired kills thousands of people annually. In 1981, to homosexual men Immune Deficiency Syndrome, is an infectious when AIDS disease was and which drug first high abusers. risk identified, behavior. It is it now The was clear disease thought in sight. that continues to anyone The be limited danger can to spread contract of AIDS and to AIDS there of society through the is still no vaccine or cure feel no one can afford to be unaware transmitted is so great want that to we help you understand how AIDS is from infection. and how facts. it We is not, and how you can protect yourself the company is introducing an AIDS will Awareness include With this in mind, Program for all employees. The program the most and Education seminars with health experts to discuss In addition, current educational AIDS and to answer your questions. library" we will make videotapes the educational aspects of the program the latest to your infor- families. information about available through a "lending basis to bring the monthly newsletter will discuss placed on Articles in AIDS. AIDS information material will be mation bulletin on boards throughout the company. Educational brochures will be made available for you and your family. of the AIDS Awareness and Education Program misconception is to dispel One goal AIDS. For example, there is a popular with person myths about can be contracted through casual contact The medical evidence a that AIDS virus. This is not true. person who carrying the AIDS sharing work space or telephones with a your risk confirms that full-blown AIDS does not increase intends to has the AIDS infected virus or or developing AIDS. This program anxiety about of rid becoming individuals of misconceptions and unnecessary AIDS. We want to and help Education you Program. Our hope is that is you only through share become informed through the company's will AIDS Awareness family what you learn about AIDS. It this disease. with awareness your that we can prevent the spread of Sincerely, Chief Executive SuranSmitz Officer How to Run An Employee AIDS Education Program 11 Sample Employee Newsletter Article # 1 on AIDS The discovery of any new disease is tions about AIDS abound. For exam- a natural cause for public concern. The ple, contrary to the popular casual- identification of Acquired Immune contact myth, the AIDS virus is not Deficiency Syndrome (AIDS) in 1981 spread through normal daily contact was no exception. What makes AIDS at work, in school, or at home. Edu- unique is that fear is growing among cation programs in the workplace those considered at low risk, despite aimed at dispelling fear and misinfor- scientific assurance that it is not an easy mation about AIDS encourage disease to catch. employees to learn the facts. If you are one of the many who think Here at our company, we have intro- you are at low risk of contracting AIDS, duced a comprehensive work site but who are nevertheless worried education program about AIDS. We about it, it is important to arm yourself hope you will make participation in this with accurate information. AIDS is a program a personal priority. It is fatal disease for which there is currently important for all of US to recognize that neither a cure nor a vaccine. Public we can all join the battle against AIDS education on the subject of AIDS is of by fighting fear with the facts. paramount importance. Misconcep- Sample Employee Newsletter Article # 2 on AIDS Acquired Immune Deficiency Syn- ciency virus or HIV. The virus attacks drome (AIDS) is a deadly disease which the body's immune system, making it was first identified in 1981. By mid- vulnerable to opportunistic infections 1988, there had been more than and cancers which, in turn, result in 68,000 cases of AIDS reported in the fatalities. There is no vaccine or cure United States alone. yet, but research is in progress. There is a specific blood test which can tell Despite all the bad news about AIDS, whether an individual has been there is some good news. Scientists infected with the virus. have discovered a great deal about viruses and the function of the immune HIV is difficult to catch. The virus is not system. This information has enabled easily spread from person to person scientists to reach certain conclusions and has never been spread by casual about how the AIDS virus is and is not contact. For the virus to infect, it must transmitted. be in a life-sustaining, chemically- balanced liquid environment. For The cause of AIDS is a specific virus known as the human immunodefi- Continued on page 12 12 AIDS Education: A Business Guide Sample Employee Newsletter Article # 2 on AIDS Continued from page 11 transmission of the virus to occur from breast milk. Saliva, sweat, urine, and person to person, both the virus and tears are not life-sustaining fluids for susceptible, uninfected cells must be in cells. They are not examples of fluids a liquid environment that sustains both in which transmission of HIV infection the virus particles and cell life. The can occur. Nor is transmission caused fluids that offer the virus the environ- by sneezing or coughing. AIDS is not ment needed for infection to occur are transmitted through preparation or blood, semen, vaginal fluids, and serving of food or beverages. Medical authorities who have studied tens of thousands of cases agree that AIDS is contracted in these four ways: Sexual intercourse (vaginal, anal, or oral) with a person who is infected with HIV; Sharing intravenous drug needles or syringes with an infected person; Injection of HIV-contaminated blood or blood products; this method of transmission has become very rare because blood is now being screened for contamination; A woman infected with HIV who becomes pregnant can pass it to her baby. No cases of AIDS have resulted from Our company has not yet had to deal the type of casual contact found in the with a person with AIDS, but if and workplace. No cases have ever been when it happens, it is our hope that linked to sharing typewriters, tele- our employees will be well-informed, phones, tools, papers, water fountains, act rationally, and give the same chewed pencils, eating facilities, show- support and concern they would like ers, or even toilet seats. to get themselves if they had a serious disease. How to Run An Employee AIDS Education Program 13 Sample Employee Memo on AIDS and the Workplace INTEROFFICE MEMO Our company is committed to providing a work environment which allows all of US to perform our jobs in a safe and productive manner. Our business philosophy, which states that we respect the dignity and worth of every person, reinforces this commitment, as does our Equal Employment Opportunity statement, which explains our policy and practice with respect to prohibiting discrimination in every phase of employment. Employees with a disability or medical condition (life threatening or otherwise), who are able to meet, with reasonable accommodations, adequate performance standards and whose continued employment does not pose a current threat to the health and safety of others are assured equal employment opportunities in their employment here. This has been and continues to be the policy and practice of our company. I am reemphasizing this policy because of the media attention currently being given to Acquired Immune Deficiency Syndrome (AIDS) and its impact on the workplace. Any employee who contracts AIDS will be guaranteed the same rights as any other employee who has a handicap or illness. The "AIDS Issue" is surrounded by myths and misunderstandings. To deal with it openly and honestly in the workplace, we must begin with the facts. Over the next couple of months, we will introduce special educational programs providing factual, medical information on AIDS, how it can be transmitted and, more importantly, how it cannot be transmitted. This should help to dispel rumors, lessen fears, and raise our comfort level about this dreaded disease. If you have questions or need assistance at any time, please contact either EEO Administration or Employee Relations. 14 AIDS Education: A Business Guide Questions and Answers About Business Q What special challenges will our company's managers face in dealing with employees with Education and AIDS AIDS and how can I assist them? A A manager must first address his or her own fears about AIDS. Each manager must be assured that there is no risk of transmission in the workplace. Then a manager needs to be prepared to deal with confidential information. Further, he or she needs to be prepared to deal compassionately with the special needs of the person with AIDS. The manager must also be prepared to address the concerns of other employees: he or she may need strategies to deal with crisis intervention among employees fearful of working with a person with AIDS. It may be useful to hold a "For Managers Only" session on AIDS to discuss the special issues that a manager will face when confronted with an employee or employees with AIDS. Perhaps a panel with a personnel representative, medical and legal counsel, and an AIDS educator could provide the necessary additional information that managers need to deal with the issues surrounding an employee with AIDS. Q Since AIDS is primarily a sexually-transmitted disease and information about its transmission frequently contains sexually explicit material, not all employees may want or need it. How can I respect the sensitivities of my employees? A One possible way to distribute this information to employees without offending anyone is to do a mailing of the information to all employees. This should be done using a sealed envelope, and on the envelope something similar to the following could be printed: "Please note that the information contained in this packet discusses sexual material surrounding AIDS risk