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January 22, 1946
Dr. Frank E. Hoecker,
The University of Kansas,
Department of Physics & Astronomy,
Lawrence, Kansas
Dear Dr. Hoecker:
We are quite pleased to learn from your letter of
January 17th that you intend to do research in connection with the metabolism
of radium. This is a program which, if you will recall, we have contended for
some time required considerable work in order to definitely determine the
actual effects of radium or precise data on elimination and, if at all possible,
some indication at least as to what magnitude of a dose constitutes a tolerance
amount of radium. We realize, of course, that this is a fairly large program
to undertake but we would be glad to cooperate with you in any way possible
and we will be particularly pleased to receive from you results on the tests
conducted.
With reference to the two milligram source of radium
chloride, we will be very glad to prepare such a material for you. As you
probably realize, all of our radium is purchased as a bromide and it will be
necessary for us to convert a small portion of this to a chloride, but we can
doubtless do this within a few days time. Under the circumstances, we will be
willing to do this for practically the cost of having a technician do this
work and would be very glad, therefore, to supply this radium to you at a price
of $30.00 per milligram.
not
Whether we would have exactly two milligrams or not,
we can/ determine, but we can assure you that without our going to the trouble
of waiting for two weeks or a month to make the measurements that the material
supplied to you will be reasonably close to two milligrams.
With regard to the question of the outcome of our studies
with Dr. Flinn and Dr. Hess in connection with the relation between breath radon
concentration and rate of exhalation, we have to date been unable to draw any
definite conclusions. We have tabulated all our results and have submitted a
copy to Dr. Greenburg for additional study. If you would be interested in a
copy of these measurements, we would be glad to prepare a tabulation for you.
It is our belief that a much closer control on sampling would have to be
instituted in order to establish any definite relationship between the two
factors.
We have recently been working with Dr. Hess on a method
for determining the amount of radium in the body by direct gamma ray measurement
making use of the very delicate measuring equipment used by Dr. Hess. The
information collected to date is rather meager and no very definite conclusions
can be drawn. We will be conducting additional experiments probably within the
next eight or ten weeks and hope, at that time, to accumulate sufficient
additional data to provide information which lends itself to a reasonable
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"ocrText": "January 22, 1946\nDr. Frank E. Hoecker,\nThe University of Kansas,\nDepartment of Physics & Astronomy,\nLawrence, Kansas\nDear Dr. Hoecker:\nWe are quite pleased to learn from your letter of\nJanuary 17th that you intend to do research in connection with the metabolism\nof radium. This is a program which, if you will recall, we have contended for\nsome time required considerable work in order to definitely determine the\nactual effects of radium or precise data on elimination and, if at all possible,\nsome indication at least as to what magnitude of a dose constitutes a tolerance\namount of radium. We realize, of course, that this is a fairly large program\nto undertake but we would be glad to cooperate with you in any way possible\nand we will be particularly pleased to receive from you results on the tests\nconducted.\nWith reference to the two milligram source of radium\nchloride, we will be very glad to prepare such a material for you. As you\nprobably realize, all of our radium is purchased as a bromide and it will be\nnecessary for us to convert a small portion of this to a chloride, but we can\ndoubtless do this within a few days time. Under the circumstances, we will be\nwilling to do this for practically the cost of having a technician do this\nwork and would be very glad, therefore, to supply this radium to you at a price\nof $30.00 per milligram.\nnot\nWhether we would have exactly two milligrams or not,\nwe can/ determine, but we can assure you that without our going to the trouble\nof waiting for two weeks or a month to make the measurements that the material\nsupplied to you will be reasonably close to two milligrams.\nWith regard to the question of the outcome of our studies\nwith Dr. Flinn and Dr. Hess in connection with the relation between breath radon\nconcentration and rate of exhalation, we have to date been unable to draw any\ndefinite conclusions. We have tabulated all our results and have submitted a\ncopy to Dr. Greenburg for additional study. If you would be interested in a\ncopy of these measurements, we would be glad to prepare a tabulation for you.\nIt is our belief that a much closer control on sampling would have to be\ninstituted in order to establish any definite relationship between the two\nfactors.\nWe have recently been working with Dr. Hess on a method\nfor determining the amount of radium in the body by direct gamma ray measurement\nmaking use of the very delicate measuring equipment used by Dr. Hess. The\ninformation collected to date is rather meager and no very definite conclusions\ncan be drawn. We will be conducting additional experiments probably within the\nnext eight or ten weeks and hope, at that time, to accumulate sufficient\nadditional data to provide information which lends itself to a reasonable"
}