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Jan-22-99 18:14 From-EGPediatricAlDSFdtn 2023712044 T-485 P.01 F-313 805 15th Street, NW Suite 500 The Elizabeth Glaser Washington, DC 20005 Phone: 202/371-0099 Pediatric AIDS Fax: 202/371-2044 Foundation Fax Linda Marson To: NOA Meyer From: Fax: Date: 1/22 Phone: Pages: Re: CC: Urgent For Review Please Comment Please Reply Please Recycle Comments: People Masacine stry. 10 0 pases attached Thanks Jan-22-89 18:14 From-EGPediatricAIDSFdtn 2023712044 T-485 P.02 F-313 IN THE ABSENCE OF ANGELS In an exclusive book excerpt, a Hollywood mother movingly describes her family's battle with AIDS By Elizabeth Glaser and Laura Palmer A decade ago, before the nation awakened to When I arrived at Cedars-Sinai Medical the daily nightmare that is AIDS, Elizabeth Center, my husband, Paul, rushed over, Glaser was infected with the virus through a and I could see the fear in his face. I was six tainted blood transfusion. She did not know months pregnant and had started bleed- that she had passed the virus on to her TWO ing. My baby wasn't due for 11 more children until her daughter, Ariel, developed weeks. the disease at age 4. For more than three 1 was diagnosed as having placenta pre- years, Elizabeth, 43, and her husband, direc- via, which meant the placenta was growing tor Paul Michael Glaser, 47, the former star of across my cervix. All we could do was pray the TV series Starsky and Hutch, kept their that I would stop bleeding, because my painful ordeal private. child was probably too small 10 live out- Then in 1989, just after the first anniversary side my body. I lay there, day after day, of Ariel's death, the Glasers went public with with Paul by my side, waiting. their story upon learning that a tabloid was On the sixth day, I was sent home and about to expose their tragedy in an unautho- told to stay in bed for the rest of my preg- rized feature. Since then, Elizabeth and writer nancy. I was so afraid that I did less than Laura Palmer have collaborated on In the Ab- whatever the doctor said I could. Each day sence of Angels, an inspiring account of the was a victory, the next, a challenge. Glaser family's struggles and triumphs, which Finally, on Aug. 4, 1981, Ariel Glaser will be published by G.P. Putnam's Sons in was delivered by cesarean section. She was February. "After we found out that my family three and a half weeks early and weighed was HIV-positive,' says Elizabeth, "it was clear five pounds, two ounces, but I didn't care. that I would have to grow as a person more When I looked into her eyes for the first than I had ever imagined in order to find a way time, I was amazed that this miracle was to cope. I wanted to let America see how painful mine. Our fears were gone. it is to be a family battling AIDS and how hard I was trying to tell the doctors how glad I it is 10 deal with the isolation and discrimina- was that it was over, when I heard the an- lion that comes through ignorance." " esthesiologist saying that something was The book is more than an anguished ac- wrong. 1 couldn't breathe. I hemorrhaged. count of a mother's loss; it is a testament to I was gasping for air. My doctor pushed on one woman's brave refusal to surrender. "If my stomach and I could feel the warm reading my story can help open hearts to peo- blood gushing out. I was too horrified to ple who are battling this disease,' says Eliza- even scream. What was happening to me? beth, "then maybe other families will have an The transfusions began. I watched the easier time." Here is a selection from In the dark red blood drip out of the squat plastic Absence of Angels. bag, flow through an IV tube and into a vein in my arm. I was transfused with seven May 1981 pints. After the doctors packed me with cotton I finally stopped bleeding. There were no words, no sounds, every- It wasn't until I saw my baby daughter thing was obliterated by a single focus, gel- again that the weariness and terror began ting to the hospital. It was as though I were to drift away, to be replaced with an in- motionless and the scenery was being stinctive love. She was beautiful, and we pulled past me. had both survived. It was over. I finally fell FROM THE BOOK IN THE ABSENCE OF ANGELS BY ELIZABETH GLASER AND LAURA PALMER. © 1991 BY ELIZA- DETH GLASER. TO BE PUBLISHED BY G.P. PUTNAM'S 60N9. A DIVISION OF THE PUTNAM BERKLEY GROUP INC. Jan-22-99 18:15 From-EGPediatricAlDSFdtn 2023712044 T-485 P.03 F-313 Bizabeth's hus- The Glasers in band, Paul Michael 1986, the year they Glaser (right), were diagnosed. "I played Starsky; Da- never imagined," vid Soul was Hutch says Elizabeth, "that in ABC's cop series this is what my life from 1975 to 1979. would be about." asleep, thinking about the wonderful life the three of us had to look forward to. Three wecks later I saw an article about a new virus called AIDS. I called my obste- trician immediately. "I just read an article in the paper about AIDS, a virus that may be transmitted by blood transfusions. I just got seven pints!" "Oh, Elizabeth," he said, "you've been through a difficult ordeal, but it's behind you. Relax and enjoy your baby. Your nightmare is over. AIDS isn't ever going to have anything to do with you." June 1975 I had pork chops, not passion, on my mind when I met Paul 15 years ago. I was com- ing home from a session with my therapist and determined to defrost two chops and have supper by myself. 1 had, in fact, just spent 50 minutes ex- plaining why I didn't need a man. Then, while waiting for the light to change at the intersection of Santa Monica and Beverly Boulevards, I looked at the car next to me. "Oh, my God, that is the cutest guy I have ever seen,"I thought. I smiled. He smiled. The light changed. I turned right. He turned right. I glanced into the rearview mirror and he signaled me over with his arm. I was anxious and jit- tery as I pulled over. He stepped out of his car and walked toward me. I rolled down my window and hc said, "Okay, let me see your driver's license." I looked at him and laughed. Hc was droll and disarming. 3 "What are you doing for dinner?" he Elizabeth, who asked. Thinking of therapy, I told him I gave birth to Ari (right) at 33, grew was going home and making pork chops. up in Hewlett Har- "Wouldn't you rather go out for Chinese bor, N.Y., and food?" "Yes," I said without missing a earned a master's beat, One therapy session thrown out the degree in early window. childhood educa- We went to Al Fong's in Beverly Hills. It tion at Boston Uni- was dark and the food was dreadful. Mid- versity. After o two- way through the moo shu pork I asked year marriage to a Paul what he did. He said, "I'm an actor." former classmate, I was so disappointed. I had lived in Los she moved to LA, where she was Angeles long enough to know that being teaching when she an actor meant absolutely nothing. met Paul. "Are you working?" I asked politely. "Ac- tually, I am. I'm in a show that's just been picked up by a network. It'll be on ABC in the fall.' "What's it called?" "Starsky and Hutch. It's a cop show about two detec- tives. I play Starsky." starting a family of my own. But Paul's hospitalized for more tests. The doctors I knew that night that even though he childhood had been more complicated, said they had no idea what was wrong with was an actor, this was the man for me. I and marriage and family were scary to Ariel, but for the next three days they was 27 and in love. When I looked at Paul I him. Paul and I talked it through, and he fi- watched her as if she might die. Once saw happily-ever-after. In September 1 nally agreed that we'd get married when we again I saw her life as precarious. I could moved into the one-room bungalow in the were ready to have children. feel all my dreams and plans start to crum- Hollywood Hills he shared with a dog Three months after our wedding in Au- ble. My many fears began to return. With- named Max. gust 1980, I was pregnant. All the good- out even knowing what was wrong, I was Paul didn't even have a television. We ness in the world seemed to be ours. In fighting for Ari's life all over again. watched the debut of Starsky and Hutch nine months I would have what I had al- By the time we left Florida in November with David Soul, the actor who played ways wanted most, a child of my own with Ariel was stronger, but not well. Doctors Hutch, at the home of David's agent. Ev- a man that I loved. there said that she suffered from a blood eryone, including the stars, felt the show When Ari was about a year and a half disorder that usually leads to kidney fail- would be cancelled in eight weeks. By old, we began looking for a larger house. ure. There was more color in her face and Thanksgiving, it was the hottest show on Paul and I wanted more children, and I lips, but she still had bouts of diarrhea and TV, and Paul and David were as famous as was trying to get pregnant again. From the would wake up in pain. Over the next few rock stars. moment I walked into the sprawling Medi- months we were doing test after test, trying Paul and 1 were both stunned by his in- terranean house in Santa Monica, 1 knew to diagnose the underlying cause of Ari's stant celebrity status. For years, he had this was the home for my family. Our chil- illness. Paul and I had told Ari there was worked steadily, doing everything from dren would grow up and go to college, and something funny with her blood and that Shakespeare to soaps. Starsky was not how then Glaser children would come home was the reason she was so frequently tired. he imagined becoming famous. There was with Glaser grandchildren. We told her that the doctors were going to a lot of adjusting to do. The simple joy of Everything seemed IO be going well. I find a way to make her better. taking a walk on the beach in our jeans and had gotten pregnant and had miscarried, As time went by and things still didn't sweatshirts came to a halt. Until you went but was pregnant once more. And on improve, Ariel was tested for all sorts of out in public with Paul, you had no sense Oct. 25, 1984, I delivered a beautiful son unusual diseases including lupus and leu- of how overwhelming, demanding, and ri- we named Jake. kemia. There was also talk of doing a liver diculous being a celebrity was. and kidney biopsy, but that was post- During the years that Starsky was on the In the spring of 1985 Paul was offered the poned. When each test came back nega- air, we never got involved in the social side job of directing his first feature film, Band tive, 1 felt we had won another diagnostic of Hollywood. We saved our money, of the Hand. The film was being shot in Mi- round. But Ari's doctor, Richard Fine, knowing that actors usually have lean ami, so we packed up the family and rented wasn't as cheerful. Hc knew what we times, and wanted to be prepared for that. a house on the beach for the three-month didn't-that Ari's diarrhea and low helper The price I paid for Paul's celebrity was in- shoot. T-cells count [an important part of the im- visibility. Hollywood people would nod From Miami I look the children to visit munc system that fights infection) were and smile when I would say 1 was a teacher my parents, who were living in Puerto symptoms of