reduction." Q What is the best response to the following question: "Why is this company keeping on its payroll perverts, drug addicts, and other immoral people, in violation of everything that religion and America stand for?" A This company is not taking a stand one way or the other on these "moral" issues. We are saying that if one of our employees, to whom we have some responsibility as employers, comes down with a disease that is not a threat to anyone in the workplace, we will treat that disease the same way we would treat any other disease. We do not make any moral judgments about any other disease. If someone got lung cancer, we would not say, "Well, it's his fault because he smoked for years." If someone got heart disease, we would not How to Run An Employee AIDS Education Program 15 say, "It's her fault because she was overweight or drank too much or didn't exercise enough." We would treat those employees with respect, try to accommodate their willingness to continue working, and would expect their fellow employees to demonstrate compassion and understanding. Like most responsible organizations, we do not see any legitimate reason to treat this disease any differently. It is your right to disagree with certain lifestyles. You may disapprove of the lifestyles of many of your co-workers and they may disapprove of yours. We are each entitled to our own point of view. However, in this organization, we think tolerance, cooperation, understanding, and compassion are useful human qualities. A fatal disease like AIDS provides an opportunity to demonstrate those qualities. 17 CHARTER UNDERSTANDING AIDS Despite all the bad news we are constantly hearing about AIDS, there is some promising news to report. Since AIDS was identified as a new medical condition in 1981, scientists have discovered important information about viruses and the function of the immune system. These biological facts concerning infectious diseases, the immune system, and AIDS have helped scientists reach certain conclusions about how the AIDS virus is and is not transmitted. The AIDS virus is the human immunodeficiency virus, or HIV. It can enter and infect certain HIV-the AIDS Virus cells, for example, the white blood cells that constitute the immune system, certain brain cells, and certain cells lining the lower bowel. As HIV infects and kills certain white blood cells essential to the normal function of the immune system, the immune system progressively loses its defensive capabilities. With the body's master defense system down, all sorts of microscopic bacteria, fungi, and viruses have a much better opportunity to cause disease. Certain cancers and infections, called opportunistic because they take advantage of the situation created by a suppressed immune system, plague people with AIDS and eventually lead to death. HIV-infected individuals who are symptomatic may suffer from a variety of HIV-related diseases and conditions which indicate that the immune system is impaired without having the specific opportunistic diseases associated with AIDS. (In the past, this condition was known as ARC, AIDS Related Complex.) 18 AIDS Education: A Business Guide The Transmission of AIDS Even under ideal laboratory conditions, HIV does not infect cells readily. It takes concentrated virus, or whole, live, infected white blood cells releasing virus to infect susceptible cells in the test tube. For transmission of HIV infection between people to be possible, exacting conditions must be realized. HIV-infected cells, carried in a chemically balanced, nutrient-rich liquid environment that sustains cell life, must be contributed by an infected person to an uninfected one. In addition, these infected cells must find their way into the body of the uninfected person. Saliva, sweat, urine, and tears are not life-sustaining fluids for cells. These are not fluids through which transmission of HIV occurs. Nor is transmission brought about by sneezing or coughing, nor even, as far is known today, by deep kissing. The fluids that do offer infected cells the environment needed for the transmission of this viral infection are blood, semen, vaginal fluids, and breast milk. The transmission of HIV can occur: during vaginal, anal, or oral intercourse, particularly when the uninfected partner has an open lesion in the mucosal membranes or the skin of the genital area; when unclean syringes or hypodermic needles contaminated with HIV- infected blood are used for injection; when blood from an HIV-infected mother passes to her child in the womb or at birth; when HIV-infected blood is inadvertently transfused into an uninfected person; in rare cases when the skin is accidentally punctured with a sharp object contaminated with HIV-infected blood. Both men and women can become infected through vaginal, anal, or oral intercourse. The specific circumstances under which HIV infection can be transmitted from person to person have been amply confirmed by detailed epidemiological studies. After several years of obser- vation, it has been shown that HIV infection has never been transmitted from one person to another unless infected semen, blood, vaginal secretions, or infected breast milk had been involved in its transmission. Understanding AIDS 19 That is why it can be said today with great confidence that there is no transmission of HIV under conditions of casual contact between people such as occurs in the workplace, in schools, and in public transportation systems; there is no transmission of HIV infection through food preparation, food handling, or food sharing. Barring blood transfer or sexual contact, there is no transmission of HIV among people living in the same household or from HIV-infected patients to doctors and nurses caring for them in hospitals, or from health care personnel to patients. Protecting Oneself and Others from AIDS There are few situations under which HIV infection can occur. Its spread in the population can be slowed by the adoption of the following: practicing sexual abstinence or maintaining a mutually monogamous sexual relationship with an uninfected person; decreasing risk of exposure to HIV by decreasing the number of one's sexual partners; preventing, through the proper and regular use of latex condoms and a spermicide, direct contact of semen with the vaginal or rectal mucosa (unless sexual partners positively know neither of them is infected); avoiding unprotected oral sex; using clean needles (whether new or thoroughly disinfected); preventing pregnancy in HIV-infected women; preventing the use of HIV-infected blood for transfusion, or of HIV-infected tissues or organs for transplantation. See also the section in this manual entitled "Common Questions and Answers About AIDS." Additional information on the immune system and AIDS can be found in the AmFAR publication "The Facts About AIDS". 21 Ц CHARTER INTEGRATION OF BENEFITS The key to effective care coverage is the integration of all the benefits so that, at any stage of the disease, people with HIV-related illnesses do not fall between the cracks of an other- wise well-designed health-care program. Case management that is carefully integrated into a total health care program has proven to The Case for Case Management be an effective method of dealing with AIDS as well as other high-cost illnesses. The term "case management" used here describes the use of a fourth party (a case manager) to analyze the psychosocial, legal, financial, housing, and clinical needs of an individual patient at high risk for catastrophic health care costs. Case management programs must emphasize the provision of high quality, medically appropriate services for all individuals using their health benefits. Employees should retain control over health care decisions and yet not lose coverage for treatment in situations where their treating physician, who is most familiar with their medical needs, recommends a manner of treatment different from that of the case manager. 22 AIDS Education: A Business Guide It is still not known how much long-term care will be needed for patients with HIV-related illnesses. For instance, the incidence of HIV-related mental impairment (dementia), which will likely require intensive treatment on a long-term basis, is increasing. In order to minimize costs of caring for patients with HIV-related illnesses, long-term disability administrators need to provide the same type of intensive case management as that provided under the medical plan. Informing Employees About Informing employees about the health benefits and company policy concerning HIV-infected Benefits and Policies individuals presents a communications challenge. Employers should expect this news to trigger a variety of responses. Many employees will see it as a sign that the company cares about their well-being. For others, however, it may provoke fear that there is a large AIDS problem in the company. Infected individuals may fear discrimination. Managers may feel unprepared to answer questions from employees. One common, effective strategy is to include AIDS and other HIV-related illnesses under existing policies on catastrophic illness. When this decision is made, no new definition of health benefits is necessary. If a company policy on catastrophic illness does not yet exist, the AIDS education program can be an optimum time to formulate a clear statement of the benefits and policy for employees who suffer from HIV-related illnesses and other major life threatening diseases. A well-planned communications effort can ensure that the policy on AIDS and other catastrophic illnesses is greeted positively and seen for what it is: practical and compassionate health care coverage. Presenting it in conjunction with a company's AIDS education program will promote its reception. Integration of Benefits 23 The