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WILLIAM L. CLARK, M.D.
2215 Walnut Street,
Phila., Pa.
April 14,1926.
Dr. Frederick B. Flinn,
Professor Industrial Hygiene,
New York City. N.J.
Dear Doctor Flinn:
I returned a few days ago after spending the winter in
Florida convalescing from illness. I did not take care of correspondence while
there which accounts for my failure to reply to your letter dated January 26th.
Replying to your question regarding the character of bone ne-
crosis following the use of radium salts and emanation. I have not observed
that this necrosis differs materially from that following the use of any other
agent that would cause bone disintegration. I especially speak of caustics,
and high frequency currents, and such diseases as Amberculosis or lues. Radium
necrosis of bone may not occur for a period of months, or even years, after
exposure to radium. Hence the necessity of using great care in its application.
Perosity is first noted, gradually developing into complete disintegration and
sequestration. This phenomenon has been determined by x-ray studies.
The dentist with whom you conferred is probably right in his
observations, but I believe that the gelantinous nature of the bone was. caused
by bacterial invasion and continued maceration by secretions in the mouth.
We are constantly removing disintegrated bone in patients that have been treated
by radium, which condition is entirely independent of carcinoma, and was
caused entirely by radium.
If there is any way that I can assist you in yor studies please
call upon me. I regret that conditions were such that I could not report to you
before.
With kind regards, I am
Sincerely yours,
(signed) W.L. Clark.
P.S. I have directed that a reprint on objections to Radium Emanation in
bare Tubes be sent you, from which you may glean some information.
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"ocrText": "COPY\nWILLIAM L. CLARK, M.D.\n2215 Walnut Street,\nPhila., Pa.\nApril 14,1926.\nDr. Frederick B. Flinn,\nProfessor Industrial Hygiene,\nNew York City. N.J.\nDear Doctor Flinn:\nI returned a few days ago after spending the winter in\nFlorida convalescing from illness. I did not take care of correspondence while\nthere which accounts for my failure to reply to your letter dated January 26th.\nReplying to your question regarding the character of bone ne-\ncrosis following the use of radium salts and emanation. I have not observed\nthat this necrosis differs materially from that following the use of any other\nagent that would cause bone disintegration. I especially speak of caustics,\nand high frequency currents, and such diseases as Amberculosis or lues. Radium\nnecrosis of bone may not occur for a period of months, or even years, after\nexposure to radium. Hence the necessity of using great care in its application.\nPerosity is first noted, gradually developing into complete disintegration and\nsequestration. This phenomenon has been determined by x-ray studies.\nThe dentist with whom you conferred is probably right in his\nobservations, but I believe that the gelantinous nature of the bone was. caused\nby bacterial invasion and continued maceration by secretions in the mouth.\nWe are constantly removing disintegrated bone in patients that have been treated\nby radium, which condition is entirely independent of carcinoma, and was\ncaused entirely by radium.\nIf there is any way that I can assist you in yor studies please\ncall upon me. I regret that conditions were such that I could not report to you\nbefore.\nWith kind regards, I am\nSincerely yours,\n(signed) W.L. Clark.\nP.S. I have directed that a reprint on objections to Radium Emanation in\nbare Tubes be sent you, from which you may glean some information."
}