AIDS. or, later, an exhibits director at the Chil- Rico. Wc had just returned from that crip I don't think 1 was any more anxious dren's Museum. I had to find ways to ac- when Ari, who was then 4, started to have about an AIDS test than I was about any- cept that; one solution was to make a life stomach aches and cramps. She was in a thing else. Just as her doctors had ruled of my own that was independent and great deal of pain. We consulted a pediatri- out lupus and leukemia, they'd rule out strong. cian who said that she had probably picked AIDS. We took her in to be tested. I definitely knew I wanted to be married up a bug in Puerto Rico. When Ari didn't When the phone rang the next day, Paul and have children. I had had a wonderful get better, I went to another doctor who answered it and after he hung up he said, childhood and was looking forward to suggested a stomach specialist. He had Ari "They've got to run it again. It's shown 4 Jan-22-99 18:17 From-EGPediatricAlDSFdtr 2023712044 T-485 P.04 F-313 without telling my friends. They had been following An's illness since Miami, and their support and concern had been cru- cially important. Paul and I decided we had two choices. We could tell some friends or we could pick up, sell our house and begin our life all over again someplace else. The life we had known was over. I had to stay strong so I could save my chil- dren. Our first steps were perhaps the hardest. Paul and I decided to confide in only a handful of friends. I told my women friends in person, one by one, and made each of them promise not to tell anyone except their husbands. For some, whose children were playmates of Ari and Jake, finding out that we had AIDS was like finding out that for years their children had been in imminent danger. Most of our friends wanted to stand beside us, but they also wanted assurances that there was no risk to their children. In May of 1986, an- swers were in short supply and there were Paul and Ari took no guarantees. At first, no one would allow their chil- frequent outings to dren to come and play at our house. Some gether and often spent quiet mo- friends refused to let my kids come to their ments painting and homes at all. Some said their children reading of home. could continue to play with mine, but only at the park. Some dropped out of our lives. Reagan administration. But in those early The day after I told my yoga teacher years of the epidemic, that leadership was about our diagnosis she called IO tell me absent. AIDS may one day cost me my that she never wanted to see me again. We life, but community reaction right away asked a therapist to see if a child psychia- cost me the right to live the rest of my life trist would work with Ari when and if we the way I choose. That was my first fight. felt it was appropriate. I was later told that It was a time that would almost be un- psychiatrists would not sec my child, be- imaginable if we hadn't lived it. It is what all cause they were afraid if word leaked they families bauling AIDS had to face then. would lose too many other patients. You are told that you and your children one about our diagnosis because the expe- People were responding so fearfully may die. You are told that there are no an- riences of other families with AIDS had that I started to feel dangerous myself. swers now. And then as you are struggling not been positive. "The world is not ready The doctors said there was no reason for not to completely fall apart, you realize that for your family," was how he put it. fear, but that meant nothing because our very few people are going to reach out to Nevertheless, he said we needed to ei- ncighbors and our friends were not doc- help or comfort you. We felt so alone. We ther tell her nursery school or take her out tors. Every time I went into the supermar- wished for an angel who would help us get of it. The Centers for Disease Control ket, I envisioned everyone slowly and si- through it all. But at that time it seemed we guidelines, at that time, said that a child lently moving away as if they had just seen had no angels watching over us. with AIDS should not be in nursery school a rattlesnake. It would bc nine months be- without first getting permission from the fore the Surgeon General would appear July 1986 school. It was surreal. Along with this hid- on television to say flat out that you can't eous medical diagnosis came instructions gel AIDS from saliva or kissing. And with One of the telephone calls I dreaded most on how we needed to handle the rest of the that information, our lives slowly regained was to Crossroads Elementary School, world. some normalcy. where Ari had becn accepted. Both Paul Dr. Stiehm told me that I could test pos- When we told people, we forced them to and I desperately wanted her to start kin- itive and carry the AIDS virus without be- enlist in a conspiracy of silence. The quali- dergarten that fall. It was one of the few di- ing symptomatic or showing any signs of ty of our lives now hinged on the ability of rect links WC had to the future, and it the disease. In other words, there was a big our friends to keep quiet. Were word 10 get meant so much to Ari. Paul Cummins, the difference berween being HIV-positive out, we knew we would be treated like school's headmaster, had no idea why I'd and having full-blown AIDS. Although plague victims for no reason. All of us walked into his office. He seemed both Jake had tested positive, his other tests were very afraid and confuscd. confident and relaxed. I took a deep breath were all normal. What could have stopped the fear and before I began. I told Dr. Stichm that I could not live hysteria was strong leadership from the "We were planning on having our Jan-22-99 18:18 From-EGPediatricAlDSFdtn 2023712044 T-485 P.05/08 F-313 make longe angr ing U of a I came was could It 1 the t J tors, è to fo there frien Paul eryo pass lean pois wan B am ther ing sick thin I'm I I sa live exc my col ryf ] tha The family spent the following year, after the Crossroads board that never seemed to happen. I wished An happy summer abl had agreed 10 admit children with AIDS. would be invited to someone's house for a holidays in Maine. SOI Ir was there Ari's Says Elizabech: "It was another hard lesson in sleepover. I wished one of Jake's friends you health seriously be how little could be taken for granted." would invite him for a play datc. It would no gan to fail in 1987. be lovely if Paul and I were invited to a din- ch While 1 was fighting my battles, Paul was ner party. daughter, Ariel, start kindergarten here in coming to grips with his own private At that point in our lives, coping with Pa September," 1 said. "But I just found out war-a battlefield on which he might lose lear was far worse than coping with AIDS. the that she, my son and I are all infected with all those he loved. It was a difficult strug- The fear of rejection or exposure was with we the AIDS virus." I started to cry. I was sure gle for him then and it still is now. He us at all times. Most people have night- M he would send me away and tell me to find worked as much as he could, as that gave mares when they sleep, but when you are a in another school. Paul Cummins walked him the strength to keep going. Sometimes family facing AIDS, the nightmare begins M over and put his arms around me. "You it is hard for me to believe that my life is fresh each day. Sleep is the only time when an are part of our family," he said. "We want real, but trying to imagine being Paul is I feel just like everyone else. Often I wake te) you here." He held me as I cried. I left his even more difficult. up in the morning having forgotten for an WI office feeling both relief and joy. As long Ariel was doing well. Each morning I instant about AIDS, but that lasts for only sh as 1 could see that not every door was go- would sit with her and pick out the hair a blink of an eye. m ing to be closed to us, 1 could hope. ribbons she would want to wear. We In the fall of 1986, the doctors still had pa would stand in front of the bathroom mir- no answers. Naively, I thought we were be Ari had spent just one week all Crossmads ror and I would brush her hair 100 times to ahead of the game. Since none of us was W. when Cummins met with the Glasers to ex- make it shine. As her hair glistened, silent sick or deteriorating, I felt that maybe if we A plain that the school's board was about to tears would fill my eyes and my heart could just stay strong, doctors would find lo draft an AIDS policy. He was concerned that would break, knowing that I might lose a cure. Ari was alrcady five years old, while Ari's presence in the school might jeopardize her. It became impossible for me to ever most children with AIDS died by the time its passage. So Ari was uprooled and trans- feel really happy without feeling achingly they were two. ferred 10 a nearby public school that already sad. I felt I had every right to be angry. But th had an AIDS policy. where she remained until That autumn, I kept wishing for things what good was it going to do? Would it ti Jan-22-99 18:19 rom-EGPedi 2023712044 T-485 P.06/08 F-313 longer? I couldn't stop myself from being "What do you mean! Il ready IUI angry, but I could keep that anger from be- me!" Although I hadn't needed to start ing trapped inside my body. I would think taking it yet, I knew it was available. of a room with two doors. If the anger "AZT hasn't been approved for pediat- came in one door, I tried to be sure there ric use. It's just not ready." was always another door so the anger "We've got to find a way to get it and could get out. use it." I had to learn to forgive. 