following suggestions can help secure a positive reception: Garner support from the CEO, chairman of the board, or president of the company. If the business or company has a collective bargaining unit, solicit support from its leadership as well. A memo or letter by a recog- nized representative from top management and, where appropriate, union leadership, presenting the company's catastrophic illness policy demonstrates important support; Emphasize confidentiality and nondiscrimination; Alert, don't alarm, employees. Let employees know that the policy is addressing the special needs of individuals infected with HIV, as well as the needs of those who may suffer from other serious illnesses. Assure them that the program goes hand-in-hand with an education and prevention program and that the workplace is safe; Meet with managers first. If the business or company has a collective bargaining unit, include the union stewards as well. Give them time to prepare for questions that may arise from employees; Take advantage of Employee Assistance Program (EAP) resources. EAPs can play a key role in explaining health-related policies. The EAP is uniquely suited to provide counseling services. Confidentiality, critical in this situation, is a hallmark of an EAP. Companies can work directly with outside organizations or in-house staff to provide the necessary training to deal with AIDS and other diseases. The EAP staff can help diffuse or preempt potential problems associated with the presence of HIV-infected individuals in the workplace, as well as in management-employee relations. "AT&T's position on AIDS is to treat it as we would any other disabling condition and to emphasize that casual contact in the workplace is not a risk. An employee who has AIDS will be treated like those with any other illness. If not disabled, they will be permitted to work." Dorothea Johnson AT&T Corporate Vice President for Health Affairs 25 CHARTER 5 APPENDICES Resources A large number of resources are available to businesses to assist in formulating AIDS Education Programs and to make available accurate information about AIDS, HIV infection, and its transmission to employees. The following listing of resources may be used to obtain further information about AIDS. Initially, the best resource in your community may be the city, county or state Health Department Local Resources or a local chapter of the American Red Cross. These agencies can provide accurate information about AIDS, state, and local health policies, and HIV antibody testing sites. Most larger cities or geographical areas have AIDS service agencies which supply expert speakers, brochures, and posters, in addition to direct services to people with AIDS. Many of these agencies staff AIDS information hotlines. 26 AIDS Education: A Business Guide National Resources Service Directories The following directories provide comprehensive listings of educational and informational materials concerning HIV infection, HIV-related illnesses, and full-blown AIDS. They describe service organizations, brochures, pamphlets, videotapes, curricula, posters, books, manuals, government reports, and other resource documents on AIDS. AIDS Information Resources Directory Local AIDS Services National Directory American Foundation for AIDS Research United States Conference of Mayors (AmFAR) 1620 "I" St., NW 1515 Broadway, 36th Floor Washington, D.C. 20006 New York, NY 10036 202-293-7330 212-333-3118 Directory of AIDS Resources: AIDS Service Profiles - 1987-88 Directory A Guide to Sources of Information National AIDS Network (NAN) United Way of America 1012 14th St., NW, Suite 601 710 North Fairfax St. Washington, D.C. 20005 Alexandria, VA 22314-2045 202-347-0390 703-836-7100 Organizations and Information Sources AIDS National Interfaith Network Centers for Disease Control (CDC) 132 W. 31st St., 17th Floor Office of Public Inquiries New York, NY 10001 1600 Clifton Road, NW 212-239-8700 Building 1, Room B63 Atlanta, GA 30333 American Foundation for AIDS Research (AmFAR) 404-639-3534 1515 Broadway, 36th Floor New York, NY 10036 National Minority AIDS Council 212-333-3118 714 "G" Street, SE Washington, D.C. 20003 American Red Cross National Headquarters 202-544-1076 AIDS Education Program 17th and "D" Sts., NW National AIDS Network (NAN) Washington, D.C. 20006 1012 14th St., NW, Suite 601 202-639-3223 Washington, D.C. 20005 202-347-0390 Appendices 27 National Institutes of Health (NIH) U.S. Public Health Service (PHS) Building 1, Room 307 Public Affairs Office Bethesda, MD 20892 Hubert H. Humphrey Building 301-496-5787 Room 725-H For NIH Brochures and Publications: 200 Independence Ave., SW Washington, D.C. 20201 Building 31, Room 2B03 202-245-6867 301-496-4143 National Leadership Coalition on AIDS 1150 17th St., NW, Suite 202 Washington, D.C. 20036 202-429-0930 Unless your company has special needs, there is no reason to produce in-house educational Educational Materials brochures or videos. Currently, a variety of high-quality educational materials are available on the market. The following materials are provided as source material only. They are cited as typical educational material which is readily available. Produced by the U.S. Public Health Service, the Surgeon General's Report on Acquired Immune Deficiency Syndrome has received wide circulation, and Understanding AIDS was mailed to each household in the U.S. These brochures contain basic discussions of AIDS, how HIV is transmitted, the relative risks of transmission, and how to prevent AIDS. See page 8 for additional information. The following brochures are available from the American Red Cross (contact your local Red Brochures Cross Chapter for ordering information): AIDS and Your Job . Are There Risks? Informate de la que el SIDA A general AIDS introduction emphasizing the A general information Spanish-language safety of casual contact with people with AIDS brochure. or ARC. AIDS and the Safety of the Nation's Blood Supply AIDS: The Facts A discussion of the AIDS antibody test and its A general information brochure. use in screening the nation's blood supply. 28 AIDS Education: A Business Guide Other brochures available The Facts about AIDS and How Not to Get If Teens & AIDS: Playing it Safe A general information brochure. A brochure for teenagers about AIDS, absti- nence, and how to avoid the dangers of risky American Foundation for AIDS Research sexual practices. (AmFAR) 1515 Broadway, 36th Floor American Council of Life Insurance/Health New York, NY 10036 Insurance Association of America 212-333-3118 1001 Pennsylvania Avenue, NW Washington, D.C. 20004-2599 Asian Americans and AIDS (Equivalent titles in 202-624-2372 Japanese, Korean, Tagalog, Chinese, and Vietnamese) Multicultural Training Resource Center (MTRC) 1540 Market St., Suite 320 San Francisco, CA 94102 415-861-2142 Videotapes Videotapes are available for purchase, rental, or may be available for loan from your local American Red Cross Chapter or AIDS service agencies. A Letter from Brian Answers About AIDS A 25-minute video for use with teenagers. Features U.S. Surgeon General Koop giving an Parent, teacher/leader, and student materials overview of AIDS and frankly answering ques- included with the video. Produced by the Amer- tions from students in a classroom setting. ican Red Cross with funds from the American Council of Life Insurance and the Health American Red Cross, contact local chapter Insurance Association of America. Beyond Fear American Red Cross, contact local chapter A general discussion of AIDS in three segments: the virus, the individual, and the community. AIDS: Everything You and Your Family Need to Know, Available in twenty minute segments or a 30- But Were Afraid to Ask minute version. Produced by the American Red A general discussion of AIDS which first Cross with funds from the American Council appeared as an HBO special. Endorsed by the of Life Insurance and the Health Insurance American Foundation for AIDS Research Association of America. (AmFAR). Available in segments of different length. (16-minute to 1-hour) American Red Cross, contact local chapter Ambrose Home Video Publishing Don't Forget Sherrie Department 1087 Provides black and urban youth with information 381 Park Ave., Suite 1601 on reducing the risk of AIDS. New York, NY 10016 800-526-4663 American Red Cross, contact local chapter 212-696-4545 (NY) Appendices 29 Sex, Drugs, and AIDS The AIDS Movie A frank video which speaks to teenagers in their A story of three people with AIDS who share own language. Some sexually explicit language. the realities of the disease and how to protect Appropriate for teenagers and young adults. against it. San Francisco AIDS Foundation New Day Films 333 Valencia Street 22 Riverview Drive Fourth Floor Wayne, NJ 07470 San Francisco, CA 94103 201-633-0212 415-864-4376 A variety of multi-component programs, like the American Red Cross AIDS Prevention Program Multi-Component Programs for the Workplace (contact local chapter), are available from non-profit organizations and for- profit companies. See the AmFAR AIDS Information Resources Directory listed above (p. 26) for descriptions of these programs. Public Health Service AIDS Hotline National Sexually Transmitted Diseases Hotline Telephone Hotlines (Toll Free) 800-342-AIDS American Social Health Association 800-342-2437 800-227-8922 AIDS Information Hotline National Gay Task Force 800-221-7044 212-807-6016 (NY State) AIDS Data Where to Find AIDS Information Online Online Sources A comprehensive listing of online and periodical A description of online sources that provide AIDS information services. AIDS information. Reprinted from Online 1988 (March): 93-105. Contact Steve Clancy c/o Chris Hall or Rochelle Clary at: National AIDS Network (NAN) 1012 14th St., NW, Suite 601 University of California, Irvine Washington, D.C. 20005 P.O. Box 19556 202-347-0390 Irvine, CA 92713 714-856-7309 Computerized AIDS Information Network (CAIN) A consumer on-line data base with electronic communication capabilities. 