Ask the Scholar
Page 21 of 24
I can add historical knowledge about this page.
Page image
OCR
I7.
Viol in his work on excretion found that 35 to 40 per cent of the radium injected in-
travenously was excreted in ten days and there after the excretion rate was around I per
sentp per month He based his observations on an examination of the excreta. Wada in-
jected 25 and I000 M U doses of radium into a series of rabbits and at the end of
four mnoths he wag unable to detect any radium in the organs of the rabbit getting the
25 M U dose. - the case of the IOOO M U he found radium in the bones and the
amount
found bore a relationship to the amount injected. He has made an interesting observation
that may have aome bearing on our problem. He feels that in order to get a stimulating
effect it is better to inject a large quantity at once as the part not eliminated at
the begimning is stored in the bones and thus furmishes the blood with a steady stream
of emanations. On the other hand small doses given repeatedly act# on all the cella of
the body and among them the blood forming cella and this repeated stimulation is ob-
viously too strong.
Our experiments bear out Viol to a certain extent. We injected an equal amonut Of
radium into a number of piga and killed them off at stated periods, burming them to an
ash and making a radium deternimation. This XEPE experiment is still being contimued
and will be reported at an early date.
Some of our findings are:
Amimal killed I5 minutes after injestion
4.21 micro grams
24 hours
3.73
48 2
3.15
7 days
I.32
I4
"
I.29
Gudzent states that quantities of .00I mg of radium equivalent increases the vital
functions while amoumts of .25 imhibit them. Both he and Beck feol that the effects are
not due to the radium itself but to the emanations. Beck discusses a toxema the re-
Altri brought don't by
sult of the by-products which result from their actions on the cellular structure. Due
to the iomizing action of radium probably many of its effects physical chemical changes.
The observations by Chamber and Russ indicate that the red cell: of the human blood
are hemolyzed much more sasily by the alpha rays than by the beta and gamma rays.
Page data
- Page
- 21
- Source index
- 0
- Type
- photo
- Media ID
- e37f00f99c38317f
- Size
- unknown
Document data
- ID
- 75720556
- Core
- doc
- Type
- document
DTO data
{
"id": "75720556",
"sourceUrl": "https://catalog.archives.gov/id/75720556",
"contentType": "document",
"title": "Report to [A. Roeder], January 28, 1926",
"citationUrl": "https://catalog.archives.gov/id/75720556",
"collections": [
"Safety Light Collection",
"Records Related to Radium Dial Painters"
],
"iiifBase": "https://s3.amazonaws.com/NARAprodstorage/lz/electronic-records/SLC/Radium/SLC_0000695_Page_01.jpg",
"thumbnailUrl": "https://s3.amazonaws.com/NARAprodstorage/lz/electronic-records/SLC/Radium/SLC_0000695_Page_01.jpg",
"largeImageUrl": "https://s3.amazonaws.com/NARAprodstorage/lz/electronic-records/SLC/Radium/SLC_0000695_Page_01.jpg",
"imageCount": 24,
"hasImages": true,
"source": "import",
"hasTranscription": false
}
Context sent to Scholar
Document identity
{
"localId": "75720556",
"label": "Report to [A. Roeder], January 28, 1926",
"core": "doc",
"dtoType": "document",
"citationUrl": "https://catalog.archives.gov/id/75720556"
}
Document source metadata
{
"id": "75720556",
"sourceUrl": "https://catalog.archives.gov/id/75720556",
"contentType": "document",
"title": "Report to [A. Roeder], January 28, 1926",
"citationUrl": "https://catalog.archives.gov/id/75720556",
"collections": [
"Safety Light Collection",
"Records Related to Radium Dial Painters"
],
"iiifBase": "https://s3.amazonaws.com/NARAprodstorage/lz/electronic-records/SLC/Radium/SLC_0000695_Page_01.jpg",
"thumbnailUrl": "https://s3.amazonaws.com/NARAprodstorage/lz/electronic-records/SLC/Radium/SLC_0000695_Page_01.jpg",
"largeImageUrl": "https://s3.amazonaws.com/NARAprodstorage/lz/electronic-records/SLC/Radium/SLC_0000695_Page_01.jpg",
"imageCount": 24,
"hasImages": true,
"source": "import",
"hasTranscription": false
}
Document source extras
{
"url": "https://catalog.archives.gov/id/75720556",
"naId": 75720556,
"levelOfDescription": "fileUnit",
"recordType": "description",
"ocrSource": "nara-archive"
}
Page context
{
"seq": 21,
"pageIndex": 0,
"type": "photo",
"url": "https://s3.amazonaws.com/NARAprodstorage/lz/electronic-records/SLC/Radium/SLC_0000695_Page_21.jpg",
"mediaId": "e37f00f99c38317f",
"ocrText": "I7.\nViol in his work on excretion found that 35 to 40 per cent of the radium injected in-\ntravenously was excreted in ten days and there after the excretion rate was around I per\nsentp per month He based his observations on an examination of the excreta. Wada in-\njected 25 and I000 M U doses of radium into a series of rabbits and at the end of\nfour mnoths he wag unable to detect any radium in the organs of the rabbit getting the\n25 M U dose. - the case of the IOOO M U he found radium in the bones and the\namount\nfound bore a relationship to the amount injected. He has made an interesting observation\nthat may have aome bearing on our problem. He feels that in order to get a stimulating\neffect it is better to inject a large quantity at once as the part not eliminated at\nthe begimning is stored in the bones and thus furmishes the blood with a steady stream\nof emanations. On the other hand small doses given repeatedly act# on all the cella of\nthe body and among them the blood forming cella and this repeated stimulation is ob-\nviously too strong.\nOur experiments bear out Viol to a certain extent. We injected an equal amonut Of\nradium into a number of piga and killed them off at stated periods, burming them to an\nash and making a radium deternimation. This XEPE experiment is still being contimued\nand will be reported at an early date.\nSome of our findings are:\nAmimal killed I5 minutes after injestion\n4.21 micro grams\n24 hours\n3.73\n48 2\n3.15\n7 days\nI.32\nI4\n\"\nI.29\nGudzent states that quantities of .00I mg of radium equivalent increases the vital\nfunctions while amoumts of .25 imhibit them. Both he and Beck feol that the effects are\nnot due to the radium itself but to the emanations. Beck discusses a toxema the re-\nAltri brought don't by\nsult of the by-products which result from their actions on the cellular structure. Due\nto the iomizing action of radium probably many of its effects physical chemical changes.\nThe observations by Chamber and Russ indicate that the red cell: of the human blood\nare hemolyzed much more sasily by the alpha rays than by the beta and gamma rays."
}