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-7- habit of pointing their brushes. The dentists who have treated the girls em- ployed at the Orange Plant admit that pyorrhea existed in almost all of the cases. We studied the irritating effect of the luninous paint on guinea pigs and humans. The sides of a number of pigs wero shaven and paint ed dai ly with the luninous paint for two weeks. lle could not detect a reddening of the sicin either during the time that the paint was being applied or at any time after the exposure had ceased. Three of us in the laboratory painted an area on our ams with the paint and permitted it to remain on the skin for twonty-four hours. No orythema developed at any time after the removal of the paint though the observation was continued over two weeks. The gums of a number of guinea pigs and several goats were painted daily for a period of six months, but Suring that time no redness of the gum was noted. One of the goats lost two teeth at different times and we took pains to rub the paint into the gums until the now tooth oame through. Our observations were negative. (Our inquiries among the girls who often have painted small areas of the sicin with the material failed to revoal any cases of "burns". ) Unfortunately this goat broke its leg and was killed and cremated during our absence thus preventing us from examining the jaw bone. An x-ray picture talton provious to the accident gave a negative reading. One of course could not expect to find any maricod bone change in six months and a serios of animals should be studied over a period of years. This is especially true if intravenous injections of radio-active material is to continue. The radium thoriun sulphate is of the order of a hundred times less sol- uble than barivm sulphate. The question arose in our mind as to whether any of the radium material could be absorbed through the intestinal walls. We fed three guinea pigs 100 mgs. of luminous paint containing 2.90 mgs. of radium material per hundred grams of paint daily by placing the powder down Its throat and then washing it into the stomach with the minimum amount of water. The

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    "ocrText": "-7-\nhabit of pointing their brushes. The dentists who have treated the girls em-\nployed at the Orange Plant admit that pyorrhea existed in almost all of the cases.\nWe studied the irritating effect of the luninous paint on guinea pigs and\nhumans. The sides of a number of pigs wero shaven and paint ed dai ly with the\nluninous paint for two weeks. lle could not detect a reddening of the sicin either\nduring the time that the paint was being applied or at any time after the exposure\nhad ceased. Three of us in the laboratory painted an area on our ams with the\npaint and permitted it to remain on the skin for twonty-four hours. No orythema\ndeveloped at any time after the removal of the paint though the observation was\ncontinued over two weeks. The gums of a number of guinea pigs and several goats\nwere painted daily for a period of six months, but Suring that time no redness\nof the gum was noted. One of the goats lost two teeth at different times and\nwe took pains to rub the paint into the gums until the now tooth oame through.\nOur observations were negative. (Our inquiries among the girls who often have\npainted small areas of the sicin with the material failed to revoal any cases\nof \"burns\". ) Unfortunately this goat broke its leg and was killed and cremated\nduring our absence thus preventing us from examining the jaw bone. An x-ray\npicture talton provious to the accident gave a negative reading. One of course\ncould not expect to find any maricod bone change in six months and a serios of\nanimals should be studied over a period of years. This is especially true if\nintravenous injections of radio-active material is to continue.\nThe radium thoriun sulphate is of the order of a hundred times less sol-\nuble than barivm sulphate. The question arose in our mind as to whether any of\nthe radium material could be absorbed through the intestinal walls. We fed\nthree guinea pigs 100 mgs. of luminous paint containing 2.90 mgs. of radium\nmaterial per hundred grams of paint daily by placing the powder down Its throat\nand then washing it into the stomach with the minimum amount of water. The"
}