1213 N. Highland Los Angeles, CA 90038 213-464-7400 30 AIDS Education: A Business Guide Sample Corporate Policies on AIDS American businesses have responded to AIDS in varying degrees and ways. Some companies have chosen to write new policies specifically for AIDS. Most companies have simply adapted existing catastrophic illness policies to include AIDS. Samples of existing company policies on AIDS can be obtained by writing or calling the American Foundation for AIDS Research (AmFAR) at the above (p. 26) address and phone number. State AIDS Prevention Program Project Additional information on AIDS can be obtained from the following state AIDS prevention Directors and Coordinators program Project Directors and Coordinators. ALASKA CALIFORNIA DISTRICT OF COLUMBIA Secretary of Epidemiology Office of AIDS Office of AIDS Activity AIDS Employee Education California Department of 1875 Connecticut Ave., NW Coordinator Health Services Suite 837 Division of Public Health P.O. Box 92732 Washington, DC 20009 P.O. Box 240249 Sacramento, CA 94234-7320 202-637-3679 Anchorage, AK 99524-0249 916-445-0553 DELAWARE 907-561-4406 AIDS Office Health and Social Services ALABAMA Department of Public Health Division of Public Health Department of Public Health 1111 Market St. AIDS Program Office State Office Building San Francisco, CA 94103 3000 Newport Gap Pike Room 657 415-864-5571 Bldg. G 434 Monroe St. Wilmington, DE 19808 Montgomery, AL 36130 Department of Health Services 302-995-8422 205-261-5017 AIDS Program Office 313 N. Figueroa St. FLORIDA ARKANSAS Room 1014 Health and Rehabilitation Department of Health Los Angeles, CA 90012 Services AIDS Prevention Program 213-974-7803 AIDS Program 4815 West Markham 1317 Winewood Blvd. Room 455 COLORADO Tallahassee FL 32301 Little Rock, AR 72205-3867 Department of Health 904-487-2478 501-661-2140 AIDS Education & Training/ STD Control Program GEORGIA ARIZONA 4210 E. 11th Ave. Office of Infectious Diseases Division of Disease Prevention Denver, CO 80220 AIDS Projects Office of Health Promotion 303-331-8320 Community Health Section and Education 878 Peachtree St., NE 3008 N. 3rd St., Room 103 CONNECTICUT Room 109 Phoenix, AZ 85012 AIDS Program Coordinator Atlanta, GA 30309 602-230-5819 Department of Health 404-894-5304 Services 150 Washington St. Hartford, CT 06106 203-566-1157 203-566-4800 (bulk orders) Appendices 31 HAWAII INDIANA MARYLAND MISSISSIPPI Department of Health AIDS Activity Office AIDS Administration Department of Health AIDS/STD Project State Board of Health Health and Mental Hygiene AIDS Prevention Program 1250 Punchbowl St. 1330 W. Michigan St. 201 West Preston St. P.O. Box 1700 Room 117 Indianapolis, IN 46206-1964 Baltimore, MD 21201 Jackson, MS 39215-1700 Honolulu, HI 96813 317-633-0851 301-225-5013 601-960-7728 808-548-4580 KANSAS MAINE MONTANA IOWA Bureau of Epidemiology, Office on AIDS Montana AIDS Prevention Department of Health AIDS Section Department of Human and Surveillance Program Division of Disease Kansas Department of Services Department of Health Prevention Health and Environment State House Section, # 11 Cogswell Building Lucas State Office Building Mills Bldg., Suite 605 Augusta, ME 04331 Helena, MT 59620 Des Moines, IA 50319 109 SW 9th St. 207-289-3747 406-444-2454 515-281-6438 Topeka, KS 66612 913-296-5588 MICHIGAN NEBRASKA IDAHO Special Office on AIDS Pre- AIDS Program Department of Health and KENTUCKY vention (SOAP) Department of Health Welfare Kentucky AIDS Project Center for Health Promotion 301 Centennial Mall South Bureau of Preventive Department of Health P.O. Box 30035 P.O. Box 95007 Medicine Services Lansing, MI 48909 Lincoln, NE 68509-5007 450 W. State St. 275 E. Main St. 517-335-8399 402-471-2937 Boise, ID 83720 Frankfort, KY 40621 208-334-5939 502-564-7112 MINNESOTA NORTH CAROLINA AIDS Prevention Services AIDS Control Program ILLINOIS LOUISIANA Section State of North Carolina AIDS Activities Section AIDS Project Division of Disease Department of Health Illinois Department of Public Office of Public Health Prevention P.O. Box 2091 Health Department of Health and Department of Health Raleigh, NC 27702 100 W. Randolph St. Hospitals 717 SE Delaware St. 919-733-3419 Suite 6-600 P.O. Box 60630 Minneapolis, MN 55440 Chicago, IL 60601 New Orleans, LA 70160 612-623-5698 NORTH DAKOTA 312-917-4846 504-568-5508 AIDS Project MISSOURI Department of Health AIDS Activity Office MASSACHUSETTS Department of Health State Capitol Building Chicago Department of AIDS Program Bureau of AIDS Prevention Bismarck, ND 58505 Health Massachusetts Department of P.O. Box 570 701-224-2378 50 W. Washington Public Health Jefferson City, MO 65102- Room 233 150 Tremont St. 0570 NEW HAMPSHIRE Chicago, IL 60602 Boston, MA 02111 314-751-6438 Division of Public Health 312-744-4312 617-727-0368 Services Bureau of Disease Control 6 Hazen Dr. Concord, NH 03301 603-271-4477 32 AIDS Education: A Business Guide NEW JERSEY OKLAHOMA SOUTH DAKOTA VIRGINIA Department of Health Department of Health Department of Health STD Control Section, AIDS AIDS Division AIDS Division AIDS Prevention and Program CN 360, 363 W. State St. P.O. Box 53551 Surveillance Project Madison Bldg. Trenton. NJ 08625 Oklahoma City, OK 73152 523 East Capitol 109 Governor St., Room 722 609-984-6000 405-271-4636 Pierre, SD 57501 Richmond, VA 23219 605-773-3364 804-275-4844 NEW MEXICO OREGON Health and Environment AIDS Coordinator TENNESSEE VIRGIN ISLANDS AIDS Prevention Program Department of Human AIDS Education Coordinator AIDS Surveillance and P.O. Box 968 Resources Department of Health and Prevention Santa Fe, NM 87504-0968 1400 SW 5th Ave., Room 710 Environment Department of Health 505-827-0086 Portland, OR 97201 100 9th Ave., N P.O. Box 1026 503-229-5792 Nashville, TN 37219-5405 Christiansted NEVADA 615-741-7387 St. Croix, Virgin Islands Division of Health PENNSYLVANIA 615-741-7500 00821-1026 STD Control AIDS Education Manager 800-525-AIDS (Tennessee 809-773-1059 505 E. King St. P.O. Box 90, Room 912 only) Room 200 Harrisburg, PA 17108 WASHINGTON Carson City, NV 89710 717-787-5900 TEXAS Division of Health 702-885-4800 Bureau of AIDS and STD Office on AIDS 800-842-AIDS (Nevada only) PUERTO RICO Control Mail Stop LP-20 STD Control Program Texas Department of Health Olympia, WA 98504 NEW YORK CITY Call Box STD 1100 W. 49th St. 206-753-3460 Department of Health Caparra Heights Station Austin, TX 78756 AIDS Program Services San Juan, PR 00922 512-458-7207 WEST VIRGINIA 125 Worth St., Room 222 809-754-8118, ext. 230 AIDS Program New York, NY 10013 utah 1800 Washington St., E 212-566-7103 RHODE ISLAND AIDS Control Program Charleston, WV 25305 Department of Health Bureau of Epidemiology 304-348-5358 NEW YORK STATE Disease Control Utah Department of Health Department of Health 75 Davis St., Room 105 288 N. 1460 West WISCONSIN AIDS Education and Training Providence, RI 02908 P.O. Box 16660 AIDS Program ESP Tower Bldg., Room 372 401-277-2362 Salt Lake City, UT 84116- Wisconsin Department of Albany, NY 12237 0700 Health 518-486-1320 SOUTH CAROLINA 801-538-6191 1 W. Wilson St. Health and Environmental Madison, WI 53702 OHIO Control VERMONT 608-267-9007 AIDS Activities Office AIDS Prevention Project Department of Health Department of Health STD Control Division STD Control Program WYOMING Epidemiology Division 2600 Bull St. P.O. Box 70 AIDS Health Education and 246 N. High St., 8th Floor Columbia, SC 29201 Burlington, VT 05401 Risk Reduction Program Columbus, OH 43266-0588 803-734-5482 802-863-7245 Preventive Medicine 614-466-5480 Hathaway Building, 4th Floor Cheyenne, WY 82002 307-777-5800 Appendices 33 Common Questions and Answers About AIDS Q Saliva, sweat and tears why can't the AIDS virus be transmitted that way? A This may be the most frequently-asked question about AIDS. Remember that for HIV (human immunodeficiency virus) to infect someone, it must get from inside an infected person's body to inside someone else's body, via fluid, to cause harm. Two research studies have indicated that HIV could sometimes be present in saliva or tears. These reports received a great deal of press attention. There have been no reports of anyone finding the virus in sweat. What did not get enough attention in the press were (1) in people who were known to be infected, the presence of the virus in saliva and tears was rare; Remember that (2) even when found, the virus was present in such small quantities and was SO heavily diluted, that it was unlikely to be of any risk to anyone. the virus is fragile outside the body. Remember that the virus is fragile outside the body. Even if the virus were present in a person's saliva or tears, and even if it managed to remain alive on the surface of something, it still cannot do any harm unless it is allowed inside someone's body. So, the odds are astronomically against it ever happening. Q Can mosquitoes transmit AIDS? A There have never been any cases of anyone getting HIV infection from mosquitoes. A mosquito only spreads germs that use the mosquito as part of the germ's life cycle. The malaria organism, for example, has to spend part of its life in an anopheles mosquito in order to mature, so mosquitoes can spread malaria. However, syphilis, hepatitis, and many other blood-borne infections such as HIV infection are not spread by biting insects. Mosquitoes don't go immediately from person to person. A mosquito will usually bite and feed about once every 48 hours. Even if the virus were there, it would be in incredibly tiny quantities and would die before the next bite. Also, if mosquitoes were transmitting HIV, we would see many more cases of AIDS in those parts of the country where mosquitoes are common. The answer is - No, mosquitoes do not transmit AIDS. Q What about swimming pools and hot tubs? A HIV infection cannot be spread via swimming pools or hot tubs. There are a number of reasons why swimming pools and hot tubs are safe. Remember that in order to do any harm, HIV-infected cells must get from inside the body of an infected person to inside the body of someone else and live cells must constantly be in a life-sustaining body fluid. 