1 had to forgive "Elizabeth," he said, "we don't even the blood donor. I had to forgive the doc- know the dose to give her. We can't just ex- tors, the hospitals, the schools, and I had periment. It could kill her." to forgive fate. I had to forgive God, if "When will it be ready?" there is one, and I had to forgive my "In the fall." friends, who had to forgive me. Right away I took a deep breath and prayed that WC Paul saw that we would have to forgive CV- could hold on until then. eryone, that we would have to let the anger By the time we got home, Ari was thin- pass right through us. He helped me to ner and weaker, but Dr. Stiehm felt she learn this. It was bitterly hard. Anger is a would still be able to start school. She had poison that will seep into your system and her heart set on beginning first grade. It want to stay. didn't work. Although Ariel looked beauti- But J still get angry. Sometimes when I ful with her shiny hair and luminous blue cyes, she frequently had outbursts of Avid skiers, the am alone in my car I scream, "If you are Glasers vacationed there, God, I hate you! I hate you for mak- ghastly pain. She was a valiant fighter but en famille in Park ing this my life. I hate you for letting Ari get was only able to finish two weeks of first City, Utah, shortly sick. And I hate you because I don't really grade. after Jake's birth think you are there." My throat hurts when As the pain increased, Ari and 1 became in 1984. I'm done, but I usually feel calmer. more and more like one person. In her I would feel a painful jealousy whenever worst moments, my eyes would stan 10 fill Some nights I would just lie there and I saw people who seemed to have normal with tears and I would say, "Oh, Ari, I think how trapped Paul must feel. How lives and healthy children. I would feel an wish I could take all your pain into my hard it was to live with us and how impos- excruciating envy toward strangers and body. I wish 1 could make it all go away." sible it would be to leave. If he walked my friends who could have what I never She would look right into my eyes and very away, everyone would think he was such a could. And then I would feel very, very sor- slowly answer, "But you can't, Mom." We "bad" guy. But I knew he must have want- ry for myself. both knew it was true. ed to run away at times. Part of me would I learned to let go of all of these emotions We would cherish the good moments have wanted that. But he never said it, we that depleted me. I am never going to be more than ever. Paul would take Ari to the never shared what we were thinking. It was able to have what other people have. At end of the block to feed the pigeons, and at too scary. On a good night we would fall some point you begin to accept that this is night he would lie beside her in bed and asleep in each other's arms. your life. I've learned that you often have make up wonderful fanciful stories. Ari was getting weaker and weaker. We no say in what happens to you, but you can In the fall parents started getting curi- had been waiting for AZT all that year and choose how you bear the consequences. ous about Ari's long absence from school. each month it wasn't ready. Paul and 1 were Rumors were raging and several parents silently praying that something would Paul had finished directing Running Man in asked the school's director if Ariel Glaser change the course of our lives, working the spring (of 1987], and we had decided had AIDS. Each time we found out that hard to keep optimistic. we would make our annual summer trip to someone was asking, our anxiety soared. Maine. We were swimming, boating, hik- Paul and I still felt the risks of going public Shortly before Thanksgiving 1987. Ari was ing or picking wild blueberries on Pleasant clearly overshadowed any gains. As awful hospitalized with acute pancreatitis. She was Mountain. At night we would make a fire as it had been for us to shoulder the mas- released after four weeks but had to continue and toast marshmallows. Simple and in- sive weight of the secret for the previous being fed through an elaborate intravenous tense delight. But Ari started to seem year and a half, we dreaded even more the system. which Paul and Elizabeth mastered so weak, and I sensed for the first time that risk that our children might experience any that they could cure for their daughter at she was beginning to fail. Her appetite di- of the hysterical fear that still surrounded home. Ari began taking AZT orally right be- minished and she complained of stomach AIDS in many parts of the country. fore Christmas, but the drug had no positive pain. In past summers she had always Paul and I had stopped going out, ex- effect. been eager to go in the canoe and bc by the cept with the few who were pledged to se- water, but now that eagerness was gone. crecy. Our friends worked as hard to pro- Through January of 1988 Алі became As a mother, I knew instinctively that I was lect our privacy as we did. At night, more confined. By February she stopped losing her. Paul and I would climb into bed exhausted walking completely. We didn't know why. I called Dick Stiehm in Los Angeles. by the strain of just being us. If we talked The doctors had по answers. 1 carried her "We'vc got to get AZT now," I said. about our fears, we felt overwhelmed. If everywhere. She was unable to speak, but "She's starting to fail." In 1987, AZT was we talked about our hopes, it fell like pie- we both remembered the words that had the only treatment that seemed to be effec- in-the-sky dreaming. So usually, we didn't already been said. We would still go for tive against AIDS. talk at all. long walks. 1 would put her in the stroller, Jan-22-99 18:18 From-EGPediatricAlDSFdtn 2023712044 T-485 P.07/08 F-313 COVER from the hospital, Elizabeth discussed her in- Dr. Stiehm had already tried to get AZT in that tentions with Paul. form for several of his patients but had failed because it was still only available for trial test- cushioning her with pillows and wrapping Paul was silent for a long time and then ing. Elizabeth returned home and refused to a blanket over her legs. Despite the pain with great gentleness he said, "I'll support give up until she was able 10 obtain the intrave- and the weariness that she always felt, she you in whatever you have to do." I gave my nous drug for her daughter in May 1988. never failed to respond to the beauty husband a big hug and felt a smile spread- around her. ing across my face. I knew this was the I sat in my den, relieved that we had suc- In March 1988, nearly two years after moment when I was taking that hard first ceeded in getting the drug and furious at our initial diagnosis, the guillotine fell. Ar- step. I didn't know it at the time, but it was the inhumanity of a system that cared iel got pneumonia and we were back at the step that has kept me in motion ever more about rules than lives. Did I love my UCLA again. We learned that her brain since. child any more than the mother in Harlem, had severely acrophied. The doctors said it As a member of a family struggling with Miami or Newark loved her child? Abso- was irreversible. It was one of the central AIDS, I learned that few wanted to help lutely not. Did Ari deserve a chance any nervous system complications of AIDS enough to change a system that had be- more than their children? No. Every child that is quite common in children, though come strangled by red tape. The ones who with AIDS deserves a chance. And what not in adults. tried were often ignored because AIDS about the children who had no one to After four days, Dick Stiehm solemnly was something many refused to deal with. speak for them? Then, three weeks to the day after we started intravenous AZT, 1 walked into Ar- iel's room in the morning and she looked up and said, "Good morning, Mom. I love you." I could hardly believe it. Ari was back! The sky had opened up. I had to find Paul. Maybe miracles did happen. Maybe one was going to happen in our house. Ari continued to improve over the next six weeks. The intravenous AZT was un- winding her cocoon of paralysis, and her 6-year-old self was still underneath. The whole world had started spinning again. Last fall, Helen Ал, on a Mar- Hayes honored tha's Vineyard Elizabeth and gave beach, in 1987. her a donation on By then, she had behalf of a Manhat- started napping tan hospital, every day. sat us down and told us that Ari had prob- Someone had to care enough to bc willing In March we were told to prepare for a fu- toi ably 48 hours to live. She was breathing to shake things up, but I didn't know who neral. By May we had a shot at second weakly. but what none of us knew then was it would be. I realized my country was fail- grade. If Ari could make it, we were all go- gel that she hadn't given up. ing me. The compassion as well as the ing to make it. qu It was not until the doctors told us that moral and ethical foundations of our soci- wa there was absolutely no hope that I con- ety werc being tested, and from my point In June, friends arranged a meeting between ate fronted the possibility of Ari's death for of view, America had let me down. Elizabeth and the Reaguns at the White wa the first time. I sat with a friend and fit one House, where she appealed to the President to the cigarette after another. I was shaking and Determined to educate herself about AIDS as lead the nation on this urgent issue. Although to not yet able to talk. "No one cares if WC all a national issue, Elizabeth met with physi- the Reagans welcomed her warmly, their pri- die from AIDS," I said. "Something is cians, politicians and friends to plan an as- vate concern had no positive impact on public UI very wrong. I have to get to the President." sault on policymakers in Washington, D.C. policy. The more Elizabeth learned about the CO It was in that moment of honest desper- Her first goal was to explain that AIDS affects government's indifference 10 the issue of tal ation that I realized I could no longer sit children differently than adults and then 10 children with AIDS, the more determined she ha quietly in Santa Monica. A mother's job is persuade legislators to make federal funds became to form a private foundation 10 raise pe to save her child; it's a basic animal in- available, specifically for pediatric AIDS re- funds for pediatric AIDS research. ot stinct. But I was failing. I had to do more. search. During her visit 10 the capital six weeks vi later, Elizabeth also met Dr. Phil Pizzo, chief July 1988 in Propelled by anger and frustration, Elizabeth of pediatrics at the National Cancer Institute W: considered ways to take a more active role in in Bethesda, Md., who had launched the It was one of those beautiful Los Angeles ne AIDS issues without compromising her fam- first federal study of AIDS in children. When days when the sun, air, sky and sea all seem ily's privacy. Ariel survived the pneumonia, he learned that Ari had been taking AZT oral- perfect. I asked Ari if she would like to go th yet her health seemed ever more fragile. The ty with no favorable results, he recommend- down to the Santa Monica pier, which has U day the Glasers brought their daughter home ed that she take the drug intravenously. rides and an amusement arcade with cot- Wi Jan-22-99 18:20 From-EGPedi IDSFdtn 2023712044 T-485 P.08/08 F-313 ton candy and stuffed animals for prizes. An had regressed greatly. In a few weeks, daughter had died. Ariel Glaser had been Ari and I went on the Ferris wheel to- we had slid back down the mountain we on the earth for seven years and eight gether, around and around, waving wildly, had climbed since June. Her care was in- days. queens of the sky and sea. For a moment, I tricate and complex, but all I wanted was was experiencing the thrilling unadulter- to take her home. That Sunday, the Glasers held a memorial ated joy of just being a mom. Maybe there Three weeks later, on Friday, Aug. 12th, service for Ariel at home, and on Tuesday, was some part of Ariel that knew this was 1988, we were packing up her things. Ari Aug. 16, their daughter was buried next to the last day that she was really going to get was lying in her bed and I said to her, "We Paul's father at a cemelery in Boston. to be a little girl. have to sce if you can sit in your stroller, Two weeks later Ari was readmitted to honey." And Ari said, "No, Mom, I'm go- We have left Ari's room just as it was when UCLA hospital. Her white blood cell ing to walk home." She couldn't move her she was alive. Paul and I decided we count had fallen too low, and we had to legs. I looked at her and said, "Give me a couldn't imagine changing it. We each find take her off the intravenous AZT. She was break." Ari said simply, "No, Mom, I'm our way into her room at different times having fevers that we couldn't break. But