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OCR Page 1 of 3UNIVERSITY OF MISSOURI
COLUMBIA
DEPARTMENT OF CHEMISTRY
March 17th, 1931
Mr. . H. H. Barker
United States Radium Corporation
535 Pearl Street
New York City, New York
MAR 19 1931
My dear Barker:
I wish to thank you for your cooperation in
sending to Mr. Horace Thomas the compilation of literature
on the therapeutic effects of radium taken internally. I
took the package over to his house yesterday. He is sick
abed at this time with a mild attack of flu; but he will
make extracts of papers and I shall see to it that the book
is returned to you within a week. I may add that last week
the students and staff in the Department of Anatomy held
their regular weekly seminar meeting at which Horace Thomas
was the principal speaker. He gave a criticel summary of
the work which he had read on the physical effects of radium
taken internally. I must say that he m'ade a very good sum-
mary. I now feel that we have a man of the type who is
capable of conducting some good experiments. The members
of the staff of the Department of Anatomy, including the
Dean of the Medical School, asked some questions and made
valuable suggestions. The cooperation of this group is in-
sured and my next step shall be to get a student in Chemistry
who will cooperate with Thomas in making the numerous radium
determinations which the work will involve. I think I have
such a man in sight and if he has a little time right soon,
we shall start him on the emanation method and particularly
the bisulfate fusion method of determining radium.
I can show him about the care that must be
taken in carrying out the work for I am now in the midst of
making the radium determinations on the feces and urine
residues of the New Jersey girls. I am doing the radium de-
terminations on the feces residues now at the rate of about
three per day. Within another week I hope to have this phase
of the work complete. Then there will remain about 15 or 20
samples of urine residues which are in nitric acid storage now.
Probably it is too early to make any statement
about the trend of the radium determinations. We may get some
surprises when we come to examine the urine specimens, but I
had anticipated some rather active samples of feces residues.
So far I have been rather disappointed in this phase of the
work. In fact, I did not proceed with due scientific caution
in preparing the samples for assay of radium: instead of do-
ing a preliminary determination on the series of residues
which arrived after the administration of some of the drugs
administered to reduce the radiun content of the patients, I
weighed out samples for the entire series of approximately
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