34 AIDS Education: A Business Guide If an infected person abundantly bled into pool water, virus and blood cells would be destroyed. Even if the pool were improperly chlorinated or not chlorinated at all, the virus could still not be transmitted. So, the virus doesn't really have a chance in a swimming pool or hut tub. Pools and hot tubs are safe. Q Why isn't the virus transmitted through food handling? A The basic principles of transmission apply here as well. To do any harm, the virus must be carried by live cells in a life-sustaining, fluid environment from inside the body of an infected person to inside the body of an uninfected person. No foods have the ability to keep cells alive, and live infected cells are rapidly destroyed in the stomach. The Centers for Disease Control says "all epidemiologic and laboratory evidence indicates that blood-borne and sexually-transmitted The Centers for Disease Control says, infections are not transmitted during the preparation of serving of "all epidemiologic laboratory evidence food or beverages... The CDC guidelines about AIDS in the indicates that blood-borne and sexually- workplace clearly state that "food service workers known to be infected (with the AIDS virus) need not be restricted from work transmitted infections are not transmitted unless they have evidence of other infection or illness for which during the preparation of serving of food any food service workers should also be restricted." or beverages. " Serving or eating utensils pose no risk. Soap and water kill cells. The kind of dishwashing equipment used in restaurants, company cafeterias or even home dishwashers rapidly and easily kill any cells and any amount of virus. Q Why should I trust medical authorities? They have been wrong before! A Because AIDS is such a highly-publicized and highly-politicized disease, the medical authorities have been more careful about this disease than any in history. Since 1981, regulations have required the reporting of every case of AIDS diagnosed anywhere in the United States to the Centers for Disease Control in Atlanta. Other studies have traced cases back nearly 10 years. Considerable expertise and expense have been devoted to learning about AIDS, particularly the way in which the disease might be transmitted from person to person. Each case of AIDS reported in the United States is carefully analyzed as to the possible methods by which the disease was acquired by that patient. Each patient is questioned about possible methods of exposure. Appendices 35 In addition, large group studies have been conducted over time with several thousand volunteer participants, some of whom have the disease, and others only the infection. Risk activities are documented and statistically correlated. These continuing studies are conducted by independent research groups in several different cities. The data collected by each group from thousands of participants is carefully analyzed and correlated with data from other studies. Several studies have also traced the health of doctors, nurses, and other health care workers in hospitals where AIDS patients are treated. Additional studies have carefully monitor- ed the health of children living in the same household with a child who has AIDS. Similar studies are conducted in Europe, Canada, Africa, and Australia. Scientists from these different areas exchange data and compare findings. The results of all of these separate investigations are striking in their consistency. Q What are the symptoms of HIV-related illnesses? A HIV disease cannot be diagnosed from symptoms alone. In fact, a person can be infected with HIV, but remain without symptoms for several years. However, there are several symptoms that, in combination or if present for an extended period of time, may suggest HIV disease, and are cause for checking with a physician. The symptoms of HIV-related illnesses are: unexplained, persistent fatigue (two or more months); unexplained fever, shaking chills, or drenching night sweats lasting longer than several weeks (recurrent or persistent over two or more months); unexplained weight loss of more than 15 pounds or 10% of body weight; swollen glands (enlarged lymph nodes usually in the neck, armpits or groin) which are otherwise unexplained and last more than two months; persistent white spots or unusual blemishes in the mouth; persistent diarrhea (two or more months), not explained after medical workup; pink to purple flat or raised blotches or bumps occurring on or under the skin, inside the mouth, nose, eyelids or rectum. Initially, they may resemble bruises but do not disappear. They are usually harder than the skin around them; persistent dry cough which has lasted too long (two or more months) to be caused by a common respiratory infection, especially if accompanied by shortness of breath. 36 AIDS Education: A Business Guide Please note that this list is very similar to the symptoms of other diseases. Some of them may be symptoms of stress. You cannot tell if someone has an HIV-related illness just by looking or just because that person has one or more of these symptoms. Only a doctor is capable of diagnosing an HIV-related illness, and he or she will need supporting laboratory tests to make that diagnosis. One or more of these symptoms for a prolonged period is a good reason to see a doctor. The symptoms might not mean HIV infection, but they may mean that some disease is operating in the body that could be serious unless properly treated. Q What about the AIDS antibody test? A "Antibodies" are substances that are produced by the immune system to help eliminate a specific foreign invader that can cause disease. The body produces specific antibodies for each specific invader. Production of antibodies is an essential element of the human immune response. The AIDS antibody test Polio antibody is designed to help attack and destroy the polio virus. detects the presence of those Measles antibody is designed to deal only with the measles. Viral HIV antibodies in a person's blood. antibody is produced by the body as a response to the presence of the AIDS virus. Each different antibody can be identified in the blood. It is not a test for AIDS. Unlike measles antibody, which can protect the body from measles, and unlike polio antibody, which can protect the body from polio, antibody to HIV does not appear to provide complete protection against the AIDS virus. However, since the body produces this antibody whenever it is infected with HIV, it can serve as a marker for and diagnosis of HIV infection. The HIV antibody test detects the presence of this antibody in a person's blood. It is not a test for AIDS, though it now appears that most of those who do test positive for the presence of this antibody will go on after a long incubation period to develop HIV- related illnesses or full-blown AIDS. The HIV antibody test has been used by blood banks since 1985 to screen out HIV- infected blood. However, since it may take the body's immune system up to three months on average to develop antibody to HIV, if an infected person donates blood during that three-month period, the blood may not test positive for AIDS antibodies. As a result, there is still a small risk of contracting HIV infection from receiving a blood transfusion. Physicians are well aware of this remaining small risk and now order transfusions only when absolutely necessary. Appendices 37 The blood test is also utilized by physicians to assist in diagnosing cases of HIV infection and full-blown AIDS. It is being used to screen military recruits, military service persons, applicants for immigrant status to the United States, and to assess risk of AIDS by some life and health insurance policies. A negative test result, as long as it is performed at least three months after any possible exposure to the virus, is a pretty good indicator that the person tested has never been infected by the virus. A positive test result, when verified by a confirmatory test, quite reliably indicates that the person has been infected with HIV. He or she should consult a physician regarding the medical implications of a positive test result. It is important that persons contemplating taking this test receive expert counseling before and also after the test, irrespective of test results. Regardless of one's test results, anyone who has not been in a mutually monogamous relationship for at least the last six years should take the necessary precautions to prevent contracting or transmitting HIV. Abstaining from sexual intercourse and intravenous drugs, or participating in a mutually monogamous relationship with an uninfected partner are the most effective ways to prevent Anyone who has not been in transmission of the virus. Otherwise, proper and regular use of latex condoms and a spermicide, and not sharing drug works a mutually monogamous relationship are the next best methods of reducing the risks of transmitting for at least the last six years should or contracting HIV infection. take the necessary precautions to prevent Q Can using a condom protect me from getting the AIDS virus? contracting or transmitting the virus. A Abstinence or sexual intercourse with one faithful uninfected partner are the only totally effective prevention strategies. Use of condoms with each act of sexual intercourse (vaginal, anal, or oral) can reduce, but do not completely eliminate, risk of infection with HIV and other sexually transmitted diseases. Latex condoms provide protection against HIV and other viral sexually transmitted diseases; membrane condoms do not. For condoms to be effective, they must be used properly. A condom and a water-based lubricant containing a spermicide must be used with each act of sexual intercourse. The condom must be put on and completely unrolled before any genital activity occurs. Oil- based lubricants weaken latex condoms and should not be used. Condoms are a way of reducing the risk of infection with HIV, but they are not a foolproof, completely safe method for avoiding infection. 