I going to walk home." "All right, Ari," I and in different ways to tell her we love her. persistently believed that this was just an- said. "Go for it." Her door is always open. It's not maudlin; other crisis that we would somehow sur- Paul and I continued getting her things it's just life. Ari's room remains though Ari vive. I have never been ablc to accept end- together. It was not until the last 10 min- is gone and her spirit fills our hearts. ings that I don't like. I fight to make life the utes of her life that I knew she was dying. way I want it to be, and because of that I And then very quickly she was gone. She As In the Absence of Angels continues, it never believed that Ari was going to die. was never supposed to die, It was too chronicles Elizabeth's evolution from a des- We had Ari's seventh birthday party in short a time to have had her. Paul wept perate mother, crying out for action, to an im- the hospital, and Dick Stiehm gave her a and I cried, "Noooo!" It was a "no" that passioned advocate, in charge of her life and UCLA T-shirt and told her it was what she wanted to turn back time. It was a "no" to determined to help others. For a look at Eliza- would wear on the day she went home. But a world that had failed me. Our beautiful beth today, please turn the page. Photographs from the collection of Elizabeth Closer http://www.pedaids.org/facts.html Pediatric HIV/AIDS Fact Sheet Children In the U.S It is estimated that the number of children infected with HIV in the U.S. is 15,000 through 1994-1995. Note: 31 states require reporting of HIV infection. Two of those states, Connecticut and Texas, have confidential reporting only for children less than 13 years of age and Oregon requires reporting only for children less than 6 years of age. AIDS is the seventh leading cause of death for children 1-4 years of age in the U.S. Between 15% to 30% of infants born to untreated HIV-infected women become infected with the virus. Studies show that treatment can help reduce the rate of HIV transmission from an infected woman to her baby to less than 8%. Of the 12 drugs currently approved for the treatment of HIV/AIDS, only seven are approved for pediatric use: AZT (retrovir), ddl, d4T, 3TC (epivir), Norvir (ritonavir), Viracept (nelfinavir) and Sustiva (efavirenz). No protease inhibitor is approved for infants under the age of two. Today, nearly 100% of new HIV infections in children result from an HIV-infected pregnant woman passing the virus to her baby either before or during birth. Approximately 30,000 American children have already lost their parents to AIDS. Worldwide UNAIDS estimates that 1,600 children under the age of 15 are infected with HIV each day worldwide 1,200 children die of AIDS each day worldwide. By the year 2020, there will be over 40 million orphans under the age of 15 in the 23 countries most affected by HIV. Most of these children will have lost both parents to AIDS. Nearly 600,000 children were infected with HIV in 1997, mostly through their mothers before or during birth or through breastfeeding. Altogether, 2.7 million children have died of AIDS since the beginning of the epidemic. Another million were estimated to be living with HIV disease at the end of 1997, half of them infected last year alone. Adolescents In the U.S 25% of new HIV infections in America occur in people under twenty years of age. This represents two new adolescent HIV infections every hour. Every year, 3 million American teenagers acquire a sexually transmitted disease, leaving them more susceptible to HIV infection. Worldwide Worldwide, more than half of all new НИѴ infections acquired after infancy occur among young people 10-24 years of age. Of the 30 million persons living with HIV worldwide, at least a third are young people 10-24 years of age. Every day, 7,000 young people 10-24 years of age worldwide acquire the virus. This translates into five young people every minute or 2.6 million infections each year. 1 of 4 1/25/99 1:32 PM http://www.pedaids.org/facts.html Women of Child-bearing Age In the U.S AIDS is now ranked as the leading cause of death among African-American women ages 25-44. AIDS is now ranked as the third leading cause of death among all American women ages 25-44. From 1985 to 1996, the proportion of U.S. AIDS cases in women reported each year increased from 7 percent to 20 percent. Worldwide Approximately 42% of the 21.8 million adults living with HIV/AIDS worldwide are women. Nine out of ten HIV-positive women in developing countries have no idea they are infected. In the U.S. fewer than 5% of children born to HIV-positive women in 1997 were infected with the virus. In developing countries, the average was between 25% and 35%. There are two major reasons for the difference- breastfeeding practices and access to drugs for reducing mother-to-child transmission. Data from the Centers for Disease Control and Prevention, UNAIDS and the World Health Organization. For specific citation information, please contact Chris at 310-314-1459 or e-mail [email protected] Updated 7/15/98 Back to Home Page National Organizations (revised 4/8/98) For statistics regarding HIV/AIDS: Centers for Disease Control & Prevention (CDC) 301-436-8500 For general information about HIV/AIDS, AIDS related resources & services, prevention materials, referrals & publications, funding information and clinical trials call: CDC National AIDS Clearinghouse 800-458-5231 For general questions about HIV and for educational materials: CDC National AIDS Hotline 800-342-AIDS For general questions about HIV (in Spanish or Asian languages): Bilingual AIDS Hotline 800-367-2437 For questions or information on international programs: 2 of 4 1/25/99 1:32 PM Jan-22-99 18:02 From-EGPediat DSFdtn 2023712044 T-484 P.23/33 F-312 THE ELIZABETH GLASER SCIENTISTS AWARDS > > 1999 HONOREES - PROFILES AND INTERVIEWS > > > > ROBERT DOMS, M.D., Ph. D. University of Pennsylvania Associate Professor, Pathology and Laboratory Medicine > Area of Investigation: Study the role of chemokine receptors in HIV infection. > Background: In 1996, Dr. Doms led one of five groups that independently >identified the chemokine receptor CCR5 as playing a critical role in the >entry of the most common types of HIV into cells. Working with colleagues >in Belgium, he subsequently found a polymorphism in the CCR5 gene that >renders approximately one percent of Caucasians CCR5 negative - explaining >why some people remain HIV-negative despite repeated exposure to the >virus. The Elizabeth Glaser Scientist Award will help Dr. Doms continue >his studies on HIV pathogensis in the pediatric population. > QUESTIONS AND ANSWERS > 1. How would you explain the significance of your work to a layperson? My team and I are focused on chemokine receptors - specialized proteins that function at the surface of cells and allow molecules to trigger internal cell processes without actually entering the cell - as tools to understand how the virus works and come up with new therapeutic strategies. If we can stop the virus from getting into the cells, obviously, we can stop the infection -- that is the point of vaccines. V For HIV to get into a cell it has to do a couple of things, starting with latching on to the outside of the cell by binding to the CD4 molecule which is found on the surface of cells found in the immune system. It then has to get inside the cell through a process called Dons lot 3 Jan-22-99 18:03 From-EGPediatricAIDSFdtn 2023712044 T-484 P.24/33 F-312 membrane fusion. It had been known for some time that CD4 by itself was enough for the virus to latch on to the cell, but was not enough for it to get inside the cell - the virus needed something else to get into cells, and this 'something else' eluded discovery for over a dccade. However, in 1996, a molecule or co-receptor called CXCR4 was discovered. In conjunction with CD4, CXCR4 that allows the virus to get into the cell to start an infection. Interestingly, it was also discovered that CXCR4 worked for some types of HIV but not others. Specifically, it was clear that CXCR4 didn't work for M- tropic viruses, the most common kinds of viruses that infect children and adults. Therefore, it was important to find the co-receptor that worked for M-tropic viruses because then we can understand how these viruscs get into cells and we could find new ways to block it. > In 1996, we found that the CCR5 molecule that holds the key for entry of these M-tropic viruses into cells. Then, continuing our work with Marc Parmentier and his colleagues in Belgium, we discovered that one- percent of Caucasians naturally lack CCR5 because of a naturally occurring mutation in the gene. Those individuals who lack CCR5 are highly resistant to HIV infection but are otherwise normal. The goal was then to come up with some kind of strategy to stop the virus from using CCR5 -- to develop an anti-viral drug. > 2. How will your research under the Foundation grant be implemented in the pediatric HIV/AIDS population? We now know that viruses throughout the world use CCR5. That suggests a commonality that allows them to recognize the CCR5 molecule. Just this past summer it was discovered that gp120, the protein that coats the outside of HIV, has a very highly conserved region that interacts with CCR5. We have discovered a way to trick the virus to expose this conserved region and hope to accomplish one of two things: make antibodies to this region and to then come up with new vaccines that target this region. Sccondly, we want to expose the region and come up with drugs that will bind to this area and prevent HIV from using the CCR5 receptor. Another component of our work will attempt to explain some of the differences in clinical symptoms in people with HIV on the basis of the kinds of co-receptors used by the viruses. Wc have been able to make antibodies 10 many of these receptors and we want to find out where these receptors are expressed in both children and adults. This will give us a clue as to which types of cells might potentially be infectable by different types of viruses. It may also help us explain some differences between pediatric and adult AIDS. > Dons 20+3 Jan-22-99 18:03 From-EGPediatric. :AIDSFdtn 2023712044 T-484 P.25/33 F-312 3. What does funding from a Foundation such as ours mean to your creativity as a scientist? Historically, the system for getting grants almost forces people to be scientifically safe because they are worried that if they propose something too unique, too risky, they simply won't get funded. Funding from a private Foundation enables you to take more risky and creative approaches to new and interesting avenues of research. When you get funding from the Pediatric AIDS Foundation, it is a very substantive grant that allows you to move your research into new and challenging directions. 4. What does it mean to be an Elizabeth Glaser Scientist? I remember hearing Elizabeth Glaser speak in 1992 at the Convention. It is quite an honor to receive an award named after her. When you ask yourself what you can do as a person to make a difference you look to her example as really showing the way. She demonstrated how one individual can make a positive difference. 