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        "Safety Light Collection",
        "Records Related to Radium Dial Painters"
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    "ocrText": "Page -3-\ngiven intravenously, intramuscularly or per os, is practically the same and that\nit is leas than 15.\n34.\nBased upon this work how long a period of time would you assume would be required\nby a patient, who had an injection of say 50 nicrograns of radium element,\nbefore it would be practically all aliminated?\n35.\nWould it not be practionlly all oliminated in six to eight montha?\n36.\nAro you faniliar with the work of Dominicie and his associates, published in the\nliterature around 1910 to 15, with roference to the internal administration of\nradium?\n37.\nIs it not a faot that Dominicie was directing his offorts towards devoloping a\nradium preparation which when once introduced into the sytem would remain for a\nlonger period of tine then the connon ordinary soluble salts?\n38,\nIs it not also true that Dominicie did not meet with much success in fixation of\nradium even when the colloidal radium sulphate was administered internally?\n39,\nDid he not find that this material was oliminated with about the sane expediency\nas the more soluble salts?\n40.\nI assume Doetor that you are versed in the solubility of the various products of\nradium, such as the chloride, bromide and sulphate, and that you are aware that\nthe chloride and bromide salts are readily soluble in aqua solutions, and that\nthe sulphate of radium is considered one of the most insoluble inorganic compounds\non which we have information.\nI further assune that you are avare that radium,\nand the more common element barium are analogous in their chenical behaviour, and\nthat even though barium sulphate is considered practically insoluble, that radium\nsulphate is 100 timea less soluble or has a solubility approximately 1/100 of\nbarious sulphate. Based upon these facts let us outline two cases: First -\nthat a definite amount of a soluble salt, such as radium chloride be taken by\nmouth, and second, that a like emount in the form of the sulphate be taken by\nmouth, what would be your assumption as to the course of the radium in these two\ninstances.\n41.\nWould you not assume in viow of the highly insoluble nature of radium sulphate\nthat it would practically all be eliminated thru the feces, and that a certain\namount of the soluble salt would in all probability be picked up by the blood\nstream? This question is puroly a hypothical one, and one which we ask for your\nopinion based upon the knowledge of the art as of 1915 and 1925, or any period\nbetween these dates, and not in view of the information which we have at the\npresent time?"
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