38 AIDS Education: A Business Guide Q What about exposure to someone's blood? A Blood should be treated carefully, regardless of AIDS. Although intact skin is an effective barrier against HIV and blood-borne germs, they are common enough and serious enough so that blood should always be dealt with carefully. After contact with another person's blood, one should immediately wash one's hands thoroughly. An effective way to clean up quantities of spilled blood is by using an ordinary solution of regular household bleach - one part of bleach to ten parts of water, just as it says on the label. Products like Lysol or Tide can also be used. Use common sense about blood contact in the event of a serious accident. Minor amounts of blood, like the tiny bit of blood that can result from a minor paper cut or pin stick, are not a cause for concern. A common antiseptic or hand washing will remove any risk of HIV infection. Q Is it possible for someone to be a carrier of the AIDS virus and still look healthy? A There is no risk to you from Yes. You cannot tell by looking whether someone is carrying HIV in his or her system, nor would the individual know whether he working with a person who actually or she is carrying the virus. has AIDS or with someone who may If a person thinks he or she might be a carrier, it is a good idea be healthy but is carrying for that person to consider taking the HIV antibody test. It would the virus. be especially important for a woman contemplating pregnancy to take the test if either she or the prospective father might possibly have been exposed to the virus. As far as the workplace is concerned, it does not matter whether one is a carrier or not, since there is no risk to anyone from working with a person who actually has AIDS or with someone who may be healthy but is carrying the virus. Q Why is it safe to donate blood? A Some people have the mistaken impression that donating blood is risky. This is not true because people who donate blood cannot be exposed to anything. Blood donors are provided with a sterile, throw-away needle that is used only once. Nothing enters the donor's body that can do any harm. There is no way for any virus to enter the donor's blood-stream when donating blood at a blood bank. Before the blood screening programs were instituted in the nation's blood banks in 1985, some people were exposed to HIV through receiving transfusions of someone else's contaminated blood. With the implementation of the blood screening program, the risk of getting HIV infection and AIDS from a blood transfusion has decreased substantially. Appendices 39 The blood banks always need blood. Unless you have some reason to think that you might already be infected with HIV, please help out by donating blood at your local blood bank or blood drive. There is absolutely no risk in donating blood. Q If, as you say, the medical evidence is so definite and this disease isn't a danger to us, why is AIDS still such a big deal? Parents are picketing schools, people with AIDS are being fired, the military is testing everyone, and laws are being proposed to bar people from food-handling jobs. A AIDS raises a lot of fundamental, serious, and very sensitive questions and issues that have nothing to do with disease or medicine - questions and issues about which many people have extremely strong and very vocal opinions. AIDS also has many elements that make it a sensational topic for the press: sex, drugs, blood, death. We can expect that AIDS will remain Much of the excitement about AIDS doesn't really relate to the disease or to HIV itself. It relates to strongly-held beliefs and a controversial disease for some time, opinions about the behaviors that are often responsible for so long as it remains connected with our transmitting the virus, and about those people who SO far most beliefs and traditions and differing often have been diagnosed with AIDS. points of view about morality. AIDS is a relatively new disease for most people. Since there is no cure, it's scary. We're all afraid of something we aren't used to and that we don't fully understand. And, of course, parents are even more concerned about a new disease where their young children are concerned. They are often not willing to listen to the evidence unless someone will give them an ironclad guarantee that there is absolutely no possible risk under any circumstances. No one is going to give them ironclad guarantees about any aspect of their child's safety and well-being away from the home. Neither can the parents absolutely guarantee the safety and well-being of the child even when the child is at home. We can expect that AIDS will remain a controversial topic for some time, SO long as it remains connected with our beliefs and traditions and differing points of view about morality. We each have our own deeply-held beliefs on such matters and we are each entitled to those beliefs. But if we are to be responsible about this disease, we must not let the more emotional issues - however valid and important they may be to us - cloud our understanding of the medical facts about the disease and about the way it is spread. Whatever our feelings about how HIV infection is spread, we are still left with the fact that AIDS is not spread in the workplace. 40 AIDS Education: A Business Guide Q Who gets AIDS? A People who have died of AIDS in the United States have been male and female, young and old, rich and poor, white, black, Hispanic, Asian, and American Indian. The male homosexual population was the first in this country to feel the effects of the disease. A significant number of intravenous drug users were also infected. Today members of these two groups constitute the largest number of AIDS cases. The remaining categories include hemophiliacs, transfusion recipients, and heterosexuals and their infants (transmission can occur from an infected female to an uninfected male, or from an infected male to an uninfected female). It is clear that anyone can get AIDS. Engaging in high risk behavior like having unprotected sex (oral, vaginal, or anal intercourse) or using intravenous drugs is a far more significant index of who will become infected with HIV than where one lives or what one's sexual orientation is. a What happens when a person becomes infected with the AIDS virus? If is clear that A It is not known exactly how many of those infected with HIV will anyone can get AIDS. actually develop AIDS, but it is now believed that most of them will, in the long run, develop symptoms. (In the past, this condition was known as ARC, AIDS Related Complex.) Among them, a substantial number will develop full-blown AIDS, with symptoms of specific life-threatening diseases such as pneumocystis carinii pneumonia (PCP) or Kaposi's sarcoma (KS). It can take anywhere from a few months to several years or more after HIV infection for HIV-related diseases to develop. It is difficult to generalize how serious the disease will be at any point. Some people with symptoms of HIV infection or even full-blown AIDS can have long periods of good health alternating with periods of illness. Some die very quickly; most remain generally healthy and very active for extended periods. Each case may be quite different. Q - Can AIDS be treated or cured? A There is so far no treatment that will destroy HIV in the human body or that will restore the immune system. Research on antiviral and immunorestorative drugs is under way in the United States and other countries. In many patients, the drug AZT retards viral multiplication and, as a result, reduces the risk of complicating infections and prolongs life. Appendices 41 People with AIDS, however, are often successfully treated for specific opportunistic infections and may lead active lives for long periods of time. People with AIDS, like people with other life-threatening illnesses such as cancer or heart disease, may need extra social and emotional support. Researchers are not optimistic about the development of any effective vaccine or cure for AIDS in the immediate future. A cure would require a two-fold solution: a way to stop the virus from doing any further damage in the body and a way to restore the damage that has been done. Just as we do not yet have a literal "cure" for many cancers, even after decades of research, a true cure for AIDS may remain elusive for a long time but it is reasonable to expect that progression from HIV infection to full-blown AIDS will be slowed or stopped in the foreseeable future by treatments presently in experimental studies. However, AIDS is preventable and is not easily spread. Education is currently our best preventive measure. Q If AIDS is a venereal disease, why isn't it curable like other People with AIDS are often successfully venereal diseases? treated for specific infections and may lead A Not all veneral diseases are curable even today; most were active lives for long periods of time. not curable until antibiotics became available in the 1940's. Veneral diseases are now referred to as "sexually transmitted diseases." They have been a problem for