5. We have come SO far in the past decade, what does the next decade of >progress on pediatric HIV/AIDS research look like? We are making progress and things are much more promising than they have been. There are some effective drug therapies helping a lot of people -- but people can develop resistance and the drugs are just too expensive. In Uganda, there are about a million HIV-positive individuals, but only very few can afford the triple-drug cocktail. We clearly need new therapeutic strategies. > Through basic research we are beginning to unravel this very complicated virus. I think we will develop new drugs to target the virus or the chemokine receptors. Obviously, what we really need is a vaccine, but that is going to be a slow and complex process because this virus changes its spots so readily. I think in the next decade there will be more progress in developing drugs to help knock this virus down, but we have to keep working on new ways to come up with a vaccine. New approaches, such as the conserved region approach, are exactly the kind of new investigative angles we need on the vaccine front. Dons 3 of 3 # 16 Jan-22-99 18:03 From-EGPediatricAlDSFdtn 2023712044 T-484 P.26/33 F-312 THE ELIZABETH GLASER SCIENTISTS AWARDS » 1999 HONOREES - PROFILES AND INTERVIEWS » » Philip Goulder, M.D., Ph.D. » Instructor in Medicine » Massachusetts General Hospital, Boston » » Area of Investigation: HIV-infected children progress to disease more >>rapidly than adults. One possible explanation is that the immune response >>to HIV is defective in children. This study aims to investigate the cells >>normally responsible for eliminating virus infections known as Cytotoxic "killer" T-lymphocytes. » Background: Dr. Goulder began his investigative career at Oxford where >>he developed a number of techniques to examine immune function in HIV-1 >>infected children, which is his main area of focus. His experience as >>a pediatrician and the novel technologies he has developed place him in >>a unique position to define the role of immune responses in children >>infected with the virus and will impact our understanding of HIV >>pathogenesis and the prospects for immunotherapy. » >> » QUESTIONS AND ANSWERS » >> 1. How would you explain the significance of your work to a layperson? Our ultimate goal is to develop a vaccine designed especially for children. We know that HIV-infected children progress to disease more quickly than adults. We also believe that the cells normally responsible for eliminating virus infections, known as Cytotoxic "killer" T-lymphocytes (CTL) play a central role in controlling HIV in adult infection. One possible explanation for the rapid progression generally seen in HIV-infected children is that their "killer" T-cell response is defective in some way. Recent advances in the technology available have allowed us the opportunity for the first time to make a detailed study of the "killer" T cell response in children. The long-term Goulder lot 3 3 Jan-22-99 18:04 From-EGPediatricAIDSFdtn 2023712044 T-484 P.27/33 F-312 goal is to identify components of the immune response that are important in protecting against HIV disease, and which may ultimately be important to vaccine design. » 2. How will your research under the Foundation grant be implemented in >>the pediatric HIV/AIDS population? >> We are already studying HIV-infected children here in North America, and we will continue with these studies. However, the global epidemic is concentrated elsewhere, and much of our research effort will focus on HIV-infected mothers and children in South Africa. Over one-third of the Zulu mothers in Durban, South Africa, where our collaborations are centered, are HIV-infected. One other important reason for directing our research effort towards this region is that the commonest strain of HIV worldwide ('clade C') is infecting this South African population, and this is likely to be relevant for vaccine design. >> 3. What does funding from a Foundation such as ours mean to your >>creativity as a scientist? Five years of funding provides the stability and support for ambitious and important projects to be planned and carried out. For a pediatrician who research focuses on pediatric HIV the PAF has international recognition and the close association with it can only be helpful in developing collaborations and setting up studies with people whose priorities and goals overlap with those of the PAF. » 4. What does it mean to be an Elizabeth Glaser Scientist? It is a great honor to be bracketed with the other EG Scientists, who are clearly highly creative and talented individuals. The Pediatric AIDS Foundation deservedly has a reputation for practicing scientific research the way it should be done - that is, in truly collaborative way, so that rapid progress may to be made towards eliminating HIV. I believe that this "team" approach is the right approach and I am very excited to be joining a team whose priorities and research interests overlap so much with my own. » 5. This year marks the Foundation's 10th Anniversary. We have come so >>far in the past decade, what might the next decade of progress on Goulder 20+3 Jan-22-99 18:04 From-EGPediatricAlDSFdtn 2023712044 T-484 P.28/33 F-312 >>pediatric HIV/AIDS research look like? I would hope the next decade will put us squarely on the path toward developing a vaccine for HIV - for children as well as adults. Ultimately, a vaccine is our only real hope for impacting this disease. While implementation of a successful vaccine is years away, if we wait to develop HIV vaccines for children until after they are proven effective for adults, we will lose millions of children to this pandemic. Goulder 30t3 3 Jan-22-99 18:04 From-EGPedi IDSFdtn 2023712044 T-484 P.29/33 F-312 THE ELIZABETH GLASER SCIENTISTS AWARDS 1999 HONOREES - PROFILES AND INTERVIEWS PAUL JOHNSON, M.D. HARVARD MEDICAL SCHOOL Associate Professor of Medicine, Chairman of the Immunology Division, Partners AIDS Research Center Harvard Medical School. Area of Investigation: CD4+ T helper Cell Function in Macaques to combat SIV infection in Pediatric patients. CD4+T lymphocytes play a central role in the war between the AIDS virus and the body's immune system. Background: Dr. Johnson has focused on analysis of HIV-specific cytotoxic T lymphocytes (CTL), research that has established him as a leading investigator in the field of cellular immunology. Since being appointed as Chairman of the Division of Immunology in 1994, Dr. Johnson has led a successful research program focused on immunology related to AIDS pathogenesis and vaccine development. More recent research has analyzed T cell turnover in SIV infection and the development of gene therapy for AIDS. QUESTIONS AND ANSWERS 1. How would you explain the significance of your work to a layperson? I am trying to better understand the role that CD4+T cells play in helping children to fight off HIV infection. CD4 cells are the major cells responsible both for fighting off infection and also the main target that HIV infects and destroys. By studying monkeys infected with a closely related AIDS virus, I hope to understand both how quickly CD4+ T-cells are killed and regenerated and also understand how they recognize the AIDS virus. This information should help us could restore those critical immune responses via either treatment with anti-retroviral therapy, immunization or a combination of the two. 2. How will your research under the Foundation grant be implemented in the pediatric HIV/AIDS population? The hope is that our research with Macaques could help us to design an approach to help boost the immune response against HIV in HIV-infected children. If this is successful, it would help us design techniques for therapeutic immunization - - meaning that it might allow their immune system TO better contain the virus Johnson Mg lote Jan-22-99 18:04 From-EGPediatricAlDSFdtn 2023712044 T-484 P.30/33 F-312 replication, either as a supplement to antiviral therapy or if the antiviral therapy fails for some reason, allow them to better contain viral replication without drugs. 3. What does funding from a Foundation such as ours mean to your creativity as a scientist? What's really unique about the Foundation is the group of scientists that are affiliated with it? The chance to interact with the outstanding group of Glaser scientists is an exceptional opportunity. The ability to contrast results and share ideas at the conferences that the Foundation sponsors is very exciting, because that degree of focus and level of interaction is quite unique. 4. What does it mean to be an Elizabeth Glaser Scientist? It's a tremendous honor and responsibility. I've heard so much about Elizabeth over the years and besides the scientific opportunity, it is simply a personal honor for me. 5. This year marks the Foundation's 10th Anniversary. We have come so far in the past decade, what might the next decade of progress on pediatric HIV/AIDS research look like? I would hope the research over the next decade would help us to better understand how we can rebuild the immune system of people infected with the AIDS virus. We have now a number of scientific tools at our disposal and the challenge will be to see how we use those tools to rebuild the immune system to lead to prolonged gains in the health of HIV- infected kids. Johnson zot 2 # 21 Jan-22-99 18:05 From-EGPediatricAlDSFdtn 2023712044 T-484 P.31/33 F-312 THE ELIZABETH GLASER SCIENTISTS AWARDS 1999 HONOREES - PROFILES AND INTERVIEWS JULIE OVERBAUGH, Ph. D. Full Member, Fred Hutchinson Cancer Research Center Seattle Area of Investigation: Leading an effort to study how HIV virus is transmitted through breast feeding by using a collection of samples from a recently completed clinical trial of breast feeding transmission of HIV in Kenya. Since 1992, Dr. Overbaugh has been a member of the Nairobi HIV/STD Research Project, an international collaborative group based at the University of Nairobi. Background: In the past decade, strategies to limit HIV transmission to newborns have been implemented in developed countries as a result of research showing the effectiveness of treatment around the time of delivery. Moreover, in developed countries, women infected with HIV are counseled not to breast feed, which further reduces the infant's exposure to HIV. However, in resource-poor settings, many continue not to have access to adequate health care, including new drugs that can prevent their babies from acquiring HIV. In these situations, breast feeding is also more common. Dr. Overbaugh is pursuing studies that are designed to help devise ways to further reduce HIV transmission to infants, including during breast feeding. QUESTIONS AND ANSWERS 1. How would you explain the significance of your work to a layperson? I am part of a large, collaborative research team that is conducting a clinical trial that is designed to determine how and when breast feeding transmission occurs. The Foundation project will build on the information we are learning from this trial try and understand what features about the mothers' viruses makc it more likely to be transmitted to her infant. For example, how does the genetic makcup of the virus influence transmission and is there a common genetic signature to viruses that infect infants? We are also interested in determining whether the amount of virus that mother has, including virus in breast milk, increases the chances of her infant being infected? AIDS researchers have already shown how to decrease transmission to newborns with a short course of AZT around the time of delivery. Now, we are trying to understand how to develop other ways to reduce HIV transmission to children in situations where access to expensive treatments are impractical. Jan-22-99 , 18:05 From-EGPediat AIDSFdtn 2023712044 T-484 P.32/33 F-312 2. How will your research under the Foundation grant be implemented in the pediatric HIV/AIDS population? One overall goal of studying breast milk transmission of HIV is to provide information to women so that they can make more informed choices about breast feeding. From the viral studies we hope to undertake over the next five years, we hope to understand a lot more about viruses in breast milk SO that we can begin to think about therapies more designed to target those viruses. Up to this point, there has been a heavy focus on HIV in the woman's blood. Much of transmission to the infant is actually going on during delivery, while they are in the birth canal. Or, in developing countries, a lot of infection is occurring through breast fecding when they are exposed to the virus in breast milk. We want to now start looking at those secretions and understand what is going on so that people can think more about intervention to target those viruses, instead of just blood viruses. 