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06/29/98 MON 09:17 FAX 202 690 7425 OPHS EXECUTIVE OFFICE 002 JUN 23'98 14:02 FR CDC/OSH-OD 97704885767 TO 912026906960 P.02/10 JUN.22.1998 2:37PM AMA SCIENCE NEWS NO.156 P.2/4 American Medical Association HEALTH Physicians dedicated to the health of America TOBACCO- Minorities News Release EMBARGOED FOR RELEASE: 3 p.m. (CT) Tuesday, July 7, 1998 Media Advisory: To contact Ralph S. Caraballo, Ph.D., call the CDC Office on Smoking and Health at 770/488-5493. To contact Eliseo J. Pérez-Stable, M.D. call Lordelyn del Rosario at 415/476-2557. To contact Edward M. Sellers, M.D., call the Univ. of Toronto public affairs office at 416/978-5949. African American Smokers Have Higher Levels of Metabolized Nicotine Than Whites, Mexican Americans Difference may help explain more difficulty in quitting, higher lung cancer rates among African Americans CHICAGO-African American smokers have higher serum cotinine levels than do white or Mexican American smokers, even when taking into account the number of cigarettes smoked, according to an article in the July 8 issue of The Journal of the American Medical Association (JAMA). An average of 70 percent to 80 percent of nicotine absorbed into the body from cigarette smoke is metabolized to cotinine. Cotinine in the blood is believed to be a marker of both tobacco use and exposure to environmental tobacco smoke. Ralph S. Caraballo, Ph.D., from the Centers for Disease Control and Prevention, Atlanta, and colleagues investigated differences in levels of serum cotinine in African American, white and Mexican American cigarette smokers in the U.S. adult population. The researchers obtained data on serum cotinine levels from a representative sample of adult smokers and nonsmokers of the Third National Health and Nutrition Examination Survey (NHANES III), a nationwide household collection of health and nutritional information from a representative sample of the U.S. civilian population. From this data, they found that although African Americans were as likely to have smoked in the past five days 2S whites, they reported smoking fewer cigarettes per day than whites. Mexican Americans smoked fewer cigarettes per day than did either blacks or non-Mexican American whites. --more-- Jen Molter Director 615 North State Street 312 464 5374 Department of Science News Chicago, Illinois 60610 812 464 5839 Fax