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Radium sulphate is one hundred times lesa soluble than barium sulphate. The berium salt is so insoluble that 1t is introduced in the intestinal tract so that it may be exemined by X-ray. Up to 1925, the literature did not show thet radium sulphate would remain in the body. Although there had been suggestions to the contrary, it was accepted that the insoluble salt when taken by nouth would pase direetly through the intestinal traet and from the body in a short period of timo. Redium was administered by sono doctors in the form of bromide, on the theory that it would remain in the body longer. It must be remembered that in considering all of the vidence prior to 1924 that nono or it is remotoly concerned with the dial peinting industry but with the knowledge and experiments of the soientific and modical world. There is no way to illustrate more emphatically what the 0X- perts in radium thought of the dial pinting industry than to recall thot even arter Dr. Martland's findings in 1925, Dr. Lind, Dr. ylinn, Dr. schlundt and Dr. Pohle disagreed with him, although thoy all eventually onme to ngree with him. It is apparent from the literature produced during this trinl that prior to 1925, although there was BODIO suggestion of hazard through the agonoy of radium, my hailed it as a great boon to humanity, and its internal uses by injection, inhalation, sto., were frequently advocated. That the articles by Hoffman followed by that of Martland, Conlon nad Knef in The Journal of the American Medical ABSOCIATION, published reapectivoly in september and December of 1925, startled the medical world, is demonstrated in the language of Lacessagne in his article entitled, *A New Professional Accident Among Handlers of Radioactive Meterials; Neorosis or the Maxillaries" 14. 14. Published in the Paris Medical, Zeb. 6, 1926, pp. 132-134, Exhibit P-14. -13-

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    "ocrText": "Radium sulphate is one hundred times lesa soluble than barium\nsulphate. The berium salt is so insoluble that 1t is introduced\nin the intestinal tract so that it may be exemined by X-ray. Up to\n1925, the literature did not show thet radium sulphate would remain\nin the body. Although there had been suggestions to the contrary,\nit was accepted that the insoluble salt when taken by nouth would\npase direetly through the intestinal traet and from the body in a\nshort period of timo. Redium was administered by sono doctors in\nthe form of bromide, on the theory that it would remain in the\nbody longer.\nIt must be remembered that in considering all of the vidence\nprior to 1924 that nono or it is remotoly concerned with the dial\npeinting industry but with the knowledge and experiments of the\nsoientific and modical world.\nThere is no way to illustrate more emphatically what the 0X-\nperts in radium thought of the dial pinting industry than to recall\nthot even arter Dr. Martland's findings in 1925, Dr. Lind, Dr. ylinn,\nDr. schlundt and Dr. Pohle disagreed with him, although thoy all\neventually onme to ngree with him.\nIt is apparent from the literature produced during this trinl\nthat prior to 1925, although there was BODIO suggestion of hazard\nthrough the agonoy of radium, my hailed it as a great boon to\nhumanity, and its internal uses by injection, inhalation, sto., were\nfrequently advocated. That the articles by Hoffman followed by that\nof Martland, Conlon nad Knef in The Journal of the American Medical\nABSOCIATION, published reapectivoly in september and December of\n1925, startled the medical world, is demonstrated in the language of\nLacessagne in his article entitled, *A New Professional Accident\nAmong Handlers of Radioactive Meterials; Neorosis or the Maxillaries\" 14.\n14. Published in the Paris Medical, Zeb. 6, 1926, pp. 132-134,\nExhibit P-14.\n-13-"
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