3. What does funding from a Foundation such as ours mean to your creativity as a scientist? A lot of what I see from the Glaser Foundation is not just individual creativity but a lot of encouragement to interact and be creative as a group. 3. What does it mean to be an Elizabeth Glaser Scientist? For those of us in the AIDS community, Elizabeth Glaser is one of the heroes who proves that one individual, if they work hard and have a lot of personal strength, they can make good things happen out of something that is inherently bad. I personally feel very proud to have funding from a group that bears her name. 4. This year marks the Foundation's 10th Anniversary. We have come so far in the past decade, what might the next decade of progress on pediatric HIV/AIDS research look like? I think there is a big mental shift that needs to take place (and hopefully will occur in the next decade) -- and that is what to do in developing countries where the therapies used to block HIV vertical transmission aren't really available? 1 think the next decade of AIDS research might be trying to come up with therapeutic approaches that are affordable and applicable in developing countries. That will be both a big political and scientific hurdle. That is really going to be the focus in terms of a lot of rethinking on how to deal with the problem of vertical transmission. The progress we have made in reducing vertical transmission in some settings has given may AIDS researchers renewed enthusiasm, and we need to continue to design better and better therapies for people who have access to Jan-22-99 18:05 From-EGPediatr :AIDSFdtn 2023712044 T-484 P 33/33 F-312 high quality health care. At the same time, the success in blocking HIV vertical transmission should serve as a source of encouragement to try to understand how the therapies we now have work and then figure out less costly approaches to accomplish the same aim, We have to remember that most HIV transmission is occurring in developing countries, and in it is this setting that we face our major challenge for halting the worldwide devastation of HIV. 24 Jan-22-99 17:58 FromEGPediatricAlDSFdtn 2023712044 T-484 P.01 F-312 ELIZABETH GLASER PEDIATRIC AIDS FOUNDATION 805 15th Street NW, Suite 500, Washington, DC 20005 Tel: 202-371-0099 Fax: 202-371-2044 FAX TRANSMISSION SHEET TO: Marsha Berry, Press Office Julie Mason, Press Office Noa Meyer, Speechwriting Office Patty Solis, Scheduling Office FROM: Linda Marson, Communications Director PHONE: 202-371-0099 (work) 301-983-8274 (home) and FAX: 202-371-2044 DATE: January 22, 1999 RE: ELIZABETH GLASER SCIENTIST AWARDS - PRESENTED BY FIRST LADY HILLARY RODHAM CLINTON AT THE NATIONAL PRESS CLUB, JANUARY 28, 1999 Number of pages (including this page): Hello and thank you to all of you. We are really excited about having the First Lady present the Foundation's Scientist Awards. ATTACHMENTS: O THIS TWO PAGE COVER SHEET LOGISTIC MEMO - Labeled A through G BACKGROUND MATERIALS - labeled 1-24 I am sending you all the same background information. Do you need proposed talking points? ? Please note that this year commemorates the Foundation's 10th Anniversary and also the attached release on the recently announced FDA regulations involving drugs for children. Paul Glaser will note the Administration's efforts in his introductory remarks for Mrs. Clinton. Please let me know each of your necds beyond the attached material and we will accommodate you every step of the way! (page one of two, cover memo) cover memo lof2 Jan-22-99 17:58 From-EGPediatricAIDSFdtn 2023712044 T-484 P.02 F-312 Attached is an updated agenda/logistical memo that reflects confirmation of the First Lady's arrival time at the National Press Club. This is a PROPOSED agenda and timeline, please let me know your questions, concerns, changes. I tried to provide as much detail as possible in this memo, particularly the logistics of her actually presenting the four awards to the scientists. Please advise us on what you need from us to accommodate security clearance re: staff, guests and media. I've attached our DRAFT MEDIA ADVISORY and DRAFT PRESS RELEASE. We would love a quote from the First Lady, if possible THANK YOU! (Page two of two, cover memo) Cover memo 2 of 2 # Jan-22-99 17:58 From-EGPediatricAIDSFdtn 2023712044 T-484 P.03 F-312 ELIZABETH GLASER PEDIATRIC AIDS FOUNDATION Co-tounders Classin Glaser 1947 1994 January 22, 1999 - UPDATED MEMO Susan DeLaurentiz Same Leegen Board of Directors To: Marsha Berry, Julie Mason, CHAIRFERSON l'out Closer Noa Meyer, Patti Solis Peter Benzion Bon Barkett Office of First Lady Marking Canter Phitap inco M.I) Hillary Rodham Clinton Susin Zangen Lloyd Zeiderman Chief Executive Officer From: Linda Marson, have Care Executive Director Communications Director Janis Sprie Executive Advisory Board CONTACT: 202-371-0099 (work) and HONDRARY O-CHAIR 301-983-8274 (home) President and Mrs. Ronald Rengan Mrs William E. Brock FAX: 202-371-2044 Allred A. Checota Kathryn D Checchi King Datentas Michael D. Eigher RE: FIRST LADY Smake Bold Senator Powa Howkits HILLARY RODHAM CLINTON'S Ellon John Michael S Ovit? PRESENTATION Grewn Spirlberg Jonathan M Tuch OF THE ELIZABETH GLASER Alexander Vregland Mrs Per Wilson SCIENTIST AWARDS ON Bobbi Zitkin Health Advisory Board JANUARY 28, 1999 CHAIRPERSON Catherine Willers MD. screensing AIDS Coundanon Thank you! Mary G Boland, RN. MS Children's Heapital of Yvenne J. Bryson, M.D. UST Selend of Below is a proposed rundown for the event. Please tell us what Mark Feinberg, M.D.. I'll D. Francy Cleaner for AIDE Research you need regarding background, talking points, security needs, Michael S Cottieu MD Maintaint C. Heligarly. M.D etc. We will accommodate you as requested. Colorable University, licricm David L) HJ. M.D. Added AIDS Received Conner Anna Rate Kaufran, M ΓA. M.A I have also attached a draft media advisory and a draft press Chancel As Therapore Daniel V. Lenders, M.D release. We will get you background information on all the Mager WASHING inspital Joseph M. McCune. M.D. Ph.D participants at the award ceremony, including a description of Grede 1,100 James Oleske, MD., M PH. the scientists work in layperson's terms, which will be helpful No. School Catherine S. Peckharn, MD since Mrs. Clinton will be presenting them with their award Increase at Chard Health, Landen Philip A. Pizzo, M.D and describing, in layperson terms, their work. Horoard Medical Heaptel Paolo Ross. M.D University of Rente and Institute Arge Revinstein, M.D. The audience for this event will include approximately 75 Attain Instinct 11. Called of Medicale Gwendolyn B Scott. M.D University n/ Minmi School of members of the scientific community, as well as staff and friends Γ. Richard Suchm, MD. 1001 ^ School of Medicare of the Foundation. In addition, the media is being invited to attend Lan Wiener, Ph D., " C.S.W. 2950 31st Street, Suite. 125. Sunra Manica, Colifornia 90405 Tel (310) 314-1459 Fax (310) 314-1-169 www.pedAIDS.org Nauager institute of Health 805 15th Street NW, Suite 500. Washington. DC 20005 Tel: (202) 371-0099 Fax: (202) 371-2044 Jan-22-99 17:58 From-EGPediatr AIDSFdtn 2023712044 T-484 P.04 F-312 the awards presentation. There will be no Q&A while the First Lady is in attendance. We plan to have an informal Q&A session with the press, our Foundation members and our scientists, following her departure. Here is a proposed rundown for the event: EVENT: The Elizabeth Glaser Pediatric AIDS Foundation's Scientist Awards ceremony will take place at the National Press Club, 14th and F Streets, NW, 13th floor, Holeman Lounge, on Thursday, January 28, 1999. GREETING: It is our understanding, per Patti Solis, that Mrs. Clinton will arrive at the Press Club at 9:50 a.m. She will be greeted (please advise us on where you wish this to take place?) by Foundation Chairman of the Board, Paul Glaser, Foundation CEO, Kate Carr, and Foundation Co-Chair Susie Zeegen. PHOTOS: We have a "holding room" adjacent to the Holeman Lounge, where the award ceremony is taking place, available for the purposes of photos with our the three Foundation members listed above, as well as the four scientists (and, if possible, their spouses?). Please advise us on what you need for security purposes. PROPOSED TIMELINE: 9:50 a.m. Mrs. Clinton arrives at the National Press Club, 14th and F Streets, NW. Greeted by Foundation contacts, Paul Glaser, Kate Carr and Susie Zeegen. Location: ? B Jan-22-99 17:58 From-EGPediatricAIDSFdtn 2023712044 T-484 P.05 F-312 9:53 a.m. Photo session (White House photographer and a Foundation photographer) with Paul Glaser, Kate Carr, Susie Zeegen, Janis Spire, Executive Director of the Pediatric AID Foundation and the four awardees/scientists: Dr. Doms, Dr. Goulder, Dr. Johnson, Dr. Overbaugh and their spouses? Location: "holding room" adjacent to Holeman Lounge. *Please note that a few board members may also request photos, if that is possible? 9:59 a.m. Enter Holeman Lounge. Mrs. Clinton can enter through the adjacent "holding room" and proceed directly to a seat next to the podium. She can remain seated until formally introduced for remarks and the award presentation. Jan-22-89 17:59 From-EGPediatricAlDSFdtn 2023712044 T-484 P.06 F-312 10:00 -10:02 a.m. Begin Award Ceremony - Opening remarks and welcome by Kate Carr, Chief Executive Officer, Elizabeth Glaser Pediatric AIDS Foundation. Introduces Susie Zeegen. 10:02-10:04 Remarks by Susie Zeegen, Co-Founder, Elizabeth Glaser Pediatric AIDS Foundation. Introduces Mary Fisher. 10:04-10:08 Remarks by Mary Fisher, Founder of Family AIDS Network. Introduces Paul Glaser. 