centuries. Gonorrhea and syphilis were epidemic diseases in many countries as late as the 20th century. These diseases were incurable, painful, disfiguring, and often led to death. Syphilis was especially dangerous, usually leading to insanity and death. Many famous people had the disease. Beethoven and Mozart are said to have died from syphilis. Winston Churchill's father died of syphilis. Syphilis wasn't consistently curable until 1944. Herpes, a sexually transmitted disease caused by a virus, is still incurable. A few years ago, the press gave a great deal of attention to the epidemic of herpes infection. Little is written about it today, even though there are more new cases of herpes diagnosed today than there were then. The press and the public simply lost interest in the topic. HIV infection may be curable someday, but as with many other diseases, the development of a cure will take time. Q I thought science had solved the problem of epidemics. Why are we having an epidemic now? A Epidemics of infectious diseases have come along every few generations since the beginning of recorded history. Even as one epidemic ended, people always knew that another one 42 AIDS Education: A Business Guide would eventually come along. Our generation, however, thought that we had developed the medical technology that would make epidemics a thing of the past. We were wrong. All living things on Earth, including viruses and bacteria, constantly undergo genetic mutations. Some result in organisms that are unusually harmful to humans. When that happens, an epidemic may erupt. In 1918 and 1919, an epidemic of influenza killed 400,000 Americans in a single year, and millions of people worldwide. That virus mutated itself out of existence. In this country, an epidemic of polio lasted from the 1930s until well into the 1950s, when a vaccine for polio was finally developed. General immunization stopped the epidemic. There have been periodic outbreaks of bubonic plague in this country, even into this century. Thanks to antibodies against the bacterium that causes it, this disease is not frightening anymore. Epidemics may always We tend to take a short view of history sometimes, and tend to exaggerate be a periodic part our faith in technology. Science may eventually solve the problem of AIDS. of human existence. But we should be prepared for some other mysterious disease to come along in the future, which will take time for technology to eliminate. This is a strong argument for continuing the support of biomedical research programs. Epidemics may always be a periodic part of human existence. Q I don't care what you say about AIDS not being a risk at work. I don't want to work with a person who is carrying that virus. What are you going to do for me and my concerns? A Well, suppose that someone was afraid of working with YOU for some reason that had no medical, scientific, or logical basis. We would certainly talk with the person, explain that their fears of working with you were unfounded, offer some counseling if necessary, and try to work it out. a I have some questions about AIDS that I don't want to discuss here today. Where can I get some confidential information? A Talk with your doctor. If your doctor isn't yet familiar with AIDS, ask him or her to become educated about AIDS so he or she can answer your questions. Don't be surprised if your physician is not familiar with AIDS. It is a new specialty for many doctors. (Note: Some employees may find it difficult to talk to a family doctor. Make sure your business or company provides other resources for an employee to get additional or personal information about AIDS. Please indicate how they are available to employees. Also, the Resources section of this manual provides a variety of AIDS hotline phone numbers.) Appendices 43 Centers for Disease Control Guidelines on AIDS in the Workplace Summary of Centers for Disease Control Guidelines on AIDS in the Workplace, November 1985 The CDC has issued recommendations to provide employers with guidance on the health risks of employing a person with AIDS: 1 The basic recommendation is that an employee with AIDS need not be restricted from work in any area unless they have evidence of other infections or illnesses for which any employee in that area of work should also be restricted. 2 Where blood or other body fluids are present, make use of the following personal protective equipment: Use gloves where blood, blood products, or body fluids will be handled; Use gowns, masks, and eye protectors for procedures that could involve more extensive splashing of blood or body fluids; Use pocket masks, resuscitation bags, or other ventilation devices to resuscitate a patient to minimize exposure that may occur during emergency mouth-to-mouth resuscitation. Employers should place these devices where the need for resuscitation is likely. The following workplace practices should be observed: Wash hands thoroughly after removing gloves, and immediately after contact with blood or body fluids; Use disposable needles and syringes whenever possible. Do not recap, bend, or cut needles. Instruments that penetrate the skin, e.g., tattooing and acupuncture needles or ear-piercing devices, should be used once and disposed of or be thoroughly cleaned and sterilized. Instruments not intended to penetrate the skin, but which may become contaminated with blood (e.g. razors) should be used for only one client and disposed of, or thoroughly cleaned and disinfected. Place sharp instruments in a specially-designated, puncture-resistant container located as close as practical to the area where they are used. Handle and dispose of them with extraordinary care to prevent accidental injury. Follow general guidelines for sterilization, disinfection, housekeeping, and waste disposal. Use appropriate protective equipment. Place potentially infective waste in impervious bags and dispose of them as local regulations require. 44 AIDS Education: A Business Guide Clean up blood spills immediately with detergent and water. Use a solution of 5.25 percent sodium hypochlorite (household bleach) diluted between 1-10 and 1-100 parts water for disinfection. No special precautions are required for personal service workers whose services do not involve a risk of blood contamination. 3 The CDC does not recommend a prohibition on employment of a person with AIDS working in food services. No evidence exists of transmission of either HIV or hepatitis B virus during the preparation or serving of food or beverages. 4 Workers with AIDS in a setting such as an office, school, factory or construction site have no known risk of transmitting the infection to co-workers, clients or consumers. 5 The CDC finds the greatest risk of transmission of HIV in the health-care workplace, especially those health-care workers who take part in invasive procedures, such as surgery. It is the CDC's position that even health-care workers who are known to be infected with HIV, but who do not perform invasive procedures, "need not be restricted from work unless they have evidence of other infection or illness for which any (health-care worker) should be restricted." OSHA Enforcement Various OSHA standards apply to exposure to the hazards of potential infection of both the HIV and hepatitis B viruses. These standards cover personal protective equipment, sanitation, and waste disposal. In addition, the General Duty Clause of the OSHA Act requires employers to provide "employment and a place of employment which are free from recognized hazards. Employers must comply with either the federal OSHA standards and the General Duty Clause or with state standards. States with approved plans to operate their own occupational safety and health program enforce standards comparable to the federal standards and are encouraged to enforce state counterparts to the General Duty Clause. State plan standards, unlike federal standards, apply to state, county, and municipal workers as well as to private employers. Workers whose employers will not correct hazardous situations may complain to federal OSHA or to the appropriate state OSHA in states that operate their own OSHA programs. Complainants' identities will not be revealed to employers. OSHA also investigates employee complaints of discriminatory actions by employers against employees who have exercised safety and health rights. For more information on OSHA inspection and compliance contact the OSHA office of Health Compliance and Assistance (202-523-8036). NOTES NOTES NOTES Underwritten by: Drexel Burnham Lambert AT&T Pacific Mutual American Council of Life Insurance Health Insurance Association of America FY.I. too HILL AND KNOWLTON here chriss Good / foit but this does may confirmenen 1 conor. our Ed McNally Hill and Knowlton Public Affairs Worldwide Co. Washington Harbour 901 31st Street, N.W. Washington, D.C. 20007-3838 202-333-7400 Telecopy 202-333-1638 Telex 440143 HKDC much line about to a a cure for E. March 6, 1990 just received this The Honorable lead David F. Demarest, Jr. Assistant to The President doday (3/26/90) for Communications The White House Washington, D.C. 20500 Dear Dave: Enclosed is the material I mentioned during our telephone conversation. As we discussed, an important message which the American people need to hear is that money currently being spent on AIDS research will have a lasting impact on diseases other than HIV. The new doors being opened and new tools being discovered via current research will be of untold benefit to future generations in every segment of American society. As I mentioned, we are closely working with Dr. Mathilde Krim of AMFAR (American Foundation for Aids Research), Dr. Samuel Broder, Director of the Cancer Research Institute at the National Instititues of Health and Dr. Robert Gallo, Chief