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To determine if any absorption did take place where stored,
and
fod
each
one
when and how eliminated we took 3 guinea pigs / 100 milligrams of luminous
paint containing 2.9 mg. of radium per 100 grams of paint, each day for 20 days.
The urine and feces were collected each day. After the animals had had 2
grams of the paint fed them, they were kept for an additional ten days during
which period the urine and feces were also collected but kept repante from
that of the lst 20 days. The animals were autopsied and
organs dissected
out. Because the organs were small and the amount of radioactive material
supposed to be present was minute we put the individual organs of the three
animals together.
Our findings were as follows:
Organs
Dry wt.
microgram radium element per gram of material
Heart
3.4189
5 x 10
-4
Lungs
3.4618
4.6 X 10
-4
Brains
3.3708
2 X 10
4
Spleen
2.9406
2.5 X 10
Liver
12.1291
2.5 X 10
Kidney
4.035
1.6 x 10
Musch after
burning
10.5
1.6 x 10-3
Bones after
buning
12.3
.02 micrograms
The feces for the 1st 10 days contained 1.55 micrograms per gram
burnt material. 2nd ten days - 1.75 micrograms per gram. burnt material.
10 days after feeding: 0.23 micrograms per gram.
The urine samples remained more or less constant for the entire
period and contained 2.5 x 10-2 micrograms per gram evaporated material.
An analysis of the original paint showed that 2 grams of the paint
contained .058 mg of radioactive material.
Our test showed that 97.85% of the material ingested was eliminated
within 10 days after the feeding stopped. The fact that radioactive
material was actually absorbed is proven by the fact that the urine was radio-
active as well as the various organs. The greater part of the radium retained
in the body was found to be deposited in the bone. The amount percent in the
other organs depended on the blood supply.
The jaws of 5 pigs were painted regularly each day for a period of
six months during which time each pig had 3 grams of paint painted on the
guns. Two months after the last application the pigs were killed and the
entire body burnt to an ash and examined for radium. As a control the bodies
of two intreated animals were also ashed.
Animal
Side Div.
lst read.
2nd read.
Average
Blank
60 - 50
197 sec
197 sec
197sec
A
#
194
188
191 sec
B
#
195
200
197.5
Blank
#
199
195
197.
C
Il
194
195
194.5
D
Il
194
196
195.
E
II
198
198
198
Blank
Il
198
197
197.5
A Repeated
II
191
192
191.5
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- Type
- photo
- Media ID
- 76af3f31dbbd67c3
- Size
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Document data
- ID
- 75721846
- Core
- doc
- Type
- document
DTO data
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"ocrText": "To determine if any absorption did take place where stored,\nand\nfod\neach\none\nwhen and how eliminated we took 3 guinea pigs / 100 milligrams of luminous\npaint containing 2.9 mg. of radium per 100 grams of paint, each day for 20 days.\nThe urine and feces were collected each day. After the animals had had 2\ngrams of the paint fed them, they were kept for an additional ten days during\nwhich period the urine and feces were also collected but kept repante from\nthat of the lst 20 days. The animals were autopsied and\norgans dissected\nout. Because the organs were small and the amount of radioactive material\nsupposed to be present was minute we put the individual organs of the three\nanimals together.\nOur findings were as follows:\nOrgans\nDry wt.\nmicrogram radium element per gram of material\nHeart\n3.4189\n5 x 10\n-4\nLungs\n3.4618\n4.6 X 10\n-4\nBrains\n3.3708\n2 X 10\n4\nSpleen\n2.9406\n2.5 X 10\nLiver\n12.1291\n2.5 X 10\nKidney\n4.035\n1.6 x 10\nMusch after\nburning\n10.5\n1.6 x 10-3\nBones after\nbuning\n12.3\n.02 micrograms\nThe feces for the 1st 10 days contained 1.55 micrograms per gram\nburnt material. 2nd ten days - 1.75 micrograms per gram. burnt material.\n10 days after feeding: 0.23 micrograms per gram.\nThe urine samples remained more or less constant for the entire\nperiod and contained 2.5 x 10-2 micrograms per gram evaporated material.\nAn analysis of the original paint showed that 2 grams of the paint\ncontained .058 mg of radioactive material.\nOur test showed that 97.85% of the material ingested was eliminated\nwithin 10 days after the feeding stopped. The fact that radioactive\nmaterial was actually absorbed is proven by the fact that the urine was radio-\nactive as well as the various organs. The greater part of the radium retained\nin the body was found to be deposited in the bone. The amount percent in the\nother organs depended on the blood supply.\nThe jaws of 5 pigs were painted regularly each day for a period of\nsix months during which time each pig had 3 grams of paint painted on the\nguns. Two months after the last application the pigs were killed and the\nentire body burnt to an ash and examined for radium. As a control the bodies\nof two intreated animals were also ashed.\nAnimal\nSide Div.\nlst read.\n2nd read.\nAverage\nBlank\n60 - 50\n197 sec\n197 sec\n197sec\nA\n#\n194\n188\n191 sec\nB\n#\n195\n200\n197.5\nBlank\n#\n199\n195\n197.\nC\nIl\n194\n195\n194.5\nD\nIl\n194\n196\n195.\nE\nII\n198\n198\n198\nBlank\nIl\n198\n197\n197.5\nA Repeated\nII\n191\n192\n191.5"
}