10:08-10:13 Remarks by Paul Glaser, Chairman of the Board, Elizabeth Glaser Pediatric AIDS Foundation 10:13-10:14 PAUL GLASER INTRODUCES THE FIRST LADY 10:14 - 10:24 FIRST LADY delivers her remarks from the podium. We will provide suggested talking points: - Her history with the Foundation Jan-22-99 17:59 From-EGPediatricAIDSFdtr 2023712044 T-484 P.07 F-312 - the work of the Foundation,need to promote innovative, collaborative research, impact of Foundation's research on Pediatric HIV/AIDS and the meaning of the award 10:24 - 10:35 ASKS THE AWARDEES TO JOIN HER AT THE PODIUM, two on each side of her. Mrs. Clinton continues her remarks - introducing each of the scientists in turn, providing a - layperson description of the four who are being honored. She gives each of them their award in turn. (the awards themselves will be on a small table, adjacent to the podium). All 4 scientists remain standing until she has concluded. AWARDEES: Robert Doms, M.D., Ph. D., University of Pennsylvania O Jan-22-99 17:59 From-EGPediatricAlDSFdtn 2023712044 T-484 P.08 F-312 Philip J.R. Goulder, M.R.C.P., D. Phil., Massachusetts General Hospital Paul Johnson, M.D. Harvard Medical School Julie Overbaugh, M.D., Fred Hutchinson Cancer Center 10:35 Mrs. Clinton Concludes the awards presentation. Paul Glaser joins her at the podium. 10:35 Paul Glaser thanks Mrs. Clinton, who departs through the adjacent holding room. 10:40 Mrs. Clinton departs Press Club 10:36 a.m. Paul Glaser introduces Paula Apsell, Executive Producer, NOVA, who Introduces clip from PBS Special "Surviving AIDS," featuring Foundation Scientist Catherine Luzuriaga Jan-23-99 17:59 From-EGPediatricAIDSFdtr 2023712044 T-484 P.09 F-312 10:38-10:40 Paula Apsell introduces NOVA clip 10:40-10:46 NOVA Clip airs 10:46 Paul Glaser or Susie Zeegen conclude the Speakers program. 10:46-10:55 Susie Zeegen and Paul Glaser conduct Q&A With the media Note: Also seated but not speaking will be Janis Spire, Executive Director of the EG Pediatric AIDS Foundation and Catherine Wilfert, Scientific Director, EG Pediatric AIDS Foundation. 5 # Jan-22-99 18:02 From-EGPediatricAlDSFdtn 2023712044 T-484 P 21/33 F-312 For Immediate Release Contact: Kelli O'Reilly November 27, 1998 (310) 314-1459 FDA REGULATIONS ON DRUGS FOR CHILDREN ANNOUNCED ELIZABETH GLASER PEDIATRIC AIDS FOUNDATION: "THIS MEANS THAT, FINALLY, CHILDREN CAN SHARE IN RESEARCH PROGRESS" (WASHINGTON, D.C.) - The Federal Food and Drug Administration (FDA) today released final regulations outlining its authority to require pharmaceutical manufacturers to study their products for safety and effectiveness for use by children. The Elizabeth Glaser Pediatric AIDS Foundation, which has relentlessly pressed the FDA for such regulations, expressed its great pleasure at the release of the final regulations. "Simply put, these regulations mean that -- finally -- children can share in the research progress against disease," said Paul Glascr, Chairman of the Board of the Foundation and the father of an HIV-infected child. "Most of the time, children have been an afterthought in pharmaceutical research," said Susan DeLaurentis, a co-founder of the Foundation. ""Drug companies have failed to study drugs for safety in children for decades, largely because children are a very small market that doesn't make a big profit. My friend and fellow co-founder, Elizabeth Glaser, was shocked to find that the drugs that were available to treat her for AIDS were not available for her young daughter as well. The current drug company practice is that drugs are not studied for children unless there is a special reason to do so. These regulations will change that practice so that drugs for kids will be studied unless there is a reason not to do so. These regulations will make the future better for children with HIV ] and for all sick children. The Foundation is grateful to President Clinton, First Lady Hillary Rodham Clinton and Vice President Gore for their help in making these regulations a reality," added Susan DeLaurentis. "Separate pediatric studies are needed," said Catherine Wilfert, Medical Director of the Foundation. "Children are not simply little adults. Children - especially young children-metabolize drugs differently and have different reactions to drugs than grownups do. The failure of drug companies to do these studies means that parents and FDA release lof 2 Jan-22-99 18:02 From-EGPediatricAlDSFdtn 2023712044 T-484 P.22/33 F-312 pediatricians have to choose between ignoring a drug that is effective in adults or exposing a child to a drug of unknown safety. They shouldn't have to make that choice." The mission of the Elizabeth Glaser Pediatric AIDS Foundation is to identify, fund and conduct critical pediatric AIDS research that will lead to the prevention and treatment of HIV infection in infants and children. This commitment to stimulating collaborative and focused research is unique in the scientific community. # FDA release 20f2 13 Noa A. Meyer 10/26/98 12:00:01 o PM Record Type: Record To: Laura E. Schiller/WHO/EOP, Christine N. Macy/WHO/EOP CC: Subject: Gay and Lesbian Accomplishments There are two documents since Robin is still in the process of merging them. The second one is difficult to open, so I cut it and and it is the attached text. Therefore, no need to open Todd Sommer's doc. THE CLINTON ADMINISTRATION A RECORD OF FIGHTING THE AIDS EPIDEMIC Our common goal must ultimately be a cure, a cure for all those who are living with HIV, and a vaccine to protect all the rest of us from the virus. A cure and a vaccine: that must be our first and top priority. - President Clinton, December 6, 1995 It has been more than 15 years since the epidemic of HIV/AIDS struck our nation. In that time, more than 640,000 Americans have been diagnosed with AIDS and more than 385,000 men, women, and children have died of AIDS. President Clinton has worked hard to reinvigorate the response to HIV and AIDS, providing new national leadership, substantially greater resources, and a closer working relationship with affected communities. Funding for AIDS research has increased by over 65%, and funding for HIV prevention has increased 32%. Funding for the Ryan White CARE Act has increased by over 280%. The Food and Drug Administration has accelerated its drug approval process to record times, taken steps to increase access by women to clinical trials, and issued a new rule requiring better data collection on children. The President has preserved the Medicaid program, providing care to 50 percent of people with AIDS, including 92 percent of children with AIDS. The Centers for Disease Control estimate that as many as 900,000 Americans may currently be living with HIV or AIDS, and 40,000 to 60,000 Americans are being infected with HIV every year. Women, communities of color, and adolescents are experiencing particularly high rates of infection, with over half of new infections occurring in those under 25 years of age. That is why President Clinton will continue to work to ensure that our nation responds aggressively and compassionately to the challenges created by HIV and AIDS. This fight will not be over until we have a cure and a vaccine to protect all Americans from this deadly epidemic. PROVIDING NATIONAL LEADERSHIP Creating the White House Office of National AIDS Policy. Acting as representative to the President, this office brings greater visibility and direction to the war on AIDS by coordinating and focusing federal AIDS policy and initiatives. Appointing a National Advisory Council. The President created the Presidential Advisory Council on HIV/AIDS to provide him and his Administration with expert outside advice and clear recommendations on how the federal government should respond to the AIDS epidemic. Developing a National Strategy. President Clinton convened the first White House Conference on HIV and AIDS as well as the first White House Native American AIDS Policy meeting to encourage multi-level cooperation and a continued dialogue between the various communities fighting this epidemic. Fighting Discrimination. President Clinton supported the Kennedy-Kassebaum Health Insurance and Portability Act, which bans insurance discrimination against people with pre-existing conditions including HIV/AIDS. He led the fight to repeal the discriminatory ?Doman Amendment,? which would have discharged all HIV+ military personnel; and continues to enforce the Americans with Disabilities Act, which prohibits discrimination against people living with HIV/AIDS. Additionally, the Administration has resolved nearly 800 cases alleging employment discrimination, obtaining monetary benefits of over $6.1 million. Pushing for an AIDS Vaccine. On May 18, 1997, the President challenged the nation to develop an AIDS vaccine within the next ten years. He has supported that goal by dedicating an AIDS vaccine research center at the National Institutes of Health and encouraging domestic and international collaboration among governments, medical communities and service organizations. INVESTING IN RESEARCH Supporting the National Institutes of Health. The Administration has increased NIH AIDS research funds by 67% in five years. In 1993, President Clinton signed the NIH revitalization Act creating a permanent Office of AIDS Research at NIH and investing it with new authority to plan and carry out the AIDS research agenda. He appointed Nobel Prize winner Dr. Harold Varmus to head NIH and world-renowned immunologist Dr. Neil Nathanson to head OAR. Accelerating AIDS Drug Approval Process. Since 1993, the Food and Drug Administration has approved 9 new AIDS drugs, 20 new drugs for AIDS-related conditions, and three new diagnostic tests. Included in the approvals are drugs known as protease inhibitors, which in combination with previous drugs have shown tremendous promise in the treatment of HIV progression. Reducing Perinatal Transmission of HIV. The President is working aggressively with states to eliminate perinatal transmission of HIV. As a result of Public Health Service guidelines recommending the use of AZT by HIV+ pregnant women, the number of infants with perinatally acquired HIV dropped 43 percent between 1992 and 1996. Developing the Forum for Collaborative HIV Research. This new public-private group is designed to catalyze collaborations among government researchers, pharmaceutical companies, third-party payers, and the community to capitalize on recent scientific advances and learn how to optimally use available treatment regimens. INVESTING IN CARE Supporting the Ryan White CARE Act. President Clinton in five years has nearly tripled funding for the Ryan White CARE Act, the largest distributor of funds for medical and support services to people living with HIV and AIDS. In 1996, Ryan White funds were first earmarked for the AIDS Drug Assistance Program (ADAP) to help States assist those without insurance to obtain much needed prescription drugs; since then, ADAP funds have increased by over 780%. Providing Housing and Mental Health Assistance. Since coming to office, President Clinton has more than doubled funds for the Department of Housing and Urban Development's Housing Opportunities for People With AIDS (HOPWA) program. He also