of the Laboratory of Tumor Cell Biology at NIH. I do hope Dr. Krim's letter provides "fodder" for the speechwriters as they prepare The President's remarks for the National Leadership Coalition on AIDS scheduled for March 29th. Sincerely, Daine Elaine D. Crispen Senior Vice President 1515 BROADWAY SUITE 3601 AMFAR NEW YORK. NY 10036-8901 (212) 19-0033 R FAX: 212) 719-0712 BOARD OF DIRECTORS National Chairman Elizabeth Taylor March 23, 1990 Chairman of the Board loei Weisman. D.O Founding Co-Chairs Michael S. Gottlieb. M.D. Mathilde Krim. Ph.D. Mr. James Jennings President Mervyn F. Silverman. M.D. M.P H. HILL & KNOWLTON In Memoriam 901 31stStreet, N.W. Sheldon Andelson. Esq. Peter Scott. Esq. Washington, D.C. 20007-3838 Directors Arthur I. Ammann. M.D. Burr Bacharach Jonathan Canno Peter F. Carpenter Dear Jim: Kenneth Cole Mrs. Michael Eisner Susie Field Harvey Fineberg. M.D., Ph. D. Following our conversation, I have taken the Michael Fuchs David Geffen liberty of forwarding some language that William Haseltine. Ph.D. addresses the issue of how AIDS research can Arnold Klein. M.D. Mrs John W. Kluge affect all Americans: Barry Krost Philip Lee. M.D. Philip B. Miller Woodrow A. Myers. Jr.. M.D. M.B.A. Dollars spent for AIDS research are dollars Rev. Randolph Nugent Carole Bayer Sager spent for the better health of all Wallace Sheft. C.P.A. The Rt. Rev. William E. Swing Americans. Even more than the technologies Rosemary Tomich Abigail Van Buren developed by the space program, the benefits Mrs. Lew Wasserman of bio-medical science moving forward will Director Emeritus Mrs. Albert D. Lasker touch all of us in decisive ways. NATIONAL COUNCIL Woody Allen Warren Beatty AIDS research is broad-based biological Leonard Bernstein Barry Bostwick research. It includes research on a class Benjamin J. Buttenwieser. Esq. Joseph A. Califano. Jr.. Esq. of viruses now increasingly believed to be Rosalynn Carter Leo Castelli the cause not only of AIDS, but of several Sammy Davis. Jr. currently incurable chronic degenerative or Phil Donahue Douglas Fairbanks. Jr. malignant diseases such as muscular Morgan Fairchild Harvey Fierstein dystrophy, multiple sclerosis and at least Lawrence Fouraker. Ph.D. Georgia Frontiere two forms of leukemia. Katharine Graham Robert D. Haas George Hamilton Ashton Hawkins. Esq. AIDS research also concerns itself with the Marilyn Home Mrs. Lyndon Baines Johnson functioning of the immune system: it is Arthur B. Krim. Esq. Helen Kushnick clarifying the role played by this system in Angela Lansbury fighting viruses, microbes and cancer cells Marguerite Littman Greg Louganis and we will learn, through AIDS research, The Rt. Rev. Paul. Moore. Jr. Tony Randall how to restore failing immune defenses. Robert Rauschenberg Jonas Salk, M.D. Nothing could have more relevance to a wide Liz Smith Michael I. Sovern. Esq. array of conditions, from common infections Barbra Streisand Jack Valenti and cancers to potentially life-saving organ Raquel Welch and bone marrow transplantations. LOS ANGELES OFFICE 5900 WILSHIRE BOULEVARD SECOND FLOOR. EAST SATELLITE AIDS research also addresses the prevention LOS ANGELES. CA 90036-5032 (213) 857-5900 and treatment of the devastating infections FAX: (213) 857-5920 and cancers that are common -- and often fatal -- complications in people with AIDS as well as in all those with a weakened FOR AIDSR Mr. James Jennings Page 2. March 23, 1990 immune defense system, such as debilitated old people and infants. For them, AIDS research has already produced methods for the effective treatment of shingles and the prevention of a deadly form of pneumonia. Similarly, AIDS research has lead to the discovery of two new drugs for the treatment of herpetic infections, including those infections that lead to serious birth defects or blindness. Many other new drugs to combat viruses are now in development because the pharmaceutical industry is responding to the challenge of AIDS. AIDS research has also spurred the application of modern molecular technologies to the development of vaccines and even the use of cellular and genetic engineering for therapy. The intensive research effort developed to combat AIDS is opening vast new frontiers in disease prevention and treatment. It is making real today what was thought impossible only a few years ago. James Mason, M.D., Assistant Secretary for Health, Department of Health and Human Services, has said that the fruits of research in one area cross over into others. "The breakthroughs in AIDS largely have come because of work that was done in cancer research, and the research that is being done in AIDS will benefit us" in other areas. "In other words, biomedical research is never SO targeted." Knowledge about damage of immunological functions from AIDS will be applicable to "cancer and a whole series of other diseases,' Mason asserted. This last paragraph quoting Dr. Mason is taken from the FDC Reports, Inc., March 19, 1990, p. 6. I hope this information is useful. Please call me if I may be of any further help. Mathilde Krim, Ph. D. Founding Co-Chair MK/hb HUMAN HEALTH DEPARTMENT OF HEALTH & HUMAN SERVICES Public Health Service OF DEPARTMENT National Institutes of Health National Cancer Institute Bethesda, Maryland 20892 Building 37 Room 6A09 Tel: (301) 496-6007 Fax: (301) 496-8394 March 26, 1990 Mr. James Jennings Hill and Knowlton Public Affairs Worldwide Co. 901 31st Street, N.W. Washington, D.C. 20007-3838 Dear Jim: In response to your inquiry about how AIDS touches all of us, please consider the following points which I have limited to the broad medical implications of AIDS research. Obviously, the economic, social, moral, and global-political implications are even wider. It is true that most of the major advances in AIDS research came out of basic cancer research. Conversely, one can easily imagine that out of AIDS research will come major advances in several other areas of medical research, even more so than any other area of research. Let me illustrate with some specific examples. 1. Cancer. It should not be forgotten that AIDS is very frequently associated with the development of some cancers. Two are particularly common: B-cell lymphomas (a cancer of the lymph glands) and Kaposi's sarcoma. In fact, in association with infection with the AIDS virus, these have become the fastest increasing cancers. What is important is that from AIDS research new information on the mechanisms of how these tumors develop has already become available. I predict that within 1990-91 new treatments for these cancers will also come directly from AIDS research. 2. Basic understanding of the immune system. AIDS is primarily a failure of a central cell of the immune system. Other than direct studies on the AIDS virus, basic research in AIDS is basic research of our immune system. The immune system is at the heart of many human health problems from infectious disease to aging and cancer. Out of AIDS research new understanding of the function of immune cells has already occurred. Ltr, Mr. Jennings, 3/26/90, Page 2 3. The cause of AIDS is a special kind of virus called a retrovirus. The AIDS virus has two cousins which also cause serious diseases in man, including two forms of leukemia and neurological diseases similar to multiple sclerosis. Thus, the studies of these kinds of viruses in general will have spin- offs to an understanding of these problems. 4. Basic molecular biology, i.e., basic mechanisms within the cell. Unexpectedly, out of AIDS research has come mechanisms and insights into some areas of the molecular biology of the cell which are novel. 5. New drugs for infectious diseases. Patients with AIDS develop an incredible number and type of infectious diseases. This has spawned areas of research which have led to new and improved treatment of some of these infectious diseases. 6. Anti-viral chemicals. Before AIDS there were almost no chemicals against a virus and too little research in the whole area. Viruses, of course, unlike bacteria are not killed by antibiotics but require more subtle approaches to control. The AZT story is a story of pioneering research not just for AIDS but for the history of anti-viral agents. 7. Vaccines. No AIDS vaccine exists as yet. No vaccine has ever been successful against a virus which shows considerable variation. (Influenza is sort of an exception but its variation is not at the magnitude of the AIDS virus and the vaccine is not always successful.) The point here is that if a successful AIDS vaccine is made it will mean this kind of problem (the virus variation problem) will have been solved. This will have immediate impact for infectious diseases in general and viral diseases in particular. I close by reminding you that if we (Americans) solve this problem it will be one of the greatest things we could do for the world and for our own self esteem. Sincerely yours, Bor Robert C. Gallo, M.D. RCG: am HILL AND KNOWLTON Hill and Knowlton Public Affairs Worldwide Co. Washington Harbour 901 31st Street, N.W. Washington, D.C. 20007-3838 202-333-7400 Telecopy 202-333-1638 Telex 440143 HKDC March 27, 1990 The Honorable David F. Demarest, Jr. Assistant to The President for Communications The White House Washington, D.C. 20500 Dear Dave: Attached is some additional information which might be helpful to The President for his remarks this Thursday before the National Leadership Coalition on AIDS. I realize the speech has already been tasked and know how difficult last-minute material is to deal with, but I wanted you to have this critical information to see if it could be worked into the text. Being experts in the field, I didn't want the material from Dr. Krim and Dr. Gallo to go unheeded. Again, many thanks for your attention to this matter. Sincerely, Elaine D. Crispen Senior Vice President Attachments