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Dr. Ewing - 2 -5-27-32
animals, dogs and sheep. Those projected experiments demand
trained workers in radioactivity and in biology as well as a
far larger outlay for animals.
2. Another experiment started late last fall
is being conducted in cooperation with the Elgin State Hospi-
tal near Chicago. Known quantities of soluble radium salts
have been administered at regular intervals to a selected
group of 30 patients, most of them being dementia praccox
cases; Mr. Paul Morris and I have made one series of radium
measurements on these patients with the object of determining
the percentage of radium retained. The first series of mea-
surements stands out in the contrast between high fraction of
emanation continually exhaled by this group in comparison
with the girls who contracted radium poisoning nearly fifteen
years ago. Early next month a second serios of heasurements
will be made on these patients, no radium having been adminis-
tered during the past six months. Those projected experiments,
we hope, will throw some light or the rate of "fixation" of
radium in the system.
3. Probably fully live years have passed since
the Menorial Hospital through the courtesy of Dr. Failla sup-
plied us with a source of polonium. Nearly two years ago we
reported that the polozium source was rendering good service.
At this time we are happy to forward a report on the physiolo-
gical effects of the alpha particle, issued in the form of a
dissertation for the dostorate by Mr. Raymond E. Zirkle. These
experiments which were parried on under the immediate direction
of W. J. Robbins, Dean of the Graduate School, open a funda-
mental field of investigation involving the use of the alpha
particle as an instrument of research. We are anxious to ex-
tend our stad/y on the physiological effects of the alpha par-
ticle and apply its agtion to other fields such as genetios.
4.
Since 1918 the University of Missouri has
maintained a refining laboratory for radioactive substances.
The refining of mesothorium has been continued ever since, and
during its period of operation the laboratory was refined about
4,000 milligrams of this radioactive element, expressed as
radium equivalent. This work has been carried out mainly by
graduate students working under the direction of Dr. G. F.
Breckenridge and myself. The maintenance of a refining labora-
tory has furnished three distinct lines of investigation:
(a) Radiothorium, a product of mesothorium, so valuable for
research work on the structure of the atom, has been conserved,
and has been supplied free of charge in most cases, to investi-
gators in this country and abroad (see attached sheet for list
of laboratories.) (b) Studies have been made bearing on the
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"ocrText": "Dr. Ewing - 2 -5-27-32\nanimals, dogs and sheep. Those projected experiments demand\ntrained workers in radioactivity and in biology as well as a\nfar larger outlay for animals.\n2. Another experiment started late last fall\nis being conducted in cooperation with the Elgin State Hospi-\ntal near Chicago. Known quantities of soluble radium salts\nhave been administered at regular intervals to a selected\ngroup of 30 patients, most of them being dementia praccox\ncases; Mr. Paul Morris and I have made one series of radium\nmeasurements on these patients with the object of determining\nthe percentage of radium retained. The first series of mea-\nsurements stands out in the contrast between high fraction of\nemanation continually exhaled by this group in comparison\nwith the girls who contracted radium poisoning nearly fifteen\nyears ago. Early next month a second serios of heasurements\nwill be made on these patients, no radium having been adminis-\ntered during the past six months. Those projected experiments,\nwe hope, will throw some light or the rate of \"fixation\" of\nradium in the system.\n3. Probably fully live years have passed since\nthe Menorial Hospital through the courtesy of Dr. Failla sup-\nplied us with a source of polonium. Nearly two years ago we\nreported that the polozium source was rendering good service.\nAt this time we are happy to forward a report on the physiolo-\ngical effects of the alpha particle, issued in the form of a\ndissertation for the dostorate by Mr. Raymond E. Zirkle. These\nexperiments which were parried on under the immediate direction\nof W. J. Robbins, Dean of the Graduate School, open a funda-\nmental field of investigation involving the use of the alpha\nparticle as an instrument of research. We are anxious to ex-\ntend our stad/y on the physiological effects of the alpha par-\nticle and apply its agtion to other fields such as genetios.\n4.\nSince 1918 the University of Missouri has\nmaintained a refining laboratory for radioactive substances.\nThe refining of mesothorium has been continued ever since, and\nduring its period of operation the laboratory was refined about\n4,000 milligrams of this radioactive element, expressed as\nradium equivalent. This work has been carried out mainly by\ngraduate students working under the direction of Dr. G. F.\nBreckenridge and myself. The maintenance of a refining labora-\ntory has furnished three distinct lines of investigation:\n(a) Radiothorium, a product of mesothorium, so valuable for\nresearch work on the structure of the atom, has been conserved,\nand has been supplied free of charge in most cases, to investi-\ngators in this country and abroad (see attached sheet for list\nof laboratories.) (b) Studies have been made bearing on the"
}