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EPA Actions To Date Centers for Children's Environmental Health and Disease Prevention Research: In September, 1997, HHS and EPA began to accept applications for six Centers to be funded in the initial year at $10 million. EPA's Office of Research and Development is contributing half of the funds and NIH's National Institute for Environmental Health Sciences is providing the other half. The Centers will be established by September, 1998 after an inter-agency peer review amount process. The Centers will conduct research that improves our knowledge regarding detection, treatment and prevention of environmentally related diseases in children. Research will focus on the possible environmental causes of children's illnesses and disorders, including understanding the mechanisms of respiratory disease, such as asthma. Applicants are also specifically invited to study the impact of common environmental contaminants, such as lead or mercury, on intellectual development. The successful applications for Centers grants will demonstrate how they will use part of their funds on a community-based prevention/intervention research project 5 Yr. grants 1 Announcement of grants TBD. US EPA Conference on Preventable Causes of Cancer in Children: On September 15 and 16, 1997, EPA hosted the first-ever national conference on "Preventable Causes of Childhood Cancer." Approximately 300 scientists, government officials, representatives of advocacy organizations and other members of the public participated. Health experts presented their perspectives on a broad range of issues including the special vulnerability of children to environmental toxins, studies on the role of parental occupational exposures, trends in childhood cancer, and methods used to study environmental factors in childhood cancer. Participants discussed specific recommendations and research strategies that will assist in assessing the current state of knowledge, and setting priorities for future research. Recommendations included: - better interdisciplinary and collaborative studies of suspected environmental causes and mechanisms of childhood cancer; - the establishment of a National Childhood Cancer Registry, standardizing information such as exposure history and family health data; - more joint prevention efforts between scientists and communities focused on high risk infants and children; and - better techniques for screening chemicals suspected of causing health effects in children. These efforts will contribute to a coordinated, comprehensive national research strategy to guide the nation in its efforts to protect children from cancer. The January issue of Environmental Health Perspectives will focus on the conference and prevention of children's cancer.