awarded the first federal grants though the Substance Abuse and Mental Health Administration to develop comprehensive mental health services for persons living with HIV/AIDS as well as their families and partners. Protecting Medicaid and Social Security coverage. The President fought to preserve Medicaid coverage for people living with AIDS. Nearly 50% of people with AIDS and 92% of children with AIDS rely on Medicaid for health coverage. He also revised eligibility rules for Social Security Disability Insurance to increase the number of HIV + persons who qualify for benefits. INVESTING IN PREVENTION Supporting the Centers for Disease Control. The Administration has increased funds for HIV prevention at the CDC by 32% in five years. Under the leadership of the Clinton Administration, the CDC reorganized its AIDS prevention efforts to foster greater overall coordination and enhance efforts to reduce sexually transmitted diseases and tuberculosis. The President appointed Dr. Jeff Koplan to head the CDC and Dr. Helene Gayle to head the CDC?s Center for HIV, STD & TB Prevention. In addition, President Clinton appointed former CDC Director Dr. David Satcher as the nation's Surgeon General. Reaching Out to Local Communities. President Clinton launched a nationwide HIV prevention community planning process to give local communities more authority over the shape and direction of AIDS prevention efforts. He also launched the Prevention Marketing Initiative, focusing on the risk to young adults with frank public service announcements recommending both sexual abstinence and the consistent use of latex condoms. Keeping Water Clean. The President issued combined CDC and Environmental Protection Agency guidelines recommending steps to purify drinking water in vulnerable populations against Cryptosporidium, which can be fatal to those with compromised immune systems. Increasing Access to HIV Prevention Services for Youth. In a directive issued on World AIDS Day 1997, President Clinton instructed each Federal agency to identify all programs under its control that offer opportunities to youth for preventing HIV infection and develop within 180 days a plan through which those programs can increase preventative education as well as support services for those already infected. Forwarded by Noa A. Meyer/WHO/EOP on 10/26/98 12:00 PM 0 Robin J. Bachman 10/26/98 11:35:20 AM Record Type: Record To: Noa A. Meyer/WHO/EOP CC: Brenda B. Costello/WHO/EOP Subject: Accomplishments gay98.dft Forwarded by Robin J. Bachman/WHO/EOP on 10/26/98 11:33 AM Todd A. Summers 10/23/98 01:23:29 PM Record Type: Record To: Robin J. Bachman/WHO/EOP, Richard Socarides/WHO/EOP cc: Subject: Accomplishments Here's the updated HIV/AIDS accomplishments - I checked the civil rights cases with Paul Richard - I'll forward his email - Liz Savage from Justice said they've done very few new ones (5?). I'll be available through signal - on my way to NYC. I think the final should be vetted through OMB - Richard Turman before it goes out!!! I also think we should add something on the CBC initiative, which is not yet crystallized but which we're announcing on Wednesday. Todd ACMP1098.d gay98.dft Page 1 The Clinton-Gore Administration A Record of Progress for Gay and Lesbian Americans "[W]e have to make sure that for every single person in our country, all Americans means all Americans." -- President Clinton, November 8, 1997 "It is time for all Americans to recognize that the issues that face gays and lesbians in this country are not narrow, special interests, they are matters of basic human and civil rights" --Vice President AI Gore, September 15, 1997 Fighting Discrimination and Hate Fighting Anti-Gay and Lesbian Hate Crimes. Last year, the President announced his sponsorship of the Hate Crimes Prevention Act during the historic White House Conference on Hate Crimes. This crucial legislation would strengthen and expand the ability of the Justice Department to prosecute hate crimes by removing needless jurisdictional requirements for existing crimes and by giving Federal prosecutors the power to prosecute hate crimes committed because of the victim's sexual orientation, gender or disability. The President and Vice President continue to push Congress to pass this important legislation and to speak out against hate. As the Vice President said on September 19, 1998: "If we allow even a small number of Americans to harbor and act upon malice and intolerance, we all feel the bitter sting of injustice. Let us send a clear message to those would commit crimes of hate: it is wrong, it is illegal, and we will punish you with the full force of our laws Crimes of hate against all people -- including gays and lesbians --should carry a punishment that is swift and severe. " In addition to advocating the adoption of the current legislation, as part of the 1994 Crime Act, President Clinton signed the Hate Crimes Sentencing Enhancement Act, providing for longer sentences where the offense is determined to be a hate crime. Ending Discrimination Against Gays and Lesbians in the Federal Civilian Workforce. President Clinton issued an Executive Order prohibiting discrimination based on sexual orientation in the Federal civilian workforce. This makes the Federal Government the largest employer in the world (1.8 million civilian employees) with a non-discrimination policy covering sexual orientation. And the President, working with a coalition in the House of Representatives, successfully defeated an attempt to overturn this policy. The President also issued an Executive Order mandating gay98.dft Page 2 that security clearances no longer be denied based on sexual orientation. Fighting Discrimination in All Workplaces. President Clinton and Vice President Gore endorsed and are fighting for passage of the Employment Non-Discrimination Act, a bill outlawing discrimination in hiring, firing and promotions based on sexual orientation, making them the first U.S. President and Vice President ever to back civil rights legislation for gays and lesbians. The legislation would ban discrimination based on sexual orientation in the workplace, extending basic employment discrimination protections to gay and lesbian Americans. Standing Up for Basic Fairness. President Clinton blocked Republican efforts to pass legislation prohibiting unmarried couples from jointly adopting children in the District of Columbia and legislation which would have denied federal housing money to localities with domestic partnership laws. Fighting Discrimination Against People With AIDS. President Clinton directed the Justice Department and the Equal Employment Opportunity Commission to vigorously prosecute those who discriminate against people with AIDS, leading to actions against health care providers and facilities that violate the Americans with Disabilities Act. Opposed Anti-Gay Ballot Initiatives. President Clinton strongly opposed anti-gay ballot initiatives in Colorado and Oregon. His two nominees to the Supreme Court voted to overturn Colorado's Amendment 2, declaring such initiatives unconstitutional violations of the Equal Protection clause of the Constitution. Fighting Discrimination Against People with AIDS in the Military. President Clinton successfully fought for the repeal of the Dornan amendment, which would have required the expulsion of all HIV-positive military service members regardless of their ability to do their jobs. Prior to its repeal, President Clinton took the highly unusual step of unilaterally declaring the law unconstitutional and he instructed the Department of Justice not to defend it in court, becoming the first president since Franklin Roosevelt to take such action. Helping Those Fleeing Persecution Because of Their Sexual Orientation. President Clinton's Administration is the first ever to grant asylum for gays and lesbians facing persecution in other countries. He sent gay human rights activist Keith Boykin to Zimbabwe as part of an official United States delegation and he investigated human rights abuses of gays and lesbians there. Banning Insurance Discrimination. President Clinton fought for and signed the Kennedy-Kassebaum Health Insurance Portability and Accountability Act, which bans insurance discrimination against people with pre-existing medical conditions including HIV/AIDS. In addition, President Clinton issued a directive that ensures gay98.dft Page 3 that all providers of Federal health insurance abide by non-discrimination rules including sexual orientation. Fighting Harassment of Students Based on Sexual Orientation. President Clinton's Department of Education has issued landmark guidance that explains federal standards against sexual harassment and that prohibits sexual harassment of all students regardless of their sexual orientation. Welcoming the Contributions to Service of All Americans President Clinton has Appointed the Most Inclusive Administration in History. President Clinton is the first President to appoint an openly gay or lesbian person to an Administration post. The President has appointed more than 150 openly gay and lesbian appointees, including: Virginia Apuzzo, Assistant to the President for Management and Administration, the highest ranking openly gay or lesbian person ever to serve in the Federal Government and the first openly gay or lesbian Assistant to the President; Director of the U.S. Patent and Trademark Office Bruce Lehman, the first openly gay man to be confirmed by the U.S. Senate; Fred Hochberg, Deputy Administrator of the Small Business Administration, the first openly gay person to be appointed Deputy in a U.S. cabinet-level agency: Assistant Secretary of Housing and Urban Development Roberta Achtenberg, who served in this position from 1993 to 1995; Gail Shibley to serve as the Director of External Communications for the Federal Highway Administration; The President has also nominated, and continues to fight for, James Hormel to be U.S. Ambassador to Luxembourg -- if confirmed he would be the first-ever openly gay United States ambassador. Reaching Out to All Communities. This Administration is committed to a policy of inclusion. President Clinton named the first Presidential Liaison to the gay and lesbian community, Marsha Scott. Later, he named the first openly gay senior policy adviser on civil rights issues, Richard Socarides. He become the first sitting president to speak before a gay and lesbian organization on November 8, 1997, when he deliver the keynote address to the Human Rights Campaign National Dinner. In September 1997, the Vice President addressed a reception of the National Gay and Lesbian Task Force, the first Vice President to speak at a gay rights event. In 1998, the Vice President has spoken before the Human Rights Campaign in Washington, D.C. and the Empire State Pride Agenda in New York City. Both the President and the Vice President regularly meet with gay and lesbian leaders. gay98.dft Page 4 "I think if we really could create a society where there is opportunity for all and responsibility from all and we believed in a community of all Americans, we could truly meet every problem we have and seize every opportunity we have.' " -- President Clinton, November 8, 1997 10/98