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(2) " (2) REQUIREMENTS. The list described in paragraph (1) shall, with respect to each brand of tobacco product of a manufacturer, include " (A) a list of all ingredients, constituents, substances, and compounds that are added to the tobacco (and the paper or filter of the product if applicable) in the manufacture of the tobacco product, for each brand of tobacco product so manufactured; " (B) a description of the quantity of the ingredients, constituents, substances, and compounds that are listed under subparagraph (A) with respect to each brand of tobacco product; "(C) a description of the nicotine content of the product, measured in milligrams of nicotine; " (D) with respect to cigarettes a description of-- "(i) the filter ventilation percentage (the level of air dilution in the cigarette as provided by the ventilation holes in the filter, described as a percentage) ; "(ii) the pH level of the smoke of the cigarette; and "(iii) the nicotine delivery level under average smoking conditions reported in milligrams of nicotine per cigarette; " (E) with respect to smokeless tobacco products a description of-- " (i) the pH level of the tobacco; " (ii) the moisture content of the tobacco expressed as a percentage of the weight of the tobacco; and "(iii) the nicotine content-- " (I) for each gram of the product, measured in milligrams of nicotine; " (II) expressed as a percentage of the dry weight of the tobacco; and " (III) with respect to unionized (free) nicotine, expressed as a percentage per gram of the tobacco and expressed in milligrams per gram of the tobacco; and " (F) any other information determined appropriate by the Secretary. " (b) SAFETY ASSESSMENTS. " (1) APPLICATION TO NEW INGREDIENTS. " (A) IN GENERAL. Not later than 1 year after the date of enactment of this chapter, and annually thereafter, each manufacturer shall submit to the Secretary a safety assessment for each new ingredient, constituent, substance, or compound that such manufacturer desires to make a part of a tobacco product. Such new ingredient, constituent, substance, or compound shall not be included in a tobacco product prior to approval of such a safety assessment. " (B) DEFINITION OF NEW INGREDIENT. For purposes of subparagraph (A), the term 'new ingredient, constituent,